Transactions of The Royal Society of Tropical Medicine and Hygiene最新文献_第4页

Clinical outcomes in patients hospitalized due to heart failure with Chagas disease vs other etiologies in the USA. 美国查加斯病与其他病因导致心力衰竭住院患者的临床结果

IF 1.5 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-09-16 DOI: 10.1093/trstmh/traf093

Luis E Echeverría, Lyda Z Rojas, Carolina Duque, Rachel Marcus, Johana Contreras, Sergio A Gómez-Ochoa

{"title":"Clinical outcomes in patients hospitalized due to heart failure with Chagas disease vs other etiologies in the USA.","authors":"Luis E Echeverría, Lyda Z Rojas, Carolina Duque, Rachel Marcus, Johana Contreras, Sergio A Gómez-Ochoa","doi":"10.1093/trstmh/traf093","DOIUrl":"https://doi.org/10.1093/trstmh/traf093","url":null,"abstract":"Background: Chagas disease (CD) affects approximately 300 000 individuals in the USA. However, its impact on heart failure (HF) hospitalizations in the USA as non-endemic setting remains poorly characterized. We aimed to assess the clinical profile and acute clinical outcomes of HF hospitalizations in patients with CD compared with those without CD in the USA.Methods: The National Inpatient Sample (2002-2021) was queried for adult hospitalizations with a primary diagnosis of HF. Multivariable regression models assessed the association between CD diagnosis and in-hospital mortality, length of stay and total healthcare costs.Results: Among 2 990 959 HF hospitalizations, 154 (0.005%) had a CD diagnosis. After adjustment, CD was associated with longer length of stay (β=5.94 d, 95% CI 4.92 to 6.97) and higher total healthcare costs (β=US$94 886, 95% CI 79 282 to 110 490), but not differential mortality (OR=0.63, 95% CI 0.19 to 2.11). Sex-stratified analyses revealed longer hospitalizations in females (β=8.58 vs 3.75 d), but higher healthcare costs in males (β=US$106 667 vs 80 089) with CD compared with their non-CD counterparts.Conclusions: In the USA, HF hospitalizations with CD are characterized by increased healthcare utilization, despite similar mortality compared with non-CD admissions. Sex-specific differences in outcomes highlight the need for targeted approaches to care delivery. Larger studies focused on CD cases detection are needed to have a better understanding of the burden of this neglected disease in non-endemic settings.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spatio-temporal analysis of human visceral leishmaniasis in the Central-West region of Brazil from 2010 to 2019. 2010 - 2019年巴西中西部地区人类内脏利什曼病时空分析

IF 1.5 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-09-16 DOI: 10.1093/trstmh/traf092

Isabela Resende Ávila, Diogo Tavares Cardoso, Francisco Eduardo Almeida-de-Souza, David Soeiro Barbosa, Juliana Maria Trindade Bezerra

{"title":"Spatio-temporal analysis of human visceral leishmaniasis in the Central-West region of Brazil from 2010 to 2019.","authors":"Isabela Resende Ávila, Diogo Tavares Cardoso, Francisco Eduardo Almeida-de-Souza, David Soeiro Barbosa, Juliana Maria Trindade Bezerra","doi":"10.1093/trstmh/traf092","DOIUrl":"https://doi.org/10.1093/trstmh/traf092","url":null,"abstract":"Background: Visceral leishmaniasis (VL) is considered a neglected tropical disease with high lethality. This study aimed to analyze the spatio-temporal dynamics of VL in the Central-West region of Brazil, from 2010 to 2019.Methods: Using data obtained from the Sistema de Informação de Agravos de Notificações (SINAN) from Brazil and spatio-temporal analysis tools, an ecological study of VL cases was carried out considering each federated unit in the Central-West region from 2010 to 2019.Results: It was observed that state of Mato Grosso do Sul had the majority of municipalities with high incidence in all temporal series analyzed. A heterogeneous distribution of VL with spatial clustering in the state of Mato Grosso do Sul was observed. Furthermore, Goiás and Mato Grosso also presented high-risk municipalities, with clusters of higher relative risk (RR) observed from 2013 to 2017 in Goiás and from 2010 to 2013 in Mato Grosso.Conclusions: Therefore, it is observed that the states of Goiás, Mato Grosso and Mato Grosso do Sul need greater attention to support the adoption of effective measures to control VL in the Brazilian Central-West region.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145092596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Increase in Mycoplasma pneumoniae infections in 2024: experience of a tertiary-care hospital from Porto Alegre, Brazil. 2024年肺炎支原体感染增加：巴西阿雷格里港一家三级保健医院的经验

