The Indonesian Journal of Infectious Diseases最新文献_第9页

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The Indonesian Journal of Infectious Diseases Pub Date : 2022-02-26 DOI: 10.1093/infdis/jiac071

J. Cyktor, R. Bosch, H. Mar, B. Macatangay, Annina Collier, E. Hogg, C. Godfrey, J. Eron, D. McMahon, J. Mellors, R. Gandhi

引用次数: 0

Neutralizing Activities against the Omicron Variant after a Heterologous Booster in Healthy Adults Receiving Two Doses of CoronaVac Vaccination 在接受两剂冠状病毒疫苗接种的健康成人中，异源加强剂对组粒变异的中和活性

The Indonesian Journal of Infectious Diseases Pub Date : 2022-01-29 DOI: 10.1101/2022.01.28.22269986

S. Assawakosri, S. Kanokudom, N. Suntronwong, C. Auphimai, P. Nilyanimit, P. Vichaiwattana, T. Thongmee, T. Duangchinda, W. Chantima, P. Pakchotanon, D. Srimuan, T. Thatsanatorn, S. Klinfueng, R. Yorsaeng, N. Sudhinaraset, Nasamon Wanlapakorn, J. Mongkolsapaya, S. Honsawek, Y. Poovorawan

{"title":"Neutralizing Activities against the Omicron Variant after a Heterologous Booster in Healthy Adults Receiving Two Doses of CoronaVac Vaccination","authors":"S. Assawakosri, S. Kanokudom, N. Suntronwong, C. Auphimai, P. Nilyanimit, P. Vichaiwattana, T. Thongmee, T. Duangchinda, W. Chantima, P. Pakchotanon, D. Srimuan, T. Thatsanatorn, S. Klinfueng, R. Yorsaeng, N. Sudhinaraset, Nasamon Wanlapakorn, J. Mongkolsapaya, S. Honsawek, Y. Poovorawan","doi":"10.1101/2022.01.28.22269986","DOIUrl":"https://doi.org/10.1101/2022.01.28.22269986","url":null,"abstract":"Background. The use of an inactivated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine (CoronaVac) against SARS-CoV-2 is implemented worldwide. However, waning immunity and breakthrough infections have been observed. Therefore, we hypothesized that the heterologous booster might improve the protection against the delta and omicron variants. Methods. A total of 224 individuals who completed the two-dose CoronaVac for six months were included. We studied reactogenicity and immunogenicity following a heterologous booster with the inactivated vaccine (BBIBP), the viral vector vaccine (AZD1222), and the mRNA vaccine (both BNT162B2 and mRNA-1273). We also determined immunogenicity at 3- and 6-months boosting intervals. Results. The solicited adverse events (AEs) were mild to moderate and well-tolerated. Total RBD immunoglobulin (Ig), anti-RBD IgG, focus reduction neutralization test (FRNT50) against delta and omicron variants, and T cell response were highest in the mRNA-1273 group followed by the BNT162b2, AZD1222 and BBIBP groups, respectively. We also witnessed a higher total Ig anti-RBD in the long-interval than in the short-interval groups. Conclusions. All four booster vaccines significantly increased binding and NAbs in individuals immunized with two doses of CoronaVac. The present evidence may benefit vaccine strategies development to thwart variants of concern, including the omicron variant. Keywords. COVID-19; Third dose; heterologous booster; omicron; mRNA-1273; BNT162b2; AZD1222; NAbs; T cells.","PeriodicalId":22572,"journal":{"name":"The Indonesian Journal of Infectious Diseases","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87124613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 48

Screening for SARS-CoV-2 in close contacts of individuals with confirmed infection: performance and operational considerations 在确诊感染者密切接触者中筛查SARS-CoV-2:性能和操作考虑因素

The Indonesian Journal of Infectious Diseases Pub Date : 2022-01-28 DOI: 10.1101/2022.01.27.22269904

