Topics in Stroke Rehabilitation最新文献

{"title":"Physical dependence, self-efficacy, and resilience in stroke patients: a double-moderated mediation model of healthcare group and pre-stroke employment.","authors":"Hsiu-Ling Hsieh, Chia-Pang Shih, Wen-Yuan Lee, Ching-Hua Chu, Sung-Yuan Sung, Huey-Fen Wang","doi":"10.1080/10749357.2026.2723405","DOIUrl":"https://doi.org/10.1080/10749357.2026.2723405","url":null,"abstract":"<p><strong>Aims: </strong>To examine the concurrent relationships between physical dependence, self-efficacy, and resilience among stroke patients, and to explore whether the healthcare intervention group and pre-stroke employment status jointly moderate this mediated relationship.</p><p><strong>Design: </strong>A cross-sectional study using moderated mediation analysis.</p><p><strong>Methods: </strong>A total of 123 participants were recruited from a neurology ward in a hospital. Instruments included the Chinese version of the Resilience Scale, the Stroke Self-Efficacy Questionnaire, and the Modified Rankin Scale. Descriptive statistics, correlation analyses, and independent samples t-tests were performed. PROCESS macro (Model 21) with 5,000 bootstrap samples was applied to examine the hypothesized double-moderated mediation model.</p><p><strong>Results: </strong>Self-efficacy mediated the concurrent relationship between physical dependence and resilience. The healthcare intervention group moderated the relationship between physical dependence (operationalized as a binary threshold [mRS ≤ 3 vs. mRS = 4]) and self-efficacy, whereas pre-stroke employment status moderated the relationship between self-efficacy and resilience. Crucially, the conditional indirect pathway was statistically significant exclusively within the routine care group among patients who were unemployed prior to stroke onset.</p><p><strong>Conclusions: </strong>Greater physical dependence is concurrently associated with lower resilience, a concurrent relationship where lower self-efficacy serves as a partial mediator. This conditional indirect pathway is particularly pronounced among individuals who receive standard routine care and concurrently lack pre-stroke occupational engagement. For patients who were employed before stroke, the concurrent link between self-efficacy and resilience is absent, suggesting that their psychological adaptation is characterized by distinct environmental or vocational factors.</p><p><strong>Implications for practice and patient care: </strong>Routine assessment of physical dependence is crucial for evaluating current functional status and adjusting care plans accordingly. Incorporating social role context and employment history into rehabilitation strategies may further support psychosocial adaptation in stroke patients.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"1-15"},"PeriodicalIF":2.3,"publicationDate":"2026-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148971328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new map for stroke prevention: a commentary on empowering TIA and minor stroke patients through personalized lifestyle interventions.","authors":"James Faulkner, Lee Stoner","doi":"10.1080/10749357.2026.2729176","DOIUrl":"https://doi.org/10.1080/10749357.2026.2729176","url":null,"abstract":"","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"1-6"},"PeriodicalIF":2.3,"publicationDate":"2026-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148945672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of ankle-foot orthosis-related conditions on muscle activity, spasticity, and psychosocial outcomes after stroke: a systematic review and meta-analysis.","authors":"Hyunsik Yoon","doi":"10.1080/10749357.2026.2725690","DOIUrl":"https://doi.org/10.1080/10749357.2026.2725690","url":null,"abstract":"<p><strong>Background: </strong>Ankle-foot orthoses (AFOs) are widely used after stroke to improve ankle stability, foot clearance, and gait performance. However, their effects on lower-limb muscle activity, spasticity, and psychosocial outcomes remain uncertain.</p><p><strong>Objectives: </strong>To evaluate the effects of AFO-related conditions on electromyographic muscle activity, spasticity, and psychosocial outcomes after stroke.