Concise asymmetric synthesis of the sex pheromone of the tea tussock moth

Abstract

A concise asymmetric total synthesis of the sex pheromone of the tea tussock moth has been achieved from commercially available starting materials. The chiral moiety was introduced by Evans’ template and the key CC bond construction was accomplished through Julia-Kocienski coupling and Wittig olefination. The salient characteristic of our synthetic route is that it is protecting a group free.