Transactions of The Royal Society of Tropical Medicine and Hygiene最新文献_第9页

Evaluating the sensitivity and specificity of Determine™ HIV-1/2 rapid test using a 0.01M phosphate-buffered saline produced at the Medical Research Council Unit The Gambia for the diagnosis of HIV. 评估Determine的敏感性和特异性™ 使用冈比亚医学研究委员会单位生产的0.01M磷酸盐缓冲盐水进行HIV-1/2快速检测，用于诊断HIV。

IF 2.2 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2024-02-01 DOI: 10.1093/trstmh/trad071

Anna Boté-Casamitjana, Tisbeh Faye-Joof, Ousman Bah, Sira Jallow, Alagie Camara, Olimatou Jallow, Nuredin Mohammed, Karen Forrest, Behzad Nadjm

{"title":"Evaluating the sensitivity and specificity of Determine™ HIV-1/2 rapid test using a 0.01M phosphate-buffered saline produced at the Medical Research Council Unit The Gambia for the diagnosis of HIV.","authors":"Anna Boté-Casamitjana, Tisbeh Faye-Joof, Ousman Bah, Sira Jallow, Alagie Camara, Olimatou Jallow, Nuredin Mohammed, Karen Forrest, Behzad Nadjm","doi":"10.1093/trstmh/trad071","DOIUrl":"10.1093/trstmh/trad071","url":null,"abstract":"Background: Human immunodeficiency virus (HIV) rapid diagnostic tests (RDTs) are widely used. However, buffer stockouts commonly lead to utilising non-approved liquids, resulting in errors. Our aim was to evaluate the diagnostic accuracy of an alternative buffer.Methods: Paired Determine HIV-1/2 rapid tests with commercial buffer and locally produced 0.01M phosphate-buffered saline (PBS) were performed on consecutive consenting individuals requiring HIV testing. Serum samples were sent for confirmation through the local gold-standard algorithm (Murex HIV Ag/Ab, Hexagon HIV with/without Geenius HIV 1/2). Test accuracy, κ and exact McNemar's test were also carried out.Results: Of 167 participants, 137 had confirmatory testing. The sensitivity of the Determine HIV-1/2 test using PBS compared with the gold standard was 100% (95% confidence interval [CI] 90.5 to 100) with a specificity of 98% (95% CI 92.9 to 99.8). The κ value was 0.94 compared with the gold standard and 0.92 compared with the Determine HIV-1/2 test using the commercial buffer. McNemar's test showed no evidence of differing sensitivities. Due to operational constraints, the study included 37 of the 49 positive cases as determined by the sample size calculation, resulting in an attained power of 80% instead of the intended 90%.Conclusions: These results suggest that 0.01M PBS is an alternative solution for Determine HIV-1/2 when buffer stockouts occur.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10833640/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41213997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

No secondary impact of ivermectin mass drug administration for onchocerciasis elimination on the prevalence of scabies in northwestern Ethiopia. 为消除盘尾丝虫病而大量施用伊维菌素不会对埃塞俄比亚西北部的疥疮发病率产生二次影响。

IF 2.2 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2024-02-01 DOI: 10.1093/trstmh/trad061

Robel Yirgu, Jo Middleton, Abebaw Fekadu, Gail Davey, Stephen Bremner, Christopher Iain Jones, Jackie A Cassell

