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"Surgical Outcomes After Preoperative Embolization in Hypervascular Spinal Metastases: A Propensity Scored Study of 191 Patients" by Pierik et al. 关于Pierik等人“191例高血管性脊柱转移瘤术前栓塞后的手术结果:倾向评分研究”的致编辑信。
IF 3.5 2区 医学
Spine Pub Date : 2026-06-01 Epub Date: 2025-11-03 DOI: 10.1097/BRS.0000000000005556
Rino Matsuo, Yu Toda, Fumihiro Inoue, Hirohito Hirata, Tomohito Yoshihara, Masatsugu Tsukamoto, Tadatsugu Morimoto
{"title":"\"Surgical Outcomes After Preoperative Embolization in Hypervascular Spinal Metastases: A Propensity Scored Study of 191 Patients\" by Pierik et al.","authors":"Rino Matsuo, Yu Toda, Fumihiro Inoue, Hirohito Hirata, Tomohito Yoshihara, Masatsugu Tsukamoto, Tadatsugu Morimoto","doi":"10.1097/BRS.0000000000005556","DOIUrl":"10.1097/BRS.0000000000005556","url":null,"abstract":"","PeriodicalId":22193,"journal":{"name":"Spine","volume":" ","pages":"E294"},"PeriodicalIF":3.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147634355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Operative Order on Postoperative Outcomes in Patients Undergoing Lumbar Fusion and Total Hip Arthroplasty: A Systematic Review and Meta-Analysis. 手术顺序对腰椎融合术和全髋关节置换术患者术后预后的影响:一项系统回顾和荟萃分析。
IF 3.5 2区 医学
Spine Pub Date : 2026-06-01 Epub Date: 2026-03-24 DOI: 10.1097/BRS.0000000000005700
Nadir Al-Saidi, Neil Al-Saidi, Ryan Nguyen, Asimina Dominari, Alison Reilly, Dina Mohammed, Mohamad Bydon
{"title":"Impact of Operative Order on Postoperative Outcomes in Patients Undergoing Lumbar Fusion and Total Hip Arthroplasty: A Systematic Review and Meta-Analysis.","authors":"Nadir Al-Saidi, Neil Al-Saidi, Ryan Nguyen, Asimina Dominari, Alison Reilly, Dina Mohammed, Mohamad Bydon","doi":"10.1097/BRS.0000000000005700","DOIUrl":"10.1097/BRS.0000000000005700","url":null,"abstract":"<p><strong>Study design: </strong>Systematic review and meta-analysis.</p><p><strong>Objective: </strong>To assess how operative order affects clinical outcomes and complications in patients with concomitant lumbar spinal and hip pathologies.</p><p><strong>Summary of background data: </strong>Concomitant lumbar spinal and hip pathologies are becoming increasingly prevalent in the growing population. Determining the optimal operative order for surgical treatment remains challenging, particularly when comparing spine arthrodesis followed by hip arthroplasty (SAHA) with hip arthroplasty followed by spine arthrodesis (HASA). Prior studies report conflicting results regarding outcomes and complications.</p><p><strong>Methods: </strong>A comprehensive literature search was performed to identify studies reporting on postoperative outcomes and complications in patients with concomitant lumbar spinal and hip pathologies. Random-effects model meta-analysis of pooled outcomes was performed comparing operative order groups (SAHA and HASA), with postoperative complications and revisions being our primary endpoints.</p><p><strong>Results: </strong>A total of 22 studies, yielding 161,326 patients who received surgical treatment for concomitant lumbar spinal and hip pathologies, were included. The majority of patients underwent SAHA (pooled estimate: 88.4%, 95% CI: 76.9-96.3%, P =0.01). Females comprised 56.1% (95% CI: 49.2-62.8%) of the study population. The mean age was 70.6±6.4 years, and the mean follow-up duration was 2.6±2.1 years. The mean number of treated levels was 2.1±1.4. No significant differences were noted between the SAHA and HASA groups with respect to complications, including hip dislocation ( P =0.7), mechanical loosening ( P =0.8), periprosthetic fractures ( P =0.7), deep venous thrombosis (DVT) ( P =0.8), and infection ( P =0.9). Revisions were required in 3.6% of patients in the SAHA group (95% CI: 2.5-4.9%) and 2.6% of patients in the HASA group (95% CI: 0.5-6.2%, P =0.5).</p><p><strong>Conclusion: </strong>Among patients surgically treated for concomitant lumbar spinal and hip pathologies, SAHA was significantly more commonly performed than HASA. Our analysis shows that postoperative complications and revisions did not significantly differ depending on operative order.</p>","PeriodicalId":22193,"journal":{"name":"Spine","volume":" ","pages":"813-822"},"PeriodicalIF":3.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147522151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor "Pelvic Incidence Changes in Patients With Adult Spinal Deformity Following S2AI Fixation: Is the Hip Joint Involved?" 致编辑的信“S2AI固定后成人脊柱畸形患者骨盆发生率的变化:是否涉及髋关节?”
