Tanaffos最新文献

{"title":"From Cystic Lung Lesions to Pulmonary Lymphangioleiomyomatosis: A Case-Based Diagnostic and Therapeutic Approach.","authors":"Mohsen Sadeghi, Fatemeh Sadat Hosseini Khajouei, Amir Morteza Soleimani","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Lymphangioleiomyomatosis (LAM) is a rare, progressive cystic lung disease that primarily affects women of reproductive age. It arises from abnormal proliferation of smooth muscle-like cells, resulting in cystic lung remodeling, impaired airflow, and recurrent pneumothorax. Serum vascular endothelial growth factor D (VEGF-D) can support diagnosis, but normal levels do not exclude the disease.</p><p><strong>Case presentation: </strong>We describe a 37-year-old woman with six months of progressive dyspnea and hypoxia (SaO₂: 86%). High-resolution CT revealed diffuse, thin-walled cystic lesions. VEGF-D levels were within the normal range. Pulmonary function tests showed moderate obstructive impairment (FEV₁ 61%, FEV₁/FVC: 64%) and reduced diffusing capacity (DLCO: 45%). Transbronchial lung biopsy confirmed LAM with HMB-45 positivity. Sirolimus therapy was initiated in response to symptomatic impairment.</p><p><strong>Conclusion: </strong>This case shows that normal VEGF-D levels do not rule out LAM. Histopathologic confirmation remains essential when clinical and imaging findings are suggestive. Timely diagnosis enables initiation of mTOR inhibitor therapy, which can help stabilize lung function, manage cystic lesions, and inform decisions about further interventions, including lung transplantation.</p>","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"24 3","pages":"303-308"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13585209/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Could Remdesivir be used in the Presence of Elevated Liver Enzymes Secondary to COVID-19 Infection in Children? A Case Report.","authors":"Shirin Sayyahfar, Sanaz Khajouii, Elham Zarei, Motahareh Tahami","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Abnormal liver biochemistry values are not unusual in patients with COVID-19 infection. Remdesivir is one of the drugs that is currently used for the treatment of COVID-19 infection, but one of the side effects of this drug is hepatotoxicity. According to the local guidelines of the Iranian Ministry of Health, remdesivir should be monitored serially before, during, and at the end of treatment, and withheld if liver function tests (LFTs) rise more than 5 times the upper limit of normal. Herein, we report a pediatric case of severe acute respiratory syndrome (SARS) coronavirus (CoV)-2(SARS-CoV-2) pneumonia and elevated liver enzymes who was treated with remdesivir despite the first LFTs of more than five times the upper limit of normal. The LFTs improved during treatment and reached near-normal values at the time of hospital discharge. Indications of remdesivir usage in the setting of elevated liver enzymes due to SARS-CoV-2 infection remain to be defined.</p>","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"24 3","pages":"299-302"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13585210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lived Experiences of the Health Care Providers Infected with Coronavirus Disease: A Phenomenological Study.","authors":"Elham Ghazanchaei, Mohammad Varahram, Fatemeh Keyvani Rad, Beheshteh Jebelli","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>With the COVID-19 outbreak and the involvement of many countries, Healthcare Providers (HCPs), as a large group on the front lines of handling this disease, have been exposed to the virus the most and faced heavy pressure with limited resources and facilities, resulting in many of these individuals becoming infected. Accordingly, the current research was conducted to investigate and identify the lived experiences of HCPs during the COVID-19 pandemic at Masih Daneshvari Hospital in Tehran, the first hospital to admit patients with COVID-19.</p><p><strong>Materials and methods: </strong>This study employs a qualitative approach with a conventional content analysis method, where data collection and analysis were conducted according to the steps outlined by Graneheim and Lundman. The study population in this research consisted of 42 people, including 26 females and 16 males, selected from the HCPs working in Masih Daneshvari Hospital wards. The interviews were conducted semi-structured and face-to-face until saturation was reached.</p><p><strong>Results: </strong>One thousand and nineteen initial codes were extracted through the collection and analysis of participants' data. After reviewing and equalizing similar codes, 62 final codes were extracted. Also, 6 main categories and 14 subcategories were extracted from interviews with the HPCs infected with COVID-19: Physical and mental challenges (psychological effects, job burnout, disease symptoms), cultural-belief challenges (beliefs and values, and moral conflicts), social challenges (occupational conflicts, social stigma), family challenges (economic-livelihood problems, work-family conflict), challenges related to the disease characteristics (informed management, disease unknown and difficult conditions), and the challenge of facilities, equipment, and human resources (hospital capacities, popular volunteer forces, organizational changes, and support) were extracted.