{"title":"No secondary impact of ivermectin mass drug administration for onchocerciasis elimination on the prevalence of scabies in northwestern Ethiopia.","authors":"Robel Yirgu, Jo Middleton, Abebaw Fekadu, Gail Davey, Stephen Bremner, Christopher Iain Jones, Jackie A Cassell","doi":"10.1093/trstmh/trad061","DOIUrl":"10.1093/trstmh/trad061","url":null,"abstract":"Background: Mass drug administration (MDA) is among the five major strategies that are currently in use to control, eliminate or eradicate Neglected Tropical Diseases (NTDs). Optimising MDA to control multiple NTDs maximises impact. The objective of this study is to estimate the secondary impact of ivermectin MDA for onchocerciasis on the prevalence of scabies.Methods: This quasi-experimental study was conducted in Ayu Guagusa district, northwestern Ethiopia. Scabies prevalence was estimated in surveys before the MDA, at 6 and 12 months afterwards. The sample size was 1437 people from a panel of 381 randomly selected study households. Multistage sampling was employed in randomly selecting six kebeles (the lowest administrative unit) with respective gotes (small villages) and households. All members of the selected households were invited to participate in the study and participants who were available in all three surveys formed a cohort.Results: Scabies prevalence was similar prior to the MDA (13.4%, 95% CI 11.7 to 15.2%) and 6 months after (11.7%, 95% CI 10.1 to 13.2%) but was substantially greater at 12 months (22.1%, 95% CI 20.1 to 24.1%). The 6-month incidence and disappearance rates were 10.8% (95% CI 8.8 to 13.2%) and 82.6% (95% CI 75.0 to 88.6%), respectively.Conclusions: Ivermectin MDA for onchocerciasis was not observed to have a secondary impact on the prevalence of scabies over the follow-up period of 12 months.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10152961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molecular detection of dengue and chikungunya viruses in surveillance of wild-caught Aedes mosquitoes in Punjab, North India. 在印度北部旁遮普省对野生伊蚊的监测中进行登革热和基孔肯雅病毒的分子检测。

IF 2.2 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2024-02-01 DOI: 10.1093/trstmh/trad054

Taruna Kaura, Subhabrata Sarkar, Vikrant Sharma, Abhishek Mewara, Seema Devi, NazatInder Singh, Kanwalpreet Kaur, Rakesh Sehgal, R K Ratho, Gagandeep Singh Grover

{"title":"Molecular detection of dengue and chikungunya viruses in surveillance of wild-caught Aedes mosquitoes in Punjab, North India.","authors":"Taruna Kaura, Subhabrata Sarkar, Vikrant Sharma, Abhishek Mewara, Seema Devi, NazatInder Singh, Kanwalpreet Kaur, Rakesh Sehgal, R K Ratho, Gagandeep Singh Grover","doi":"10.1093/trstmh/trad054","DOIUrl":"10.1093/trstmh/trad054","url":null,"abstract":"Background: Dengue (DENV), Zika (ZIKV) and chikungunya (CHIKV) viruses are transmitted mainly by Aedes mosquitoes and are responsible for a significant global healthcare burden. The current study aimed to detect arboviruses in the Aedes mosquitoes in close proximity of patients during the transmission season.Methods: Both immature and adult mosquitoes were collected from in and around the patients' houses. Mosquito pools were homogenized and extracted RNA was subjected to reverse transcription polymerase chain reaction for arboviral detection. Transovarian transmission (TOT) was assessed by screening F0 adults. Mosquito positivity was correlated with the aetiological agents identified in patients.Results: Of 46 pools, 19 consisted of wild Aedes, with arboviral positivity in 53% (10/19) of pools. Among wild A. aegypti pools, positivity of DENV mono-infection, CHIKV mono-infection and DENV+CHIKV co-infection was noted in four, two and three pools, respectively. One wild pool of Aedes albopictus was positive for DENV-1. Similarly, A. aegypti F0 (adult Aedes developed from immatures) pools showed 59.2% (16/27) positivity for arboviruses. F0 Aedes showed positivity in three, six and seven pools for DENV-2, CHIKV and DENV+CHIKV, respectively, suggestive of TOT. DENV serotypes and CHIKV from 24 patients' serum samples were matched with strains isolated from Aedes and correlation was observed in four instances.Conclusions: The study detected DENV and CHIKV from wild-caught Aedes and found evidence of DENV and CHIKV TOT in F0 adults.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10396736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seroepidemiology of Toxoplasma gondii infection in blood donors in a population from the northwestern region of São Paulo state, Brazil. 巴西圣保罗州西北部地区献血者感染弓形虫的血清流行病学。

IF 2.2 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2024-02-01 DOI: 10.1093/trstmh/trad060

Letícia Carolina Paraboli Assoni, Fabiana Nakashima, Valquíria Pardo de Sousa, Natália Juliana Paduan, Isabela Rufino Andreasse, Thelma Helena Anghinoni, Geraldo Magela de Faria Junior, Octávio Ricci Junior, Lilian Castiglioni, Cinara Cássia Brandão, Luiz Carlos de Mattos, Christiane Maria Ayo

