Topics in Stroke Rehabilitation最新文献

{"title":"Effects of repetitive transcranial magnetic stimulation over the supplementary motor area on balance and postural control in stroke patients: a randomized controlled trial.","authors":"Hanhong Jiang, Wangqingyuan Wang, Saiqing Ye, Huiyan Song, Qiang Gao","doi":"10.1080/10749357.2025.2553596","DOIUrl":"https://doi.org/10.1080/10749357.2025.2553596","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the effects of 10 Hz repetitive transcranial magnetic stimulation (rTMS) targeting the supplementary motor area (SMA) on balance and postural control in patients with stroke.</p><p><strong>Methods: </strong>In this randomized controlled trial, 40 patients withbalance disorders were randomly assigned to either the transcranial magneticstimulation (TMS) group (<i>n</i> = 20) or the sham group (<i>n</i> = 20). Both groups underwent a two-week standardized physical therapy. Before each session, the TMS groupreceived 10 Hz, 1000pulses of TMS over the SMA, while the sham group receivedsham stimulation. The primary outcome was the Berg Balance Scale (BBS).Secondary outcomes included the Trunk Impairment Scale (TIS), PosturalAssessment Scale for Stroke Patients (PASS), active motor threshold (AMT) andmotor evoked potential (MEP) amplitude. Measurements were taken before andafter 10 sessions of interventions. The analysis used a 2 × 2 mixed repeatedmeasures ANOVA to assess the effects of the interventionswithin groups and between subjects.</p><p><strong>Results: </strong>There were statistically meaningful group-by-timeinteractions on the BBS (<i>p</i> = 0.001, F = 31.25), TIS (<i>p</i> = 0.002, F = 24.62) and PASS (<i>p</i> = 0.001, F = 13.02). No significant group effect orgroup-by-time interaction was detected for AMT and MEP amplitude.</p><p><strong>Conclusion: </strong>The study suggests that the applying 10 Hz rTMS over theSMA can significantly enhance balance and postural control in patients withstroke.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"1-11"},"PeriodicalIF":2.5,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of acupuncture treatment on sleep quality in post-stroke patients.","authors":"Nur Kesiktaş, Eser Kalaoğlu, Büşra Şirin Ahısha, Azad Günderci, Melek Özarslan","doi":"10.1080/10749357.2025.2553590","DOIUrl":"https://doi.org/10.1080/10749357.2025.2553590","url":null,"abstract":"<p><strong>Background: </strong>Sleep problems are significant and common complications among patients who have experienced a stroke. Acupuncture is considered a potentially effective, low-risk, and cost-efficient therapeutic option for post-stroke insomnia.</p><p><strong>Objectives: </strong>The aim of this study is to evaluate the effect of acupuncture therapy on sleep quality in patients experiencing insomnia in the early post-stroke period.</p><p><strong>Methods: </strong>In this randomized, controlled, single-blind study, 70 ischemic stroke patients undergoing inpatient rehabilitation were included. Participants were randomly assigned to either the acupuncture group, which received acupuncture alongside standard rehabilitation, or the control group, which received standard rehabilitation alone. PSQI scores were evaluated at three time points: before treatment (baseline), at the end of treatment (week 4), and 4 weeks after the end of treatment (week 8).</p><p><strong>Results: </strong>The acupuncture group showed significantly greater improvement in sleep quality compared to the control group. Significant differences were observed between the baseline PSQI scores and the PSQI scores at the 4th week in both the acupuncture and control groups (<i>p</i> < 0.001 and <i>p</i> = 0.008, respectively). The change between baseline and 8th-week PSQI scores was also significant (<i>p</i> < 0.001 for both groups). However, the decrease in PSQI scores was significantly greater in the acupuncture group compared to the control group. The addition of acupuncture therapy to standard rehabilitation resulted in a significant improvement in sleep quality. Additionally, baseline PSQI scores were found to correlate with the severity of depression.</p><p><strong>Conclusions: </strong>This study suggests that acupuncture therapy can be an effective intervention for improving sleep quality in patients with early post-stroke insomnia.