</p><p><strong>Methods: </strong>PubMed, MEDLINE, Embase, CINAHL, Web of Science, and CENTRAL were searched for studies involving adults with stroke that examined AFO-related conditions and reported electromyographic muscle activity, spasticity, or psychosocial outcomes. Standardized mean differences (SMDs) and 95% confidence intervals (CIs) were pooled using random-effects models.</p><p><strong>Results: </strong>Ten studies involving 931 participants were included. AFO-related conditions were associated with reduced lower-limb EMG activity (SMD =  -0.40, 95% CI - 0.74 to -0.06; <i>p</i> = 0.02; I² = 11%) and spasticity (SMD =  -0.41, 95% CI - 0.77 to -0.05; <i>p</i> = 0.03; I² = 0%). No significant pooled effect was observed for psychosocial outcomes (SMD = 0.04, 95% CI - 0.28 to 0.36; <i>p</i> = 0.79; I² = 66%).</p><p><strong>Conclusions: </strong>AFO-related conditions may reduce lower-limb EMG activity and spasticity after stroke, whereas psychosocial effects remain unclear. Reduced EMG activity may reflect mechanical assistance but may also indicate reduced active dorsiflexor recruitment in individuals with residual voluntary ankle function. AFO prescription should therefore be individualized according to residual motor function, spasticity, gait stability, safety, patient preference, and rehabilitation goals.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"1-10"},"PeriodicalIF":2.3,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148901142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced swallowing function and quality of life in post-stroke dysphagia: superior efficacy of tongue-nape acupuncture combined with tDCS.","authors":"Na Liang, Yang Xue, Qi Pan, Wenzhen Shi, Xin Lei, Xuewei Li, Jin Qiao","doi":"10.1080/10749357.2026.2723407","DOIUrl":"https://doi.org/10.1080/10749357.2026.2723407","url":null,"abstract":"<p><strong>Background: </strong>This study evaluated the combined effects of Tongue-Nape Acupuncture (TNA) and Transcranial Direct Current Stimulation (tDCS) on 85 post-stroke dysphagia (PSD) patients.</p><p><strong>Methods: </strong>Participants were assigned to either a tDCS-only group (<i>n</i> = 40) or a TNA + tDCS group (<i>n</i> = 45). Swallowing function (Water Swallowing Test, Standard Swallowing Assessment) and Quality of Life (QoL) were assessed. Serum levels of neural injury markers (S-100β, NSE, MMP-9, Hcy, hs-CRP) were measured, alongside brain activity (near-infrared imaging) and muscle function (EMG).</p><p><strong>Results: </strong>The TNA + tDCS group achieved significantly greater improvements in swallowing scores and a higher overall clinical response rate (91.1% vs. 77.5%) compared to the tDCS-only group (<i>p</i> < 0.05). The combination therapy led to significant reductions in neural injury biomarkers and increased oxyhemoglobin concentrations in sensorimotor and prefrontal areas, indicating positive neurobiological changes and enhanced brain activity. EMG results also showed improved muscle function and coordination in the combined group. No significant difference in adverse reactions was observed between groups. In addition, serum biomarker assay results demonstrated that, post-intervention, the combination group exhibited significantly decreased levels of S-100β, NSE, MMP-9, homocysteine, and high-sensitivity C-reactive protein, indicating benign neurobiological alterations.</p><p><strong>Conclusion: </strong>The study concludes that combining TNA and tDCS is a promising strategy for improving swallowing and feeding functions, enhancing QoL, and offering potential neuroprotective benefits for patients with PSD.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"1-13"},"PeriodicalIF":2.3,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148892247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reliability and validity of stroke self-efficacy questionnaire: a Vietnamese version.","authors":"Tinh Thi Thanh Nguyen, Thanh Tran Ngoc Dang, Vien Truong Nguyen, Hong Thuy Phuong Huynh","doi":"10.1080/10749357.2026.2618003","DOIUrl":"10.1080/10749357.2026.2618003","url":null,"abstract":"<p><strong>Introduction: </strong>Self-efficacy significantly influences the recovery process following a stroke. A reliable and valid measurement tool is of paramount importance for self-efficacy assessment. The stroke self-efficacy questionnaire (SSEQ) is a specialized measurement tool designed for post-stroke patients.