The Korean Journal of Helicobacter and Upper Gastrointestinal Research最新文献

A Rare Case of Signet Ring Cell Carcinoma Arising on Duodenal Brunner’s Gland Hyperplasia Successfully Treated Via Endoscopic Resection 一例罕见的十二指肠布鲁纳氏腺增生引发的印戒细胞癌，经内镜下切除术成功治愈

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2024-06-10 DOI: 10.7704/kjhugr.2024.0014

Hae Rin Lee, B. Lee, Kyung Bin Kim, Gwang Ha Kim, M. Lee, Dong Chan Joo

引用次数: 0

What Is the Optimal Drug Regimen for Helicobacter pylori Eradication Therapy? 根除幽门螺旋杆菌疗法的最佳用药方案是什么？

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2024-06-10 DOI: 10.7704/kjhugr.2024.0022

Ji Hyun Kim, Sung Chul Park

引用次数: 0

Current Status and Future Perspectives of Tegoprazan-Based Helicobacter pylori Eradication Therapy 基于替戈普拉赞的幽门螺杆菌根除疗法的现状与未来展望

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2024-06-10 DOI: 10.7704/kjhugr.2024.0023

J. Noh

引用次数: 0

Successful Endoscopic Vacuum-Assisted Closure Therapy for Esophageal Perforation: A Case Report 食管穿孔的成功内镜真空辅助闭合疗法：病例报告

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2024-06-10 DOI: 10.7704/kjhugr.2024.0025

Jung Huh, Jinsun Yang, Seung Joo Kang, Hyoun Woo Kang, Hyeon Jong Moon, Su Hwan Kim, Bokyung Kim, Ji Won Kim, Kooklae Lee, Y. Seong, K.-W. Kim

{"title":"Successful Endoscopic Vacuum-Assisted Closure Therapy for Esophageal Perforation: A Case Report","authors":"Jung Huh, Jinsun Yang, Seung Joo Kang, Hyoun Woo Kang, Hyeon Jong Moon, Su Hwan Kim, Bokyung Kim, Ji Won Kim, Kooklae Lee, Y. Seong, K.-W. Kim","doi":"10.7704/kjhugr.2024.0025","DOIUrl":"https://doi.org/10.7704/kjhugr.2024.0025","url":null,"abstract":"Esophageal perforation can lead to serious complications, and rapid diagnosis and treatment significantly affect the prognosis. Endoscopic vacuum-assisted closure (EndoVAC) therapy is widely accepted as a safe, well-tolerated, effective, versatile and practical procedure for the management of esophageal perforation in selected patients. We report the successful use of EndoVAC therapy for management of an esophageal perforation secondary to foreign body removal. A 56-year-old man presented to the emergency department for evaluation of chest pain after swallowing the plastic shell of a pill. Emergency endoscopy revealed an esophageal wall laceration (approximately 3 cm) and microperforation. The esophageal laceration and microperforation were limited to the mid-esophagus. The patient underwent EndoVAC therapy, which was repeated every 3–4 days for a total of six sessions over a period of 21 days. We observed improvement in the esophageal injury with granulation tissue formation during the fifth session. Subsequent follow-up evaluation, including esophagography and chest computed tomography confirmed complete healing of the esophageal injury. Following resumption of diet, the patienton a was discharged without any complications.","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":"112 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141362304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and Temporal Trend of Gastric Preneoplastic Lesions in Asia 亚洲胃癌前病变的发病率和时间趋势

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2024-06-10 DOI: 10.7704/kjhugr.2024.0024

Hee Seok Moon

引用次数: 0

Fungal Infection in Upper Gastrointestinal Tract 上消化道真菌感染

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2024-06-10 DOI: 10.7704/kjhugr.2024.0029

Ayoung Lee, Sung Woo Jung, Jung Mogg Kim

引用次数: 0

Rare Bacterial Infection of the Stomach 罕见的胃部细菌感染

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2024-06-10 DOI: 10.7704/kjhugr.2024.0015

Hyun Myung Cho, Su Jin Kim, Jin Ook Jang, Jung Wook Lee

引用次数: 0

Comparison of Tegoprazan- and Lansoprazole-Based Fourteen-Day Triple Therapies as First-Line Treatments for Helicobacter pylori Eradication 基于替戈普拉赞和兰索拉唑的十四天三联疗法作为根除幽门螺旋杆菌一线疗法的比较

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2024-06-10 DOI: 10.7704/kjhugr.2024.0012

Seok-Mo Kang, Nam-Hoon Kim, Seokhyeon Jeong, Jong Wook Kim, Jung Rock Moon, Yoon Suk Lee, Jun Hyuk Son