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"1-12"},"PeriodicalIF":2.5,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144993283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Life after stroke: changes in sensory health and the impact on participation.","authors":"Antoine L Bailliard, Lunar Singsomphone, Nathalia Kim, Sophia Y Li, Neha Vutakuri, Hidaya Ougui, Daniella Galtes, Kimberly Hreha","doi":"10.1080/10749357.2024.2435659","DOIUrl":"10.1080/10749357.2024.2435659","url":null,"abstract":"<p><strong>Background: </strong>Research has demonstrated that adults post-stroke may experience sensory impairments across different sensory systems. There is a gap in research describing how sensory changes after stroke affect participation in health promoting activities.</p><p><strong>Objectives: </strong>The purpose of this study is to understand how changes in sensory health after stroke affect participation in meaningful activities.</p><p><strong>Methods: </strong>We adopted a qualitative phenomenological design to conduct four focus groups with ten participants: two focus groups with a cohort of adults post-stroke (<i>n</i>=5) and two focus groups with a cohort of stroke rehabilitation therapists and stroke caregivers (<i>n</i>=5). Focus group transcripts were coded using open and focused coding with NVivo software to develop themes.</p><p><strong>Results: </strong>Participants reported changes in their visual, vestibular, proprioceptive, olfactory, gustatory, tactile, and auditory systems that affected their participation in meaningful activities. Participants also reported that they experienced insufficient resources and therapies addressing their sensory health after their stroke. Analyses yielded the following themes:(1) it's hidden and invisible;(2) sensory changes affect participation and can be overwhelming; and (3) it's easy to stay inside: sensory changes negatively affect social participation.</p><p><strong>Conclusions: </strong>Adults post-stroke experience sensory changes that restrict their participation in meaningful activities including social activities; however, these changes were often missed. More research is needed to further explore the impact of changes in sensory health and understand needs regarding the development of assessment tools and intervention protocols to address the sensory health of adults post-stroke in the clinic, home, and community.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"586-594"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12183767/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Online Mood Assessment Post Stroke (O-MAPS) training: a phase II randomized-controlled trial.","authors":"Rebecca El-Helou, Brooke Ryan, Jeffrey M Rogers, Dianne L Marsden, Ann Winkler, Andrew Baillie, James Elhindi, Liz Gallagher, Ian Kneebone","doi":"10.1080/10749357.2024.2448098","DOIUrl":"10.1080/10749357.2024.2448098","url":null,"abstract":"<p><strong>Background: </strong>Anxiety and depressive disorders as well as suicidal ideas are common post stroke and early identification via routine screening is imperative for stroke survivors to access formal assessment and treatment. Currently there is a dearth of training programs available and no online mood screening training programs have been evaluated to date.</p><p><strong>Objectives: </strong>The current study aims to evaluate the Online Mood Assessment Post Stroke Training Program (OMAPS) developed in partnership with the Stroke Foundation in Australia via a phase II wait listed Randomized Control Trial.</p><p><strong>Methods: </strong>Recruitment occurred online via webinars and social media pages for stroke clinicians and enrolled participants were randomized, using REDCAP randomization software, into the immediate intervention group or wait list control (where participants waited for one week to complete the training). Participants completed a Mood Screening Self-Efficacy Questionnaire (MSEQ) and a mood screening knowledge quiz, pre and post training. Participants were followed up one month following via e-mail to determine whether they implemented the training.</p><p><strong>Results: </strong>The results indicated that participants screening knowledge quiz scores improved (<i>M</i> = 1.01, t (59) = 6.81, <i>p</i>=<0.0001, d = 1.05) and self-reported self-efficacy increased for both groups after completing the training (<i>t</i> = 8.294, <i>p</i> < 0.001). Many participants reported a change of practice following completing the training and others reported remaining barriers to implementation.</p><p><strong>Conclusions: </strong>The results of this study are promising and indicate the preliminary efficacy of the OMAPS training program in boosting stroke clinicians' self-efficacy in mood screening. Further studies should evaluate and explore other changes in clinical practices as a result of the training.