IF 3.5 2区 医学
Spine Pub Date : 2026-06-01 Epub Date: 2026-03-27 DOI: 10.1097/BRS.0000000000005703
Soner Kocak
{"title":"Letter to the Editor \"Pelvic Incidence Changes in Patients With Adult Spinal Deformity Following S2AI Fixation: Is the Hip Joint Involved?\"","authors":"Soner Kocak","doi":"10.1097/BRS.0000000000005703","DOIUrl":"10.1097/BRS.0000000000005703","url":null,"abstract":"","PeriodicalId":22193,"journal":{"name":"Spine","volume":" ","pages":"823-824"},"PeriodicalIF":3.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk Factors for Postoperative Cognitive Dysfunction Following Multilevel Lumbar Spinal Fusion. 多节段腰椎融合术后认知功能障碍的危险因素。
IF 3.5 2区 医学
Spine Pub Date : 2026-06-01 Epub Date: 2025-06-09 DOI: 10.1097/BRS.0000000000005420
Mladen Djurasovic, Steven D Glassman, Justin Mathew, Jeffrey L Gum, Desiree Chappell, Christy L Daniels, Colleen Mahoney, Morgan E Brown, Benjamin A Kostic, Leah Y Carreon
{"title":"Risk Factors for Postoperative Cognitive Dysfunction Following Multilevel Lumbar Spinal Fusion.","authors":"Mladen Djurasovic, Steven D Glassman, Justin Mathew, Jeffrey L Gum, Desiree Chappell, Christy L Daniels, Colleen Mahoney, Morgan E Brown, Benjamin A Kostic, Leah Y Carreon","doi":"10.1097/BRS.0000000000005420","DOIUrl":"10.1097/BRS.0000000000005420","url":null,"abstract":"<p><strong>Study design: </strong>Retrospective observational cohort.</p><p><strong>Objectives: </strong>To determine the incidence of and risk factors for postoperative cognitive dysfunction (POCD) following multilevel spine fusion.</p><p><strong>Summary of background data: </strong>POCD is a serious, common and under-recognized complication in elderly patients undergoing surgery. Risk factors for POCD vary in the literature and include preoperative as well as intraoperative factors.</p><p><strong>Materials and methods: </strong>A retrospective cohort of 566 thoracolumbar fusion cases with a minimum of 4 surgical levels were identified. A chart review was performed for the occurrence of POCD and known risk factors for POCD. Anesthetic and surgical data included operative time, fluid volume, blood loss, blood product replacement, and use of vasopressors. Arterial line-based mean arterial pressure (MAP) data were collected at 1-minute intervals, and the cumulative duration of MAP <65 mm Hg was recorded. Univariate and multivariate statistical analysis was used to investigate the relationship between demographic, preoperative and intraoperative risk factors, and the occurrence of POCD.</p><p><strong>Results: </strong>Overall, 70 out of 566 patients (12.4%) experienced POCD described most commonly as encephalopathy (57, 81%), delirium (8, 11%), hallucinations (3, 4%), and altered mental status (2, 3%). Patients who developed POCD were older (68.7 yr vs . 59.6 yr, P <0.001), had a worse ASA scores (2.9 vs . 2.7, P =0.004), higher BMI (32.0 vs . 30.0, P =0.007), a higher incidence of diabetes (31% vs . 16%, P =.002), and sleep apnea (47% vs . 28%, P =0.002). Intraoperatively, patients who experienced POCD had greater fluid shifts and hemodynamic instability in terms of blood loss (800 mL vs . 660 mL, P =0.047), blood transfusion (350 mL vs . 201 mL, P =0.014), minutes of intraoperative hypotension (11.6 vs . 6.4, P =0.043) and vasopressor use (10604 mcg vs . 6823 mcg, P =0.029).</p><p><strong>Conclusions: </strong>Postoperative cognitive dysfunction is associated with age, preoperative comorbidities, and greater intraoperative hemodynamic instability. These factors present targets for optimization before surgery to lower the incidence of postoperative cognitive dysfunction.</p>","PeriodicalId":22193,"journal":{"name":"Spine","volume":" ","pages":"808-812"},"PeriodicalIF":3.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Three-Dimensional Quantitative Analysis of Spinal Cord Dynamics During Anterior Cervical Decompression and Fusion: New Insights Using Intraoperative Ultrasonography. 颈椎前路减压融合术中脊髓动力学的三维定量分析:术中超声检查的新见解。
