Tobacco ControlPub Date : 2026-05-07DOI: 10.1136/tc-2024-058915
Jinho Lee, Masoud Afshar, Wei-Chung Su, Inkyu Han
{"title":"Effect of electronic cigarette atomising power and flavour on aerosol size-segregated metal concentration and inhalation risk.","authors":"Jinho Lee, Masoud Afshar, Wei-Chung Su, Inkyu Han","doi":"10.1136/tc-2024-058915","DOIUrl":"10.1136/tc-2024-058915","url":null,"abstract":"<p><strong>Introduction: </strong>Although numerous studies have estimated the inhalation dose of metals emitted from electronic cigarettes (e-cigs), the impact of factors including aerosol size and the atomising power of e-cig aerosols on estimating the inhalation dose of metals remains underexplored. A comprehensive understanding of these determinants is essential to assess the health risks associated with inhaling e-cig aerosols, which may contain potentially harmful metals.</p><p><strong>Objectives: </strong>The aim of this study is to elucidate the mass and inhalation doses of potentially harmful metals in e-cig aerosols by different particle size and their association with the various atomising powers of e-cig devices and flavours.</p><p><strong>Methods: </strong>Size-segregated e-cig aerosols were generated and collected in a exposure chamber, using an 11-stage cascade impactor for the analyses of aerosol mass and metals. The metal deposition dose in the human respiratory tract was calculated using a mathematical respiratory deposition estimation model and metal mass concentration by the size of aerosols.</p><p><strong>Results: </strong>In this study, the results showed that neither an increase in atomising power (from 5 to 20 W) nor e-cig flavours resulted in a significant increase in a metal deposition in the respiratory tracts. Although the factors did not significantly affect the calculated respiratory deposition of harmful metals under typical e-cig usage assumption, the estimated hazard index exceeded 1.0.</p><p><strong>Conclusion: </strong>The calculated health risks suggest substantial risks of inhalation of metal aerosols from e-cig use.</p>","PeriodicalId":23145,"journal":{"name":"Tobacco Control","volume":" ","pages":"289-297"},"PeriodicalIF":4.7,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12260031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143012196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tobacco ControlPub Date : 2026-05-07DOI: 10.1136/tc-2024-058798
Javad Heshmati, Avinash Pandey, Joseph Benjamen, Muhammad Furqan, Muhammad Salman, Sarah Visintini, Kerri-Anne Mullen, Gordon Guyatt, Andrew L Pipe, Hassan Mir
{"title":"Vaping cessation interventions: a systematic review and meta-analysis.","authors":"Javad Heshmati, Avinash Pandey, Joseph Benjamen, Muhammad Furqan, Muhammad Salman, Sarah Visintini, Kerri-Anne Mullen, Gordon Guyatt, Andrew L Pipe, Hassan Mir","doi":"10.1136/tc-2024-058798","DOIUrl":"10.1136/tc-2024-058798","url":null,"abstract":"<p><strong>Objective: </strong>Electronic nicotine delivery systems (ENDS), such as e-cigarettes, have surged in popularity. While long-term risks remain unclear, known dangers include nicotine addiction, E-cigarette or Vaping Use-Associated Lung Injury and potential extrapulmonary effects on the heart, immune system and neurodevelopment. Addressing ENDS addiction may require strategies akin to smoking cessation. However, evidence is lacking; there are no currently approved vaping-cessation aids. The objective of this review is to summarise the available literature addressing interventions for vaping cessation.</p><p><strong>Data sources and study selection: </strong>A librarian-assisted search was conducted in MEDLINE, Embase and Scopus, as well as preprints in Europe PMC, Open Science Framework, and the grey literature searches until January 2024. Six included studies used self-report methods to determine the abstinence rate, while one study used cotinine-level-verified self-reported abstinence. We included randomised controlled trials (RCTs) that examine 'rates of vaping cessation' outcomes. An intention-to-treat approach was used for data extraction, and random-effects meta-analyses models were applied.</p><p><strong>Data synthesis: </strong>Seven RCTs were included, which studied pharmacological therapy, digital interventions and/or educational content. The primary meta-analyses demonstrated a statistically significant increase in the odds of achieving 7-day point prevalence abstinence (PPA) (OR 1.52, 95% CI 1.15 to 2.01, number of participants=3244, moderate-certainty) and continuous abstinence (OR 2.71, 95% CI 1.31 to 5.61, number of participants=164, low-certainty) following intervention. A non-significant increase in odds was noted at 30-day PPA (OR 1.32, 95% CI 0.72 to 2.42, number of participants=1994, very low certainty).</p><p><strong>Conclusions: </strong>Vaping cessation interventions increase 7-day PPA rates at 1-12 months follow-up and this was consistent across prespecified subgroup analyses of the intervention type, outcome and duration of follow-up. More high-quality studies with reproducible findings are needed to enhance the certainty of the evidence and guide clinical interventions.</p><p><strong>Prospero registration number: </strong>CRD42022383670.</p>","PeriodicalId":23145,"journal":{"name":"Tobacco Control","volume":" ","pages":"382-390"},"PeriodicalIF":4.7,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tobacco ControlPub Date : 2026-05-07DOI: 10.1136/tc-2024-058795
