Transfusion最新文献_第3页

Correction to "Comparable bacterial growth in platelet concentrates suspended in plasma and platelet additive solution and improved detection of bacterial contamination using a new generation automated culture system". 更正 "悬浮在血浆和血小板添加剂溶液中的血小板浓缩物中的细菌生长情况相当，新一代自动培养系统对细菌污染的检测得到改进"。

IF 2.5 3区医学

Transfusion Pub Date : 2024-08-18 DOI: 10.1111/trf.17986

引用次数: 0

Correction to "Estimating Waiting Time for Compatible Blood: A Negative Binomial Approach". 对 "估计兼容血液的等待时间：负二项法"。

IF 2.5 3区医学

Transfusion Pub Date : 2024-08-17 DOI: 10.1111/trf.17976

引用次数: 0

Prediction of CD34+ hematopoietic stem cells in healthy allogeneic stem cell donors on the Optia cell separator based on CE2: Which formula is more correlated with actual CD34+? 基于 CE2 预测 Optia 细胞分离器上健康异体干细胞捐献者的 CD34+ 造血干细胞：哪个公式与实际 CD34+ 更相关？

IF 2.5 3区医学

Transfusion Pub Date : 2024-08-17 DOI: 10.1111/trf.17990

Sıdıka Gülkan Özkan, Ali Kimiaei, Seyedehtina Safaei, Tarık Ercan, Meral Sönmezoğlu, Gülderen Yanıkkaya Demirel, Sema Aktaş, Sinem Özdemir, Helin Serda Özalp, Hasan Atilla Özkan

{"title":"Prediction of CD34+ hematopoietic stem cells in healthy allogeneic stem cell donors on the Optia cell separator based on CE2: Which formula is more correlated with actual CD34+?","authors":"Sıdıka Gülkan Özkan, Ali Kimiaei, Seyedehtina Safaei, Tarık Ercan, Meral Sönmezoğlu, Gülderen Yanıkkaya Demirel, Sema Aktaş, Sinem Özdemir, Helin Serda Özalp, Hasan Atilla Özkan","doi":"10.1111/trf.17990","DOIUrl":"https://doi.org/10.1111/trf.17990","url":null,"abstract":"Background: Peripheral blood-derived hematopoietic stem cells (HSCs) are widely used for various adult stem cell transplants. To obtain sufficient HSCs from healthy volunteer donors during the apheresis process and ensure that the donors are exposed to fewer apheresis-related side effects, calculation methods have been developed for the prediction of processed blood volume or CD34+ count. However, there is no consensus on a formula to predict the volume of blood to be processed or the number of stem cells to be obtained.Objective: This study aimed to estimate the predicted blood volume and CD34+ cell counts using collection efficiency (CE)-based formulas and evaluate their accuracy compared to the actual CD34+ cell counts. It also seeks to identify the factors that affect CE.Methods: Data from 397 healthy, unrelated stem cell donors were retrospectively analyzed. An algorithm using four different CE2 metrics (1st quartile, mean, 3rd quartile, and median) was developed to predict the volume of blood to be processed using the Spectra Optia continuous mononuclear cell collection procedure.Results: When employing the mean CE2 algorithm, the results revealed a strong correlation (r = .894, p < .001) between predicted and actual CD34+ values. The study also identified strong associations between pre-apheresis CD34+, pre-apheresis leukocyte count, the use of two doses of G-CSF, and low CE2.Conclusion: These findings suggest that the mean CE2 algorithm could be a potent, straightforward, and accurate tool for predicting CD34+ stem cell counts in healthy allogeneic stem cell donors and potentially optimizing stem cell collection procedures.","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141996572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to "Patient and specimen identification in a tertiary care pediatric hospital: Barcodes do not scan themselves". 更正 "一家三级儿科医院的病人和样本识别：条形码不会自动扫描

IF 2.5 3区医学

Transfusion Pub Date : 2024-08-16 DOI: 10.1111/trf.17945

引用次数: 0

Identification of a novel c.506A>C variant on the ABO*A1.02 allele in a Chinese individual. 在一名中国人的 ABO*A1.02 等位基因上发现一个新的 c.506A>C 变异。

IF 2.5 3区医学

Transfusion Pub Date : 2024-08-16 DOI: 10.1111/trf.17991

Yongkui Kong, Ming Shao, Huifang Jin, Qiankun Yang, Xianping Lyu

引用次数: 0

Simple formula for adjusted performance parameters in evaluation of diagnostic methods. 诊断方法评估中调整性能参数的简单公式。

IF 2.5 3区医学

Transfusion Pub Date : 2024-08-15 DOI: 10.1111/trf.17989

Frederik Banch Clausen, Alberte Aspaas Lundquist, Emil Urhammer, Leif Kofoed Nielsen, Klaus Rieneck

引用次数: 0

Iron deficiency-related symptoms in non-anemic whole blood donors. 非贫血全血献血者中与缺铁有关的症状。

