Transactions of The Royal Society of Tropical Medicine and Hygiene最新文献_第9页

Adjunctive nivolumab in combination with antibiotic therapy for the management of refractory melioidosis in a patient with metastatic breast cancer and chemotherapy-induced pancytopenia. 辅助纳沃单抗联合抗生素治疗转移性乳腺癌和化疗引起的全细胞减少症患者的难治性类鼻疽。

IF 1.9 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-01-06 DOI: 10.1093/trstmh/trae142

Praveen Kumar Tirlangi, Swathi Kiran, Vandana Ke, C Mukhopadhyay, Ramit Kundu, Ananth Pai, Priya Ps, Kavitha Saravu

引用次数: 0

Utilising snake rescue data to understand snake-human conflict in Hooghly, West Bengal, India. 利用蛇救援数据来了解印度西孟加拉邦胡格利的蛇与人的冲突。

IF 1.9 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-01-03 DOI: 10.1093/trstmh/trae124

Sourish Kuttalam, John Benjamin Owens, Vishal Santra, Molla T Ahmed, Biswajit Das, Surojit Das, Ayan Koley, Rakesh Koley, Axel Barlow, Anita Malhotra

{"title":"Utilising snake rescue data to understand snake-human conflict in Hooghly, West Bengal, India.","authors":"Sourish Kuttalam, John Benjamin Owens, Vishal Santra, Molla T Ahmed, Biswajit Das, Surojit Das, Ayan Koley, Rakesh Koley, Axel Barlow, Anita Malhotra","doi":"10.1093/trstmh/trae124","DOIUrl":"https://doi.org/10.1093/trstmh/trae124","url":null,"abstract":"Background: Snakebite envenoming, classified as a neglected tropical disease, poses a significant threat to life in India, where it is estimated to cause 58 000 fatalities as well as 140 000 morbidities annually. To reduce the occurrence of snakebite, we need a comprehensive understanding of human-snake conflict ecology. Snake rescue networks represent a vital resource for gathering such ecological data.Methods: In this study, we utilised snake rescue data from 520 rescue encounters carried out by a local rescue network in Hooghly, West Bengal, from July 2020 to October 2022, to investigate patterns of human-snake conflict and the influence of climatic factors on these patterns.Results: The spectacled cobra Naja naja was the most encountered of the five venomous species involved in 365 rescues. Our analysis revealed a significant correlation between rescue location and venomous/non-venomous encounters, with non-venomous encounters being more prevalent inside built-up locations. Rainfall on the previous day significantly increased encounters and influenced the species involved, while daily minimum temperature also influenced encounters with venomous species. We also found that both Bungarus (krait) species present were mostly encountered between 18:00 h and midnight.Conclusions: This study highlights the multifaceted factors influencing human-snake conflicts in the region, including seasonality, geographic location, rainfall patterns, and temperature dynamics. It underscores the potential of snake rescue data as a valuable resource for deepening our understanding of regional variations in snake-human interactions.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Health literacy among the rural Bangladeshi population on first aid measures and prevention of snakebite. 在孟加拉国农村人口中普及急救措施和预防蛇咬伤的卫生知识。

IF 1.9 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-01-03 DOI: 10.1093/trstmh/trae130

Chowdhury Farheen, A K M F Rahman, Aniruddha Ghose, Md R Amin, Abu S M M Rahman, Abdullah A Sayeed, F M A Rahaman, Chinmaya Howlader, Sayra Khan, Rumana Rashid, Nusaer Chowdhury, Geeta R Debi, Md Sahidur Rahman, M A Faiz

{"title":"Health literacy among the rural Bangladeshi population on first aid measures and prevention of snakebite.","authors":"Chowdhury Farheen, A K M F Rahman, Aniruddha Ghose, Md R Amin, Abu S M M Rahman, Abdullah A Sayeed, F M A Rahaman, Chinmaya Howlader, Sayra Khan, Rumana Rashid, Nusaer Chowdhury, Geeta R Debi, Md Sahidur Rahman, M A Faiz","doi":"10.1093/trstmh/trae130","DOIUrl":"https://doi.org/10.1093/trstmh/trae130","url":null,"abstract":"Background: Bangladesh has a high rate of snakebite. In rural areas, there is a significant mortality and morbidity rate due to lack of awareness and inappropriate first aid practices. This study aims to determine the knowledge and practices of the rural population in two subdistricts of Bangladesh regarding snakebite prevention and first aid measures.Methods: This cross-sectional survey is part of an intervention study that was carried out in 250 randomly selected primary sampling units of Shibganj in the Chapainawabganj district and Kalapara in the Patuakhali district of Bangladesh. We enrolled a total of 2954 participants. The practice and knowledge were regarded adequate when the score exceeded 50%. We conducted a binomial logistic regression to identify the factors associated with inadequate knowledge and practice.Results: The community's knowledge (15.9%) and practice (14.5%) regarding snakebite prevention was insufficient. More than 77% and 45.4% of respondents believed that applying a tourniquet above the bite site and seeking a traditional healer after a snakebite were effective first aid measures. Poor knowledge was more likely to occur in farming, fishing, homemaker groups and those with lower incomes (11 000-24 000 Bangladeshi taka). Negative practices were associated with females and high family income.Conclusions: This study highlights the necessity of community intervention, with a focus on appropriate first aid and prevention measures through widespread education.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Conflict between sea snakes and humans on the coast of West Bengal and Odisha, India: perception, attitudes and incidents. 印度西孟加拉邦和奥里萨邦海岸海蛇与人类之间的冲突：感知、态度和事件。

