Substance Use & Misuse最新文献

{"title":"Risky Family Environment, Rumination, Drinking to Cope, and Problematic Alcohol Use: A Cross-National Examination Among College Students.","authors":"Isabela Ortiz Caso, Alanni N Brown, Rebecca J Dunaief, Adrian J Bravo, Danielle Dallaire","doi":"10.1080/10826084.2025.2562453","DOIUrl":"https://doi.org/10.1080/10826084.2025.2562453","url":null,"abstract":"<p><p><i>Objectives:</i> This study examined the relationships between risky family environments (conflictual, controlling, or aggressive parent-child [or other family members] relations), ruminative thinking, drinking to cope (DTC), and negative alcohol-related consequences among college students across seven countries (U.S., Argentina, Canada, Uruguay, Spain, South Africa, and England). Specifically, this study aimed to examine whether a risky family environment is a risk factor for problematic alcohol use <i>via</i> rumination and DTC motives among college students using a cross-national approach. <i>Method:</i> Participants (<i>n</i> = 4016; 72.7% female) were college students who consumed alcohol in the past 30 t and completed measures of risky family environment and negative alcohol-related consequences. A saturated path model (risky family environment→ruminative thinking facets→DTC→negative alcohol-related consequences) was used to test the proposed model, controlling for alcohol use quantity. Multi-group models assessed invariance of these relationships across gender and country groupings. <i>Results:</i> A significant double indirect effect was found such that greater risky family environment was associated with greater ruminative thinking (i.e., problem-focused thoughts), which in turn was associated with more DTC, which in turn was associated more negative alcohol-related consequences. Model results were invariant across gender and country groupings. <i>Conclusions:</i> Our findings emphasize the importance of addressing risky family dynamics and problem-focused thought patterns in interventions to reduce problematic alcohol use among college students. Future research is needed to establish causal relationships and explore additional factors influencing these patterns globally.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-5"},"PeriodicalIF":1.7,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of an Educational Intervention Based on the Theory of Planned Behavior on Preventing Drug Relapse Among Men with Substance Use Disorder.","authors":"Masoud Yousefi, Mohammad Ansarizadeh, Hasan Bahja, Asiyeh Yari, Amirhossein Kamyab, Ali Khani Jeihooni","doi":"10.1080/10826084.2025.2553309","DOIUrl":"https://doi.org/10.1080/10826084.2025.2553309","url":null,"abstract":"<p><strong>Background: </strong>Drug abuse has severe physical and psychological consequences, contributing to family and social instability. Given the challenges of substance use disorders, prevention is crucial. This study aimed to evaluate the effect of an educational intervention based on the Theory of Planned Behavior (TPB) on preventing drug relapse among those with substance use disorder in treatment centers in Shiraz.</p><p><strong>Methods: </strong>This experimental study included 200 drug-dependent individuals undergoing methadone and buprenorphine treatment. Participants were selected through convenience sampling and randomly assigned to intervention and control groups. Data were collected using a validated researcher-made questionnaire based on TPB and the Billings & Moos Coping Strategies Questionnaire. The intervention consisted of 14 training sessions (50-55 min each), using lectures, discussions, visual aids, and videos.</p><p><strong>Results: </strong>Before the intervention, the groups had no significant differences in knowledge, attitude, subjective norms, perceived behavioral control, or coping strategies. Six months after the intervention, the intervention group showed significant improvements in these areas compared to the control group. The relapse rate was significantly lower in the intervention group.</p><p><strong>Conclusion: </strong>The TPB-based intervention effectively improved awareness, attitude, perceived behavioral control, and coping strategies, reducing relapse rates. Implementing such educational programs in treatment centers can enhance long-term recovery outcomes.