Ingrid Allagbé, Joël Ménard, Anne-Laurence Le Faou
{"title":"Characteristics of users of French smoking cessation services from 2004 to 2018.","authors":"Ingrid Allagbé, Joël Ménard, Anne-Laurence Le Faou","doi":"10.1136/tc-2024-058795","DOIUrl":"10.1136/tc-2024-058795","url":null,"abstract":"<p><strong>Objectives: </strong>We investigated changes in the profile of persons who smoke (PWS) seeking assistance from smoking cessation services (SCS) in France between 2004 and 2018, aligning with national policies.</p><p><strong>Methods: </strong>A prospective study of 131 280 adult PWS was conducted across three periods: 2004-2008 (during a 42% increase in tobacco prices), 2009-2013 (following a tobacco sales ban to minors) and 2014-2018 (marking the first national antismoking policy). Sociodemographic and medical characteristics, smoking behaviours and prescribed cessation medications were analysed cross-sectionally at the first consultation.</p><p><strong>Results: </strong>Between 2004-2008 and 2014-2018, the mean age of SCS attendees increased from 44 to 47 years (p<0.001). Concurrently, the proportion of PWS without a school diploma rose from 19% to 22%, and unemployed PWS from 13% to 22% (both p<0.001). Smoking-related cancer prevalence doubled from 3% to 6% (p<0.001). The proportion of PWS with no prior quit attempts increased from 31% in 2004-2008 to 35% in 2014-2018 (p<0.001). There was also a notable decline in those attending SCS on a personal initiative, dropping from 45% to 35% (p<0.001). Mean number of cigarettes smoked daily was stable at 23 between 2004 and 2018. Combination nicotine replacement therapy remained the most prescribed cessation medication, accounting for 44% of treatments during this period.</p><p><strong>Conclusions: </strong>Despite tobacco control efforts between 2004 and 2018, challenges persist in reducing smoking behaviours in France. Increased SCS utilisation among older adults and individuals with lower socioeconomic status underscores the importance of enhancing SCS availability in France to support the various profiles of PWS.</p>","PeriodicalId":23145,"journal":{"name":"Tobacco Control","volume":" ","pages":"320-330"},"PeriodicalIF":4.7,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tobacco ControlPub Date : 2026-05-07DOI: 10.1136/tc-2024-059215
Reiner Hanewinkel, Julia Hansen
{"title":"Adolescent cigarette and e-cigarette use after the rise of disposable e-cigarettes: interrupted time series study in Germany 2016-2024.","authors":"Reiner Hanewinkel, Julia Hansen","doi":"10.1136/tc-2024-059215","DOIUrl":"10.1136/tc-2024-059215","url":null,"abstract":"","PeriodicalId":23145,"journal":{"name":"Tobacco Control","volume":" ","pages":"415-416"},"PeriodicalIF":4.7,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143634531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tobacco ControlPub Date : 2026-05-07DOI: 10.1136/tc-2024-058958
Luke B Wilson, Colin Angus, Alan Brennan, Duncan Gillespie, Niamh K Shortt, Helena Tunstall, Roberto Valiente, Jamie Pearce
{"title":"Quantile regression of tobacco tax pass-through in the UK 2017-2021: how have manufacturers passed through tax changes for different tobacco products in small retailers? Analysis at the national level and by neighbourhood of deprivation.","authors":"Luke B Wilson, Colin Angus, Alan Brennan, Duncan Gillespie, Niamh K Shortt, Helena Tunstall, Roberto Valiente, Jamie Pearce","doi":"10.1136/tc-2024-058958","DOIUrl":"10.1136/tc-2024-058958","url":null,"abstract":"<p><strong>Background: </strong>The effectiveness of tax increases in reducing tobacco consumption relies on the tobacco retailers and producers passing on increases to consumers (tax pass-through). Previous UK research on supermarkets found heterogeneous levels of tax pass-through across the market segments and price distribution of tobacco products. This study uses data from small retailers across the UK to assess whether recent tax changes have been passed on to consumers and if this varies across the price distribution, between countries of the UK and by neighbourhood deprivation.