Substance Use & Misuse最新文献

{"title":"Self-Determined Motivation for Alcohol Use and Drinking Frequency, Intensity, and Consequences.","authors":"J B Courtney, M A Russell, D E Conroy","doi":"10.1080/10826084.2024.2434684","DOIUrl":"10.1080/10826084.2024.2434684","url":null,"abstract":"<p><p><i>Objective:</i> Drinking motives predict drinking behaviors and outcomes among adults. Drinking motives are rarely studied using self-determination theory (SDT), which aligns with harm-reduction approaches to alcohol use, but SDT can offer a complementary theoretical framework to existing drinking motives frameworks that may help explain the observed heterogeneity in drinking motives and account for more variance in drinking outcomes. This study examined the associations between five SDT-based drinking motives with drinking frequency, intensity, and consequences. <i>Method:</i> A total number of 630 adults (<i>M</i>_age = 21.5, 55% female, 88% undergraduates) rated drinking motives using the Comprehensive Relative Autonomy Index for Drinking (CRAI-Drinking) and the Drinking Motives Questionnaire (DMQ), typical alcohol consumption, and negative and positive drinking consequences. <i>Results:</i> Poisson regressions indicated that intrinsic (IRR = 1.13) and identified (IRR = 1.11) regulations were significantly associated with drinking frequency, identified (IRR = 0.94) and positive introjected (IRR = 1.07) regulations were significantly associated with drinking intensity, and amotivation (IRR = 1.16) and intrinsic regulation (IRR = 1.09) were associated with negative and positive consequences, respectively, after controlling for other CRAI-Drinking and DMQ scores, sex, and drinking intensity. After accounting for DMQ scores and sex, CRAI-Drinking scores accounted for 1.7%-9.9% additional deviance in drinking behaviors and consequences. <i>Conclusions:</i> Adults high in autonomous reasons for drinking reported low-risk, high-enjoyment drinking experiences. In contrast, adults with higher scores for amotivation for drinking reported more negative consequences, even after accounting for drinking intensity, suggesting that high amotivation for drinking may be a novel signal for future alcohol-related risks. These findings support the idea that SDT provides a useful framework for understanding drinking motives, behaviors, and consequences.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"787-797"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951058/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142801574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug Overdose Deaths in Mexican-Heritage Arizonans: An Examination of Mortality Rates, Demographics, Drugs Involved, and Place of Death.","authors":"Manuel Cano, Nika Hernandez, Natasha Mendoza","doi":"10.1080/10826084.2024.2447424","DOIUrl":"10.1080/10826084.2024.2447424","url":null,"abstract":"<p><strong>Objective: </strong>This study examined drug overdose deaths in Mexican-heritage Arizonans, with the goal of informing tailored overdose prevention programs for this community.</p><p><strong>Methods: </strong>We analyzed death certificate data (from the Arizona Department of Health Services) for drug overdose deaths among Arizona residents from 2018-2022. We compared deaths in US-born and foreign-born Mexican-heritage Arizonans and, as a frame of reference, Non-Hispanic (NH) White Arizonans. We compared demographics, circumstances of death, and mortality rates, using descriptive statistics, multinomial logistic regression models, and age-standardized mortality rates and ratios.</p><p><strong>Results: </strong>The age-standardized drug overdose mortality rate (per 100,000) was lower in the overall Mexican-heritage population (28.0) than in the NH White population (35.9). Nonetheless, the rate in the US-born Mexican-heritage male subgroup (59.5) was higher than in US-born NH White males (49.9) or any other subgroup examined. Synthetic opioids such as fentanyl were involved in higher proportions of deaths among US-born (64.6%) and foreign-born (65.1%) Mexican-heritage Arizonans than among NH White Arizonans (48.5%). In multinomial regression models, the risk of a medical place of death, relative to death at home, was significantly higher in the foreign-born (adjusted Relative Risk Ratio [aRRR] 1.82; 95% Confidence Interval [CI], 1.38-2.42) and US-born (aRRR 1.85; 95% CI, 1.62-2.11) Mexican-heritage groups than the NH White group, adjusting for age, sex, marital status, county of residence, overdose intent, and drugs involved.</p><p><strong>Conclusions: </strong>Findings highlight disparate rates of overdose mortality in US-born Mexican-heritage Arizona men, also underscoring racial/ethnic/nativity-based differences in overdose circumstances and decedent characteristics.