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-10"},"PeriodicalIF":1.7,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Qualitative Follow-up of the Sexual and Negative Dating Inventory (SANDI): Barriers, Facilitators, and Context of Dating and Sexual Protective Behavioral Strategies Use.","authors":"Roselyn Peterson, Elizabeth Mayer, Daniel Oesterle, Kayla Ford, Alexis Adams-Clark","doi":"10.1080/10826084.2025.2565720","DOIUrl":"https://doi.org/10.1080/10826084.2025.2565720","url":null,"abstract":"<p><strong>Background: </strong>A strong association between alcohol use and adverse sexual experiences (e.g., sexual assault, risky sex, and regretted sexual experiences) exists on college campuses in the United States. The Sexual and Negative Dating Inventory (SANDI) is a recently developed measure of dating and sexual protective behavioral strategies (PBS).</p><p><strong>Objectives: </strong>As part of the original development study, a subsample of participants (<i>n</i> = 15) was invited to participate in qualitative follow-up interviews examining contexts and environments in which they implement PBS. College students (93% female, <i>M</i>_age = 19.2, <i>SD_age</i> = 1.01, 66% heterosexual) all endorsed regular alcohol use and engagement in dating behaviors.</p><p><strong>Results: </strong>Qualitative thematic analysis of double-coded transcripts was conducted with the overarching three aims in mind: 1) to identify barriers of using dating and sexual protective behaviors, 2) to identify facilitators of using dating and sexual protective behaviors, and 3) to identify contexts in which dating and sexual protective behaviors are utilized. The following themes were identified across the three questions: 1a) trusting the other person/location, 1b) <i>awareness of and anticipation for high-risk situations</i>, 2a) d<i>ecreased reactivity and responsivity in high-risk situation</i>, 2b) not knowing the other person/location well, 3a) being in public, 3b) being in private, and 3c) depending on safety/comfort.</p><p><strong>Conclusions: </strong>Findings provide nuanced information on targeting problematic alcohol use and adverse sexual experiences among college students. Addressing barriers, facilitators, and contextual factors that influence PBS use is crucial for preventing and reducing adverse sexual experiences.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-8"},"PeriodicalIF":1.7,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145192942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bullying and Psychoactive Substance Use Among Adolescents: Evidence from a Nationally Representative Survey in Brazil.","authors":"Giuliana Perrotte, Marjorie Mastellaro Baruzzi, Julio Torales, Antonio Ventriglio, João Maurício Castaldelli-Maia","doi":"10.1080/10826084.2025.2564187","DOIUrl":"https://doi.org/10.1080/10826084.2025.2564187","url":null,"abstract":"<p><strong>Background: </strong>Bullying and the use of psychoactive substances are both prevalent among adolescents and appear to be interconnected. However, the literature has yet to reach a consensus regarding the association between being a victim of bullying and the use of psychoactive substances. In this cross-sectional study, the authors investigated the relationship between psychoactive substance use and involvement in bullying among Brazilian adolescents.</p><p><strong>Methods: </strong>Data were analyzed from the 2019 National School Health Survey (\"Pesquisa Nacional de Saúde do Escolar, PeNSE 2019\"), which included responses from 123,261 students aged 13 to 17 years. The survey assessed experiences of bullying (both as victim and perpetrator), as well as lifetime and recent (past 30 days) use of various psychoactive substances. Multivariate logistic regression models were employed to examine associations, with odds ratios (ORs) calculated to estimate the likelihood of substance use across different bullying involvement profiles.</p><p><strong>Results: </strong>Adolescents involved in bullying-whether as victims or perpetrators-had higher odds of using tobacco cigarettes, hookahs, e-cigarettes, clove cigarettes, straw cigarettes, alcohol, illicit drugs, marijuana, and crack. Those not involved in bullying had the lowest likelihood of substance use, followed by those who were only victims. The highest odds were observed among individuals who perpetrated bullying exclusively, followed by those involved as both perpetrators and victims.</p><p><strong>Conclusions: </strong>In Brazil, being a victim of bullying is associated with increased use of various psychoactive substances. These findings align with studies conducted in other Latin American countries, yet diverge in part from patterns observed in high-income countries-highlighting the influence of geographic and sociocultural contexts on these risk associations.