IF 1.5 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-09-16 DOI: 10.1093/trstmh/traf105

Guilherme Geraldo Lovato Sorio, Gabriela Luchiari Tumioto Giannini, Muriel Gorges, Luiza Martinez Perez, Renata Dortzbacher Feil Klafke, Erik Menezes Martins, Letícia Camargo Marinho, Gabriela Pereira Flores, Cristiane Tejada da Silva Kawski, Andressa Braga, Jaysa Pizzi, Beatriz Arns, Alexandre Prehn Zavascki

引用次数: 0

Comment on: Diagnostic sensitivity of formalin-fixed faecal microscopy for the detection of soil-transmitted helminths. 点评：福尔马林固定粪便显微镜检测土壤传播蠕虫的诊断敏感性。

IF 1.5 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-09-16 DOI: 10.1093/trstmh/traf096

Nathkapach Kaewpitoon Rattanapitoon, Schawanya Kaewpitoon Rattanapitoon

引用次数: 0

Clinical presentation and treatment outcomes of patients with mycetoma in Ethiopia: a case series. 埃塞俄比亚足菌肿患者的临床表现和治疗结果：一个病例系列。

IF 1.5 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-09-15 DOI: 10.1093/trstmh/traf098

Wosen Ketema Bedaso, Debisa Eshatu Wendimu, Samira M E Hussein, Ali Awadallah Saeed

引用次数: 0

Social inequalities as effect modifiers of active case-finding strategies for tuberculosis in Brazil: an ecological study. 社会不平等作为巴西结核病积极病例发现策略的影响调节因素：一项生态学研究。

IF 1.5 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-09-08 DOI: 10.1093/trstmh/traf086

José Mário Nunes da Silva, Fredi Alexander Diaz-Quijano

{"title":"Social inequalities as effect modifiers of active case-finding strategies for tuberculosis in Brazil: an ecological study.","authors":"José Mário Nunes da Silva, Fredi Alexander Diaz-Quijano","doi":"10.1093/trstmh/traf086","DOIUrl":"https://doi.org/10.1093/trstmh/traf086","url":null,"abstract":"Background: Social inequalities play a crucial role in the incidence of TB, making it plausible that they act as effect modifiers on the impact of active case-finding (ACF) strategies in the detection of the disease. We estimated the association between ACF strategies and TB detection rates and evaluated their effect modification due to social inequalities in Brazilian municipalities.Methods: We included 5033 municipalities that reported at least one new TB case. We defined the TB detection rate as the outcome variable. Our exposure variables were the proportion of primary care team (PCT) reporting community-based ACF for TB and household contact investigation (HCI) of new TB cases. We also assessed the Municipal Human Development Index (MHDI) and the Social Vulnerability Index (SVI) as potential effect modifier variables.Results: The TB detection rate was positively associated with both the proportion of PCTs conducting community-based ACF and the proportion conducting HCI. These associations weakened as MHDI increased (interaction incident rate ratio [IRR] 0.95, 95% CI 0.90 to 0.98 for ACF; IRR 0.93, 95% CI 0.89 to 0.96 for HCI) and strengthened with higher SVI values (IRR 1.11, 95% CI 1.02 to 1.22 and IRR 1.17, 95% CI 1.08 to 1.27, respectively).Conclusion: Social inequalities in Brazilian municipalities modify the effect of ACF strategies on TB detection rates.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Poliovirus surveillance in Mayotte, Indian Ocean, reveals encephalomyocarditis virus type 1 and a wide diversity of non-polio enteroviruses. 印度洋马约特岛的脊髓灰质炎病毒监测显示存在1型脑心肌炎病毒和多种非脊髓灰质炎肠道病毒。