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":"60 5","pages":"722-732"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification and Classification of Images in e-Cigarette-Related Content on TikTok: Unsupervised Machine Learning Image Clustering Approach.","authors":"Juhan Lee, Dhiraj Murthy, Rachel Ouellette, Tanvi Anand, Grace Kong","doi":"10.1080/10826084.2024.2447415","DOIUrl":"10.1080/10826084.2024.2447415","url":null,"abstract":"<p><strong>Background: </strong>Previous studies identified e-cigarette content on popular video and image-based social media platforms such as TikTok. While machine learning approaches have been increasingly used with text-based social media data, image-based analysis such as image-clustering has been rarely used on TikTok. Image clustering can identify underlying patterns and structures across large sets of images, enabling more streamlined distillation and analysis of visual data on TikTok. This study used image-clustering approaches to examine e-cigarette-related images on TikTok.</p><p><strong>Methods: </strong>We searched for 13 hashtags related to e-cigarettes in November 2021 (e.g., vape, vapelife). We scraped up to 1000 posts per hashtag depending on the number of available posts, for 12,599 posts in total. After randomly selecting 13% of posts and excluding non-English (<i>N</i> = 278), non-e-cigarette-related (<i>N</i> = 88), and unavailable posts (i.e., posts that the uploader deleted) (<i>N</i> = 286), <i>N</i> = 838 e-cigarette TikTok images were included in our image clustering model. Using quantitative (e.g., silhouette scores) and qualitative evaluations, we categorized clusters into overarching themes based on the types of e-cigarette content depicted within each cluster.</p><p><strong>Results: </strong>We identified <i>N</i> = 20 clusters, forming four overarching themes: (1) vapor clouds (e.g., vape tricks, vaping and exhaling vapor clouds, being captured as clouds from the mouth or nose or around the face); (2) devices (e.g., content presenting e-cigarette devices or individuals demonstrating use or modification of devices); (3) text (e.g., e-cigarette-related text inserted within images such as jokes); (4) other (i.e., e-cigarette-related images clustered based on other image characteristics such as color tones).</p><p><strong>Conclusions: </strong>This study using the state-of-the-art image-clustering method successfully identified various e-cigarette-related images on TikTok. This study suggests that novel methodologies can be helpful to tobacco regulatory agencies looking to conduct rapid surveillance of e-cigarette content on social media.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":"60 5","pages":"677-683"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11871408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143528001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Public Understanding and Perception of Harm Reduction and Prevention Messaging About Fentanyl Overdoses.","authors":"Weijia Shi, Michael Mackert, Sophia A Dove, Catherine Cunningham","doi":"10.1080/10826084.2025.2478589","DOIUrl":"10.1080/10826084.2025.2478589","url":null,"abstract":"<p><strong>Background: </strong>Fentanyl-related opioid fatalities have risen drastically in the United States, indicating a \"new wave\" of the opioid crisis and highlighting the urgent need for more effective public health interventions to address its harms. Despite an increasing number of public communication campaigns focused on the general public, evidence on how people perceive fentanyl-related harm reduction strategies and prevention messaging is still nascent.</p><p><strong>Methods: </strong>We conducted a cross-sectional survey with a national sample (<i>N</i> = 1,044). Fentanyl-related information seeking, risk perception, and message perception were measured. Specifically, message perception was compared between three harm reduction strategies-carrying naloxone, using fentanyl test strips, and never using drugs alone and between two prevention message taglines-<i>One Pill Kills</i> and <i>One Pill Can Kill</i>.</p><p><strong>Results: </strong>Respondents preferred healthcare providers and the Internet as sources if they would seek information about fentanyl. Risk perception of fentanyl was high; however, there is room to improve public awareness of naloxone as an opioid antagonist. Respondents' perception was most favorable for the message about carrying naloxone, followed by the message about using fentanyl test strips, and finally, the message about never using drugs alone. Also, <i>One Pill Can Kill</i> was associated with a higher level of perceived effectiveness than <i>One Pill Kills</i>.