{"title":"Seroepidemiology of Toxoplasma gondii infection in blood donors in a population from the northwestern region of São Paulo state, Brazil.","authors":"Letícia Carolina Paraboli Assoni, Fabiana Nakashima, Valquíria Pardo de Sousa, Natália Juliana Paduan, Isabela Rufino Andreasse, Thelma Helena Anghinoni, Geraldo Magela de Faria Junior, Octávio Ricci Junior, Lilian Castiglioni, Cinara Cássia Brandão, Luiz Carlos de Mattos, Christiane Maria Ayo","doi":"10.1093/trstmh/trad060","DOIUrl":"10.1093/trstmh/trad060","url":null,"abstract":"Background: Toxoplasmosis is one of the most common parasitic infections worldwide with varying prevalence between human populations. These variations are mainly associated with human exposure to risk factors. In this article, the seroprevalence of Toxoplasma gondii infection and the risk factors associated with infection in 1729 blood donors from São José do Rio Preto, São Paulo, Brazil were analysed.Methods: The serological tests for detecting immunoglobulin M (IgM) and immunoglobulin G (IgG) anti-T. gondii were used. The risk factors associated with the infection were identified through the application of an epidemiological questionnaire.Results: The prevalence of T. gondii infection was 48.0%. The following factors were identified in the final model after multiple logistic regression analysis: drinking raw milk (p=0.003; odds ratio [OR] 1.364 [confidence interval {CI} 1.1 to 1.7]), residing in a rural area (p<0.0001; OR 2.764 [CI 1.7 to 4.6]) and receiving a blood transfusion (p=0.015; OR 1.856 [CI 1.1 to 3.0]).Conclusions: The data obtained in this study showed that the blood donor population is exposed to risk factors related to infection by T. gondii. These data allow the establishment of control programs to contribute to public health in northwestern São Paulo state.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10176450","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to: Case report: recurrence of Plasmodium vivax malaria due to defective cytochrome P450 2D6 function in Pos Lenjang, Pahang, Malaysia. 更正：病例报告：马来西亚彭亨Pos Lenjang因细胞色素P450 2D6功能缺陷导致间日疟原虫疟疾复发。

IF 2.2 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2024-02-01 DOI: 10.1093/trstmh/trad076

引用次数: 0

Snakebites epidemiology in Mexico: a 13-year ecological analysis. 墨西哥的蛇咬伤流行病学：13年的生态学分析。

IF 2.2 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2024-02-01 DOI: 10.1093/trstmh/trad070

Ricardo Méndez-Molina, Ailed Karola Villela-Oriza, Andrea Ariadne Espinosa-Couoh, Oswaldo Huchim-Lara

{"title":"Snakebites epidemiology in Mexico: a 13-year ecological analysis.","authors":"Ricardo Méndez-Molina, Ailed Karola Villela-Oriza, Andrea Ariadne Espinosa-Couoh, Oswaldo Huchim-Lara","doi":"10.1093/trstmh/trad070","DOIUrl":"10.1093/trstmh/trad070","url":null,"abstract":"Background: Globally, snakebites have a significant impact on public health and represent substantial costs for health services. Their severity is particularly relevant in developing countries due to the lack of resources and accessibility to health facilities. Additionally, the number of cases may be underestimated, highlighting the urgent need for improved prevention measures.Methods: An observational ecological study was undertaken using the records identified with X200-X209 codes registered in the Ministry of Health injuries database during 2010-2022. Variables included information related to the patient, the snakebite and the healthcare provided. Statistical analysis was carried out with STATA 16 and Microsoft Excel 2020.Results: A total of 10 420 snakebites were registered. The average number of cases per year was 788 (IQR 615, 875) and 82.74% occurred during the rainy season. The median age was 35 (IQR 19, 52) y and early adulthood was the most affected age group; bites were most common on the hand and in the living place. The Eastern region of Mexico registered the highest number of cases, with 3496 (33.71%) of snakebites. The lethality rate was 18.23 per 10 000.Conclusions: Snakebites are a significant health problem in Mexico. Most injuries occur among men in early adulthood, in households and in the upper extremities.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41152358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of acute kidney injury among dengue cases: a systematic review and meta-analysis. 登革热病例中急性肾损伤的发生率：系统回顾和荟萃分析。

IF 2.2 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2024-01-02 DOI: 10.1093/trstmh/trad067