</p><p><strong>Aim: </strong>The study was conducted to translate the English SSEQ version into and culturally adapt it to the Vietnamese version and to evaluate the reliability and validity of the latter.</p><p><strong>Materials and methods: </strong>The translation and cultural-adaptation process included translation-back steps according to Beaton's guidelines, content validity index (CVI) was assessed on 10 experts, face validity via pilot on 10 patients, factor analysis on 305 patients, and reliability assessment on 80 replications.</p><p><strong>Results: </strong>The SSEQ-V achieved CVI = 100%, all patients clearly assessed the form and content suitability, internal reliability reached Cronbach's alpha >0.95, and test-retest reliability reached ICC = 0.979. Factor analysis supported a two-factor structure including daily functional activities and self-management with high fit indices.</p><p><strong>Conclusion: </strong>The SSEQ-V should be applied in post-stroke patients to develop self-management intervention programs to improve their recovery in Vietnam.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"651-663"},"PeriodicalIF":2.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146067161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intermittent theta-burst stimulation for post-stroke cognitive impairment: a double-blind randomized controlled trial.","authors":"Yueying Wang, Huiyue Feng, Jingang Dai, Qin Wang","doi":"10.1080/10749357.2025.2605295","DOIUrl":"10.1080/10749357.2025.2605295","url":null,"abstract":"<p><strong>Background: </strong>Post-stroke cognitive impairment (PSCI) significantly affects patients' quality of life. Although standard repetitive transcranial magnetic stimulation (rTMS) has shown promising efficacy, the effectiveness of the newer, more time-efficient intermittent theta-burst stimulation (iTBS) remains to be validated.</p><p><strong>Methods: </strong>Two groups of randomly assigned patients with PSCI received either four weeks of two 600-pulse iTBS treatment sessions with a 50-minute interval between sessions or sham stimulation. Cognitive function and activities of daily living were assessed before and after treatment using the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), and the Modified Barthel Index (MBI).</p><p><strong>Results: </strong>Sixty patients were enrolled, and 57 completed the study. Patients in the iTBS group demonstrated significantly higher MMSE scores, MoCA scores, and MBI scores compared to the sham stimulation group (<i>p</i> < 0.05for all). Only one patient experienced a headache during treatment, and no serious adverse events occurred.</p><p><strong>Conclusion: </strong>Two blocks of iTBS therapy with 600 pulses each at 50-minute intervals demonstrated favorable therapeutic effects in patients with PSCI.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"609-617"},"PeriodicalIF":2.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145834626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital twins in stroke rehabilitation: a scoping review of objectives, data sources, mechanisms, outcomes, and desirable properties.","authors":"Alejandro García-Rudolph, Mark Andrew Wright, Claudia Teixidó-Font, Rocio Sanchez-Carrion, Gunnar Cedersund, Eloy Opisso","doi":"10.1080/10749357.2025.2584031","DOIUrl":"10.1080/10749357.2025.2584031","url":null,"abstract":"<p><strong>Background: </strong>Digital Twins (DTs) have transitioned from theory to reality, with growing applications in healthcare. Data generated by technologies (e.g. rehabilitation robots), essential for DT implementation, though widely produced in clinical settings, remains untapped in DT stroke rehabilitation, highlighting a gap compared to broader healthcare use.</p><p><strong>Objectives: </strong>We conducted a scoping review to i) define DT rehabilitation objectives, their input data, generation methods and user involvement; ii) analyze mechanisms underpinning DT models and outputs; iii) map key stakeholders driving innovation; iv) identify desirable properties for DT studies from broader healthcare literature and map them to stroke rehabilitation DT studies.