IF 3.5 2区 医学
Spine Pub Date : 2026-06-01 Epub Date: 2025-08-19 DOI: 10.1097/BRS.0000000000005473
Yohei Ito, Hisanori Mihara, Yasunori Tatara, Takanori Niimura, Akira Sakaguchi, Yasuteru Yamaguchi, Tetsuhiko Inoue, Hiroki Katayama, Hideo Mitsui, Hiroto Kono, Yutaka Inaba
{"title":"Three-Dimensional Quantitative Analysis of Spinal Cord Dynamics During Anterior Cervical Decompression and Fusion: New Insights Using Intraoperative Ultrasonography.","authors":"Yohei Ito, Hisanori Mihara, Yasunori Tatara, Takanori Niimura, Akira Sakaguchi, Yasuteru Yamaguchi, Tetsuhiko Inoue, Hiroki Katayama, Hideo Mitsui, Hiroto Kono, Yutaka Inaba","doi":"10.1097/BRS.0000000000005473","DOIUrl":"10.1097/BRS.0000000000005473","url":null,"abstract":"<p><strong>Study design: </strong>Multicenter retrospective observational study.</p><p><strong>Objective: </strong>To quantitatively evaluate spinal cord pulsatile motion during anterior cervical decompression and fusion (ACDF) and identify factors affecting spinal cord dynamics.</p><p><strong>Background: </strong>Intraoperative ultrasonography is useful to assess neural decompression during cervical spinal surgery. While spinal cord pulsation has been qualitatively evaluated, detailed quantitative analyses of three-dimensional spinal cord motion are lacking.</p><p><strong>Materials and methods: </strong>One hundred nine intervertebral spaces of 50 patients (32 men and 18 women; mean age: 66.9±11.6 yr) who underwent ACDF were evaluated. Two-dimensional video measurement software was used to quantify anteroposterior pulsation and craniocaudal sliding motion of the spinal cord in intraoperative ultrasound recordings. In addition, correlations between cervical alignment parameters (C2-7 and O-C2 angles) and spinal cord pulsation characteristics were analyzed.</p><p><strong>Results: </strong>Craniocaudal sliding motion was significantly greater than anteroposterior pulsation in both amplitude (1.09±0.93 vs. 0.34±0.21 mm, P <0.001) and velocity (16.75±11.12 vs. 5.39±4.26 mm/s, P <0.001). Directional analysis revealed greater velocities from posterior to anterior than from anterior to posterior (5.30±5.12 vs. 4.47±4.12 mm/s, P =0.00489) and from cranial to caudal than from caudal to cranial (16.53±11.10 vs. 11.59±7.71 mm/s, P <0.001). The maximum anteroposterior amplitude was significantly greater at the C4/5 level than at the C3/4 or C6/7 level ( P =0.0027). The C2-7 angle showed a moderate positive correlation with craniocaudal sliding parameters (amplitude: r =0.467, P <0.001; velocity: r =0.41, P <0.001) and a weak positive correlation with anteroposterior pulsatile parameters.</p><p><strong>Conclusion: </strong>This first quantitative three-dimensional analysis of spinal cord motion during ACDF revealed that craniocaudal sliding motion exceeded anteroposterior pulsation. The preferential direction from cranial to caudal indicated the brain pulsation to be the major origin. The C4/5 level exhibited maximum anteroposterior motion, which may be related to C5 palsy pathophysiology. Increased cervical lordosis promoted both types of motion, particularly craniocaudal sliding. These findings may guide intraoperative neural assessments during cervical decompression procedures.</p>","PeriodicalId":22193,"journal":{"name":"Spine","volume":" ","pages":"E268-E276"},"PeriodicalIF":3.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144875333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