S. Zobrist, M. Oliveira-Silva, Alexia Martines Vieira, P. Bansil, E. Gerth-Guyette, B. Leader, A. Golden, Hannah C. Slater, Catherine Duran de Lucena Cruz, E. Garbin, Mariana Sagalovsky, S. Pal, Vin Gupta, L. Wolansky, Deusilene Souza Vieira Dall'Acqua, G. Naveca, Valdinete Alves do Nascimento, Juan Miguel Villalobos Salcedo, P. Drain, Alexandre Dias Tavares Costa, G. Domingo, D. Pereira

{"title":"Screening for SARS-CoV-2 in close contacts of individuals with confirmed infection: performance and operational considerations","authors":"S. Zobrist, M. Oliveira-Silva, Alexia Martines Vieira, P. Bansil, E. Gerth-Guyette, B. Leader, A. Golden, Hannah C. Slater, Catherine Duran de Lucena Cruz, E. Garbin, Mariana Sagalovsky, S. Pal, Vin Gupta, L. Wolansky, Deusilene Souza Vieira Dall'Acqua, G. Naveca, Valdinete Alves do Nascimento, Juan Miguel Villalobos Salcedo, P. Drain, Alexandre Dias Tavares Costa, G. Domingo, D. Pereira","doi":"10.1101/2022.01.27.22269904","DOIUrl":"https://doi.org/10.1101/2022.01.27.22269904","url":null,"abstract":"Background. Point-of-care and decentralized testing for SARS-CoV-2 is critical to inform public health responses. Performance evaluations in priority use cases such as contact tracing can highlight trade-offs in test selection and testing strategies. Methods. A prospective diagnostic accuracy study was conducted among close contacts of COVID-19 cases in Brazil. Two anterior nares swabs (ANS), a nasopharyngeal swab (NPS), and saliva were collected at all visits. Vaccination history and symptoms were assessed. Household contacts were followed longitudinally. Three rapid antigen tests and one molecular method were evaluated for usability and performance against reference RT-PCR on NPS. Results. Fifty index cases and 214 contacts (64 household) were enrolled. Sixty-five contacts were RT-PCR positive during at least one visit. Vaccination did not influence viral load. Gamma variants were most prevalent; Delta emerged increasingly during implementation. Overall sensitivity of evaluated tests ranged from 33% to 76%. Performance was higher among symptomatic cases and cases with Ct<34 and lower among oligo/asymptomatic cases. Assuming a 24-hour time-to-result for RT-PCR, the cumulative sensitivity of an ANS rapid antigen test was >70% and almost 90% after four days. Conclusions. The near immediate time-to-result for antigen tests significantly offsets lower analytical sensitivity in settings where RT-PCR results are delayed or unavailable.","PeriodicalId":22572,"journal":{"name":"The Indonesian Journal of Infectious Diseases","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87051519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

OUP accepted manuscript OUP接受稿件

The Indonesian Journal of Infectious Diseases Pub Date : 2022-01-01 DOI: 10.1093/infdis/jiac160

引用次数: 0

OUP accepted manuscript OUP接受稿件

The Indonesian Journal of Infectious Diseases Pub Date : 2022-01-01 DOI: 10.1093/infdis/jiac159

引用次数: 0

OUP accepted manuscript OUP接受稿件

The Indonesian Journal of Infectious Diseases Pub Date : 2022-01-01 DOI: 10.1093/infdis/jiac111

引用次数: 0

Physical Measurement Analysis in Pre-Utility Covid-19 Isolation Room: A Case Study Universitas Mataram Teaching Hospital 应用前新冠肺炎隔离室物理测量分析——以马塔兰大学教学医院为例

The Indonesian Journal of Infectious Diseases Pub Date : 2021-11-26 DOI: 10.32667/ijid.v7i2.121

E. H. Wardoyo, I. B. Alit, Monalisa Nasrul, D. Yudhanto, Prima Belia Fathana, R. S. Saptaningtyas

引用次数: 0

Surveilans Epidemiologi Kasus Terkonfirmasi COVID-19 pada Pasien Rawat Inap di Rumah Sakit Pusat Infeksi Prof. Dr. Sulianti Saroso Tahun 2020 2020年，Sulianti Saroso博士感染中心住院病人的病因流行病学检验证实

The Indonesian Journal of Infectious Diseases Pub Date : 2021-11-26 DOI: 10.32667/ijid.v7i2.127