</p><p><strong>Methods: </strong>We use panel data quantile regression analysis of tobacco sales in small retailers in the UK from March 2017 to December 2021 combined with UK tax rates and store-level index of multiple deprivation (IMD). We calculated the rate of tax pass-through for factory-made cigarettes (FM) and roll-your-own tobacco (RYO).</p><p><strong>Results: </strong>Following increases in the duty payable on tobacco, we find evidence of overshifting across the entire price distribution for FM and RYO. For England, Scotland and Wales, the rate of the overshift in tax increased with product price. For Scotland, we find that stores in the least deprived IMD pass-through taxes at a higher rate.</p><p><strong>Conclusions: </strong>Our evidence shows heterogeneous levels of tax pass-through by price, region and level of deprivation. The findings emphasise the importance of understanding the pricing strategies of the tobacco industry (TI) and how these vary across the UK to develop robust approaches to mitigate the pricing strategies of the TI.</p>","PeriodicalId":23145,"journal":{"name":"Tobacco Control","volume":" ","pages":"298-306"},"PeriodicalIF":4.7,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143029635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tobacco ControlPub Date : 2026-05-07DOI: 10.1136/tc-2024-059243
Sophie Braznell
{"title":"IQOS-marketing a tobacco product in the UK.","authors":"Sophie Braznell","doi":"10.1136/tc-2024-059243","DOIUrl":"10.1136/tc-2024-059243","url":null,"abstract":"","PeriodicalId":23145,"journal":{"name":"Tobacco Control","volume":" ","pages":"419-420"},"PeriodicalIF":4.7,"publicationDate":"2026-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144544975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tobacco ControlPub Date : 2026-05-06DOI: 10.1136/tc-2025-059702
Alessia Turina, Alice Passoni, Valentina Liboni, Walther N Klerx, Reinskje Talhout, Hans Cremers, Max Van Alphen, Benoît Labarbe, Enrico Davoli
{"title":"Future-proofing chemical profiling of tobacco and nicotine products: standardised non-targeted analysis (NTA) of e-liquid flavour profiles for monitoring and regulation purposes.","authors":"Alessia Turina, Alice Passoni, Valentina Liboni, Walther N Klerx, Reinskje Talhout, Hans Cremers, Max Van Alphen, Benoît Labarbe, Enrico Davoli","doi":"10.1136/tc-2025-059702","DOIUrl":"https://doi.org/10.1136/tc-2025-059702","url":null,"abstract":"<p><strong>Background: </strong>The tobacco industry increasingly targets youth through products such as electronic cigarettes and heated tobacco devices. In Italy, 9.6% of children aged 11-13 use tobacco and nicotine products, with e-cigarettes being the most prevalent, reflecting a global trend. Articles 9 and 10 of the WHO Framework Convention on Tobacco Control mandate testing and disclosure of ingredients, including flavours, highlighting the need for standardised analytical methods.</p><p><strong>Objectives: </strong>To develop and validate a standardised non-targeted analysis (NTA) method for the compositional assessment of e-cigarette liquids.</p><p><strong>Methods: </strong>A gas chromatography-mass spectrometry based NTA method was developed and validated through an interlaboratory study involving 21 laboratories worldwide. The method enables direct analysis of e-liquids and semi-quantitative evaluation of detected compounds.</p><p><strong>Results: </strong>The method was applied to 23 commercial e-liquids from different WHO regions, identifying flavouring agents, allergens, and potential skin, eye, and respiratory irritants. Predominant flavour profiles included candy-sweet, fruity, and cooling compounds, with regional variability observed. The method demonstrated robustness and reproducibility across laboratories, including those with limited instrumentation.</p><p><strong>Conclusions: </strong>This standardised NTA approach, now adopted as a WHO Standard Operating Procedure, provides a reliable tool for regulatory monitoring, supporting compliance, detecting undeclared substances, and strengthening flavour-related regulations globally.</p>","PeriodicalId":23145,"journal":{"name":"Tobacco Control","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147842708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tobacco ControlPub Date : 2026-05-05DOI: 10.1136/tc-2025-059919
Elizabeth K Do, Joslynn A Watkins, Madison L Iskra, Kristiann Koris, Sarah Cha, Amanda L Graham, Eric K Soule, Elizabeth C Hair
