Tanaffos Pub Date : 2024-04-01

Ladan Kharraz, Aida Bagheri, Firouze Hatami, Mohammad Mahdi Rabiei, Farid Javandoust Gharehbagh, Ilad Alavi Darazam

{"title":"Assessment of Clinical, Histopathologic, and Radiologic Features in Extrapulmonary Tuberculosis Patients.","authors":"Ladan Kharraz, Aida Bagheri, Firouze Hatami, Mohammad Mahdi Rabiei, Farid Javandoust Gharehbagh, Ilad Alavi Darazam","doi":"","DOIUrl":"","url":null,"abstract":"Background: Tuberculosis (TB) is clinically divided into two categories: pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB). PTB has many different manifestations, and sometimes the initial diagnosis is challenging and depends on the prevalence of infection as well as the experience and development of local medical centers. Thus, we aimed to review all EPTB patients in our referral center.Materials and methods: This retrospective study reviewed all confirmed cases of EPTB referred to a referral/general center within the last decade.Results: This study included 68 cases of EPTB. Percentages of males and females were 58.8% and 41.2%, respectively. The majority of EPTB patients were TB meningitis (44.1%), followed by musculoskeletal TB (17.6%). About 8.8% of patients had a positive culture. The acid-fast bacilli test was found to be positive in 19.1% of cases. The mortality rate in this study was 19.1% and the highest rate of mortality was observed in intestinal and mesenteric TB (33.3%).Conclusion: According to this study, the majority of hospitalized EPTB patients had TB meningitis. The mortality rate in intestinal and mesenteric TB was higher compared to other types of EPTB, probably due to delayed diagnosis. In the current study, Positive results for smears and cultures were also low.","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"23 4","pages":"349-354"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464834/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Symptoms and Echocardiographic Markers Regarding the Severity of Embolism in Patients with Acute Pulmonary Embolism. 急性肺栓塞患者栓塞严重程度的临床症状和超声心动图指标

Tanaffos Pub Date : 2024-04-01

Shahabaddin Sorouri, Maryam Naseri, Sepideh Hejazi

{"title":"Clinical Symptoms and Echocardiographic Markers Regarding the Severity of Embolism in Patients with Acute Pulmonary Embolism.","authors":"Shahabaddin Sorouri, Maryam Naseri, Sepideh Hejazi","doi":"","DOIUrl":"","url":null,"abstract":"Background: Echocardiography can be used for risk stratification in patients with acute pulmonary embolism (PE). While the severity of PE has been assessed through laboratory criteria in most studies, the Pulmonary Embolism Severity Index (PESI) scoring system was used in this study to evaluate the severity of echocardiographic criteria in acute PE patients.Materials and methods: All PE patients admitted to Ghaem Hospital in Mashhad between 2021-2022 were included in the study. Clinical symptoms and echocardiographic markers were checked and recorded when the patients entered the study. Data were analyzed in SPSS version 24 at a significance level of 0.05 using the Chi-square test and t-test.Results: Of 40 patients, 80% were at a high risk of PESI. The most common clinical symptoms were dyspnea (97.5%) and pleuritic chest pain (75%). Right ventricle (RV) size enlargement and its dysfunction were recorded in 57.5% of patients. The average age of patients in the high-risk group was significantly (pvalue: 0.001) higher than the low-risk group. There was a significant correlation between MID-right ventricle and pulmonary artery pressure with the severity of embolism, so that mid-right ventricle and pulmonary artery pressure in the high-risk group were significantly higher (p-value: 0.000) than in the low-risk group. Also, the severity of PE was significantly related to RV size (P = 0.026) and function (P = 0.038).Conclusion: RV size, function, and dilatation, and pulmonary artery pressure variated significantly in different severities of PE.","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"23 4","pages":"364-370"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464831/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Chest Physiotherapy on the Clinical Outcomes of COVID-19 Patients. 胸部物理治疗对新冠肺炎患者临床结局的影响