IF 1.9 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-01-03 DOI: 10.1093/trstmh/trae086

Anweshan Patra, Ardhendu Das Mahapatra, Anita Malhotra, Vishal Santra, Sudipta Kumar Ghorai, D Annadurai

{"title":"Conflict between sea snakes and humans on the coast of West Bengal and Odisha, India: perception, attitudes and incidents.","authors":"Anweshan Patra, Ardhendu Das Mahapatra, Anita Malhotra, Vishal Santra, Sudipta Kumar Ghorai, D Annadurai","doi":"10.1093/trstmh/trae086","DOIUrl":"https://doi.org/10.1093/trstmh/trae086","url":null,"abstract":"Background: Snakebite envenoming is a critical medical emergency and significant global public health issue, with India experiencing the highest annual snakebite deaths. Sea snakes in the Indian Ocean pose a severe threat to rural fishermen due to their potent neurotoxins.Methods: From December 2020 to December 2021, we conducted surveys at 15 fishing ports in East Medinipur, West Bengal, and Balasore, Odisha, India (between 21.805651 N 87.874188 E and 21.574851 N 87.374059 E). We interviewed 2301 fishermen in 421 group sessions to document sea snake bite incidents, outcomes and perceptions from 2012 onwards. Historical data were also retrieved from various databases and social media platforms.Results: We recorded 166 sea snake bite cases, with 55.4% fatalities, 2.4% permanent disabilities and 41% survivors. Gill net fishermen were the most affected, with most bites occurring while handling snakes caught in nets, particularly at dawn and dusk. Fishermen reported a significant decline in sea snake populations over the past decade due to by-catch and killing practices.Conclusions: Sea snake bites are a major occupational hazard for Indian fishermen, with high fatality rates due to limited medical access. Increased awareness, safer handling practices and improved medical infrastructure are essential to reduce mortality and conserve sea snake populations. This study highlights the need for targeted interventions in affected communities.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Challenges of researching snakes in India. 在印度研究蛇的挑战。

IF 1.9 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-01-03 DOI: 10.1093/trstmh/trae104

Sourish Kuttalam, Anita Malhotra

引用次数: 0

Treatment and treatment outcomes of snakebite envenoming in Uganda: a retrospective analysis. 乌干达蛇咬伤的治疗和治疗结果：回顾性分析。

IF 1.9 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-01-03 DOI: 10.1093/trstmh/trae112

Stella Maris Nanyonga, Scott Kaba Matafwali, Denis Kibira, Freddy Eric Kitutu

{"title":"Treatment and treatment outcomes of snakebite envenoming in Uganda: a retrospective analysis.","authors":"Stella Maris Nanyonga, Scott Kaba Matafwali, Denis Kibira, Freddy Eric Kitutu","doi":"10.1093/trstmh/trae112","DOIUrl":"https://doi.org/10.1093/trstmh/trae112","url":null,"abstract":"Background: Snakebite envenoming is a neglected tropical disease that causes significant morbidity and mortality in rural sub-Saharan Africa. However, there is a notable lack of data concerning the management and treatment outcomes for those affected. This study addresses this gap by examining the management and treatment outcomes of snakebite victims in Uganda.Methods: We reviewed retrospective data of 532 snakebite cases attending 16 Ugandan health facilities from January 2017 to December 2021. Demographic characteristics and clinical data were extracted from patient records and summarized using descriptive statistics.Results: The snakebite victims had a median age of 26 y, most were male (55.3%) and had bites of unidentified snake species (92.3%). Among the 465 treated patients, 71.6% received antibiotics, 66.0% hydrocortisone, 36.3% analgesics and only 6.9% antivenom. No adverse antivenom reactions were documented. The majority (89.5%) were discharged; 1.3% died and 5.5% had unknown outcomes.Conclusions: These results suggest that snakebite envenoming affects vulnerable Ugandans, particularly young males and children. Treatment is primarily supportive, with antibiotic overuse and infrequent antivenom administration. Health provider training on appropriate snakebite management is needed to optimize outcomes.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The incidence of snakebite in South Africa and the challenges associated with lack of reporting. 南非蛇咬伤的发生率以及与缺乏报告相关的挑战。

IF 1.9 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-01-03 DOI: 10.1093/trstmh/trae109

