Transfusion最新文献

{"title":"Rethinking twin chimerism.","authors":"Robert E Wenk, Kayla M Sheets","doi":"10.1111/trf.18341","DOIUrl":"10.1111/trf.18341","url":null,"abstract":"","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":" ","pages":"1751-1755"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to Comparative changes of pre-operative autologous transfusions and peri-operative cell salvage in the United States.","authors":"","doi":"10.1111/trf.18372","DOIUrl":"10.1111/trf.18372","url":null,"abstract":"","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":" ","pages":"1765"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144804874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ABO-mismatched platelet and plasma transfusion practices and the potential for transfusion-related alpha-gal syndrome: The Biomedical Excellence for Safer Transfusion Collaborative Study.","authors":"Nancy M Dunbar, Richard M Kaufman, Karina S Bary, Gregory R M Bellairs, Claudia S Cohn, Fanny Delettre, Stephanie Ditcham, Gustavo C Duarte, Amanda Ellison, Roberta Fachini, Chloe E George, Catherine Humbrecht, Vernon Louw, Sascha Meier, Sarah Morley, Meridah Mwase, Nancy Robitaille, Kylie Rushford, Tomohiko Sato, Richard Schäfer, Julie Staves, Minoko Takanashi, Pierre Tiberghien, Silvano Wendel, Erica M Wood, Alyssa Ziman, Michael F Murphy","doi":"10.1111/trf.18338","DOIUrl":"10.1111/trf.18338","url":null,"abstract":"<p><strong>Background: </strong>Alpha-gal syndrome (AGS) is caused by IgE antibodies against the alpha-gal oligosaccharide, which is structurally similar to the Group B antigen. Recent case reports of severe allergic transfusion reactions (ATRs) in Group O patients receiving Group B plasma and platelets raise the possibility of a new adverse event, herein called transfusion-related AGS (TRAGS). The primary goal of this study was to assess the frequency of Groups B and AB plasma and platelet transfusions to Group O patients.</p><p><strong>Study design and methods: </strong>In this multi-site retrospective study, participating sites submitted the numbers of platelet and plasma transfusions administered during a 2-year period categorized by patient and product ABO group.</p><p><strong>Results: </strong>Fourteen sites from 10 countries participated. Group O patients received Group AB for an average of 9.9% (range 2.8%-29.2%) of plasma transfusions and Group B for 3.2% (0%-12.8%). AB plasma transfusion to Group O patients represented 4.5% (0.9%-14.6%) of the total plasma transfused; Group B 1.4% (0%-5.1%). Group O patients received Group AB for an average of 1.5% (range 0%-5.9%) of platelet transfusions and Group B for 4.1% (0%-14.2%). AB platelet transfusion to Group O patients represented 0.6% (0%-2.7%) of the total platelets transfused; Group B platelets were 1.8% (0%-6.7%).</p><p><strong>Discussion: </strong>Evidence supporting the possibility of a new adverse event, TRAGS, is accumulating. This study quantifies how often Group O patients may be exposed to Group B antigen in Group B or AB plasma and/or platelet transfusions, providing an estimate of the scope of potential risk for TRAGS.</p>","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":" ","pages":"1621-1629"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lead impregnation in blood donors in Algiers.","authors":"Smail Benbouabdellah, Salma Kaddour","doi":"10.1111/trf.18358","DOIUrl":"10.1111/trf.18358","url":null,"abstract":"<p><strong>Introduction: </strong>Lead exposure, even at low levels, can severely impact the neurological development of newborns, especially premature infants due to their low birth weight. Blood transfusion is an overlooked or unknown indirect exposure pathway.</p><p><strong>Objective: </strong>To quantify blood lead levels among blood donors in Algiers.</p><p><strong>Materials and methods: </strong>The study involved 484 donors from 16 transfusion centers in Algiers. A questionnaire assessed lead exposure sources, and blood samples were analyzed using inductively coupled plasma mass spectrometry (ICP/MS) to measure lead levels, with a decision threshold of 10 μg/L. The critical threshold for premature newborns has been set at 18 μg/L in the donor.</p><p><strong>Discussion: </strong>Thirty percent of donors had measurable blood lead levels, with 17.98% exceeding the critical threshold of 18 μg/L. No donors under 20 had measurable lead levels. Recent home renovations and kohl use were linked to higher lead levels. Occupational exposure, such as a car bodyworker with a lead level of 163.28 μg/L, poses a risk for low birth weight newborns receiving transfusions.