</p><p><strong>Conclusions: </strong>Findings indicate that harm reduction and prevention messages hold the potential to be effective in reducing the harmful consequences of fentanyl overdoses. Future research should examine whether favorable message perceptions can translate into actual effectiveness and behavioral changes, which could have implications for the development of public health interventions.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"972-977"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143650747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Demographic Characteristics and Prescription Drug Histories of Unintentional Overdose Decedents in Philadelphia, PA.","authors":"Jewell C L Johnson, Dana C Higgins, Megan Todd, Jessica M Robbins, Andrew R Best, Daniel Teixeira da Silva","doi":"10.1080/10826084.2024.2447417","DOIUrl":"10.1080/10826084.2024.2447417","url":null,"abstract":"<p><strong>Background: </strong>Philadelphia's opioid overdose crisis has reached unprecedented levels. However, overdose deaths involving non-opioids have also increased in recent years. As overdose deaths continue to increase, this study describes and compares the demographic characteristics, prescription drug histories, and exposure to potentially inappropriate prescribing practices (PIPPs), in the year before death of three groups of overdose decedents: (1) only opioid(s) detected in postmortem toxicology, (2) only non-opioid(s) detected, (3) both opioids and non-opioids co-detected [i.e. concomitant detections].</p><p><strong>Methods: </strong>Philadelphia Medical Examiner's Office data on unintentional overdose deaths from July 1, 2017 to June 30, 2022, were matched to Pennsylvania Prescription Drug Monitoring Program data. Differences were assessed using chi-square analyses, z-tests of proportions, and a multinomial logistic regression.</p><p><strong>Results: </strong>During the study period, 5,440 overdose deaths occurred in Philadelphia. Compared to the other two toxicology groups, a substantially larger proportion of non-opioid only decedents were Non-Hispanic Black (all z-tests <i>p</i>-values <0.001). In the year before death, a larger proportion of decedents with concomitant detections filled benzodiazepine and/or buprenorphine prescriptions and were exposed to PIPPs (all z-tests <i>p</i>-values <0.05). Differences by demographic characteristics, time period of death, and history of buprenorphine and benzodiazepine prescriptions remained statistically significant in the multinomial logistic regression (all <i>p</i>-values < 0.05).</p><p><strong>Conclusions: </strong>To ensure that equitable policies and prevention programs are developed, more research is needed on (1) the intersectionality of demographic characteristics and the perceived risks, preferences, and access of non-opioids (including controlled drug prescriptions), and (2) the implications of current prescribing guidelines on people who may use multiple substances.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":"60 5","pages":"684-691"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143527996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reasons for Leaving Sober Living Houses and Their Associations with Substance Use, Psychiatric, and Housing Outcomes.","authors":"Douglas L Polcin, Elizabeth Mahoney, Meenakshi Subbaraman, Amy A Mericle","doi":"10.1080/10826084.2025.2487992","DOIUrl":"10.1080/10826084.2025.2487992","url":null,"abstract":"<p><strong>Background: </strong>Sober living houses (SLHs) offer abstinence-based housing for individuals with alcohol or drug problems. Research shows residents of SLHs make improvements on measures of substance use and other problems. Length of stay (LOS) in the house is associated with outcomes. However, little is known about the reasons residents leave houses or how reasons are associated with outcomes.</p><p><strong>Methods: </strong>Baseline interviews were conducted with individuals entering 48 SLHs in Los Angeles. Residents who left within 12 months completed a 12-month follow-up interview (<i>N</i> = 352) assessing reasons they left, abstinence, psychiatric symptoms, and housing status. Multilevel regression models assessed relationships between reasons and outcomes.</p><p><strong>Results: </strong>The most commonly cited reason for leaving was wanting to live on one's own or in a shared living situation with family or friends (45.7%), which was associated with increased odds of abstinence and fewer psychiatric symptoms. Leaving due to not liking something about the house (e.g., rules or living conditions) was the second most commonly cited reason for leaving (28.1%), but was not associated with any outcomes. Wanting to live on one's own and did not get along with residents or the house manager were associated with favorable housing (i.e., stable housing or a different SLH).