{"title":"E-cigarette use in vehicles: factors associated with secondhand exposure and behaviour from a US young adult sample in 2024.","authors":"Elizabeth K Do, Joslynn A Watkins, Madison L Iskra, Kristiann Koris, Sarah Cha, Amanda L Graham, Eric K Soule, Elizabeth C Hair","doi":"10.1136/tc-2025-059919","DOIUrl":"https://doi.org/10.1136/tc-2025-059919","url":null,"abstract":"<p><strong>Background: </strong>This study investigates factors associated with electronic cigarette (e-cigarette) use and secondhand exposure in vehicles among US youth and young adults.</p><p><strong>Methods: </strong>Data were collected from an online panel survey of individuals (N=3482, aged 15-25 years) from July to December 2024. Analyses included those who reported using any tobacco product in the past 30 days and answered items measuring exposure to (N=2600) and/or use of e-cigarettes in vehicles (N=2366). Logistic regression models assessed predictors of e-cigarette use and exposure in vehicles, including demographic, psychosocial and tobacco use characteristics.</p><p><strong>Results: </strong>Among all participants, 67.1% reported e-cigarette use in the past 30 days. Of those reporting current e-cigarette use (N=2336), 60.6% reported using their e-cigarette/vape while travelling by car in the past 30 days. Of those who answered the question measuring exposure to e-cigarette use in vehicles (N=2600), 69.3% reported being in a vehicle where someone was using e-cigarettes. Higher nicotine dependence and residence in small metro and non-metro areas were associated with greater odds of using e-cigarettes in vehicles. Just meeting basic expenses or meeting needs with a little left, household tobacco use and residence in small metro areas were associated with greater odds of secondhand e-cigarette exposure.</p><p><strong>Discussion: </strong>Public health interventions should place a strong focus on education and increasing public awareness of the health consequences of e-cigarette use in vehicles to protect bystanders from secondhand e-cigarette exposure.</p>","PeriodicalId":23145,"journal":{"name":"Tobacco Control","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147842436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tobacco ControlPub Date : 2026-05-04DOI: 10.1136/tc-2025-059589
Megan C Diaz, Adrian Bertrand, Elizabeth C Hair
{"title":"US retail sales of total kilogrammes of nicotine in oral nicotine pouches and e-cigarettes continue to increase.","authors":"Megan C Diaz, Adrian Bertrand, Elizabeth C Hair","doi":"10.1136/tc-2025-059589","DOIUrl":"10.1136/tc-2025-059589","url":null,"abstract":"","PeriodicalId":23145,"journal":{"name":"Tobacco Control","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145769278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"From vision to action: a framework to assess readiness for the tobacco endgame.","authors":"Ariadna Feliu, Cristina Martinez, Constantine Vardavas, Esteve Fernández, Filippos T Filippidis","doi":"10.1136/tc-2025-059920","DOIUrl":"https://doi.org/10.1136/tc-2025-059920","url":null,"abstract":"<p><strong>Background: </strong>Tobacco endgame strategies aim to reduce smoking prevalence to minimal levels (<5%) through measures that expand traditional tobacco control approaches. Although some countries have set endgame targets, most still report prevalence rates >15%, and practical guidance on how to assess readiness for endgame implementation remains limited. This study aims to synthetise the key determinants of jurisdictions' readiness for tobacco endgame and proposes a self-assessment tool to evaluate it.</p><p><strong>Methods: </strong>A narrative review of peer-reviewed and grey literature published between January 2010 and September 2025 was conducted. Publications were identified through targeted searches of academic databases and relevant organisational websites. A thematic synthesis of evidence on political, social and structural determinants of readiness was undertaken to identify recurring domains, which were later used to inform the development of a self-assessment tool.</p><p><strong>Results: </strong>Nine readiness domains were identified: relatively low smoking prevalence; advanced implementation of WHO Framework Convention on Tobacco Control measures; robust enforcement infrastructure; social denormalisation of smoking; broad public understanding and support for ending tobacco use; a positive political climate and strong political will and leadership; a cohesive tobacco control community and civil society; minimal tobacco industry interference with strong protective mechanisms; and sufficient resources to implement tobacco endgame action plan. These domains guided the development of an evidence-informed self-assessment tool to help jurisdictions evaluate readiness, identify gaps and prioritise strategic actions.</p><p><strong>Conclusion: </strong>The Assessment of Readiness for Tobacco Endgame tool offers an evidence-informed framework to assess tobacco endgame readiness, helping jurisdictions assess capacities, identify gaps and guide strategic decision-making.</p>","PeriodicalId":23145,"journal":{"name":"Tobacco Control","volume":" ","pages":""},"PeriodicalIF":4.7,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147842717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}