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-9"},"PeriodicalIF":1.7,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145150850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How Widespread is the Use of E-Cigarettes Among Adults in the United States Who Have Never Smoked? A Tale of Three Studies.","authors":"Neil McKeganey, Andrea Patton, Dylan Grier, Khushneet Sandhu, Gabe Barnard","doi":"10.1080/10826084.2025.2560668","DOIUrl":"https://doi.org/10.1080/10826084.2025.2560668","url":null,"abstract":"<p><strong>Background: </strong>Whilst e-cigarettes are a less harmful means of consuming nicotine than combustible cigarettes, concerns have been expressed about their use by adults who have never smoked (ANS). It is important to quantify the prevalence of e-cigarette use and to understand patterns of use among ANS to effectively guide public health policy and regulatory decisions.</p><p><strong>Methods: </strong>The prevalence and patterns of e-cigarette use among ANS were estimated drawing upon data from three national studies in the United States; Population Assessment of Tobacco and Health Study (<i>n</i> = 29,780); the Tobacco Product Prevalence Study (<i>n</i> = 6,428); and the National Health Interview Survey (<i>n</i> = 27,651).</p><p><strong>Results: </strong>An estimated 5.0 million (5.5%) to 18.6 million (11.1%) ANS have tried e-cigarettes and most of this use is experimental. An estimated 1.5 million (1.6%) to 4.8 million (2.9%) ANS currently use e-cigarettes, and current use is primarily infrequent. However, an estimated 0.5 million (0.5%) to 2.2 million (1.3%) ANS use e-cigarettes frequently. Prevalence of e-cigarette use is highest among younger (18-24 years) ANS.</p><p><strong>Conclusions: </strong>E-cigarettes are intended to be used by adults who are currently smoking combustible cigarettes as a means of quitting combustible cigarette use or substantially reducing the number of cigarettes smoked.Therefore ANS are an unintended user population. The public health impact associated with e-cigarette use by ANS depends on whether these adults are using e-cigarettes to displace combustible cigarette use (harm avoidance) or whether they would otherwise not have initiated nicotine use if e-cigarettes were not available (harm exposure).</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-12"},"PeriodicalIF":1.7,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bidirectional Longitudinal Correlations Between Alcohol Use Frequency and Quantity, and Anxiety in Adults.","authors":"Simon D'Aquino, Benjamin Riordan, Megan Cook, Sarah Callinan","doi":"10.1080/10826084.2025.2564195","DOIUrl":"https://doi.org/10.1080/10826084.2025.2564195","url":null,"abstract":"<p><strong>Objective: </strong>Alcohol use and anxiety both contribute significantly to the global burden of disease, and understanding their longitudinal relationships may clarify whether they exacerbate each another. However, previous research on the topic has yielded mixed results, potentially due to a lack of differentiation between alcohol use patterns. This study aimed to explore the bidirectional longitudinal correlations between alcohol use frequency and quantity, and anxiety.</p><p><strong>Methods: </strong>A longitudinal random-intercept cross-lagged panel model was constructed using data from 18+ year-old individuals (<i>N</i> = 14,665), collected in the 2017 and 2019 waves of the nationally representative Household, Income, and Labor Dynamics in Australia (HILDA) survey. Anxiety was measured with the Kessler Psychological Distress Scale anxiety subscale and participants' reported frequency and quantity of alcohol use.</p><p><strong>Results: </strong>For individuals, anxiety was positively associated with subsequent alcohol use quantity, and alcohol use frequency and quantity were negatively and positively associated with subsequent anxiety, respectively. Cross-lagged effects were small in magnitude suggesting that alcohol use patterns and anxiety accounted for a small amount of change in each other.</p><p><strong>Conclusion: </strong>Results strengthen support for a reciprocal relationship between heavier alcohol use and anxiety and provide novel insight into a relationship between frequent, low quantity alcohol use, and subsequent lower anxiety. These results underscore the importance of differentiating between alcohol use patterns when evaluating mental health outcomes and emphasize that heavier drinking patterns are particularly detrimental to psychological well-being.