</p><p><strong>Conclusion: </strong>Residents who leave SLHs to live more independently in the community may be better prepared than residents who leave for other reasons. Some residents may benefit from seeking stable housing in the community or in another SLH if they are not a good match for their current house.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":"60 8","pages":"1148-1156"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12083549/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144000281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining the Relationship between Culture and Perceived Societal Substance Use Stigma in a Michigan-Based Mental Health & Addiction Focused Community.","authors":"Mayson K Whipple, Hannah Boyke, Robert C Ferrier, Pilar S Horner","doi":"10.1080/10826084.2024.2422948","DOIUrl":"10.1080/10826084.2024.2422948","url":null,"abstract":"<p><p><i>Introduction:</i> Substance use disorder (SUD) stigma undermines the implementation of effective harm reduction and treatment strategies in the U.S. and can impede individuals from seeking treatment. One research question guided this study: How do personal beliefs regarding SUD, familiarity with SUDs, and culture (religion, political ideology, and urbanicity), shape perceived societal SUD stigma? <i>Methods:</i> An online survey was sent to affiliates of a Michigan-based organization, Families Against Narcotics and administrators of Michigan Prepaid Inpatient Health Plan regional entities (<i>N</i> = 1,559). <i>Results:</i> On average respondents viewed society as moderately stigmatizing. The beliefs that drug users can stop whenever they want and that drug users have weak character were significantly associated with greater perceived levels of societal SUD stigma. The effects of religion on perceived stigma may be affected by beliefs of the immorality of drug use, while the effects of political ideology on perceived stigma may differ based on beliefs of the controllability of drug use. The effect of urbanicity may rely on perceived accessibility of treatment. <i>Conclusion:</i> Our findings reflect the intersection of personal beliefs and cultural contexts as they shape perceived societal SUD stigmatization.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"176-187"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142584381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Need Frustration and E-Cigarette Use and Dependence Among College Students: The Mediating Role of Ruminative Thinking.","authors":"Folly Folivi, Anna M Petrey, Adrian J Bravo, Laura J Holt, Alison Looby","doi":"10.1080/10826084.2024.2422951","DOIUrl":"10.1080/10826084.2024.2422951","url":null,"abstract":"<p><p><i>Background</i>: The prevalence and dependence of e-cigarettes have increased among young adult college students in recent years. Though several independent risk factors for e-cigarette use and dependence have been identified, research employing theory-informed models to predict e-cigarette use and dependence is limited. <i>Objectives</i>: Using Self Determination Theory (SDT), e-cigarette use and dependence may be understood as stemming from need frustration that impairs autonomy, competence, and relatedness, which increases vulnerability for negative health outcomes, including e-cigarette use. Further, need frustration may relate to more e-cigarette use and dependence via higher ruminative thinking, which is known to relate to both need frustration and tobacco use. <i>Method</i>: This study tested this path model (i.e., SDT need frustration components [autonomy, relatedness, competency]→rumination facets [problem-focused thoughts, counterfactual thinking, repetitive thinking, anticipatory thoughts]→e-cigarette use frequency and dependence outcomes) among 1001 college students (75.3% female; 60.4% White, non-Hispanic; 52% first-year students) who endorsed past-month e-cigarette use. <i>Results</i>: Within our path model, we found significant indirect effects via problem-focused thoughts on e-cigarette use frequency and e-cigarette dependence. Specifically, higher scores on SDT autonomy, competence, and relatedness frustration were associated with greater problem-focused thoughts, which was associated with higher e-cigarette use frequency and e-cigarette dependence scores. <i>Conclusions/Importance</i>: Results highlight the importance of distinguishing between the unique facets of rumination in understanding relations with e-cigarette use. Further intervention research targeting need frustration and ruminative thinking (particularly problem-focused thoughts) among college student e-cigarette-dependent users is needed.