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":"32 6","pages":"595-607"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144800335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive validity of obstacle-crossing test variations in identifying fallers after inpatient rehabilitation for stroke.","authors":"Prudence Plummer, Megan E Schliep, Lina Jallad, Ehsan Sinaei, Jody A Feld, Vicki S Mercer","doi":"10.1080/10749357.2024.2437327","DOIUrl":"10.1080/10749357.2024.2437327","url":null,"abstract":"<p><strong>Background: </strong>The ability to step over an obstacle is often evaluated as part of fall-risk and balance assessments. Although different obstacle-crossing tests exist, their comparative predictive validity in stroke is unknown.</p><p><strong>Objectives: </strong>To examine the predictive validity of different obstacle depths and different obstacle-crossing tests, including a novel, custom-height test and an existing \"one-size-fits-all\" obstacle test, for predicting post-stroke fallers.</p><p><strong>Methods: </strong>46 independently ambulatory adults with stroke completed a custom-height obstacle-crossing test with 3 depths (0.5-inch, 1.5-inch, 3.0-inch) and the Functional Gait Assessment (FGA) 1-3 days before hospital discharge. Falls were tracked prospectively for 3 months using fall calendars and fortnightly phone calls.</p><p><strong>Results: </strong>35% of participants fell at least once in 3 months. Test accuracy was not significantly different between obstacle depth conditions. However, the 0.5-inch obstacle depth condition demonstrated the highest sensitivity and specificity, and participants who failed were 9 times more likely to fall in the first 3 months after discharge than those who passed (95% CI 1.9, 42.1; <i>p</i> = 0.005). Performance on the obstacle item of the FGA at hospital discharge was not significantly associated with fall status at 3 months post-discharge and had a 50% floor effect.</p><p><strong>Conclusions: </strong>The ability to step over a custom-height obstacle may be a good indicator of post-stroke fall status 3 months after hospital discharge. Subtle increases in obstacle depth did not significantly alter accuracy. The \"one-size-fits-all\" obstacle test from the FGA had poor predictive validity at discharge from inpatient rehabilitation for stroke.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"631-639"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143011906","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of visual stimulation using color looming disc in Anton syndrome: a case report.","authors":"Yuji Han, Soo Jeong Han, Hunbo Shim, Jee Hyun Suh","doi":"10.1080/10749357.2024.2413269","DOIUrl":"10.1080/10749357.2024.2413269","url":null,"abstract":"<p><p><b>Objectives</b>: Anton syndrome is arare stroke syndrome that develops after damage to both occipital lobes, leading to cortical blindness and visual anosognosia. This report describes the rehabilitation course and functional progress of a 42-year-old man diagnosed with Anton syndrome.<b>Methods</b>: The patient started visual stimulation therapy using a color looming disc 5 months after Anton syndrome onset, for 30 minutes a day, 5 times a week for 4 weeks, totaling 20 sessions.<b>Results</b>: After 4 weeks of visual stimulation therapy using color-looming discs, reading tests for consonants, numbers, words, and colors and the latency of the P100 of Visual Evoked Potential showed improvement. Additionally, improvements were noted in the Modified Barthel Index and Mini-Mental State Examination scores related to visual function.<b>Conclusions</b>: This case illustrates the effectiveness of visual stimulation therapy using color-looming discs and its potential to achieve positive outcomes.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"662-668"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142381702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of the relationship between lower limb orthosis user satisfaction and quality of life and functionality in stroke patients: a cross-sectional study.","authors":"Ahmet Veli İçoglu, Sulenur Yildiz","doi":"10.1080/10749357.2024.2435199","DOIUrl":"10.1080/10749357.2024.2435199","url":null,"abstract":"<p><strong>Background: </strong>Orthosis satisfaction may be an important parameter that increases orthosis usage and reveals orthosis' positive effect on rehabilitation.</p><p><strong>Objectives: </strong>To investigate the relationship between lower limb orthosis user satisfaction and quality of life (QOL) and functionality in stroke patients.