</p><p><strong>Conclusion: </strong>The results of this study indicated that the HPCs faced challenges regarding emotions, interpersonal relationships with colleagues and relatives, the workplace, and the difficulty of the workplace when infected with COVID-19. In this regard, it is essential to use strategies such as benefitting from sufficient preparation before the outbreak concerning equipment, human force, required training about the disease and its process, making the HPCs skillful, and creating numerous incentives.</p>","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"24 3","pages":"281-291"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13585212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Definition of Asthma in the Middle Ages.","authors":"Reza Mohammadinasab, Javad Ghazi Sha'rbaf, Ali Taghizadieh, Marianna Karamanou, Saeid Safiri, Spyros N Michaleas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the Middle Ages, asthma had a legacy from antiquity. The most accurate one was Galen (129-216 AD). In the Middle Ages, Ali ibn Rabban Tabari (838-870 AD) first introduced asthma and explained its different types. After him, many physicians devoted a significant part of their work to this disease. We searched the original versions of historical books and used a narrative approach to report the history of asthma. Pneumonia, inflammation of the spleen, and softness and stiffness of the chest muscles are some of the factors that have been suggested as the causes of asthma. However, the most accurate cause was given by Ibn Sina (980-1037), and he gave many detailed reasons for it. In addition to the previous reasons, which he listed according to a much more accurate classification than his predecessors, he cited other problems such as the presence of sputum, dry lungs, dry cough, sputum caused by neurological diseases, diseases of the organs adjacent to the respiratory organs, and congenital injuries as causes. Of course, other factors have been added by other physicians, the most notable of which are hereditary problems and diseases such as nosebleeds and pneumonia. The accurate observations of physicians in the Middle Ages provide a detailed and comprehensive description of asthma. The definitions and classification of different types of asthma were an important element in designing the treatment plan.</p>","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"24 3","pages":"206-212"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13585147/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Network Analysis of Severe Asthma in Female Patients to Find Possible Drug Targets.","authors":"Hamideh Moravvej, Zahra Razzaghi, Mitra Rezaei, Babak Arjmand, Nastaran Asri, Mostafa Rezaei Tavirani","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Severe asthma (SA) has been a challenging health issue worldwide. In this view, a complementary study of gene expression profiles could be helpful. Protein-protein interaction network analysis could help better understand the molecular changes and, ultimately, the underlying mechanisms of treatment approaches. The identification of the critical genes involved in severe asthma is the main aim of this study.</p><p><strong>Materials and methods: </strong>Data were retrieved from the Gene Expression Omnibus (GEO) database and pre-evaluated via GEO2R to find the significantly differentially expressed genes (DEGs). Cytoscape software and its plugin were used to facilitate protein-protein interaction (PPI) network analysis and gene ontology enrichment.</p><p><strong>Results: </strong>A total of 30 significant DEGs were identified as the genes that differentiate severe asthma from control samples. PPI network analysis led to the identification of four hub-bottlenecks, including TP53, AKT1, ACTB, and EGFR, and two hubs (GAPDH and PTEN). DLG4 was highlighted as a bottleneck node. \"Nitric-oxide synthase\", \"lymphocyte apoptotic process\", \"regulation of cyclin-dependent protein serine/threonine kinase activity\", and \"positive regulation of miRNA maturation\" biological processes were linked to the central genes.</p><p><strong>Conclusion: </strong>AKT1 and EGFR, and the related biological processes, can be considered as the possible drug targets for severe asthma.</p>","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"24 3","pages":"223-228"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13585151/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing the Knowledge about HIV and HPV Infections among the General Population of Iran.","authors":"Reza M Robati, Amir-Reza Derakhshan, Atousa Yazdanshenas, Nikoo Mozafari, Mitra Rezaei, Vahid Mansouri","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Governmental sexually transmitted disease (STD) educational programs are more focused on HIV/AIDS, and knowledge about other STDs, such as HPV, is low. To test this hypothesis and allow government authorities to modify the sexual health education policies and programs, we developed a survey to assess and compare the current level and sources of HPV and HIV information in the general population.