{"title":"Comparison of Tegoprazan- and Lansoprazole-Based Fourteen-Day Triple Therapies as First-Line Treatments for Helicobacter pylori Eradication","authors":"Seok-Mo Kang, Nam-Hoon Kim, Seokhyeon Jeong, Jong Wook Kim, Jung Rock Moon, Yoon Suk Lee, Jun Hyuk Son","doi":"10.7704/kjhugr.2024.0012","DOIUrl":"https://doi.org/10.7704/kjhugr.2024.0012","url":null,"abstract":"Objectives: Tegoprazan, a novel potassium-competitive acid blocker with rapid and effective antisecretory activity, was approved for the treatment of Helicobacter pylori infections in Korea in March 2020. However, real-world data regarding tegoprazan-based therapies are scarce. We compared the efficacies of tegoprazan- and lansoprazole-based triple therapies (TTs).Methods: Between March 2020 and February 2023, this study enrolled patients diagnosed with H. pylori infections who were prescribed either 14-day tegoprazan- or lansoprazole-based TTs as first-line treatments. Their medical records were retrospectively reviewed to compare H. pylori eradication rates and the rates of patient adherence to the recommended therapy.Results: A total of 670 patients diagnosed with H. pylori infections were prescribed 14-day TT regimens between March 2020 and February 2023 at Ilsan Paik Hospital (Goyang, Korea). Of those enrolled in the study, 64 received tegoprazan-based TT and 295 received lansoprazole-based TT as their first-line treatment. The H. pylori eradication rates for tegoprazan- and lansoprazole-based TTs were 76.6% and 75.6%, respectively, in the intent-to-treat population; the rates were 88.9% and 88.4%, respectively, in the per-protocol population (non-inferiority test, p=0.03 and p=0.01 in the respective populations). No significant differences were observed between the two groups with regards to treatment adherence rates (84.4% vs. 85.1%, p=0.78).Conclusions: As a first-line treatment for H. pylori eradication, 14-day tegoprazan-based TT demonstrated non-inferior efficacy compared with 14-day lansoprazole-based TT.","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":"117 17","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141361833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Characteristics and Outcomes in Patients With Localized Gastric Langerhans Cell Histiocytosis: A Case Series 局部胃朗格汉斯细胞组织细胞增生症患者的临床特征和预后：病例系列

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2024-06-10 DOI: 10.7704/kjhugr.2024.0019

Tae-Se Kim, Soomin Ahn, Y. Min, Hyuk Lee, J. Lee, P. Rhee, Jae J. Kim, B. Min

{"title":"Clinical Characteristics and Outcomes in Patients With Localized Gastric Langerhans Cell Histiocytosis: A Case Series","authors":"Tae-Se Kim, Soomin Ahn, Y. Min, Hyuk Lee, J. Lee, P. Rhee, Jae J. Kim, B. Min","doi":"10.7704/kjhugr.2024.0019","DOIUrl":"https://doi.org/10.7704/kjhugr.2024.0019","url":null,"abstract":"Objectives: Localized gastric Langerhans cell histiocytosis (LCH) characterized by abnormal proliferation of Langerhans cells in the stomach without systemic involvement, is rare; therefore, the clinical characteristics and outcomes of LCH remain unclear. We investigated the clinical characteristics and outcomes in patients diagnosed with localized gastric LCH and have also discussed treatment strategies for this rare disease.Methods: The study included seven patients diagnosed with localized gastric LCH at our hospital between September 1997 and December 2023. We retrospectively reviewed medical records and analyzed the clinicopathological characteristics and patient outcomes.Results: Endoscopically, localized gastric LCH appeared as a small erosion in the distal part of the stomach. Positron emission tomography-computed tomography revealed normal findings in 100.0% (4/4) of patients during pre-treatment workup. Immunohistochemical analysis using S-100 and CD1a showed immunopositive cells in all tested patients. Of the six patients who underwent follow-up, two (33.3%) showed metachronous recurrence at a location distinct from the initial site. However, all patients eventually showed spontaneous regression of the disease, and no gastric LCH-induced mortality was observed during follow-up.Conclusions: Careful and regular surveillance may be sufficient for patients with localized gastric LCH without systemic involvement.","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":" 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141363877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parasitic Diseases of Upper Gastrointestinal Tract 上消化道寄生虫病

The Korean Journal of Helicobacter and Upper Gastrointestinal Research Pub Date : 2024-06-10 DOI: 10.7704/kjhugr.2024.0026

Heung Up Kim

{"title":"Parasitic Diseases of Upper Gastrointestinal Tract","authors":"Heung Up Kim","doi":"10.7704/kjhugr.2024.0026","DOIUrl":"https://doi.org/10.7704/kjhugr.2024.0026","url":null,"abstract":"Korea was a hotspot for parasitic infections until modern times. However, following economic development, improved health and hygiene and farming methods, and successful implementation of active deworming programs, human parasites are rare. Currently, medical and scientific advances have improved the survival rate of elderly and immunocompromised hosts, and immunosuppressants are widely administered for treatment, which may predispose patients to parasitic and various opportunistic infections. Furthermore, globalization has led to the entry of an increasing number of individuals from various countries into Korea, which increases the risk of transmission of parasites from foreign countries into Korea. However, parasitic diseases will tend to disappear in Korea, which may lead to reduced proficiency and diagnostic rate of existing stool tests, and new diagnostic methods tailored to Korea are unavailable. Currently, endoscopy is widely used as a standard method for gastrointestinal disease evaluation in Korea, and endoscopically detected parasites or parasite-induced abnormalities are useful to establish diagnosis in many cases. In this article, the author summarize the current status of endoscopic detection of parasitic diseases affecting the upper gastrointestinal tract.","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":"101 32","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141361417","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0