L1-S1 Posterior Paraspinal Muscle Fatty Infiltration and a Radiomics Signature Predict Prolonged Length of Stay After Lumbar Spine Surgery in Older Adults. L1-S1后棘旁肌脂肪浸润和放射组学特征预测老年人腰椎手术后住院时间延长。
IF 3.5 2区 医学
Spine Pub Date : 2026-06-01 Epub Date: 2026-02-25 DOI: 10.1097/BRS.0000000000005667
MaChao Guo, Shuaikang Wang, Xiangyu Li, Yuxi Liu, Shibao Lu
{"title":"L1-S1 Posterior Paraspinal Muscle Fatty Infiltration and a Radiomics Signature Predict Prolonged Length of Stay After Lumbar Spine Surgery in Older Adults.","authors":"MaChao Guo, Shuaikang Wang, Xiangyu Li, Yuxi Liu, Shibao Lu","doi":"10.1097/BRS.0000000000005667","DOIUrl":"10.1097/BRS.0000000000005667","url":null,"abstract":"<p><strong>Study design: </strong>Retrospective cohort study.</p><p><strong>Objective: </strong>To determine whether multilevel L1 to S1 paraspinal muscle fatty infiltration (FI) and a posterior paraspinal radiomics signature improve prediction of prolonged length of stay (LOS) after lumbar spine surgery in geriatric patients.</p><p><strong>Methods: </strong>We retrospectively included 248 patients aged older than or equal to 75 years undergoing open posterior transforaminal lumbar interbody fusion (TLIF) with preoperative axial T2-weighted MRI covering L1 to S1. Paraspinal muscles were segmented (MuscleMap) to derive global L1 to S1 fatty infiltration (all muscle FI) and CSA/BMI. A posterior paraspinal radiomics score (RadScore) was developed from multifidus+erector spinae radiomics features using L1-penalized logistic regression within leakage-free nested cross-validation (outer five-fold; inner five-fold). Prolonged LOS was defined as LOS ≥16 days (75th percentile). Discrimination (AUC), calibration, and clinical utility (DCA) were assessed using out-of-fold predictions; bootstrap 95% CIs were reported.</p><p><strong>Results: </strong>Prolonged LOS occurred in 62/248 (25.0%). Patients with prolonged LOS had lower BMI and a markedly higher prevalence of frailty (Fried ≥3: 87.1% vs. 22.6%). All muscle FI was strongly associated with prolonged LOS after adjustment for clinical and operative factors, and RadScore remained independently associated in radiomics-augmented models; in the combined model, the association for All muscle FI was attenuated, suggesting shared prognostic information between conventional FI and radiomics-derived muscle heterogeneity. In leakage-free nested cross-validation, the clinical model achieved AUC 0.848, which improved to 0.922 after adding All muscle FI, and to 0.933 with RadScore; the combined model yielded the highest AUC (0.936).</p><p><strong>Conclusions: </strong>In older adults undergoing lumbar fusion, global multilevel paraspinal degeneration measured by conventional FI provides major incremental value for predicting prolonged LOS beyond clinical and geriatric factors, whereas posterior paraspinal radiomics offers an additional but more modest improvement. Leakage-free validation supports the robustness and clinical relevance of integrating automated muscle quantification with imaging-based risk stratification.</p>","PeriodicalId":22193,"journal":{"name":"Spine","volume":" ","pages":"E283-E292"},"PeriodicalIF":3.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147390797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does Preoperative Spinal Alignment Influence Surgical Outcomes When Postoperative Alignment and Fixation Strategies Are Matched in ASD Correction? 在ASD矫正中,如果术后脊柱对齐和固定策略相匹配,术前脊柱对齐会影响手术结果吗?