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-7"},"PeriodicalIF":1.7,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145138834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Assessment of Marketing Strategies Used by Online Shops Selling Hemp-Derived Delta-8 Products.","authors":"Bo Huang, Emma Guess, Manasa Pragada, Clark Wilson, Geoffrey Carney-Knisely, Amy K Ferketich","doi":"10.1080/10826084.2025.2559282","DOIUrl":"https://doi.org/10.1080/10826084.2025.2559282","url":null,"abstract":"<p><strong>Introduction: </strong>Delta-8 Tetrahydrocannabinol (THC) has become increasingly popular in the United States. Many online stores sell Delta-8 THC products, yet little is known about how they are marketed to consumers.</p><p><strong>Methods: </strong>We selected a sample of popular Delta-8 online stores, captured them on one day, and coded their main pages for marketing and advertising strategies. The primary marketing strategies coded for were grouped into four main themes: 1) product claims; 2) engagement strategies; 3) user testimonials and other information; and 4) regulations and warnings. Descriptive statistics were calculated to estimate percentages of each strategy used.</p><p><strong>Results: </strong>A total of 134 online stores were identified and coded. With respect to claims, over one-third stated that a product was natural or organic (35.1%), changed energy levels (37.3%) or mood (36.5%). Engagement strategies were used by most stores, with the most common feature being a link to their social media page (79.9%) and sales and discounts on products (over 50%). Over half of websites included product reviews (60.5%) or blogs (53.7%). Nearly three-quarters (72.4%) stated that the products were not regulated by the FDA and over half (59%) required an age verification.</p><p><strong>Discussion: </strong>Surveillance is an essential public health service. For Delta-8, it is important to understand the marketing practices that retailers are using online because this setting caters to a large consumer base. Moreover, online stores can evade state regulations. A deeper investigation into Delta-8 marketing strategies could yield regulatory policies to protect public health.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-4"},"PeriodicalIF":1.7,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145131692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlates of Blunt Use Frequency and Blunt/Cigar Dual Use Among Youth and Young Adults.","authors":"Erik Crankshaw, Riley Hein, OlaOluwa Fajobi, Jennifer Lee","doi":"10.1080/10826084.2025.2548314","DOIUrl":"https://doi.org/10.1080/10826084.2025.2548314","url":null,"abstract":"<p><strong>Background: </strong>Blunts are a popular mode of cannabis use that exposes the user to nicotine and risk of nicotine addiction. We examined correlates of blunt use frequency and dual use of blunts and cigars among youth and young adults residing in New York.</p><p><strong>Methods: </strong>Data were from a survey of 15-24-year-old (<i>n</i> = 466) who reported past-year use of blunts. We used two multinomial logistic regression models with dependent variables for days of blunt use in the past 30 d and blunt and cigar, little cigar, or cigarillo (CLCC) use status in the past 30 d. Independent variables included demographic, tobacco use, and blunt-related attitude measures.</p><p><strong>Results: </strong>The study found statistically significant associations between three factors and an increased likelihood of both frequent blunt use and dual blunt/CLCC use. Specifically, the risk for both behaviors was significantly elevated among those unaware that blunt wraps contain nicotine, those with higher perceived prevalence of blunt use among their peers, and individuals reporting past-30-d use of other (non-CLCC) tobacco products. Never using flavored blunt wraps and never mixing tobacco leaf in blunts were behaviors significantly associated with lower risk of both frequent blunt use and dual blunt and CLCC use.</p><p><strong>Conclusions: </strong>Findings suggest that lack of knowledge that blunt wraps contain nicotine, adding tobacco to blunts, and the use of flavored blunt wraps are modifiable factors associated with frequent use of blunts and dual use of blunts and CLCCs.