Ganesh Bushi, Muhammed Shabil, Bijaya Kumar Padhi, Mohammed Ahmed, Pratima Pandey, Prakasini Satapathy, Sarvesh Rustagi, Keerti Bhusan Pradhan, Zahraa Haleem Al-Qaim, Ranjit Sah

{"title":"Prevalence of acute kidney injury among dengue cases: a systematic review and meta-analysis.","authors":"Ganesh Bushi, Muhammed Shabil, Bijaya Kumar Padhi, Mohammed Ahmed, Pratima Pandey, Prakasini Satapathy, Sarvesh Rustagi, Keerti Bhusan Pradhan, Zahraa Haleem Al-Qaim, Ranjit Sah","doi":"10.1093/trstmh/trad067","DOIUrl":"10.1093/trstmh/trad067","url":null,"abstract":"Numerous studies have shown a correlation between dengue virus (DENV) infection and kidney disease. However, there is no existing meta-analysis on the prevalence of kidney diseases in the dengue population. A thorough systematic review and meta-analysis were undertaken to determine the prevalence of renal problems in people with DENV infection in order to fill this knowledge gap. A rigorous electronic literature search was carried out up to 25 January 2023 in a number of databases, including ProQuest, EBSCOhost, Scopus, PubMed and Web of Science. The search aimed to find articles that reported on the prevalence of kidney diseases in patients with DENV infection. Using the modified Newcastle-Ottawa Scale, the quality of the included studies was assessed. The meta-analysis included a total of 37 studies with 21 764 participants reporting on the prevalence of acute kidney injury (AKI) in individuals with DENV infection. The pooled prevalence of AKI in dengue patients was found to be 8% (95% confidence interval 6 to 11), with high heterogeneity across studies. The studies included are of moderate quality. The study revealed a high AKI prevalence in dengue patients, underlining the need for regular renal examination to detect AKI early and reduce hospitalization risk. Further research is needed to understand the dengue-kidney relationship and develop effective management strategies.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10572626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seroprevalence and risk factors for Toxoplasma gondii infection among pregnant women at Debre Markos Referral Hospital, northwest Ethiopia. 埃塞俄比亚西北部 Debre Markos 转诊医院孕妇感染弓形虫的血清流行率和风险因素。

IF 2.2 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2024-01-02 DOI: 10.1093/trstmh/trad053

Enirsie Kassie, Nigatu Kebede, Tesfu Kassa, Abebe Garoma, Musse Girma, Yewbnesh Asnake, Ayinalem Alemu, Sileshi Degu, Meshesha Tsigie

{"title":"Seroprevalence and risk factors for Toxoplasma gondii infection among pregnant women at Debre Markos Referral Hospital, northwest Ethiopia.","authors":"Enirsie Kassie, Nigatu Kebede, Tesfu Kassa, Abebe Garoma, Musse Girma, Yewbnesh Asnake, Ayinalem Alemu, Sileshi Degu, Meshesha Tsigie","doi":"10.1093/trstmh/trad053","DOIUrl":"10.1093/trstmh/trad053","url":null,"abstract":"Background: To assess the seroprevalence and risk factors of Toxoplasma gondii infection in pregnant women at the Debre Markos Referral Hospital, northwest Ethiopia.Methods: A facility-based cross-sectional study was undertaken among pregnant women from March 2020 to May 2021. Sociodemographic and clinical data were collected from randomly selected participants. Five millilitres of blood was collected and an enzyme-linked immunosorbent assay kit was used to test for T. gondii immunoglobulin G (IgG) antibodies. A logistic regression model was computed to identify the risk factors. The adjusted odds ratio (aOR) was estimated along with the 95% confidence interval (CI). A statistically significant association was defined as p<0.05.Results: T. gondii IgG antibody positivity was found in 38.8% (n=132) of 340 pregnant women. Contact with cats (AOR 2.5 [95% CI 1.5 to 4.2]), eating raw/undercooked meat (AOR 5.7 [95% CI 3.2 to 10.3]), consuming unwashed vegetables (AOR 4.1 [95% CI 2.1 to 8.0]), a history of abortion (AOR 1.9 [95% CI 1.1 to 3.3]) and drinking water sources (AOR 2.5 [95% CI 1.2 to 5.2]) demonstrated a statistically significant association with T. gondii infection.Conclusions: Toxoplasmosis was found to be fairly common in pregnant mothers. Proper cat excreta disposal, not eating raw/undercooked meat, maintaining hand cleanliness and following environmental sanitation protocols could be important to decrease T. gondii infection.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9970747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Knowledge and perception of asymptomatic malaria in the Volta region of Ghana. 加纳沃尔特地区对无症状疟疾的认识和看法。