Tanaffos Pub Date : 2024-04-01

Reza Moradi-Azhgil, Neda Sayadi, Shayesteh Haghighi, Parya Moradi

{"title":"Effect of Chest Physiotherapy on the Clinical Outcomes of COVID-19 Patients.","authors":"Reza Moradi-Azhgil, Neda Sayadi, Shayesteh Haghighi, Parya Moradi","doi":"","DOIUrl":"","url":null,"abstract":"Background: The novel coronavirus 2019 primarily affects the respiratory system and may lead to respiratory failure and the need for intubation. This study aimed to investigate the effect of chest physiotherapy on the clinical outcomes of patients with COVID-19.Materials and methods: This randomized clinical trial was performed in 2022-2023. The research population included 58 patients with COVID-19 who were hospitalized at Izeh Shohada Hospital, Khuzestan. Patients in the control group received routine care, which included the use of supportive drugs based on the doctor's opinion, oxygen therapy, and nutritional support. The intervention group received chest physiotherapy and breathing exercises for six days. At the end of the third and sixth days, the patients of both groups were evaluated in terms of lung function, respiratory gases, and the length of hospital stay. Moreover, the need for intubation was recorded during study time. Data analysis was done using SPSS version 23 software.Results: In the intervention group, a significant improvement was observed in FVC (P<0.01), FEV1(P<0.01), FEV1/FVC ratio (P<0.01), PaO2 (P<0.01), PaCO2 (P<0.01), and SPO2 (P<0.01) as well as the length of hospital stay (P<0.01) after the intervention. However, no significant difference was observed in the PaO2/FiO2 ratio (P>0.05) and the need for intubation (P>0.05).Conclusion: The results showed that in the new crisis resulting from COVID-19, chest physiotherapy and respiratory exercises could be used as a helpful method in improving lung function, respiratory gases, and reducing the hospital stay in COVID-19 patients.","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"23 4","pages":"392-402"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Predictors of Quality of Life in Patients with Asthma in Ahvaz, Iran. 伊朗阿瓦士哮喘患者生活质量的预测因素

Tanaffos Pub Date : 2024-04-01

Ahmad Tahmasebi Ghorrabi, Hanieh Raji, Amin Torabipour, Seydeh Maryam Mousavi, Zahara Oraman, Parisa Badiei Nasab, Mohammad Hosein Haghighizadeh

{"title":"Predictors of Quality of Life in Patients with Asthma in Ahvaz, Iran.","authors":"Ahmad Tahmasebi Ghorrabi, Hanieh Raji, Amin Torabipour, Seydeh Maryam Mousavi, Zahara Oraman, Parisa Badiei Nasab, Mohammad Hosein Haghighizadeh","doi":"","DOIUrl":"","url":null,"abstract":"Background: Asthma impacts the quality of life (QOL) of patients and their families. The magnitude of this morbidity is influenced by several factors, including age, disease duration, and others. This study was conducted to determine the predictors of quality of life in patients with asthma in Ahvaz, Iran.Materials and methods: This cross-sectional study was conducted among patients referred to the pulmonary clinics of Imam Khomeini and Golestan hospitals in Ahvaz in 2022. The quality of life was assessed using the SF-36v2 questionnaire. The effect of socio-demographic characteristics on quality-of-life scores was examined by t-test, one-way variance (ANOVA), Pearson's correlation coefficient, and regression models.Results: From a total of 204 studied asthmatic patients, the average age of patients was 43.22±15.17 years. The average QOL in patients was 57.69±22.97. Physical role and social functioning had the lowest and highest mean scores among SF-36 dimensions, respectively. A significant difference was observed between the average QOL score and the variables of age, gender, education level, employment status, illness costs, illness severity, daily exercise, and number of visits (P<0.05). Most clinical, socio-demographic, and economic variables were predictors of SF-36, PCS, MCS, and QOL dimensions (P<0.05).Conclusion: This study showed that the quality of life in asthmatic patients is affected by the severity of the disease, number of visits, age, sex, and education. By performing appropriate interventions on social and economic factors, the quality of life of asthmatic patients can be improved.","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"23 4","pages":"376-391"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464841/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Thymoquinone Targeting T Helper 2 Cytokines in Animal Models of Asthma: A Systematic Review. 百里醌靶向辅助性T 2细胞因子在哮喘动物模型中的作用：系统综述。

Tanaffos Pub Date : 2024-04-01

Hanieh Tahermohammadi, Ali Abdolahinia, Mohammad Ali Tahermohammadi, Mohammad Ali Hojjati Kermani, Babak Daneshfard, Ali Akbar Velayati

