International Journal of Clinical and Diagnostic Pathology最新文献_第3页

To compare the expression of p53 with hormonal receptor status in breast carcinoma: An immunohistochemical study 乳腺癌中p53表达与激素受体状态的比较:免疫组织化学研究

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI: 10.33545/pathol.2023.v6.i1a.503

Dr. Satinder Pal Kaur, Dr. Harjot Kaur, Dr. Sanjay Piplani, Dr. Karamjit Singh Gill, Dr. Mandeep Singh

引用次数: 0

Serum level of cripto -1 in hepatitis B virus & hepatitis C virus induced hepatocellular carcinoma 乙型肝炎病毒和丙型肝炎病毒诱导的肝细胞癌患者血清隐码蛋白-1水平的变化

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI: 10.33545/pathol.2023.v6.i3a.532

Azza Abdelfattah Teama, M. Hagras, F. El-Kalla, H. Mourad

引用次数: 0

A retrospective study on significance of total and free Prostate specific antigen (PSA) level with their ratio in diagnosis of prostatic lesions at a tertiary care centre 回顾性研究总和游离前列腺特异性抗原(PSA)水平及其比值在三级保健中心前列腺病变诊断中的意义

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI: 10.33545/pathol.2023.v6.i3b.537

Dr. Vijay C Popat, Dr. Gunjan Rathod, Dr. Jiya V Popat

引用次数: 0

Gastrointestinal stromal tumors: Clinicopathological correlations 胃肠道间质瘤:临床病理相关性

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI: 10.33545/pathol.2023.v6.i3b.536

Saja Laith Mikhlif, Khitam Razzak Al-Khafaji

{"title":"Gastrointestinal stromal tumors: Clinicopathological correlations","authors":"Saja Laith Mikhlif, Khitam Razzak Al-Khafaji","doi":"10.33545/pathol.2023.v6.i3b.536","DOIUrl":"https://doi.org/10.33545/pathol.2023.v6.i3b.536","url":null,"abstract":"Background: Histological, genetic, and anatomical characteristics distinguish gastrointestinal stromal tumours (GISTs) from other neoplasms. GISTs, the most common gastrointestinal (GI) mesenchymal tumours, occur 7 to 19 times per million annually. This study discusses GIST clinicopathological relationships and how they might be used to optimize risk stratification and adjuvant treatment. Method: Cross-sectional research of 99 gastrointestinal stromal tumour patients from January 2019 to January 2023 at Medical city/GIT and hepatology teaching hospital and Medical city teaching complex/teaching laboratories/histopathology department. All patients were queried about age (years), gender, tumour location and size, mitotic rate (high or low), and cancer risk group (high, moderate, low, and very low). Results: Mean patient age 52.5 ± 13 years old. 32.3% of patients over 60, 24.3% 51-60. Males 54.5%, females 45.5%. Patients 52.5% had lower Mitotic rate 550 HPF, 49.5% are high risk. 58.59% of patients have stomach tumours, 22.22% have large bowel tumours, and 19.19% have small intestine tumours. Mitotic rate is associated with risk; 97.9% of high Mitotic rates are high risk. Site and danger are also associated: 24.1% of stomach tumours are high risk while 72.7% of small intestinal tumours are extremely low risk. No substantial connection exists between age and gender and risk. Risk category affects tumour size: high risk has large tumours, whereas low risk has small tumours. Conclusion: Our analysis confirms key GIST prognostic correlations. We confirmed that high mitotic rate, tumour location, and size influence risk category, validating previous research. Age and gender affected GIST prevalence, but not risk category in our group. These results emphasise the need for extensive risk classification in GISTs for effective patient care and need additional study of population-specific demographics and features.","PeriodicalId":232143,"journal":{"name":"International Journal of Clinical and Diagnostic Pathology","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135446262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Expression of p16 in cervical intraepithelial neoplasm and invasive cervical carcinoma: An immunohistochemical study p16在宫颈上皮内肿瘤和浸润性宫颈癌中的表达:免疫组织化学研究

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI: 10.33545/pathol.2023.v6.i1a.502

