International Journal of Clinical and Diagnostic Pathology最新文献_第2页

Occurrence of Oral, Oropharyngeal and Laryngeal Cancers in Saurashtra Region, Gujarat, India A study of 1,006 cases of Oral Lesions 印度古吉拉特邦索拉斯特拉地区口腔癌、口咽癌和喉癌的发生:1006例口腔病变的研究

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-04-01 DOI: 10.33545/pathol.2023.v6.i2a.514

Dr. Konika Kherajani, Dr. Krina Shah, Dr. Vijay C Popat

引用次数: 0

Correlation of fine needle aspiration cytology with histopathological examination in the diagnosis of spectrum of thyroid lesions 细针穿刺细胞学检查与组织病理学检查在甲状腺病变谱诊断中的相关性

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-04-01 DOI: 10.33545/pathol.2023.v6.i2a.511

Dr. Chita Subba, Dr.Barnali Das, Dr. Amrit Sarmah, Dr. Geetanjali Gogoi, Dr. Priyanka Goutam, Dr. Akash Pradeep Bhuyan

引用次数: 0

Study of CD73 Expression on B Lymphocytes in patients with chronic lymphocytic leukemia 慢性淋巴细胞白血病患者B淋巴细胞CD73表达的研究

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-04-01 DOI: 10.33545/pathol.2023.v6.i2a.513

Hany Mostafa Kamel El Zohery, A. Gawaly, W. Mohamed, Aisha Abdellatif El Said

引用次数: 0

P16 expression as a diagnostic parameter of endometrial carcinoma and endometrial hyperplasia P16表达作为子宫内膜癌和子宫内膜增生的诊断指标

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-04-01 DOI: 10.33545/pathol.2023.v6.i2a.509

Dr. Asmaa Shakir Hadi, Dr. Hadi M AL-Mosawi

引用次数: 0

An unusal presentation of mature ovarian teratoma in a young girl: A rare case report 罕见的成熟卵巢畸胎瘤的表现在一个年轻的女孩:一个罕见的病例报告

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-04-01 DOI: 10.33545/pathol.2023.v6.i2b.521

Dr. Sriram V, Dr. Arunagiri Raja, Dr. Revathi, Dr. Erli Amel Ivan, Dr. Ramya G, Dr. V Vigneswaramoorthi

{"title":"An unusal presentation of mature ovarian teratoma in a young girl: A rare case report","authors":"Dr. Sriram V, Dr. Arunagiri Raja, Dr. Revathi, Dr. Erli Amel Ivan, Dr. Ramya G, Dr. V Vigneswaramoorthi","doi":"10.33545/pathol.2023.v6.i2b.521","DOIUrl":"https://doi.org/10.33545/pathol.2023.v6.i2b.521","url":null,"abstract":"Introduction: Solid teratomas are relatively more common in infants and children (accounting for 15% of ovarian tumor). Though the peak age incidence is at second decade [1] . Metastatic implantation of glial tissue on surfaces of visceral or parietal peritoneum is called as Gliomatosis peritonei (GP) and its occurrence is very rare. Case Report: A 10 year old girl presented with the complaints of vague abdominal pain and discomfort for two months. Ultrasonography of the abdomen showed a heterogenous solid cystic tumor of 12 X 15 x 10 cm noted in left side of the ovary adherent to the fallopian tube. Left salpingoopherectomy was done and histopathology show features of mature solid ovarian teratoma with Gliomatosis peritonei. Conclusion: Gliomatosis peritonei is implantation of mature glial tissue on surfaces of peritoneum. It is often associated with ovarian teratoma of any grade. This is always present with massive peritoneal implantation, optimal resection is difficult. Although residual peritoneal disease can be totally quiescent over a long period, long-term follow-up is needed for patients with residual disease. A more conservative surgical approach may be carried out in patients with massive peritoneal spread.","PeriodicalId":232143,"journal":{"name":"International Journal of Clinical and Diagnostic Pathology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131627775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The potential role of villin 1 and estrogen receptor (ER) in differentiation between endocervical adenocarcinoma and endometrial adenocarcinoma 绒毛蛋白1和雌激素受体(ER)在宫颈内膜腺癌和子宫内膜腺癌分化中的潜在作用