{"title":"Thymoquinone Targeting T Helper 2 Cytokines in Animal Models of Asthma: A Systematic Review.","authors":"Hanieh Tahermohammadi, Ali Abdolahinia, Mohammad Ali Tahermohammadi, Mohammad Ali Hojjati Kermani, Babak Daneshfard, Ali Akbar Velayati","doi":"","DOIUrl":"","url":null,"abstract":"Background: Thymoquinone (TQ) is one of the active components of Nigella sativa L. It has therapeutic properties in allergic diseases, such as the antihistamine effect on the airways of patients with asthma and inhibition of inflammatory changes. This systematic review was conducted to investigate the effect of TQ on T helper 2 (Th2) cytokines, including IL-4, IL-5, and IL-13, in the treatment of animal models of asthma.Materials and methods: A comprehensive article search was conducted using Web of Science, Scopus, and PubMed to find articles published until 2022 regarding the efficacy of TQ in treating animal models of asthma. We found 399 articles in Scopus, 927 in Web of Science, and 790 in PubMed, from a total number of 2116 articles. After deleting duplicate articles, we read the remaining 1126 titles and abstracts. Finally, 37 articles were selected for full reading. After excluding papers without full text, duplicates, letters, case studies, and those whose topic did not meet the criteria of this study, 8 articles remained. In the manual search, we did not find any deviating articles from the systematic search.Results: Our results showed that TQ had a significant effect on the reduction of Th2 cytokines, including IL-4, IL-5, and IL-13, in animal models of asthma.Conclusion: Current evidence shows the anti-inflammatory effects of TQ on Th2 cytokines, but its association with the reduction of Th2 cytokines in animal models of asthma needs further studies.","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"23 4","pages":"334-340"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464842/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The History of Anesthesia and Anesthesiologists in Iran. 伊朗的麻醉史和麻醉师。

Tanaffos Pub Date : 2024-04-01

Alireza Salimi, Makan Sadr, Babak Daneshfard

{"title":"The History of Anesthesia and Anesthesiologists in Iran.","authors":"Alireza Salimi, Makan Sadr, Babak Daneshfard","doi":"","DOIUrl":"","url":null,"abstract":"The evolution of anesthesia and anesthesiology represents a pivotal chapter in the history of medical science, significantly enhancing patient care and surgical outcomes. General anesthesia, defined as the deliberate induction of a temporary state of pain relief, muscle paralysis, memory impairment, and unconsciousness, has revolutionized medical procedures by inhibiting the normal functioning of the central nervous system. In Iran, the journey of anesthesiology began with early contributions from ancient scholars and practitioners, whose innovative techniques laid the groundwork for future advancements. The field witnessed significant progress in the mid-20th century, aligning with global developments in medical science. Initially focused on intraoperative care, anesthesiology in Iran expanded to encompass preoperative evaluations, postoperative assessments, and comprehensive patient monitoring, addressing complications related to surgery and anesthesia. In addition to analyzing the evolution of anesthesiology from solely surgical intervention to a broader field encompassing preoperative evaluation, postoperative care, and critical care management, this paper addresses the challenges and opportunities facing anesthesia and anesthesiology in Iran, including the need for wider access to safe and reliable services and the integration of advanced technologies.","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"23 4","pages":"324-333"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464840/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sonography Guided Evaluation of Hemodynamic Indices in Critically Ill Patients Suffering from AKI during CRRT. 超声引导下急性肾损伤危重患者CRRT期间血流动力学指标的评价。

Tanaffos Pub Date : 2024-04-01

Morteza Foroumandi, Seyedpouzhia Shojaei, Batoul Khoundabi, Farin Rashid Farokhi, Mehrdad Bakhshayesh Karam, Ahsina Jahan Lopa, Hasan Safdari, Ranajit Chatterjee, Seyed Mohammad Reza Hashemian

{"title":"Sonography Guided Evaluation of Hemodynamic Indices in Critically Ill Patients Suffering from AKI during CRRT.","authors":"Morteza Foroumandi, Seyedpouzhia Shojaei, Batoul Khoundabi, Farin Rashid Farokhi, Mehrdad Bakhshayesh Karam, Ahsina Jahan Lopa, Hasan Safdari, Ranajit Chatterjee, Seyed Mohammad Reza Hashemian","doi":"","DOIUrl":"","url":null,"abstract":"Background: Recent pieces of evidence have shown higher efficacy of continuous renal replacement therapy (CRRT) with regard to improvement of survival in critically ill patients by maintaining hemodynamic stability. The present study aimed to assess hemodynamic conditions before and after CRRT with the point-of-care approach.Materials and methods: The present interventional before-after study was performed on 20 critically ill patients with unstable hemodynamic status admitted to the ICU at Masih-e-Daneshvari Hospital in Tehran in 2019. They were candidate for CRRT due to acute kidney injury (AKI). The main pointed parameters for assessment before and after CRRT included heart rate, mean arterial pressure (MAP), central vein pressure (CVP), the carotid corrected flow time (FTc), carotid peak systolic velocity (PSV), inferior vena cava collapsibility (cIVC), resistive index (RI), and inferior vena cava (IVC) size and distensibility aided by ultrasonography.Results: Regarding the changes in ultrasonography parameters after CRRT, except for carotid PSV, heart rate, and carotid area, other parameters showed a significant change. In this regard, IVC size, FTc, MAP, CVP, internal jugular vein (IJV) area, and RI all significantly decreased while IVC distensibility index significantly increased following CRRT. Similar changes were revealed in the subgroup of patients with hypotension, but in another subgroup without hypotension, the decrease in carotid PSV was also meaningful.Conclusion: Applying CRRT in AKI patients in critically ill situations can effectively balance cardiovascular and hemodynamic parameters and thus lead to more appropriate survival.","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"23 4","pages":"341-348"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hekmat-Based Medicine Approach in Masih Daneshvari Referral Pulmonary Hospital. Masih Daneshvari转诊肺部医院基于hekmat的医学方法。