IF 3.5 2区 医学
Spine Pub Date : 2026-06-01 Epub Date: 2026-03-20 DOI: 10.1097/BRS.0000000000005694
Donghua Huang, Zhan Wang, Michael Jian-Wen Chen, Annika Bay, Robert N Uzzo, Gabrielle Dykhouse, Atahan Durbas, Andrea Pezzi, Stephane Owusu-Sarpong, Luis Felipe Colon, Kasra Araghi, Quante Singleton, Farah Musharbash, Sereen Halayqeh, Matthew E Cunningham, Han Jo Kim, Francis C Lovecchio
{"title":"Does Preoperative Spinal Alignment Influence Surgical Outcomes When Postoperative Alignment and Fixation Strategies Are Matched in ASD Correction?","authors":"Donghua Huang, Zhan Wang, Michael Jian-Wen Chen, Annika Bay, Robert N Uzzo, Gabrielle Dykhouse, Atahan Durbas, Andrea Pezzi, Stephane Owusu-Sarpong, Luis Felipe Colon, Kasra Araghi, Quante Singleton, Farah Musharbash, Sereen Halayqeh, Matthew E Cunningham, Han Jo Kim, Francis C Lovecchio","doi":"10.1097/BRS.0000000000005694","DOIUrl":"10.1097/BRS.0000000000005694","url":null,"abstract":"<p><strong>Study design: </strong>Retrospective study.</p><p><strong>Objective: </strong>To evaluate whether the extent of correction influences outcomes following adult spinal deformity (ASD) surgery using a matched-pair analysis.</p><p><strong>Summary of background data: </strong>Alignment targets are often based on achieving absolute values. However, the amount of correction may also influence outcomes. Existing studies are limited by methodological flaws, including multicollinearity and oversimplified modeling of correction.</p><p><strong>Methods: </strong>We included ASD patients who underwent fusion (≥5 levels) with a UIV between T1 and L1 at a single center (2013-2023), with ≥1-year follow-up. Clinical, radiographic, and surgical outcome data were collected. Patients were 1:1 matched based on T4-L1PA mismatch and L1PA offset (±3°), UIV region (upper vs . lower thoracic), and pelvic fixation status (yes/no). Collected variables were then transformed into within-pair differences (Δ) (absolute value) (for continuous/ordinal variables) or classified as concordant/discordant (for binary variables). Outcomes were analyzed as within-pair Δ or concordance using linear or logistic regression, respectively, with within-pair Δpreoperative alignment as the main predictor and clinical covariates adjusted.</p><p><strong>Results: </strong>A total of 114 patients were matched for similar postoperative sagittal alignment and fixation strategy, forming 57 pairs. Among matched pairs, the average within-pair Δpreoperative alignment (reflecting correction magnitude) was as follows: Δmax Cobb 24.2±18.2°, ΔSVA 76.6±53.2 mm, median ΔL1PA offset 5.0° (IQR 2.3-8.2°), and ΔT4-L1PA 6.9±4.7°. No significant associations were observed between within-pair Δpreoperative alignment and ΔODI, Δlength of stay, or Δoperative time. Similarly, within-pair Δpreoperative alignment did not influence binary outcomes including PJK, PJF, reoperation, complications, or discharge disposition.</p><p><strong>Conclusion: </strong>In patients who achieved similar postoperative alignment and fixation strategies, the baseline deformity (or the amount of correction) did not independently affect postoperative outcomes. Achieving target postoperative alignment rather than the extent of correction should remain the primary focus of surgical planning to optimize recovery and reduce complication risk.</p><p><strong>Level of evidence: </strong>Level III.</p>","PeriodicalId":22193,"journal":{"name":"Spine","volume":" ","pages":"761-772"},"PeriodicalIF":3.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147522153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Proposal of a Cervical Sagittal Classification System to Guide Surgical Treatment for Adult Cervical Deformity: A MEANS Cohort Analysis. 颈椎矢状位分类系统指导成人颈椎畸形手术治疗的建议。