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI: 10.33545/pathol.2023.v6.i1a.506

Mai Elshenawy Elsemelawy, A. Eid, Aymen Mohamed El-Saka andAhmed Abdel Azeim Menaisy

{"title":"The potential role of villin 1 and estrogen receptor (ER) in differentiation between endocervical adenocarcinoma and endometrial adenocarcinoma","authors":"Mai Elshenawy Elsemelawy, A. Eid, Aymen Mohamed El-Saka andAhmed Abdel Azeim Menaisy","doi":"10.33545/pathol.2023.v6.i1a.506","DOIUrl":"https://doi.org/10.33545/pathol.2023.v6.i1a.506","url":null,"abstract":"Background: Endocervical adenocarcinoma (ECAC) is the 4th most common cancer in females globally. It has been ranked the 14th most common cancer in Egyptian females. The aim of this work was to study immunohistochemical expression of villin1 in endocervical and endometrial adenocarcinoma, immunohistochemical expression of ER in endocervical and endometrial adenocarcinoma and evaluate the potential role of villin 1 and ER expression in differentiation between endocervical & endometrial adenocarcinoma. Methods: This retrospective study was carried out on 60 cases of endocervical & endometrial endometroid adenocarcinoma. Patients were classified into two equal groups: Group I: Cases of endocervical adenocarcinomas and Group II: Cases of endometrial endometroid adenocarcinomas. Results: The positive predictive value of ER as a correlation between ER expression and clinicopathological characteristics has been addressed in our study was 100%. The negative predictive value was 73.1%. The positive predictive value of using panel of villin and ER expression and clinicopathological characteristics has been addressed in our study was 88.8%, the negative predictive value was 66.6%. Conclusions: Villin1 is good diagnostic tool had high specificity in differentiating endocervical and endometroid adenocarcinoma and has a predictive value in ECAC. ER is good diagnostic tool in differentiating between endocervical and endometroid adenocarcinomas and has predictive value in endometroid adenocarcinoma.","PeriodicalId":232143,"journal":{"name":"International Journal of Clinical and Diagnostic Pathology","volume":"696 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122982767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of JAK2 V617F mutation prevalence in a sample of Iraqi patients with Beta thalassemia major 伊拉克乙型地中海贫血患者JAK2 V617F突变患病率调查

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI: 10.33545/pathol.2023.v6.i2b.525

Dr. Saba Abdulmahdi Abdul Ameer, Dr. Abeer Anwer Ahmed

引用次数: 0

Thrombotic complications of COVID-19 and its relation with NADPH oxidase and tissue factor 新冠肺炎血栓性并发症及其与NADPH氧化酶和组织因子的关系

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI: 10.33545/pathol.2023.v6.i3b.538

Sarah Samy Mohamed Abdelghany, Ragia Samir Sharshar, Amira Youssef Ahmed, Maaly Mohamed Mabrouk, Enas Arafa Elzamarany