Dr. Supreet Kaur, Dr. Sanjay Piplani, Dr. Manas Madan, Dr. Karamjit Singh Gill

引用次数: 0

Role of chitotriosidase as inflammatory marker of endothelial dysfunction in type-2 diabetes mellitus 壳三酸苷酶作为2型糖尿病内皮功能障碍炎症标志物的作用

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI: 10.33545/pathol.2023.v6.i3a.526

Heba Elsayed Shamla, Dina Adam Ali, Samy Abd El-Kader Khudair, H. A. Elserogy

引用次数: 0

Unusual metastasis of renal cell carcinoma to index finger of hand without any evidence of primary renal tumour: A rare case 肾细胞癌转移至食指而无原发性肾肿瘤证据:罕见病例

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI: 10.33545/pathol.2023.v6.i3a.528

Dr. Hardik Jain, Patel Kinjal Shashikantbhai, Dr. Smita Jhaveri

引用次数: 0

Chondromyxoid fibroma of nasal septum: A case report 鼻中隔软骨粘液样纤维瘤1例

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI: 10.33545/pathol.2023.v6.i2b.524

G. C, B. Menon

引用次数: 0

A review of the predictive values and malignancy risks of the YOKOHAMA system for reporting breast fine needle aspiration cytology 回顾横滨系统报告乳腺细针穿刺细胞学的预测价值和恶性风险

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI: 10.33545/pathol.2023.v6.i3a.530

Dr. Lamees Abd Al Raheem Nabat, Dr. Hussam Hasson Ali

{"title":"A review of the predictive values and malignancy risks of the YOKOHAMA system for reporting breast fine needle aspiration cytology","authors":"Dr. Lamees Abd Al Raheem Nabat, Dr. Hussam Hasson Ali","doi":"10.33545/pathol.2023.v6.i3a.530","DOIUrl":"https://doi.org/10.33545/pathol.2023.v6.i3a.530","url":null,"abstract":"Background: FNA reliably diagnoses breast lesions without surgery. Radiologists, surgeons, and oncologists can quickly communicate cytology results with a standardized care plan. The 2017 IAC conference in Yokohama established a comprehensive breast cytology system. This research examined the distribution of fine needle aspiration (FNA) cytology of breast lesions using the Yokohama 5 categories and the risk of malignancy (ROM) and predictive values of breast cytology using the International Academy of Cytology (IAC). Method: The study was conducted in the cytology laboratory of the Center of Early Detection of Breast Cancer, Oncology Teaching Hospital, Medical City Complex, Baghdad. A total of 108 consecutive patients were included in the study, and slides were collected for each patient. Results: Most patients were symptomatic and 45.9 years old. 23 (21.3%) lesions had inadequate material and were C1, whereas 14 (13%) had benign-looking epithelium and were C2. 37 (34.3%) instances exhibited mild to moderate nuclear atypia, whereas 4 (3.7%) had paucicellular smears but notable atypia and were C4. Thirty C5 lesions (27.8%) were malignant. C3 had 5.4% ROM, C4 75%, and C5 100%. Three settings determined predicted values. Group A exclusively considered C5 instances positive, with a sensitivity of 85.7%, specificity and positive predictive value (PPV) of 100%, and NPV of 77.3%. Group B regarded C4 and C5 instances as positive, with sensitivity of 94.3%, specificity of 94.1%, NPV of 88.9%, and PPV of 97.1%. With 100% sensitivity and 67.3% PPV, Group C deemed C3, C4, and C5 cases positive. Conclusion: The FNA had the greatest specificity (100%), sensitivity (100%), and accuracy (94.2%) when C4 and C5 were positive. The research emphasizes the need for a standardized breast cytology system to facilitate communication between radiologists, surgeons, and oncologists.","PeriodicalId":232143,"journal":{"name":"International Journal of Clinical and Diagnostic Pathology","volume":"114 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121590246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spectrum of histopathological lesions of nasal cavity, paranasal sinus and nasophrynx at tertiary care centre 三级保健中心的鼻腔、副鼻窦及鼻咽组织病理病变谱

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI: 10.33545/pathol.2023.v6.i1a.507

Dr. Mushkan A Sorathya, Dr. Arpita Makwana, Dr. Nandini J Desai

引用次数: 0