Tetrahedron, asymmetry最新文献_第6页

Applications of Danishefsky’s dienes in asymmetric Oxo-Diels-Alder reactions Danishefsky二烯在不对称氧- diels - alder反应中的应用

Tetrahedron, asymmetry Pub Date : 2017-11-15 DOI: 10.1016/j.tetasy.2017.10.030

Afsaneh Taheri kal Koshvandi, Majid M. Heravi

引用次数: 18

Recent developments in the enantioselective synthesis of polyfunctionalized pyran and chromene derivatives 多功能化吡喃和铬胺衍生物对映选择性合成的最新进展

Tetrahedron, asymmetry Pub Date : 2017-11-15 DOI: 10.1016/j.tetasy.2017.10.020

Kamal Usef Sadek , Ramadan Ahmed H. Mekheimer , Mohamed Abd-Elmonem , Afaf Abdel-Hameed , Mohamed Hilmy Elnagdi

{"title":"Recent developments in the enantioselective synthesis of polyfunctionalized pyran and chromene derivatives","authors":"Kamal Usef Sadek , Ramadan Ahmed H. Mekheimer , Mohamed Abd-Elmonem , Afaf Abdel-Hameed , Mohamed Hilmy Elnagdi","doi":"10.1016/j.tetasy.2017.10.020","DOIUrl":"10.1016/j.tetasy.2017.10.020","url":null,"abstract":"<div>Recent developments in the synthesis of 4H- and 2H-pyrans as well as structurally related chromene derivatives that have enabled the enantioselective synthesis of these scaffolds have been surveyed. The role of chiral catalysts in orienting initial reactions of active methylenes, methines and methyl ketones, to unsaturated ketones and nitriles in multi-component reactions or Friedel–Craft alkylations of phenols is discussed to show their involvement in transition states leading to end products. Chromene synthesis via [4+2] cycloadditions, [3+3] and [4+2] annulations as well as ring opening and recyclization leading to high enantio- and diasteroselectivity is also demonstrated. The enantioselectivity in such catalytic asymmetric reactions despite starting with non-chiral starting materials is discussed. On the other hand, in surveying ring opening and recyclization, the starting materials are chiral and the chiral center was not part of the reaction leading to the final product.</div>","PeriodicalId":22237,"journal":{"name":"Tetrahedron, asymmetry","volume":"28 11","pages":"Pages 1462-1485"},"PeriodicalIF":0.0,"publicationDate":"2017-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.tetasy.2017.10.020","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86291472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 22

Immobilization of Lecitase® ultra on recyclable polymer support: application in resolution of trans-methyl (4-methoxyphenyl)glycidate in organic solvents Lecitase®ultra在可回收聚合物载体上的固定化:在有机溶剂中反式甲基(4-甲氧基苯基)甘氨酸酯溶解中的应用

Tetrahedron, asymmetry Pub Date : 2017-11-15 DOI: 10.1016/j.tetasy.2017.10.006

Thenkrishnan Kumaraguru, Tirunagari Harini, Shalini Basetty

引用次数: 11

An asymmetric synthesis of (+)-monomorine I (+)-单摩尔胺I的不对称合成

Tetrahedron, asymmetry Pub Date : 2017-11-15 DOI: 10.1016/j.tetasy.2017.09.008

Masaki Asai , Yukiko Takemoto , Ayaka Deguchi , Yasunao Hattori , Hidefumi Makabe

引用次数: 7

Concise asymmetric synthesis of the sex pheromone of the tea tussock moth 茶柞蛾性信息素的简明不对称合成

Tetrahedron, asymmetry Pub Date : 2017-11-15 DOI: 10.1016/j.tetasy.2017.09.007

Zhi-Feng Sun , Lu-Nan Zhou , Yifei Meng , Tao Zhang , Zhen-Ting Du , Huaiji Zheng

引用次数: 9

Highly enantioselective organocatalysis of the Michael addition of benzyloxyacetaldehyde to nitroolefins 苯氧乙醛对硝基烯烃加成反应的高对映选择性有机催化

Tetrahedron, asymmetry Pub Date : 2017-11-15 DOI: 10.1016/j.tetasy.2017.09.018

Sripragna Burugupalli, Yupu Qiao, Allan D. Headley

引用次数: 1

Cumulative author index 累计作者索引

Tetrahedron, asymmetry Pub Date : 2017-11-15 DOI: 10.1016/S0957-4166(17)30519-0

引用次数: 0

Review on asymmetric synthetic methodologies for chiral isoquinuclidines; 2008 to date 手性异喹啉类化合物的不对称合成方法综述2008年至今