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-7"},"PeriodicalIF":1.7,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145126112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motivations and Pathways: A Thematic Analysis of Interviews with Medicinal Cannabis Consumers in Australia.","authors":"Danielle Dawson, Daniel Stjepanović, Caitlin McClure-Thomas, Valentina Lorenzetti, Wayne Hall, Tianze Sun, Janni Leung","doi":"10.1080/10826084.2025.2560074","DOIUrl":"https://doi.org/10.1080/10826084.2025.2560074","url":null,"abstract":"<p><strong>Background: </strong>Medicinal cannabis has been legally available in Australia since 2016. The current study examined the motivations for seeking medicinal cannabis and the pathways through which Australians accessed it.</p><p><strong>Methods: </strong>Brief semi-structured interviews were conducted with 15 adults who self-reported medicinal cannabis use within the past 12 months. Informants were recruited at two cannabis-related events in Queensland and New South Wales. Interviews explored motivations, pathways to access, and experiences with medicinal cannabis. Thematic analysis was conducted using Braun and Clarke's six-step framework which identified two key themes: \"<i>The Diverse Drivers of Medicinal Cannabis Use</i>\" and \"<i>Tales of Access: Journeys to Medicinal Cannabis</i>.\"</p><p><strong>Results: </strong>Informants reported varied motivations for medicinal cannabis use, including managing treatment-resistant medical conditions and avoiding the legal consequences of illicit cannabis use. Some described transitioning from recreational to medicinal use, with dual-use (i.e., both recreational and medicinal) motives described in the sample. Accessibility was reported as straightforward, through telehealth consultations and single-purpose dispensaries facilitating prescriptions. Informants reported financial barriers to accessing medicinal cannabis products and frustrations with initial prescriptions of cannabis oil rather than cannabis flower. Informants reported limited knowledge of product constituents and dosages.</p><p><strong>Conclusions: </strong>The study highlights the nuanced motivations and pathways to medicinal cannabis in Australia, including legal and medical drivers. Accessibility was described as simple through telehealth, single-purpose dispensaries but cost remained a barrier. Dual usage raises concerns about the risks associated with medicinal cannabis use. More qualitative research is needed to better understand the behaviour and risks facing medicinal cannabis consumers.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-5"},"PeriodicalIF":1.7,"publicationDate":"2025-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Impact of Loneliness on Alcohol and Cannabis Use Among College Students.","authors":"Michael Peña, Nathanael A Bierly, Ty S Schepis","doi":"10.1080/10826084.2025.2556245","DOIUrl":"https://doi.org/10.1080/10826084.2025.2556245","url":null,"abstract":"<p><p><i>Objective:</i> College students have high rates of loneliness, which impacts their quality of life and academic success. Alongside loneliness, heavy alcohol and cannabis use are common in college students, with harmful mental and physical health consequences. Loneliness and substance use are linked in studies of adults, but there are few studies of links between loneliness and substance use in college students. This study aimed to analyze links between alcohol or cannabis use and loneliness in college students, with a subfocus on differences by Greek status (i.e., social fraternity or sorority member). <i>Methods:</i> Students (<i>N</i> = 2840) were enrolled at six U.S. universities. Linear, logistic, and negative binomial regression analyses were used in the analyses, with subanalyses stratified by Greek status. <i>Results:</i> While 30-d cannabis use was not related to loneliness, 30-d alcohol use was associated with higher levels of loneliness (<i>M</i> = 43.13 ± 11.23) <i>vs.</i> nonuse (<i>M</i> = 46.57 ± 12.00). Heavier alcohol use (e.g., days of use and binge use frequency) was also linked to lower loneliness. In contrast, increasing alcohol or cannabis use consequences were linked to higher levels of loneliness. These relationships were generally consistent by Greek status, with higher levels of alcohol and cannabis use but lower levels of loneliness in Greek students (M_Greek = 41.24 ± 10.76; M_Non-Greek = 44.67 ± 11.65). <i>Conclusions:</i> College students who engage in alcohol use may have lower loneliness, but increasing consequences from alcohol or cannabis use are linked to greater loneliness. This research highlights the importance of directing intervention toward ameliorating loneliness, particularly among students with alcohol or cannabis use consequences.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-9"},"PeriodicalIF":1.7,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}