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"202-210"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perceived Relations Between Pain and Alcohol Use Are Associated with Hazardous Drinking Among Adults with Chronic Pain.","authors":"Lisa R LaRowe, Victoria Carl In, Joseph W Ditre","doi":"10.1080/10826084.2025.2481329","DOIUrl":"10.1080/10826084.2025.2481329","url":null,"abstract":"<p><strong>Background: </strong>Hazardous alcohol use is highly prevalent among adults with chronic pain. Although there is reason to believe that perceptions about the relationships between pain and alcohol use are important for understanding, predicting, and intervening upon alcohol use behavior, no prior work has explored such perceptions or their association with hazardous drinking.</p><p><strong>Methods: </strong>Among 273 adults who reported chronic pain and alcohol consumption (<i>M</i>_age = 33), we examined the relationship between perceptions regarding pain and alcohol use and indices of hazardous alcohol behaviors. Participants indicated the extent to which they held perceptions that (1) pain can be a motivator of alcohol consumption, (2) alcohol consumption can help one cope with pain, and (3) pain can be a barrier to quitting drinking. Alcohol use was assessed using the Alcohol Use Disorders Identification Test, which includes three indices of hazardous drinking: alcohol consumption, harmful drinking, and alcohol dependence.</p><p><strong>Results: </strong>Perceptions about pain and alcohol accounted for 16-19% of the variance in alcohol consumption, harmful drinking, and alcohol dependence (<i>p</i>s < 0.008). Specifically, perceptions that alcohol can help one cope with pain were positively associated with alcohol consumption and harmful drinking. Perceptions that pain can be a barrier to alcohol reduction were positively associated with alcohol dependence and harmful drinking.</p><p><strong>Conclusions: </strong>This is the first study to examine relationships between perceptions about pain and alcohol use and hazardous drinking. Findings contribute to a growing literature suggesting that perceptions about the interrelations between pain and substance use may contribute to hazardous patterns of use.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1236-1243"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144080330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comprehensive Cross-Sectional Analysis of Naloxone-Related Content on the Social Media Platform TikTok.","authors":"Simar Goyal, Sofia Eva Olsson, Emma DiFiore, Emma Butler, Jonah Schmitz, Cheryl Hurd","doi":"10.1080/10826084.2025.2508747","DOIUrl":"10.1080/10826084.2025.2508747","url":null,"abstract":"<p><strong>Background and objectives: </strong>There has been a surge in social media platforms being used to disseminate medical information and harm reduction techniques. Few studies have analyzed this role for the video-sharing app, TikTok, which was the most downloaded app in 2022. The present study describes the portrayal of naloxone-related content on TikTok.</p><p><strong>Methods: </strong>Specific search terms were compiled to ensure comprehensive video collection. Three trained researchers independently recorded videos using each search term and conducted independent qualitative coding analyses for the primary purpose of the content. Descriptive statistics were performed on the resulting data.</p><p><strong>Results: </strong>A total of 116 unique TikTok videos created by 77 accounts were selected for the study. Most content creators were harm reductionists (38%; <i>n</i> = 44), followed by laypersons (31%; <i>n</i> = 36). Our coding revealed that the primary purpose of the videos was either to educate audiences (80%; <i>n</i> = 93) or to advertise a product or company (16%; <i>n</i> = 18). Over half of the sample (59%; <i>n</i> = 68) physically showed a naloxone product while 31% (<i>n</i> = 36) provided insight on how to obtain naloxone.</p><p><strong>Discussion and conclusions: </strong>Naloxone-related content appears to be widely available on the social media platform TikTok. Videos were primarily created by harm reductionists seeking to educate users on the platform. With an estimated two billion users, TikTok may be an effective way to disseminate harm reduction techniques. Given the minimal education needed to administer naloxone, social media platforms such as TikTok may be useful in harm reduction education, aiding naloxone training efforts, and destigmatizing addiction and overdose treatments.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1623-1628"},"PeriodicalIF":1.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}