Tetrahedron, asymmetry Pub Date : 2017-11-15 DOI: 10.1016/j.tetasy.2017.10.013

Muhammad Faisal , Danish Shahzad , Aamer Saeed , Bhajan Lal , Shomaila Saeed , Fayaz Ali Larik , Pervaiz Ali Channar , Parvez Ali Mahesar , Jamaluddin Mahar

{"title":"Review on asymmetric synthetic methodologies for chiral isoquinuclidines; 2008 to date","authors":"Muhammad Faisal , Danish Shahzad , Aamer Saeed , Bhajan Lal , Shomaila Saeed , Fayaz Ali Larik , Pervaiz Ali Channar , Parvez Ali Mahesar , Jamaluddin Mahar","doi":"10.1016/j.tetasy.2017.10.013","DOIUrl":"10.1016/j.tetasy.2017.10.013","url":null,"abstract":"<div>Isoquinuclidines constitute the central structural nucleus of numerous biologically active natural products, for example, iboga alkaloids such as ibogamine and catharanthine as well as non-indole-containing alkaloids such as the dioscorine and the cannivonines. Furthermore, in medicinal and pharmaceutical chemistry, the isoquinuclidine core is commonly employed as a rigid azabicyclic scaffold, thus providing significant precursors in the synthesis of numerous valuable alkaloids. Summarizing well-organized approaches to access the chiral isoquinuclidine structural centerpiece signifies a significant endeavor not only for developing biologically active natural products but also enhancing biological researches that can lead to possible drug discovery. Over time, the values and methodologies for the asymmetric synthesis of chiral isoquinuclidines are increasing; hence to advance asymmetric synthesis, this review combines and discusses the pros and cons of each synthesis techniques from 2008. This review should be helpful for promoting further developments of asymmetric synthetic methodologies and for medicinal chemistry.</div>","PeriodicalId":22237,"journal":{"name":"Tetrahedron, asymmetry","volume":"28 11","pages":"Pages 1445-1461"},"PeriodicalIF":0.0,"publicationDate":"2017-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.tetasy.2017.10.013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73490549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

Synthesis of the four enantiomers of diethyl 1,2-di(N-Boc-amino)propylphosphonates 1,2-二(n - boc -氨基)丙基膦酸二乙酯四个对映体的合成

Tetrahedron, asymmetry Pub Date : 2017-11-15 DOI: 10.1016/j.tetasy.2017.09.003

Iwona E. Głowacka, Dorota G. Piotrowska, Andrzej E. Wróblewski, Aleksandra Trocha

引用次数: 4

Tartaric acid-derived chiral phosphite-type P,N-ligands: behavioural features in Pd-catalyzed asymmetric transformations 酒石酸衍生的手性磷酸盐型P, n配体:pd催化不对称转化的行为特征

Tetrahedron, asymmetry Pub Date : 2017-11-15 DOI: 10.1016/j.tetasy.2017.09.011

Konstantin N. Gavrilov , Sergey V. Zheglov , Ilya V. Chuchelkin , Marina G. Maksimova , Ilya D. Firsin , Andrew N. Fitch , Vladimir V. Chernyshev , Alexander V. Maximychev , Alexander M. Perepukhov

{"title":"Tartaric acid-derived chiral phosphite-type P,N-ligands: behavioural features in Pd-catalyzed asymmetric transformations","authors":"Konstantin N. Gavrilov , Sergey V. Zheglov , Ilya V. Chuchelkin , Marina G. Maksimova , Ilya D. Firsin , Andrew N. Fitch , Vladimir V. Chernyshev , Alexander V. Maximychev , Alexander M. Perepukhov","doi":"10.1016/j.tetasy.2017.09.011","DOIUrl":"10.1016/j.tetasy.2017.09.011","url":null,"abstract":"<div>A practical synthesis of new phosphoramidite, phosphite and diamidophosphite P,N-ligands derived from (R,R)-tartaric acid was carried out. A study of these chiral inducers showed them to provide up to 93% ee in the Pd-catalyzed asymmetric allylations of (E)-1,3-diphenylallyl acetate, up to 84% ee in the Pd-catalyzed asymmetric alkylation of cinnamyl acetate with ethyl 2-oxocyclohexane-1-carboxylate and up to 63% ee in the Pd-catalyzed desymmetrization of N,N′-ditosyl-meso-cyclopent-4-ene-1,3-diol biscarbamate. The effects of the structural modules, such as the nature of the phosphorus-containing ring or exocyclic substituent as well as of the nature of palladium source on the catalytic activity and enantioselectivity were investigated.</div>","PeriodicalId":22237,"journal":{"name":"Tetrahedron, asymmetry","volume":"28 11","pages":"Pages 1633-1643"},"PeriodicalIF":0.0,"publicationDate":"2017-11-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.tetasy.2017.09.011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73053939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8