</p><p><strong>Methods: </strong>Following PRISMA-ScR guidelines, PubMed, Scopus, Web of Science and Google Scholar were searched for studies including only empirical data. Full-text reviews were conducted by three reviewers through repeated calibration.</p><p><strong>Results: </strong>Sixteen studies were included, addressing five rehabilitation objectives: upper-limb (10), gait (3), and engagement, mental health, and general/planning (1 each). Patient sample sizes varied widely, with one retrospective study including 1,216 patients, while 15 studies involved 54 patients in total (median = 1).We identified 16 DTs mechanisms (e.g. variational autoencoders, Hill muscle models) and outcomes (e.g. exoskeleton control, upper-limb exercise delivery, gait torque estimation, impaired hand-mobility quantification). Academic institutions conducted 12 studies, Europe contributed 8 studies across 6 countries. Of 25 desirable properties identified, 8 (e.g. reproducible algorithms) showed high adoption, while 15 (e.g. cost-effectiveness, clinical integration) showed low/very low adoption by included studies.</p><p><strong>Conclusions: </strong>DTs in stroke rehabilitation show promise, though challenges remain (e.g. patient involvement, scalability).</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"704-718"},"PeriodicalIF":2.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145459843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Aerobic exercise increases brain-derived neurotrophic factor (BDNF) in sub-acute stroke: a randomized controlled trial.","authors":"Christopher P Mackay, Suzanne Kuys, Mia Schaumberg, Li-Ann Leow, Sandy Brauer","doi":"10.1080/10749357.2026.2628540","DOIUrl":"10.1080/10749357.2026.2628540","url":null,"abstract":"<p><strong>Background: </strong>Brain-derived neurotrophic factor (BDNF) is a key neurotrophin due to its role in neuron process outgrowth, plasticity, and neuronal survival. Aerobic exercise can induce BDNF release and may ultimately maximize post-stroke recovery.</p><p><strong>Objectives: </strong>This study aimed to determine if a program of moderate-to-high-intensity aerobic exercise increased concentrations of BDNF in subacute stroke survivors compared to usual care.</p><p><strong>Methods: </strong> A parallel-group, RCT was undertaken in people with subacute stroke undergoing rehabilitation. Participants were randomly allocated to usual care (control group) or usual care plus an 8-week program of moderate-high intensity treadmill walking (3 x 30 min sessions per week) (experimental group). Serum BDNF was collected by blinded assessors at baseline (Week 0), at the end of the intervention period (Week 8), and at 6 months follow up (Week 26).</p><p><strong>Results: </strong>Sixty-seven participants (<i>n</i> = 67) were recruited to the study (avg time post-stroke: 26 days). A between-group difference in BDNF levels across the three time points (F = 3.14, <i>p</i> = 0.048) was found. From Week 0 to Week 8, BDNF levels in the experimental group increased by 18% (<i>p</i> = 0.020) and then decreased from Week 8 to Week 26 by 18% (<i>p</i> = 0.021), returning to baseline levels. No change was found for the control group (Week 0 to Week 8 <i>p = 0.378</i>, Week 8 to Week 26 <i>p = 0.412</i>).</p><p><strong>Conclusions: </strong>As concentrations of BDNF increased immediately after a program of aerobic exercise, this may present a potential neurobiological mechanism to enhance recovery after stroke.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"597-608"},"PeriodicalIF":2.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146228596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adaptation, cross-cultural validation, and assessment of measurement properties of the French-Canadian version of the Determinants of Implementation Behavior Questionnaire (DIBQ) for use regarding sexual health services in stroke rehabilitation.","authors":"Louis-Pierre Auger, Isabelle Quintal, Annie Rochette, Dorra Rakia Allegue, Brigitte Vachon, Aliki Thomas, Johanne Higgins","doi":"10.1080/10749357.2025.2605291","DOIUrl":"10.1080/10749357.2025.2605291","url":null,"abstract":"<p><strong>Background: </strong>Clinicians report that numerous personal and environmental factors affect their ability to address sexuality in their practice. However, no validated tool in any language exists to assess these factors.