The Korean Journal of Helicobacter and Upper Gastrointestinal Research最新文献_第4页

Comparison of Helicobacter pylori Eradication Rates Using Standard Triple Therapy and Sequential Therapy 采用标准三联疗法和序贯疗法的幽门螺杆菌根除率比较

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-12-10 DOI: 10.7704/kjhugr.2023.0042

Yuria Kim, J. Ahn, H. Jung, J. Noh, H. Na, Kee Wook Jung, Jeong Hoon Lee, D. Kim, K. Choi, H. Song, G. Lee

{"title":"Comparison of Helicobacter pylori Eradication Rates Using Standard Triple Therapy and Sequential Therapy","authors":"Yuria Kim, J. Ahn, H. Jung, J. Noh, H. Na, Kee Wook Jung, Jeong Hoon Lee, D. Kim, K. Choi, H. Song, G. Lee","doi":"10.7704/kjhugr.2023.0042","DOIUrl":"https://doi.org/10.7704/kjhugr.2023.0042","url":null,"abstract":"Objectives: The incidence of treatment failures following standard triple therapy (STT) for Helicobacter pylori eradication (HPE) has reached an unacceptable level. Sequential therapy (SQ) has emerged as a promising approach to counteract the escalation of antibiotic resistance. In this study, we used a chronological cohort dataset to conduct a comparative analysis of the eradication rates, compliance, and adverse events associated with the 7-day STT and SQ.Methods: A total of 789 patients underwent HPE treatment at Asan Medical Center between July 2013 and August 2017. Among them, 378 received a 7-day STT and 411 received a 10-day SQ. Baseline clinical data and treatment parameters were compared between the two treatment groups.Results: SQ demonstrated an eradication rate of 84.7% (348/411), which was superior to that of the 7-day STT (74.1%; p<0.001). The incidence of adverse events was also higher in the SQ group than in the STT group (17.5% vs. 11.1%; p=0.01). Nonetheless, treatment compliance was not significantly different between the groups (98.1% [SQ] vs. 96.8% [STT]; p=0.38). Among the patients undergoing second-line eradication, the SQ group displayed a lower eradication rate than the STT group (77.8% vs. 92.4%; p=0.028). Notably, the overall eradication rate did not differ significantly between the two groups (98.3% [STT] vs. 97.4% [SQ]; p=0.56).Conclusions: SQ exhibited superior efficacy compared with the 7-day STT as a first-line H. pylori treatment. Thus, SQ holds potential to serve as the replacement for the 7-day STT in treatment-naïve patients.","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":"13 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138585300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Does Types of 23S-Ribosomal RNA Point Mutations Affect Helicobacter pylori Eradication Rate in Clarithromycin-Based Triple Therapy? 23S-Ribosomal RNA 点突变类型会影响克拉霉素三联疗法的幽门螺旋杆菌根除率吗？

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-12-10 DOI: 10.7704/kjhugr.2023.0062

Da Hyun Jung

引用次数: 0

[Possibility of Endoscopic Resection in Localized Gastric Mucosa-associated Lymphoid Tissue Lymphoma]. 内镜下切除胃黏膜相关淋巴组织淋巴瘤的可能性

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-09-01 Epub Date: 2023-09-08 DOI: 10.7704/kjhugr.2023.0033

Sun Hyung Kang

引用次数: 0

[Precision Medicine for Gastric Cancer: Applicability from the Perspective of Helicobacter pylori Infection]. 胃癌精准医疗:幽门螺杆菌感染视角下的适用性

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-09-01 Epub Date: 2023-09-08 DOI: 10.7704/kjhugr.2023.0030

Ah Cheon Park, Sung Eun Kim

引用次数: 0

[Dysphagia Secondary to Vocal Cord Paralysis: A Case Report]. 声带麻痹继发吞咽困难1例报告

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-09-01 Epub Date: 2023-09-08 DOI: 10.7704/kjhugr.2023.0031

Oong Hee Shin, Joon Sung Kim, Byung-Wook Kim

引用次数: 0

[Gastric Cancer of the Cardia Detected on Screening Endoscopy]. 内镜筛查贲门癌症

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-09-01 Epub Date: 2023-09-08 DOI: 10.7704/kjhugr.2023.0035

Seung Joo Kang

引用次数: 0

Endoscopic Submucosal Dissection for Treatment of Localized Gastric Mucosa-associated Lymphoid Tissue Lymphoma: A Case Series. 内镜下粘膜剥离治疗局部胃粘膜相关淋巴组织淋巴瘤:一个病例系列

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-09-01 Epub Date: 2023-08-30 DOI: 10.7704/kjhugr.2023.0025

Jun-Young Seo, Kee Don Choi, In Hye Song, Young Soo Park, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Kee Wook Jung, Do Hoon Kim, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung

{"title":"Endoscopic Submucosal Dissection for Treatment of Localized Gastric Mucosa-associated Lymphoid Tissue Lymphoma: A Case Series.","authors":"Jun-Young Seo, Kee Don Choi, In Hye Song, Young Soo Park, Hee Kyong Na, Ji Yong Ahn, Jeong Hoon Lee, Kee Wook Jung, Do Hoon Kim, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung","doi":"10.7704/kjhugr.2023.0025","DOIUrl":"10.7704/kjhugr.2023.0025","url":null,"abstract":"Background/aims: The treatment for gastric mucosa-associated lymphoid tissue lymphoma (MALToma) generally involves eradication of Helicobacter pylori. However, MALToma lesions may recur even without H. pylori re-infection. Furthermore, the remission rate of H. pylori-negative MALToma after eradication is low. Therefore, herein, we report on endoscopic submucosal dissection (ESD) as a treatment strategy for gastric MALToma.Methods: We retrospectively reviewed the data of all patients of gastric MALToma who underwent endoscopic resection at our institution between January 2000 and December 2021. Clinical remission was defined as complete histological remission or probable minimal residual disease according to the GELA grading system for post-treatment evaluation of gastric MALToma.Results: Six patients with gastric MALToma underwent ESD. Two patients were diagnosed with gastric MALToma, which improved after eradication treatment and relapsed approximately 36 and 41 months later, respectively. These patients had singular lesions localized to the mucosa and did not experience H. pylori re-infection. The lesions were successfully removed via ESD. The remaining four patients had H. pylori-negative gastric MALToma. These patients also had single, localized lesions that were removed via ESD. All the patients remained in clinical remission until the final follow-up.Conclusions: ESD is a safe and effective intervention for H. pylori-negative gastric MALToma when the lesion is single and confined to the mucosal layer.","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":" ","pages":"188-196"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967490/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49081723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary Esophageal Mucosa-associated Lymphoid Tissue Lymphoma: A Rare Case Report and Review of Other Published Data. 原发性食管黏膜相关淋巴组织淋巴瘤:一例罕见病例报告和其他已发表资料的回顾

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-09-01 Epub Date: 2023-08-30 DOI: 10.7704/kjhugr.2023.0026

Ji Hea Bang, Jin Hyong Kang, Seung Han Kim, Jong Jae Park, Beom Jae Lee, Moon Kyung Joo, Tae Sung Jeon

{"title":"Primary Esophageal Mucosa-associated Lymphoid Tissue Lymphoma: A Rare Case Report and Review of Other Published Data.","authors":"Ji Hea Bang, Jin Hyong Kang, Seung Han Kim, Jong Jae Park, Beom Jae Lee, Moon Kyung Joo, Tae Sung Jeon","doi":"10.7704/kjhugr.2023.0026","DOIUrl":"10.7704/kjhugr.2023.0026","url":null,"abstract":"The gastrointestinal tract is the most common extranodal site for lymphomas, and mucosa-associated lymphoid tissue lymphoma is the second most common histological lymphoma subtype. However, primary esophageal mucosa-associated lymphoid tissue lymphomas are extremely rare. Few such cases are documented, and the reports demonstrate inconsistent diagnostic and therapeutic strategies. Herein, a 54-year-old man was referred to our hospital for treatment of dysphagia. Esophagogastroduodenoscopy revealed a large, horseshoe-shaped subepithelial mass in the upper esophagus. Endoscopic ultrasonography and computed tomography revealed that the mass was well-demarcated and confined to the muscularis mucosa, with no abnormalities in other organs or lymph nodes. The mass was presumptively diagnosed as benign, and the patient underwent endoscopic mucosal dissection for pathological confirmation and symptom relief. Pathological examination of the dissection specimen revealed that it was a primary esophageal mucosa-associated lymphoid tissue lymphoma. As the patient had an elevated immunoglobulin G level and Helicobacter pylori infection, we administered adjuvant eradication therapy. The patient remains under surveillance and is free of lymphoma recurrence 36 months postoperatively. This case report demonstrates that endoscopic resection and H. pylori eradication are effective treatment strategies for early-stage esophageal mucosa-associated lymphoid tissue lymphoma.","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":" ","pages":"207-213"},"PeriodicalIF":0.0,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967450/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48175416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Optimal Use of Proton Pump Inhibitors and Potassium-competitive Acid Blockers]. 质子泵抑制剂和钾竞争酸阻滞剂的最佳使用

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-09-01 Epub Date: 2023-09-08 DOI: 10.7704/kjhugr.2023.0034

Jong Kyu Park

引用次数: 0

Antibiotic Resistance and Helicobacter pylori Eradication Therapy. 抗生素耐药性与幽门螺杆菌根除治疗

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2023-09-01 Epub Date: 2023-09-08 DOI: 10.7704/kjhugr.2023.0044

Younghee Choe

引用次数: 0