</p><p><strong>Methods: </strong>Forty-four stroke patients with a mean age of 56.91 ± 14.08 years were included. Orthosis user satisfaction was evaluated using the Orthotics and Prosthetics Users' Survey (OPUS). QOL was assessed using the Stroke-Specific Quality of Life Scale (SS-QOL). Lastly, functional status was evaluated using the Fugl - Meyer Assessment of Lower Extremity (FMA-LE) and Timed Up and Go Test (TUGT).</p><p><strong>Results: </strong>The relationships were found between the OPUS total satisfaction and SS-QOL-selfcare (<i>r</i> = -0.412, <i>p</i> = 0.005), and upper extremity (<i>r</i> = -0.401, <i>p</i> = 0.007); OPUS device satisfaction and SS-QOL-selfcare (<i>r</i> = -0.484, <i>p</i> < 0.001) and upper extremity function (<i>r</i> = -0.379, <i>p</i> = 0.011); and OPUS service satisfaction and FMA-LE (<i>r</i> = 0.880, <i>p</i> = 0.001). There was no relationship between the OPUS total satisfaction, service satisfaction, and daily orthosis use time (<i>p</i> > 0.05). While participants' QOL and lower extremity functionality were generally at low, those with better functional status had lower orthosis satisfaction because it made ambulation at home difficult.</p><p><strong>Conclusion: </strong>Taking patient opinions into account in the orthotic design process will help to eliminate the problems related to comfort and orthotic wear that might affect orthotic satisfaction. The production of more comfortable orthoses might positively affect individuals' use of orthoses and satisfaction. This outcome may be a good starting point for prospective studies.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"645-651"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142772634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Establishing minimal clinically important difference of modified dynamic gait index in people with subacute stroke.","authors":"Fabiola Giovanna Mestanza Mattos, Thomas Bowman, Cristina Allera Longo, Serena Bocini, Michele Gennuso, Francesca Marazzini, Francesco Giuseppe Materazzi, Elisa Pelosin, Martina Putzolu, Silvia Salvalaggio, Andrea Turolla, Susanna Mezzarobba, Davide Cattaneo","doi":"10.1080/10749357.2024.2437326","DOIUrl":"10.1080/10749357.2024.2437326","url":null,"abstract":"<p><strong>Background: </strong>People with stroke (PwST) often have significant balance limitations, making it crucial to focus rehabilitation on improving mobility and reducing the risk of falls. The Modified Dynamic Gait Index (MDGI) is recommended for measuring balance in various neurological conditions, but a minimal clinically important difference (MCID) score specific to PwST is missing.</p><p><strong>Objectives: </strong>To calculate the MCID of the MDGI in PwST during the subacute phase.</p><p><strong>Methods: </strong>This study is a secondary analysis utilizing data from an observational longitudinal study. Forty-four PwST met the inclusion criteria such as age > 18 years, diagnosis of cerebral infarction or hemorrhage within 180 days, and Mini-Mental State Examination ≥ 21. Participants received at least 10 sessions of tailored physiotherapy to improve balance and gait. Balance was assessed using the MDGI and the Activities-specific Balance Confidence Scale (ABC) before and after intervention. The MCID was determined using an anchor-based approach, with the ABC serving as the anchor.</p><p><strong>Results: </strong>Statistically significant improvements were observed in mean MDGI change scores of 19.5(14.6) points, (<i>p</i> < 0.01) and ABC change scores of 27.1(25.3) points, (<i>p</i> < 0.01). The MCID for the MDGI total score was identified as 17.5 points. The Spearman correlation between MDGI and ABC change scores was 0.51 (<i>p</i> < 0.01).</p><p><strong>Conclusions: </strong>An MCID of 17.5 points for the MDGI total score indicates clinically meaningful improvements in balance and gait performance in subacute PwST undergoing rehabilitation. This value provides a robust metric for evaluating the efficacy of balance-related interventions in this population.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"640-644"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142955606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effectiveness of core stability exercises on functional outcomes in early subacute stroke recovery: a randomized controlled trial.","authors":"Rosa Cabanas-Valdés, Lídia Boix-Sala, Marta Ferrer-Solà, Montserrat Grau-Pellicer, Nuria Gracia-Pí, Neus Torrella-Vivó, Marta Morales-Zafra, Eric Esteve-Hernández, Juan-Antonio Guzmán-Bernal, Fernanda-Maria Caballero-Gómez, Begoña Molina-Hervás, Samira González-Hoelling, Ana Lobato-Bonilla, Carlos López-de-Celis, Esther Cánovas, Gerard Urrútia","doi":"10.1080/10749357.2024.2439712","DOIUrl":"10.1080/10749357.2024.2439712","url":null,"abstract":"<p><strong>Background: </strong>The core is important in providing local strength and balance and is central to almost all kinetic chains of daily activities.