H. Herlina, Anita Puspitasari Diah Nugroho, Siti Maemun, Intansari Pertiwi, Farida Murtiani, Andi Dala Intan Sapta Nanda

{"title":"Surveilans Epidemiologi Kasus Terkonfirmasi COVID-19 pada Pasien Rawat Inap di Rumah Sakit Pusat Infeksi Prof. Dr. Sulianti Saroso Tahun 2020","authors":"H. Herlina, Anita Puspitasari Diah Nugroho, Siti Maemun, Intansari Pertiwi, Farida Murtiani, Andi Dala Intan Sapta Nanda","doi":"10.32667/ijid.v7i2.127","DOIUrl":"https://doi.org/10.32667/ijid.v7i2.127","url":null,"abstract":"Latar Belakang: Surveilans epidemiologi adalah pengamatan terus menerus terhadap perkembangan kasus dan kematian melalui analisis dan intervensi epidemiologi yang terstandar dengan tujuan untuk membatasi penyebaran penyakit, sebagai bahan bagi pemerintah daerah, otoritas Kesehatan masyarakat dan rumah sakit untuk mengelola kasus penyakit (dalam hal ini COVID-19), surveilans juga dibutuhkan untuk memantau tren jangka panjang penularan COVID-19 dan perubahan virus. Metode: surveilans pasif dan aktif Surveilans pasif adalah surveilans dengan cara mengambil data dari sumber status pasien (rekam medik) dan laporan dari ruang perawatan, sementara surveilans aktif adalah mencari data langsung ke pasien (menanyakan langsung kepada pasien dengan cara menelpon ataupun melalui whatsapp ). Hasil: Jumlah pasien rawat inap COVID-19 tahun 2021 sebanyak 1065 pasien, sebagian besar kasus antara lain laki-laki (573 pasien), kelompok umur >18 tahun (1028 pasien), domisili Jakarta Utara (288 pasien), datang sendiri (35%)., sebagian besar pasien keluar hidup (911 pasien) dan hasil PCR terkonfirmasi (880 pasien). Kesimpulan: Pelaksanaan surveilans epidemiologi kasus COVID-19 di RSPI Sulianti Saroso berdasarkan orang , tempat dan waktu ( variable jumlah kasus, umur, jenis kelamin, asal domisili, pemeriksaan , luaran pasien dan asal rujukan). Surveilans sangat dibutuhkan untuk evaluasi pelayanan dan program penanggulangan penyakit, oleh karena itu dibutuhkan dukungan kelengkapan data dan ketepatan waktu pelaporan untuk mendapatkan data yang valid.","PeriodicalId":22572,"journal":{"name":"The Indonesian Journal of Infectious Diseases","volume":"10 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87037723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pengaruh Pemberian Posisi Lateral Terhadap Saturasi Oksigen dan Frekuensi Pernapasan pada Anak dengan Gangguan Pemenuhan Kebutuhan Oksigenasi di Ruang Rawat Infeksi Anak 侧向位置对儿童的氧饱和度和呼吸频率的影响，儿童感染病房缺乏氧气需求

The Indonesian Journal of Infectious Diseases Pub Date : 2021-11-26 DOI: 10.32667/ijid.v7i2.122