{"title":"Thrombotic complications of COVID-19 and its relation with NADPH oxidase and tissue factor","authors":"Sarah Samy Mohamed Abdelghany, Ragia Samir Sharshar, Amira Youssef Ahmed, Maaly Mohamed Mabrouk, Enas Arafa Elzamarany","doi":"10.33545/pathol.2023.v6.i3b.538","DOIUrl":"https://doi.org/10.33545/pathol.2023.v6.i3b.538","url":null,"abstract":"Background: The severe acute respiratory syndrome corona-virus 2 (SARS CoV-2) is the virus responsible for the corona-virus disease 19 (COVID-19), a highly contagious and pathogenic viral illness. Individuals with severe illnesses may develop acute respiratory distress syndrome (ARDS) and have altered coagulation functioning, which puts them at risk for developing thromboembolic consequences. This work aimed to evaluate the relation between NADPH oxidase 2 (NOX2), tissue factor (TF) and the thrombotic complications in COVID-19 infection. Subjects: This case-control work was performed on 180 subjects. Individuals with COVID-19 group included 100 patients proved to be COVID-19 positive. Control group included 80 apparently healthy age and sex matched subjects.Methods: Blood levels of NOX2, TF and Interleukin-6 (IL-6) had been assessed by sandwich enzyme-linked immune-sorbent assay (ELISA) method.Results: a substantial increase was existed in NOX2, TF and IL-6 in COVID-19 patients and patients with thromboembolic events (TEEs) when compared with control subjects and patients without TEEs. ROC curve for serum NOX2 to predict thromboembolic events showed sensitivity 96.55, specificity 94.37 and positive predictive value 87.5. ROC curve for plasma TF to predict thromboembolic events had sensitivity 93.10, specificity 92.96, and positive predictive value 84.4.Conclusions: High levels of NADPH oxidase2, tissue factor and IL-6 are associated with increased incidences of the thromboembolic complications, mortality rates and admission at ICU in individuals with COVID-19.","PeriodicalId":232143,"journal":{"name":"International Journal of Clinical and Diagnostic Pathology","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135698894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of Anemia: A comprehensive review 贫血的流行:一个全面的回顾

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI: 10.33545/pathol.2023.v6.i3b.539

Dr. Sujatha Tejavat

引用次数: 0

Immunohistochemistry at rescue in the cancers of unknown primary origin 免疫组织化学对原发不明癌症的拯救作用

International Journal of Clinical and Diagnostic Pathology Pub Date : 2023-01-01 DOI: 10.33545/pathol.2023.v6.i3b.540

Megha H Lalcheta, Vijay C Popat, Alaknanda Atara

{"title":"Immunohistochemistry at rescue in the cancers of unknown primary origin","authors":"Megha H Lalcheta, Vijay C Popat, Alaknanda Atara","doi":"10.33545/pathol.2023.v6.i3b.540","DOIUrl":"https://doi.org/10.33545/pathol.2023.v6.i3b.540","url":null,"abstract":"Aims: To identify and explore the role of immune histochemical markers in the diagnosis of malignancies of unknown primary origin.Background: Cancer of unknown primary (CUP) origin is a heterogenous group of cancers explained by the presence of metastatic disease with no identified primary tumor at presentation. These malignant neoplasms with unknown primary origin can be identified and classified by the use of a robust IHC panel which may permit development of tailored treatment algorithm with specific targeted agents. Methods: In the current study, Histopathology and biopsy samples from 38 patients were included which were diagnosed as CUP and referred to IHC department, M. P. Shah medical college and hospital, Jamnagar from 2019 to 2023. CUP were diagnosed and classified of their histologic types on basis of hematoxylin and IHC slides. Results: From 2019 to 2023, out of 4026 cases, CUP constitutes 0.99% (~1%). The age group (60-69) years have the highest cases 14/40 cases with equal distribution in both sexes. Lymph node represents (42.5%) which is the most common presenting site followed by liver (12.5%) and lung (10%). In 50% of the cases, the primary site was determined; whereas 37.5% cases were remained unknown for primary and 12.5% cases were given an only differential diagnosis. Adenocarcinoma (66.6%) was the most common subtype, followed by squamous cell carcinoma (13.15%), undifferentiated neoplasm (10.52%). Conclusions: The most common presenting sites were lymph nodes, liver, lungs and others. CUP cases are uncommon (0.88%) and primary origin of these CUPs were identified in 50% cases. Sub typing of primary site were adenocarcinoma, squamous cell carcinoma and carcinoma with undifferentiated neoplasm.","PeriodicalId":232143,"journal":{"name":"International Journal of Clinical and Diagnostic Pathology","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134887402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0