</p><p><strong>Materials and methods: </strong>In this cross-sectional study, an online questionnaire containing 46 items was created and distributed using a web-based application. Respondents were asked to provide information about their knowledge of HIV/AIDs, HPV infection, and HPV vaccination.</p><p><strong>Results: </strong>A total of 370 (36.56%) males and 642 (63.44%) females participated in this study. Regarding overall knowledge of HPV and HIV/AIDS, the awareness scores of HIV/AIDS were significantly higher compared to HPV scores (71.39±23.66 vs 35.90 ± 23.65, P<.001). Only 2.8% of participants had not heard about HIV, while 26.5% and 75.0% had never heard about HPV and HPV vaccination, respectively. Only 11.2% of participants were aware of the protective role of vaccination against cervical cancer. The most frequent source for HIV information was national radio and television, which do not have a substantial role in HPV.</p><p><strong>Conclusion: </strong>Although HPV and HIV are both infections that can be transmitted sexually, the overall knowledge of the general public about HPV is substantially lacking compared to HIV. The findings of this study highlight the real need for the implementation of health education programs on STDs, particularly regarding HPV and HPV vaccination.</p>","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"24 3","pages":"245-251"},"PeriodicalIF":0.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13585152/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Performance and Learning Curve of EBUS-Guided TBNA in Western India: A Retrospective Analysis.","authors":"Ram Niwas Jalandra, Aneesa Shahul S, Poonam Elhence, Naveen Dutt, Nishant Kumar Chauhan, Shahir Asfahan, Kunal Deokar","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has emerged as a minimally invasive and highly effective modality for evaluating mediastinal and hilar lymphadenopathy. This study aimed to assess the diagnostic performance and analyze the learning curve of EBUS-guided TBNA during the first two years of its implementation at a tertiary care center in Western India.</p><p><strong>Materials and methods: </strong>Retrospective data of EBUS bronchoscopy procedures and their outcomes were collected from the bronchoscopy suite of a tertiary care hospital in Western India. Data were collected using a Google form for the first two years of EBUS operation. The percentage of diagnostic procedures conducted during each quarter was calculated over the two years. The difference in the distribution of determinate to indeterminate procedures between the first and the second year was assessed using the Chi-Square test. Statistical and graphical analyses were performed using Python 3.6.</p><p><strong>Results: </strong>Based on the cytology reports, out of 144 EBUS procedures conducted, 90 (62.5%) resulted in a diagnosis. Station 7 mediastinal node was the most frequently sampled. Among the determinate procedures, squamous cell carcinoma (31.1%) was the most frequently diagnosed. The average yield for the first four quarters was 57.4%, and for the next four quarters, it was 64.9%. There was a 7.5% increase in yield in the second year of EBUS operation; however, the difference was non-significant (p=0.46).</p><p><strong>Conclusion: </strong>In the first two years after acquiring EBUS equipment, EBUS-guided TBNA had a diagnostic yield of 62.5% in an academic institute. The diagnostic yield increased during the second year, likely due to a combination of improved operator skills and wise patient selection.</p>","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"24 2","pages":"150-155"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13102339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147781130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Smoking Rates and Disease Severity in COVID-19 Patients at Masih Deneshvari Hospital.","authors":"Zahra Hessami, Maryam Vasheghani, Hooman Sharifi, Mahshid Aryanpur, Hakimeh Sheikhzadeh","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Considering that smoking is a major risk factor for respiratory diseases and viral infections, in this study, we investigated the smoking status in patients admitted with the diagnosis of COVID-19 at Masih Daneshvari Hospital.</p><p><strong>Materials and methods: </strong>The information was obtained through the registration of patients' information in the hospital.</p><p><strong>Results: </strong>A total of 776 patients with COVID-19 who were admitted to Masih Daneshvari Hospital from April 2019 to June 2020 were examined, among whom 422 were men (54.4%), and 352 were women (45.5%). The mean age of the studied patients was 55.7 with a standard deviation of 15.9. The mean duration of hospitalization was 10.3 days with a standard deviation of 6.7 days. 178 (23.4%) patients were smokers. 45 smokers (25.3%) were hospitalized for more than 3 weeks, while 35 (6%) non-smokers were hospitalized for more than 3 weeks (p<0.05). There was no significant difference between smokers and non-smokers in terms of hospitalization in the intensive care unit and mortality.