IF 1.5 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-09-08 DOI: 10.1093/trstmh/traf090

Ambre Tinard, Marie-Line Joffret, Morgane Levert, Sébastien Wurtzer, Maël Bessaud

{"title":"Poliovirus surveillance in Mayotte, Indian Ocean, reveals encephalomyocarditis virus type 1 and a wide diversity of non-polio enteroviruses.","authors":"Ambre Tinard, Marie-Line Joffret, Morgane Levert, Sébastien Wurtzer, Maël Bessaud","doi":"10.1093/trstmh/traf090","DOIUrl":"https://doi.org/10.1093/trstmh/traf090","url":null,"abstract":"Background: In 2023, Mayotte, a French department in the Mozambique channel, experienced a long drought that led to potable water restrictions. Although the French vaccination schedule makes polio vaccination compulsory for children, the large proportion of migrants on the island coupled with the water crisis raised concerns about the establishment of poliovirus transmission chains. Therefore, a surveillance was implemented to detect polioviruses in sewage sampled in the two main wastewater treatment plants.Methods: Samples collected from September 2023 through January 2024 were processed following the Global Polio Laboratory Network's algorithm.Results: Only two polioviruses were detected, both featuring a low number of nucleotide differences compared with vaccine strains, which suggested excretion by recently vaccinated people rather than circulation. The surveillance revealed viruses of the species Cardiovirus rueckerti in almost one-half of the samples. Furthermore, 305 non-polio enteroviruses were detected, belonging to various virus types of species Enterovirus betacoxsackie (53%), Enterovirus coxsackiepol (44%), and Enterovirus alphacoxsackie (3%).Conclusions: The poliovirus surveillance did not detect any wild or highly mutated poliovirus strains and did not highlight poliovirus circulation. This provided an opportunity to obtain the first overview of the non-polio enteroviruses circulating in Mayotte.Accession numbers: GenBank accession numbers PQ009012-PQ009102, PQ566710-PQ566937 and PQ868249-PQ868262.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145016188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Using digital annual household survey data to prioritize high-risk villages for tuberculosis active case-finding. 利用数字年度住户调查数据确定结核病活跃病例发现的高危村庄的优先次序。

IF 1.5 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-09-05 DOI: 10.1093/trstmh/traf089

Hamid Abdullah, Hemant Deepak Shewade, Manickam Ponnaiah, Mohammad Sarparajul Ambiya, Ruchit Nagar, Mohammed Shahnawaz, Rajeev Singh Dhakad, Kartik Sharma, Kalika Gupta, Purushotam Soni

{"title":"Using digital annual household survey data to prioritize high-risk villages for tuberculosis active case-finding.","authors":"Hamid Abdullah, Hemant Deepak Shewade, Manickam Ponnaiah, Mohammad Sarparajul Ambiya, Ruchit Nagar, Mohammed Shahnawaz, Rajeev Singh Dhakad, Kartik Sharma, Kalika Gupta, Purushotam Soni","doi":"10.1093/trstmh/traf089","DOIUrl":"https://doi.org/10.1093/trstmh/traf089","url":null,"abstract":"Background: Tuberculosis (TB) active case-finding (ACF) among high-risk populations is recommended to detect the missing people with TB. In Rajasthan, India, a state with a high TB prevalence:notification ratio, leveraging digital annual health survey data could enhance ACF by targeting villages with a high burden of TB risk factors.Methods: We conducted an ecological study across 19 districts of Rajasthan using data from the digital annual health survey. High-risk villages were identified based on three factors: multidimensional poverty index (MDPI), high proportion (>60%) of socially marginalized populations and geographic access (distance to primary health centre >7 km).Results: The survey covered 24.6 million individuals across 20 803 villages. Thirty-five percent of individuals belonged to socially marginalized populations. At the household level, 39% used solid fuels, indicating potential exposure to indoor air pollution. Nine percent of villages had high poverty (MDPI >0.21) and 25% had a high proportion (>60%) of socially marginalized populations. Approximately 34% of villages had at least one of the three high-risk factors.Conclusions: This study demonstrates the potential of existing digital annual survey data for targeted ACF. Further research is being planned to assess the yield of ACF in identified high-risk villages and to advocate for similar data-driven interventions in other settings.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145001097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiple ulcerative leprosy with delayed diagnosis in a non-endemic region. 在非流行地区诊断延误的多发性溃疡性麻风病。