IF 3.5 2区 医学
Spine Pub Date : 2026-06-01 Epub Date: 2026-03-23 DOI: 10.1097/BRS.0000000000005692
Zeeshan M Sardar, Roy Miller, Justin L Reyes, Alexandra C Dionne, Josephine R Coury, Fthimnir M Hassan, Jean-Charles Le Huec, Stephane Bourret, Kazuhiro Hasegawa, Hee Kit Wong, Gabriel Liu, Hwee Weng Dennis Hey, Michael P Kelly, Lawrence G Lenke
{"title":"Proposal of a Cervical Sagittal Classification System to Guide Surgical Treatment for Adult Cervical Deformity: A MEANS Cohort Analysis.","authors":"Zeeshan M Sardar, Roy Miller, Justin L Reyes, Alexandra C Dionne, Josephine R Coury, Fthimnir M Hassan, Jean-Charles Le Huec, Stephane Bourret, Kazuhiro Hasegawa, Hee Kit Wong, Gabriel Liu, Hwee Weng Dennis Hey, Michael P Kelly, Lawrence G Lenke","doi":"10.1097/BRS.0000000000005692","DOIUrl":"10.1097/BRS.0000000000005692","url":null,"abstract":"<p><strong>Study design: </strong>Retrospective analysis.</p><p><strong>Objective: </strong>To describe normative cervical sagittal alignment and to propose a classification system to guide clinical assessment and surgical planning.</p><p><strong>Background context: </strong>Optimizing alignment is a key goal of adult cervical deformity (ACD) surgery. The purpose of this study was to understand normative alignment utilizing an asymptomatic adult cohort and to formulate a classification system that would help identify the spinal regions contributing to the cervical deformity.</p><p><strong>Materials and methods: </strong>A total of 468 asymptomatic adults (18-80 yr) from five countries (USA, France, Japan, Singapore, and Tunisia) formed the Multi-Ethnic Alignment Normative Study (MEANS). The C2-C7 sagittal vertical axis (cSVA), T1 slope (T1S), and C2-C7 cervical sagittal angle (CSA; positive=kyphosis, negative=lordosis), and other sagittal parameters were measured. Linear regression was utilized to correlate the C2-C7 CSA to the T1 slope. Thresholds for the C2-C7 sagittal vertical axis and T1 slope were defined as mean+2 SD. Groups were compared using ANOVA with a Tukey post hoc test. χ 2 analysis was used for categorical comparisons.</p><p><strong>Results: </strong>Mean values for C2-C7 cervical sagittal angle were -0.4° (12.7°), T1 slope was 23.0° (7.9°), C2-C7 sagittal vertical axis was 19.1 (9.8). The highest mean segmental Cobb angle was 3.2° (4.8), which was at the C4-C5 segment. The T1S-CSA mismatch was 22.6 (9.4) with an interquartile range of 9.5 to 35.7. Linear regression yielded a formula CSA=-1.1(T1S) + 24.5 ( R2 =0.45, P <.0001) which was simplified to CSA=25-T1S. Four alignment types (1A/1B/2/4) were observed in the MEANS cohort. Type 3 alignment was absent. Types 1A, 1B, 2, and 4 alignment showed significant differences across cervical, thoracic, and global sagittal parameters.</p><p><strong>Conclusion: </strong>We define normative cervical alignment utilizing the MEANS cohort and propose a classification system to identify the spinal region driving the cervical deformity. Types 1A-B represent well-compensated alignment. Types 2 and 3 were considered to have deformities in the cervical spine and thoracolumbar spine, respectively. Type 4 spines have a combined deformity. This can help guide surgeons to determine the appropriate region that should be addressed with surgery.</p>","PeriodicalId":22193,"journal":{"name":"Spine","volume":" ","pages":"773-782"},"PeriodicalIF":3.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147521338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor "A Biomechanical Comparison of Alternatives to C2 Pedicle Screws" by Jian et al . 致编辑的信“C2椎弓根螺钉替代方案的生物力学比较”,作者Qian等。