IF 2.5 3区医学

Transfusion Pub Date : 2024-08-14 DOI: 10.1111/trf.17983

J Karregat, A Meulenbeld, J Abubakar, F A Quee, K van den Hurk

{"title":"Iron deficiency-related symptoms in non-anemic whole blood donors.","authors":"J Karregat, A Meulenbeld, J Abubakar, F A Quee, K van den Hurk","doi":"10.1111/trf.17983","DOIUrl":"https://doi.org/10.1111/trf.17983","url":null,"abstract":"Introduction: Whole blood donors are at increased risk for iron deficiency (ID). ID anemia is associated with several symptoms, such as fatigue, cognitive dysfunction, pica, and restless leg syndrome (RLS). However, it is unclear if these symptoms also occur when a donor has developed ID without anemia. This study aims to determine whether non-anemic ID (NAID) is associated with the occurrence of ID-related symptoms.Study designs and methods: We combined data from three studies in whole blood donors (i.e., Donor Insight-III, FIND'EM, and FORTE) to create a substantial sample size (N = 12,143). The self-reported occurrence and severity of ID-related symptoms, such as physical and mental health, fatigue, cognitive functioning, pica, and RLS, was measured using validated questionnaires. Associations were studied using logistic regression modeling with ID-related symptoms derived from the questionnaires as the dependent variable and ferritin level group (0-15 μg/L, 15-30 μg/L, and >30 μg/L) as explanatory variable.Results: After applying inclusion and exclusion criteria, 9829 donors were eligible for analysis. In the models corrected for age, body mass index, Hb level, and cohort, only fatigue was shown to be associated with ferritin levels in men, showing lower odds (OR 1.41, 95% CI 1.11-1.79) for fatigue with higher ferritin levels.Conclusion: In these studies, NAID was only associated with self-reported fatigue in male donors. Although selection bias may have led to underestimated associations, ferritin measurements in donors should be primarily considered as a measure to prevent anemia, rather than to prevent or mitigate NAID-related symptoms.","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Keep ahead: A monthly roundup of key articles in other journals 保持领先：每月综述其他期刊的重要文章

IF 2.9 3区医学

Transfusion Pub Date : 2024-08-14 DOI: 10.1111/trf.17982

Caitlin McOmish

引用次数: 0

When transfusion causes a splitting headache: A case report and rapid review of transfusion-associated reversible cerebral vasoconstriction syndrome. 当输血导致头痛欲裂时：输血相关可逆性脑血管收缩综合征的病例报告和快速回顾。

IF 2.5 3区医学

Transfusion Pub Date : 2024-08-14 DOI: 10.1111/trf.17984

Bobbie Pelham-Webb, Yin Guo, Alejandra Ramirez, Evan Waldron, Valentina Emmanuele, Wendy Vargas, Justine Kahn, Elizabeth F Stone

引用次数: 0

Use of group a thawed plasma in emergency transfusions at a pediatric quaternary care center. 在一家儿科四级护理中心的紧急输血中使用 a 组解冻血浆。

IF 2.5 3区医学

Transfusion Pub Date : 2024-08-13 DOI: 10.1111/trf.17985

Cyril Jacquot, Tahirah Jones, Burak Bahar, Julia Cabacar, Jennifer Webb, Yunchuan Delores Mo, Antoine Tavares da Souza, Meghan Delaney

{"title":"Use of group a thawed plasma in emergency transfusions at a pediatric quaternary care center.","authors":"Cyril Jacquot, Tahirah Jones, Burak Bahar, Julia Cabacar, Jennifer Webb, Yunchuan Delores Mo, Antoine Tavares da Souza, Meghan Delaney","doi":"10.1111/trf.17985","DOIUrl":"https://doi.org/10.1111/trf.17985","url":null,"abstract":"Background: Balanced plasma/red blood cell transfusions have shown survival benefit in emergency scenarios. To improve plasma availability, we implemented 5-day group A thawed plasma at our pediatric hospital in February 2021.Study design and methods: We maintain thawed group A plasma units (5-day shelf-life) ready for immediate issue in the blood bank (since February 2021) and trauma code room (since August 2022). Group A plasma (un-titered) is issued for patients with unknown blood type during emergencies. We retrospectively reviewed records and laboratory results of recipients to assess safety and identify possible adverse events related to incompatible plasma.Results: Between February 2021 and December 2023, 173 emergency plasma requests occurred for 161 patients. Ninety-one occurred with massive transfusion protocol activations. Thirty-six patients (22.4%) were blood group B or AB, and 23 received incompatible plasma (age 0-21.3 years, weight 0.74-149.8 kg, incompatible plasma dose 4.0-428.4 mL/kg). These patients did not have any differences in survival outcomes or hospital lengths of stay (LOS) compared with compatible plasma recipients, mirroring the adult experience. None experienced adverse events related to group A plasma. No transfusion reactions were reported. No increase in wastage/outdate occurred upon thawed plasma implementation (2020 versus 2021 to 2023, 7.73% [133/1721] vs. 8.58% [497/5792], p = .284).Conclusions: We implemented 5-day group A thawed plasma. Units are rapidly available from the blood bank and trauma code room without increased wastage. We did not identify any transfusion-associated adverse events in pediatric recipients of incompatible group A plasma.","PeriodicalId":23266,"journal":{"name":"Transfusion","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2024-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141976731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0