</p><p><strong>Conclusion: </strong>The significant finding is the high prevalence of smoking in the patient population, which should be taken into consideration. The higher length of hospitalization in smokers is also a notable finding that can cause problems for the health system and patients. Encouragement to quit smoking should be considered in health programs.</p>","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"24 2","pages":"194-197"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13102336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147781786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traditional and Short Course Treatment for Multidrug-Resistant Tuberculosis: A Comparative Study in National Referral Centers.","authors":"Parvaneh Baghaei, Jonathon R Campbell, Amirmohsen Mahdavian, Zahra Abtahian, Majid Marjani, Afshin Moniri, Mohammad Varahram, Mehdi Kazempour, Payam Tabarsi","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Treatment of multidrug-resistant tuberculosis (MDR-TB) is difficult, expensive, and requires prolonged periods of time. Recent studies recommended short-course therapy (shorter regimen) for 9 months to one year. This study aimed to evaluate the response of the short-course therapy compared with traditional treatment in MDR-TB patients.</p><p><strong>Materials and methods: </strong>From all 94 referred MDR-TB cases, 48 patients were included in this study. Shorter regimen consisted of Moxifloxacin, Prothionamide, Amikacin, Clofazimine, Linezolid, Ethambutol, Pyrazinamide, and Cycloserine, and longer regimens consisted of the mentioned drugs, except Clofazimine and Linezolid, were prescribed randomly: in equal (24 in each group). The patients were monitored and evaluated for any complications and were followed for five years for relapse.</p><p><strong>Results: </strong>The median age was 39 years. The median interval for smear conversion was 30 days (20- 58 days) and was shorter in the short-course group (36 vs. 49 days). Also, the mean interval of sputum culture conversion in the shorter group and standard was 32 and 56 days, respectively, which is not related to the outcome of treatment. Eight of twelve patients who developed severe adverse effects were in shorter regimen. There was no difference between the two groups for the outcome of TB treatment. There is no relation between the outcome and other factors. None of them relapsed after three years following the end of the treatment.</p><p><strong>Conclusion: </strong>Shorter treatment can increase the cure rate and cooperation and adherence of the patients. It would be better to consider a shorter regimen in the national TB program for strengthening favorable treatment.</p>","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"24 2","pages":"114-127"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13102292/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147781815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mini-Nutritional Assessment Test and Fat-Free-Mass Depletion in Tunisian Chronic Obstructive Pulmonary Disease Patients.","authors":"Soumaya Khaldi, Khouloud Kchaou, Asma Chaker, Rim Kammoun, Sahar Chakroun, Faten Chaieb, Masmoudi Kaouthar, Saloua Ben Khamsa","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Background: </strong>Fat-Free Mass (FFM) depletion is one of the systemic manifestations of COPD, causing functional impairment. We aimed to evaluate the relevance of the Mini-Nutritional Assessment (MNA) test in predicting FFM depletion in Tunisian COPD patients and to determine the relationship between nutritional status and disease severity.</p><p><strong>Materials and methods: </strong>This was a cross-sectional study of patients with stable COPD. Respiratory function was assessed. The MNA test and the COPD Assessment Test (CAT) questionnaire were also completed. FFM was measured by bioelectrical impedance analysis. Fat-Free Mass Index (FFMI) was calculated according to the following formula: FFM (kg)/height (m)². FFM depletion was defined as a FFMI < 16 kg/m².</p><p><strong>Results: </strong>The study population consisted of 160 patients with COPD. FFM depletion was higher in patients with more severe COPD. Patients with FFM depletion had a lower MNA score than patients without FFM depletion. The independent predictors of FFM depletion in COPD were MNA (p<0.0001; OR=0.333; CI: 0.2-0.552) and BMI (p<0.0001; OR=0.547; CI: 0.408-0.733). The MNA score was significantly correlated with FFMI, CAT score, and lung function. ROC curve analysis defined a value of 19.25 as the optimal cut-off value of the MNA score to discriminate COPD patients with FFM depletion from those without FFM depletion. By using this value, the sensitivity and specificity of the MNA test for detecting FFM depletion were 90% and 74%, respectively.</p><p><strong>Conclusion: </strong>Our results suggest that the MNA test, a simple and universally available tool, can predict FFM depletion in COPD.</p>","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"24 2","pages":"156-162"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13102335/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147781754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}