Hiral Naik, Graham J Alexander

{"title":"The incidence of snakebite in South Africa and the challenges associated with lack of reporting.","authors":"Hiral Naik, Graham J Alexander","doi":"10.1093/trstmh/trae109","DOIUrl":"https://doi.org/10.1093/trstmh/trae109","url":null,"abstract":"Background: Snakebite is a public health challenge that has a substantial impact on humans and snakes. Annually, millions of people are affected by snakebite globally but there is a paucity of detailed data on snakebite incidences. The aim of this study was to assess the patterns of snakebite incidences in South Africa.Methods: We collected data from hospital records, information from the National Snakebite Database and records from the AfriTox Telelog database from 2011 to 2024.Results: The combined dataset showed that 3496 snakebite incidences have been recorded over 12.5 years. The prevalence was calculated to be 5.63 per 100 000 individuals of the population for South Africa, with the highest prevalence in KwaZulu-Natal (8.89). Males made up 65.9% of snakebite incidences and most incidences were recorded between November and March. The snake species responsible for most snakebite incidences was Bitis arietans.Conclusion: Snakebite is generally well managed in South Africa with few recorded deaths despite the relatively high number of bites. However, incidents are often not recorded or have missing information particularly regarding the circumstances of the bite. Our study provides insight on the snake species responsible for snakebite incidences in South Africa and can be used to create prevention measures.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Freshwater jellyfish in northeastern Argentina: a risk to human health. 阿根廷东北部的淡水水母：对人类健康的威胁。

IF 1.9 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-01-03 DOI: 10.1093/trstmh/trae067

Milena Gisela Casafús, Micaela Andrea Gritti, Cecilia Miranda, Paula Guimarães, Luciana Montalto, María Elisa Peichoto

{"title":"Freshwater jellyfish in northeastern Argentina: a risk to human health.","authors":"Milena Gisela Casafús, Micaela Andrea Gritti, Cecilia Miranda, Paula Guimarães, Luciana Montalto, María Elisa Peichoto","doi":"10.1093/trstmh/trae067","DOIUrl":"10.1093/trstmh/trae067","url":null,"abstract":"Background: Although cnidarians are mostly marine organisms, the occurrence of freshwater jellyfish frequently arouses the interest of ecologists, due to their sudden and unusual appearances in natural and artificial water bodies around the world.Methods: This study describes a series of cases compatible with cnidarian envenomation that occurred coincidentally in time and space with the presence of Craspedacusta sowerbii Lankester, 1880 jellyfish in the province of Misiones (El Saltito stream) in January 2022. A year later, its presence was confirmed in another watercourse of this province (Cazador stream). Based on these findings, its possible toxicological consequences in humans were evaluated by characterizing the jellyfish extract using sodium dodecyl sulfate-polyacrylamide gel electrophoresis and enzymatic/toxic activities.Results: We revealed the presence of proteolytic enzymes and cytolytic toxin(s), which-by means of activating the inflammatory cascade-could explain the stinging skin lesions observed in the suspected cases described.Conclusions: In addition to recording for the first time the occurrence of this cnidarian in northeastern Argentina, this work provides, for the first time, a toxinological explanation for the clinical observations after contact with the most widespread freshwater jellyfish species in the world, giving support to health professionals in the diagnosis and management of such accidents/envenomation.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":"48-57"},"PeriodicalIF":1.9,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142547650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Emerging and re-emerging viral exanthems among children: what a physician should know. 儿童中新出现和再次出现的病毒性外感：医生须知。

IF 1.9 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-01-03 DOI: 10.1093/trstmh/trae087

Anuradha Bishnoi, Apoorva Sharma, Hitaishi Mehta, Keshavamurthy Vinay

{"title":"Emerging and re-emerging viral exanthems among children: what a physician should know.","authors":"Anuradha Bishnoi, Apoorva Sharma, Hitaishi Mehta, Keshavamurthy Vinay","doi":"10.1093/trstmh/trae087","DOIUrl":"10.1093/trstmh/trae087","url":null,"abstract":"Viral exanthems can present with diverse morphologies of rash, including macular, maculopapular, papular, urticarial and vesicular, or sometimes a combination of these. There has been an increasing trend towards emerging and re-emerging viral exanthems in recent years, the cause of which is multifactorial, including changing environmental conditions and altered host-vector-agent interaction. The significant temperature variations brought on by climate change and ever-increasing international travel has modified the host-agent interactions, and many re-emerging viral illnesses are now presenting with atypical presentations, including an increased frequency of affliction across broader age groups and heightened manifestations often posing as 'great imitators' mimicking a myriad of other dermatoses. Although final diagnosis often relies on serological and molecular tests, certain cutaneous clues can help arrive at a probable clinical diagnosis and help the clinicians order specific and relevant investigations, especially in resource-poor settings where access to laboratory diagnostic tests is likely to be limited. In this review we explore the changing disease dynamics of common viral infections, especially in resource-poor settings, including coronavirus disease 2019, chikungunya, hand-foot-and-mouth disease and some newly emerging ones like mpox (previously referred to as monkeypox), and highlight recent developments in our understanding of the clinical variations seen in their presentations.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":"13-26"},"PeriodicalIF":1.9,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary health system strengthening and system-level interventions for tackling snakebite envenoming in India. 加强初级卫生系统和处理印度蛇咬伤事件的系统级干预措施。

IF 1.9 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-01-03 DOI: 10.1093/trstmh/trae106

Priyanka Kadam, Stuart Ainsworth, Bhupeshwari Patel

引用次数: 0