IF 3.5 2区 医学
Spine Pub Date : 2026-06-01 Epub Date: 2025-10-29 DOI: 10.1097/BRS.0000000000005551
Xin Zhou, Ping Luo, Huasheng Jiang
{"title":"Letter to the Editor \"A Biomechanical Comparison of Alternatives to C2 Pedicle Screws\" by Jian et al .","authors":"Xin Zhou, Ping Luo, Huasheng Jiang","doi":"10.1097/BRS.0000000000005551","DOIUrl":"10.1097/BRS.0000000000005551","url":null,"abstract":"","PeriodicalId":22193,"journal":{"name":"Spine","volume":" ","pages":"E293"},"PeriodicalIF":3.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145393112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Minimum Clinically Important Difference for Oswestry Disability Index Three Months following Lumbar Discectomy is Lower When Anchored to Patient Leg Pain Symptoms. 腰椎切除术后3个月的运动功能障碍指数与患者腿部疼痛症状的最小临床重要差异更低。
IF 3.5 2区 医学
Spine Pub Date : 2026-06-01 Epub Date: 2025-06-12 DOI: 10.1097/BRS.0000000000005427
Issa Mutyaba, Rebekah Kleinsmith, Nicholas Banfield, Haley Puckett, Scott Mitchell, Kevin Mullaney, Brian Cunningham
{"title":"Minimum Clinically Important Difference for Oswestry Disability Index Three Months following Lumbar Discectomy is Lower When Anchored to Patient Leg Pain Symptoms.","authors":"Issa Mutyaba, Rebekah Kleinsmith, Nicholas Banfield, Haley Puckett, Scott Mitchell, Kevin Mullaney, Brian Cunningham","doi":"10.1097/BRS.0000000000005427","DOIUrl":"10.1097/BRS.0000000000005427","url":null,"abstract":"<p><strong>Study design: </strong>Retrospective case series.</p><p><strong>Objective: </strong>The primary objective of this study is to assess the change in patient-reported outcomes from baseline to 3 months following lumbar discectomy for lumbar disc herniation.</p><p><strong>Summary of background data: </strong>Delayed surgical intervention may result in worse patient-reported outcomes. Patient-reported outcome measures (PROMs) such as the Oswestry Disability Index (ODI) and Visual Analog Scale (VAS) are essential tools for assessing care for patients with low back pain and are widely used to track outcomes following discectomy.</p><p><strong>Materials and methods: </strong>A total of 207 study participants were included in this retrospective case series study, where PRO data were prospectively collected for all individuals who underwent discectomy within a single metropolitan health care system between 2018 and 2023. Data on the ODI and VAS were collected at baseline and again 3 months after discectomy.</p><p><strong>Results: </strong>ODI, VAS leg pain, and VAS back pain all improved significantly from baseline to 3 months postdiscectomy. There was no correlation between age or BMI and baseline PROs ( r < 0.14).</p><p><strong>Conclusion: </strong>At 3 months postdiscectomy, there was a significant decrease in the VAS for back and leg pain as well as a significant decrease in the ODI. The anchor-based MCID for ODI differs significantly when anchored based on patient leg pain versus patient back pain. Regardless, discectomy is an effective procedure that produces clinically significant improvement in patient-reported outcomes at 3 months postprocedure with over 55% of patients meeting MCID regardless of the anchoring question.</p>","PeriodicalId":22193,"journal":{"name":"Spine","volume":" ","pages":"793-796"},"PeriodicalIF":3.5,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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