</p><p><strong>Objective: </strong>This study aimed to assess the effectiveness of additional Core Stability Exercises (CSE) to conventional physiotherapy (CP) versus CP alone to improve dynamic sitting balance, coordination, trunk function, and stepping (gait) as a primary outcome and functional sitting balance, postural control, standing balance and fall risk, lower limb spasticity, activities of daily living, degree of disability, and quality of life for early subacute stroke recovery.</p><p><strong>Methods: </strong>A multicentre parallel, randomized, controlled, assessor-blinded trial was conducted. Eighty-seven early stroke survivors initiated (≤30 days) were divided into two groups. Experimental group (EG) performed CSE in addition to CP and the control group (CG) performed CP alone for 5-day/week for 5-week. Outcomes were assessed at the beginning and end of the intervention (5-week) and follow-up (12-week). Quality of life was assessed at 5-week and 12- week. Variables were analyzed using a repeated-measures analysis of variance (ANOVA), with Bonferroni's post-hoc test. All statistical tests were performed for 0.05 significance level and 95% confidence interval.</p><p><strong>Results: </strong>Eighty-three individuals were analyzed 40 in the EG and 43 in the CG. Differences between groups were shown favoring EG regarding dynamic sitting balance, trunk coordination/function (Spanish-Trunk Impairment Scale), lower limb spasticity (modified-Ashworth Scale) and balance (Spanish-Postural Assessment Scale). No differences were observed for the other outcomes.</p><p><strong>Conclusions: </strong>CSE in addition to CP improves dynamic sitting balance, trunk coordination/function, lower-limb spasticity, and balance in early recovery post-stroke.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"618-630"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142915636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of intermittent theta burst stimulation (iTBS) for managing post-stroke dysphagia: systematic review and meta-analysis.","authors":"Syed Muhammad Mehdi Zaidi, Mustafa Hassan Alvi, Syed Ashad Ahmed Fatmi, Laraib Abbasi, Ammar Hayat, Qunoot Irfan, Sana Zehra, Zainab Abbas, Syed Muhammad Askari Zaidi","doi":"10.1080/10749357.2024.2437325","DOIUrl":"10.1080/10749357.2024.2437325","url":null,"abstract":"<p><strong>Background: </strong>Post-Stroke Dysphagia (PSD) is a common complication that significantly affects the quality of life and health outcomes of stroke survivors. Traditional treatments often have limitations, necessitating the exploration of new therapeutic approaches. This systematic review and meta-analysis aimed to evaluate the efficacy of intermittent Theta Burst Stimulation (iTBS) as an innovative treatment for PSD.</p><p><strong>Methods: </strong>Following the PRISMA guidelines, a comprehensive literature search was conducted in PubMed, Embase, and Cochrane Library up to July 2024. Studies included were randomized controlled trials (RCTs) involving stroke patients with confirmed dysphagia, comparing iTBS to control treatments. Data extraction and quality assessment were performed independently by two reviewers using the Cochrane RoB 2 tool. Primary outcomes were changes in the Penetration-Aspiration Scale (PAS) and Swallowing Severity Scale (SSA). Meta-analyses were conducted using Review Manager (RevMan) 5.4.</p><p><strong>Results: </strong>Four RCTs with a total of 199 participants were included. iTBS significantly improved SSA (MD = -3.26, 95% CI [-4.66, -1.86], <i>p</i> < 0.001) and PAS (MD = -1.67, 95% CI [-2.49, -0.86], <i>p</i> < 0.001) immediately after treatment compared to sham stimulation. No significant adverse events were reported.</p><p><strong>Conclusion: </strong>iTBS appears to have a positive immediate effect on improving swallowing function and reducing aspiration risk in PSD patients compared to sham stimulation. However, these effects may not persist in the long term, and further large-scale RCTs are needed to confirm these findings and establish standardized treatment protocols.</p>","PeriodicalId":23164,"journal":{"name":"Topics in Stroke Rehabilitation","volume":" ","pages":"652-661"},"PeriodicalIF":2.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142795128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}