</p><p><strong>Conclusion: </strong>Selection criteria for newborn transfusions should limit lead exposure, favoring young donors without recent lead exposure. Testing blood lead levels in donors could improve neonatal transfusion safety. Further research is required to refine critical thresholds and improve screening protocols.</p>","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":" ","pages":"1599-1608"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of a novel B allele with a nucleotide change (c.826G>T) responsible for B_el phenotype.","authors":"Jue Hou, Hongli Guan, Meng Li","doi":"10.1111/trf.18362","DOIUrl":"https://doi.org/10.1111/trf.18362","url":null,"abstract":"","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":"65 9","pages":"E58-E60"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145055873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel silenced RHCE variant with c.940-3C>G (IVS6-3C>G) in a Chinese individual.","authors":"Zhihui Feng, Ping Yan, Bin Hu, Shutao Pang","doi":"10.1111/trf.18351","DOIUrl":"https://doi.org/10.1111/trf.18351","url":null,"abstract":"","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":"65 9","pages":"E49-E51"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145055957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"SUPPLEMENT ARTICLE.","authors":"","doi":"10.1111/trf.18418","DOIUrl":"https://doi.org/10.1111/trf.18418","url":null,"abstract":"","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":"65 Suppl 2 ","pages":"7A-8A"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to \"Current advances in 2024: A critical review of selected topics by the Association for the Advancement of Blood and Biotherapies (AABB) Clinical Transfusion Medicine Committee\".","authors":"","doi":"10.1111/trf.18328","DOIUrl":"10.1111/trf.18328","url":null,"abstract":"","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":" ","pages":"1766"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144761442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Contemporary prehospital Emergency Medical Services in the United States: An overview and considerations for the Transfusion Medicine Community.","authors":"Matthew J Levy, Pampee P Young, Emily Coberly, John B Holcomb, Francis X Guyette, Randall M Schaefer, Jon R Krohmer","doi":"10.1111/trf.18348","DOIUrl":"10.1111/trf.18348","url":null,"abstract":"","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":" ","pages":"1738-1745"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144718737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identifying trauma patients who benefit from whole blood transfusion: An effect decomposition analysis on patient survival.","authors":"Crisanto M Torres, Allan E Stolarski, Kelly M Kenzik, Dane R Scantling, Aaron Richman, Noelle N Saillant, Joseph V Sakran","doi":"10.1111/trf.18346","DOIUrl":"10.1111/trf.18346","url":null,"abstract":"<p><strong>Background: </strong>Although whole blood (WB) transfusion has gained attention as a potentially superior alternative to component therapy (CT) for patients experiencing severe traumatic hemorrhage, conflicting evidence leaves its optimal use unclear.</p><p><strong>Methods: </strong>We conducted a retrospective review of adult trauma patients treated at civilian trauma centers participating in Trauma Quality Improvement Program (TQIP) from 2020 to 2021. All received either WB or CT within four hours of emergency department arrival. We assessed the effect of WB versus CT by examining key clinical parameters and performing an effect decomposition analysis.</p><p><strong>Results: </strong>Of 34,476 patients, 9023 (29%) received WB, while 25,453 (71%) received CT alone. Across the entire cohort, there was no statistically significant difference in adjusted odds of 24-h mortality (aOR 0.85 [95% confidence interval (CI) 0.73-1.01], p = .052). However, patients presenting with hypotension showed lower unadjusted and adjusted odds of death when given WB, including those with systolic blood pressure (SBP) below 90 mmHg (aOR 0.72 [95% CI 0.55-0.96], p = .02) and 70 mmHg (aOR 0.64 [95% CI 0.45-0.91], p = .01).</p><p><strong>Discussion: </strong>These findings suggest that the effectiveness of whole blood (WB) is influenced by several clinical characteristics. Arrival hypotension appears to play a key role, accounting for 13% of the mortality difference observed with WB versus CT. Future prospective trials are needed to define optimal patient selection and identify those most likely to benefit from WB in trauma resuscitation.</p>","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":" ","pages":"1609-1619"},"PeriodicalIF":2.0,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}