IF 1.5 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-09-05 DOI: 10.1093/trstmh/traf094

Qian Zhang, Yang Xu, Chang-Qiang Li, Xiao-Feng Chen, Hui-Jing Zheng, Yu Liu, Wen-Feng Huang

引用次数: 0

Integrating the crowdsourced image-based morbidity hotspot surveillance for neglected tropical diseases (CIMS-NTDs) into Nigeria's healthcare system: a mixed methods study. 将基于众包图像的被忽视热带病发病热点监测整合到尼日利亚卫生保健系统：一项混合方法研究

IF 1.5 4区医学

Transactions of The Royal Society of Tropical Medicine and Hygiene Pub Date : 2025-09-04 DOI: 10.1093/trstmh/traf091

Ayoola O Bosede, Christopher S Oyamienlen, Uzochukwu G Ekeleme, Obinna G Udujih, Chinwe E Metuh, Evangeline T Oparaocha, Uchechukwu M Chukwuocha

{"title":"Integrating the crowdsourced image-based morbidity hotspot surveillance for neglected tropical diseases (CIMS-NTDs) into Nigeria's healthcare system: a mixed methods study.","authors":"Ayoola O Bosede, Christopher S Oyamienlen, Uzochukwu G Ekeleme, Obinna G Udujih, Chinwe E Metuh, Evangeline T Oparaocha, Uchechukwu M Chukwuocha","doi":"10.1093/trstmh/traf091","DOIUrl":"https://doi.org/10.1093/trstmh/traf091","url":null,"abstract":"Background: Traditional surveillance systems for neglected tropical diseases (NTDs) often suffer from underreporting, delays and limited reach, hindering effective disease control. This study describes the integration process of crowdsourced image-based morbidity hotspot surveillance for NTDs (CIMS-NTDs) into the government-led NTD program and assesses its operational performance and stakeholder experience.Methods: A mixed methods study embedded in an implementation research framework was conducted in Ondo State, Nigeria. A quasi-experimental design was used to compare CIMS-NTDs with the existing surveillance approach, while key informant interviews were used to explore stakeholder perceptions. Quantitative data were analysed using descriptive statistics and the Mann-Whitney U test, and qualitative data underwent reflexive thematic analysis.Results: The training session had in attendance of 30 NTD personnel from the state, local government areas and wards. Results showed a >400% improvement in CIMS-NTDs knowledge following the training session. CIMS-NTDs outperformed traditional surveillance, with 62 confirmed case reports versus only 3 under the conventional system (p=0.023). Onchocerciasis was the most frequently reported NTD (62.9%). Key informants highlighted improved community engagement, data accuracy and reporting efficiency but noted challenges such as digital accessibility and funding constraints.Conclusions: Integrating digital surveillance into national NTD programs enhances case detection, reporting and intervention strategies. Sustainable adoption requires government funding, capacity building and expanded digital infrastructure to improve accessibility and impact.","PeriodicalId":23218,"journal":{"name":"Transactions of The Royal Society of Tropical Medicine and Hygiene","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0