IF 2.2 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2024-01-02 DOI: 10.1093/trstmh/trad049

Verner N Orish, Caleb Kyeremateng, Baffoe P Appiah, Isaac B Addei, Moses A Ayaba, Precious K Kwadzokpui, Aleksandra Marinkovic, Stephanie Prakash, Chuku Okorie, Ricardo Izurieta, Adekunle Sanyaolu

{"title":"Knowledge and perception of asymptomatic malaria in the Volta region of Ghana.","authors":"Verner N Orish, Caleb Kyeremateng, Baffoe P Appiah, Isaac B Addei, Moses A Ayaba, Precious K Kwadzokpui, Aleksandra Marinkovic, Stephanie Prakash, Chuku Okorie, Ricardo Izurieta, Adekunle Sanyaolu","doi":"10.1093/trstmh/trad049","DOIUrl":"10.1093/trstmh/trad049","url":null,"abstract":"Background: The control of asymptomatic malaria is considered a key aspect of malaria control. This study aimed to assess the knowledge and perception of asymptomatic malaria among people in Ho municipality of the Volta region.Methods: A descriptive cross-sectional study involving questionnaire administration was conducted among randomly sampled residents of the Ho municipality of the Volta region of Ghana. Using SPSS version 25 statistical software, frequency distributions and proportions were computed for sociodemographic variables while knowledge and perception about asymptomatic malaria were computed into percentages and categorized into three levels based on Bloom's cut-off for further analysis. Findings with p-values <0.05 were considered statistically significant.Results: Among the 200 participants, 197 (98.5%) were aware of malaria. The majority (116 [58.0%]) of the study participants agreed to the possibility of asymptomatic infection, but most (133 [66.5%]) of the community members did not know that asymptomatic individuals can still transmit infections. The majority of the participants (184 [92.0%]) showed interest in getting further education on asymptomatic malaria and a significant majority (180 [90.0%]) expressed a willingness to take treatment after testing positive without showing any symptoms.Conclusions: Asymptomatic malaria control can be achieved through a mass testing and treatment strategy, therefore improving the knowledge and perception about asymptomatic malaria might improve malaria control.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10302451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of the availability, effectiveness and equity of deployment of resources in the health system response to COVID-19 in Nigeria. 分析尼日利亚卫生系统应对 COVID-19 的资源部署的可用性、有效性和公平性。

IF 2.2 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2024-01-02 DOI: 10.1093/trstmh/trad043

Nwadiuto C Ojielo, Nkolika P Uguru, Chinyere C Okeke, Obinna E Onwujekwe

{"title":"Analysis of the availability, effectiveness and equity of deployment of resources in the health system response to COVID-19 in Nigeria.","authors":"Nwadiuto C Ojielo, Nkolika P Uguru, Chinyere C Okeke, Obinna E Onwujekwe","doi":"10.1093/trstmh/trad043","DOIUrl":"10.1093/trstmh/trad043","url":null,"abstract":"Background: Coronavirus disease 2019 (COVID-19) exposed weaknesses in the health systems of countries such as Nigeria, which affected the effectiveness of the health system response to the pandemic. This paper provides new knowledge on the level of the availability, effectiveness and equity of resources in response to COVID-19 in Nigeria. This is valuable information for improving the delivery of countermeasures against future pandemics.Methods: The study was conducted at the federal level and in two states in Nigeria. The states were Lagos in the southwest and Enugu in the southeast. In-depth interviews were undertaken with 34 key informants. NVivo version 12 software was used for coding and thematic analysis.Results: There were inadequate, inequitable and suboptimal resources (human, financial, equipment and materials) for the response. In some of the countermeasures, only people that were employed in the formal sector benefitted from the distribution of welfare materials and financial packages; the informal sector, which constitutes the majority of the poor population in Nigeria, was excluded.Conclusions: Inequity and suboptimal availability of resources to control COVID-19 led to reduced effectiveness of the health system response to the disease in Nigeria. Such negative factors must be mitigated in future responses to pandemics in the country.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":null,"pages":null},"PeriodicalIF":2.2,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9906927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0