</p><p><strong>Objectives: </strong>To translate and cross-culturally validate the Determinants for Implementation Behavior Questionnaire (DIBQ) to sexual health (SH) services for Canadian French speaking stroke rehabilitation clinicians and assess its measurement properties.</p><p><strong>Methods: </strong>The DIBQ was adapted for sexual health services and translated into Canadian French using a back-translation process. The resulting DIBQ-SH was pretested, improved, and was then sent to clinicians of seven rehabilitation centers in Quebec, Canada, for testing. Exploratory factor analysis, Cronbach's alpha, intraclass correlation coefficients (ICC), standard error of measurement (SEM), minimal detectable change (MDC), and floor and ceiling effects analysis were computed.</p><p><strong>Results: </strong>A sample of 184 clinicians completed the DIBQ-SH. Factor analysis revealed a six-factor solution explaining 55.2% of the variance. Internal consistency for the total score (α = 0.94) and subscales \"Capabilities\" (α = 0.91), \"Support and resources\" (α = 0.87), \"Emotions\" (α = 0.83), \"Planning and delivery\" (α = 0.85), \"Beliefs\" (α = 0.83), and \"Motivation\" (α = 0.78) was considered \"good\" to \"very good.\" Test-retest reliability was \"good\" for the total score and 5/6 subscales (ICC = 0.79-0.88), excluding the \"Beliefs\" subscale, which was \"critical\" (ICC = 0.59). SEM and MDC were also presented.</p><p><strong>Conclusion: </strong>The DIBQ-SH showed good measurement properties for assessing factors that influence provision of sexual health services among French Canadian speaking clinicians who provide services to persons with stroke.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"694-703"},"PeriodicalIF":2.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145878714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Asymmetry in fractional anisotropy of the corticospinal tract correlates with measures of body structure/function and activity in the chronic phase after stroke.","authors":"Tiago Voigt Gava, Sook-Lei Liew, Claudia da Costa Leite, Carlos Toyama, Nathália Helena Vieira Ribeiro, Adriana Bastos Conforto","doi":"10.1080/10749357.2025.2605292","DOIUrl":"10.1080/10749357.2025.2605292","url":null,"abstract":"<p><strong>Background: </strong>Imaging biomarkers of corticospinal tract (CST) involvement show significant correlations with the upper extremity Fugl-Meyer Assessment (FMA) - a measure of body structure and function within the International Classification of Functioning, Disability, and Health framework (ICF) - particularly in the acute and subacute phases after stroke. However, the relationships between CST biomarkers and the FMA, as well as with ICF activity-level outcomes, remain insufficiently characterized.</p><p><strong>Objective: </strong>This cross-sectional study investigated, in 36 individuals in the chronic phase after stroke, the correlation between three markers of CST integrity, (1) asymmetry in fractional anisotropy measured in the posterior limb of the internal capsule (FA-PLIC), (2) asymmetry in cerebral peduncle (CP) area, and (3) the CST lesion load, and outcomes of body function/structure and activity.</p><p><strong>Methods: </strong>The participants were assessed with the FMA and the Wolf Motor Function Test (WMFT) consisting of a timed component (WMFT-Time) and the Functional Ability Scale (WMFT-FAS). Associations between imaging and clinical measures were analyzed with Pearson correlation coefficients.</p><p><strong>Results: </strong>FA-PLIC asymmetry was significantly correlated with FMA (<i>r</i> = 0.33; <i>p</i> = 0.047) and WMFT-FAS (<i>r</i> = 0.35; <i>p</i> = 0.035), but not with WMFT-Time (<i>r</i> = 0.26; <i>p</i> = 0.120). No significant correlations were observed between CP area asymmetry or CST lesion load and any of the outcome measures.</p><p><strong>Conclusions: </strong>Our findings support FA-PLIC asymmetry as a biomarker of CST involvement, associated with the FMA and with the quality of movement during execution of functional tasks, in the chronic phase after stroke.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"630-640"},"PeriodicalIF":2.3,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145782964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}