Tanaffos Pub Date : 2024-04-01

Ali Akbar Velayati, Mohammad Varahram, Elham Ghazanchaei

引用次数: 0

Methylprednisolone-Induced Hyperlactatemia: A Case Report. 甲强的松龙致高乳酸血症1例报告。

Tanaffos Pub Date : 2024-04-01

Sarah Saenz, Anila Bhatti, Aaron Beck, Micah T Long

{"title":"Methylprednisolone-Induced Hyperlactatemia: A Case Report.","authors":"Sarah Saenz, Anila Bhatti, Aaron Beck, Micah T Long","doi":"","DOIUrl":"","url":null,"abstract":"Lactic acidosis is commonly encountered in critical care and can be a harbinger of life-threatening conditions and end-organ ischemia. Importantly, however, other etiologies of lactic acidosis exist. We review the first case of methylprednisolone-induced lactic acidosis in a previously healthy patient who suffered from traumatic spinal cord injury (SCI). A 19-year-old female presented to a level 1 trauma center after a fall resulted in lower extremity paralysis. After imaging revealed a chance fracture dislocation of T7-8 along with spinal cord compromise and swelling, the patient underwent emergent T5-T11 instrumented fusion. Postoperatively, she was given high-dose methylprednisolone in hopes of improving neurologic outcome; soon after administration, she developed lactic acidosis. After workup ruled out hypoperfusion and type A lactic acidosis, we determined that methylprednisolone likely induced non-ischemic, type B, lactic acidosis. The lactate quickly returned to baseline after steroid discontinuation. It is important for clinicians to consider type B lactic acidosis in the ICU in patients with persistent lactic acidosis after tissue hypoperfusion has been ruled out.","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"23 4","pages":"409-412"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464832/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Case of Pneumothorax Following Radiation Therapy for Small Cell Lung Cancer in a Patient with Scleroderma-ILD. 硬皮病- ild小细胞肺癌放疗后发生气胸1例。

Tanaffos Pub Date : 2024-04-01

Fatih Uzer, Aykut Cilli

{"title":"A Case of Pneumothorax Following Radiation Therapy for Small Cell Lung Cancer in a Patient with Scleroderma-ILD.","authors":"Fatih Uzer, Aykut Cilli","doi":"","DOIUrl":"","url":null,"abstract":"Connective tissue diseases, particularly scleroderma, pose a heightened risk for the development of malignancies such as breast and lung cancer. Stereotactic Body Radiation Therapy (SBRT) has emerged as an effective treatment modality for various cancers, including lung and breast cancers, due to its curative potential, especially for localized extracranial tumors. A 69-year-old patient with a 30-pack-year smoking history presented with shortness of breath and bilateral diffuse rales on chest auscultation during the outpatient clinic visit. Notably, the patient had not received scleroderma treatment for a year at the time of radiation therapy. Despite the recognized sensitivity of the lungs to radiotherapy, the occurrence of pneumothorax and pneumomediastinum following SBRT in this case raises concerns about the potential complications in scleroderma-ILD patients with lung cancer. This report underscores the need for comprehensive risk assessment and careful consideration of alternative treatment strategies for lung cancer in scleroderma patients, particularly those with pre-existing lung involvement. Further research is warranted to elucidate the mechanisms and risk factors associated with complications following radiotherapy in this patient population, guiding clinicians in optimizing therapeutic approaches for improved outcomes.","PeriodicalId":22247,"journal":{"name":"Tanaffos","volume":"23 4","pages":"413-416"},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464833/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

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