Paskaliana Hilpriska Danal, Nani Nurhaeni, Dessie Wanda

{"title":"Pengaruh Pemberian Posisi Lateral Terhadap Saturasi Oksigen dan Frekuensi Pernapasan pada Anak dengan Gangguan Pemenuhan Kebutuhan Oksigenasi di Ruang Rawat Infeksi Anak","authors":"Paskaliana Hilpriska Danal, Nani Nurhaeni, Dessie Wanda","doi":"10.32667/ijid.v7i2.122","DOIUrl":"https://doi.org/10.32667/ijid.v7i2.122","url":null,"abstract":"Latar Belakang: Masalah pemenuhan kebutuhan oksigenasi pada anak sering disebabkan oleh ketidakpatenan jalan napas sehingga modifikasi posisi tubuh salah satunya posisi lateral untuk meningkatkan kelancaran oksigenasi pada anak merupakan intervensi yang efektif. Study ini bertujuan untuk mengidentifikasi pengaruh pemberian posisi lateral terhadap perubahan saturasi oksigen dan frekuensi pernapasan pada anak dengan gangguan pemenuhan kebutuhan oksigenasi di ruang rawat infeksi anak. Metode: Desain kuasi eksperimen. Responden dalam study ini berjumlah 36 orang yang dibagi ke dalam kelompok pemberian posisi lateral dan kelompok yang diberikan posisi sesuai standar perawatan rumah sakit sebagai kontrol, masing-masing 18 responden. Pengumpulan data dilakukan dengan mengukur saturasi oksigen dan frekuensi pernapasan sebelum dan sesudah diberikan intervensi. Analisis data menggunakan uji paired t-test dan Wilcoxon untuk menilai adanya perbedaan saturasi oksigen dan frekuensi pernapasan anak sebelum dan sesudah intervensi. Uji independent t-test dan Mann Whitney digunakan untuk menganalisis perbedaan saturasi oksigen dan frekuensi pernapasan antar kelompok. Hasil: analisis statistik menunjukkan terdapat perbedaan signifikan antara saturasi oksigen (p value < 0,05) dan frekuensi pernapasan (p value < 0,05) sebelum dan sesudah diberikan posisi lateral. Kesimpulan: posisi lateral dapat dijadikan salah satu intervensi keperawatan mandiri yang dapat diterapkan dalam memberikan asuhan pada anak dengan masalah pemenuhan kebutuhan oksigenasi di ruang rawat.","PeriodicalId":22572,"journal":{"name":"The Indonesian Journal of Infectious Diseases","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81554104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gambaran Pegawai Terkonfirmasi COVID-19 di Rumah Sakit Pusat Infeksi Sulianti Saroso Tahun 2020

The Indonesian Journal of Infectious Diseases Pub Date : 2021-11-26 DOI: 10.32667/ijid.v7i2.126

Anita Puspitasari Dyah Nugroho, Herlina Herlina, Nunung Hendrawati, Siti Maemun, I. Pertiwi, Farida Murtiani, Andi Dala Intan Sapta Nanda

{"title":"Gambaran Pegawai Terkonfirmasi COVID-19 di Rumah Sakit Pusat Infeksi Sulianti Saroso Tahun 2020","authors":"Anita Puspitasari Dyah Nugroho, Herlina Herlina, Nunung Hendrawati, Siti Maemun, I. Pertiwi, Farida Murtiani, Andi Dala Intan Sapta Nanda","doi":"10.32667/ijid.v7i2.126","DOIUrl":"https://doi.org/10.32667/ijid.v7i2.126","url":null,"abstract":"Latar Belakang: Tenaga kesehatan yang berada di garis depan penanganan COVID-19 berisiko tinggi terinfeksi COVID-19 sehingga hasil surveilans menjadi dasar strategi untuk melindungi tenaga kesehatan, menghambat penyebaran infeksi dan mengurangi risiko transmisi. Tujuan: Mengetahui gambaran pegawai yang terkonfirmasi COVID-19 di RSPI Sulianti Saroso tahun 2020 berdasakan data surveilans. Metode: Desain deskriptif cross-sectional, total sampel 173 sampel, data sekunder bersumber dari data hasil RT-PCR dan data surveilans epidemiologi. Hasil: Kejadian infeksi COVID-19 dimulai pada bulan Maret 2020, puncak kasus pegawai tertinggi minggu ke-35, terbesar pada pegawai perempuan (60%), rentang umur 29-38 tahun (38%), terbesar pada tenaga kesehatan perawat (38%). Pegawai yang mengalami tanda & gejala (58%), melaksanakan isolasi mandiri (63%) dan sembuh (98%). Kesimpulan: Gambaran pegawai yang terkonfirmasi COVID-19 di RSPI Sulianti Saroso tahun 2020 dilihat berdasarkan jenis kelamin, umur, jenis ketenagaan, tanda dan gejala, tindak lanjut penanganan dan luaran","PeriodicalId":22572,"journal":{"name":"The Indonesian Journal of Infectious Diseases","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82254390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0