Substance Use & Misuse最新文献

{"title":"Age-Related Motives for Substance Use and Outcomes Among Veteran Patients Receiving Detoxification Services: A Longitudinal Study.","authors":"Erin L Woodhead, Christine Timko","doi":"10.1080/10826084.2025.2465982","DOIUrl":"https://doi.org/10.1080/10826084.2025.2465982","url":null,"abstract":"<p><strong>Objectives: </strong>Study objectives were to examine (1) baseline differences in substance use motives (social, coping, enhancement, and physical discomfort) among older, middle-aged, and younger adults, and (2) whether age group moderated associations between substance use motives at baseline and substance use outcomes at six-month follow-up.</p><p><strong>Design: </strong>Participants were assessed at baseline and followed for six months (91.1%).</p><p><strong>Setting: </strong>U.S. military veterans receiving alcohol and/or opioid detoxification services.</p><p><strong>Participants: </strong>298 participants in a study of telephone monitoring to improve detoxification outcomes.</p><p><strong>Measurements: </strong>Baseline substance use motives were measured using the Motives for Alcohol and Drug Use questionnaire. At baseline and 6-month follow-up, substance use, substance use risk, and substance use protection were measured using the Brief Addiction Monitor.</p><p><strong>Results: </strong>One-way analyses of variance with post-hoc tests found that older adults endorsed significantly lower social and coping motives for substance use than younger and middle-aged adults, and significantly lower enhancement motives than younger adults. Moderation models were analyzed using linear regression, with demographics controlled. Significant interactions of motives with age group revealed that higher endorsement of enhancement motives for substance use was associated with less protection against substance use among older adults but not among younger or middle-aged adults.</p><p><strong>Conclusions: </strong>Enhancement motives among older adults may represent a specific age-related risk for substance use. Older adults who use substances to enhance their mood and well-being may need additional resources and skills for improving mental health so that unhealthy substance use is reduced or avoided.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-9"},"PeriodicalIF":1.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Association of Risk-Related Behaviors and Mental Health Symptomatology on Problematic Alcohol Use Among U.S. Army Reserve and National Guard Soldiers.","authors":"Mehreen Arif, D Lynn Homish, Lisa D Butler, Jessica A Kulak, R Lorraine Collins, Gregory G Homish","doi":"10.1080/10826084.2025.2465967","DOIUrl":"https://doi.org/10.1080/10826084.2025.2465967","url":null,"abstract":"<p><strong>Objective: </strong>We sought to examine the association of risk behaviors (i.e., risk perception, risk-taking/impulsivity, and sensation-seeking) and mental health symptomatology (depression, posttraumatic stress disorder [PTSD], anxiety and anger) on problematic alcohol use (alcohol problems and frequent heavy drinking [FHD]) among United States Army Reserve and National Guard (USAR/NG) soldiers.</p><p><strong>Methods: </strong>Cross-sectional data (<i>N</i> = 343) from Operation: SAFETY (Soldiers And Families Excelling Through the Years), an ongoing study of USAR/NG soldiers were utilized. Negative binomial regression models investigated risk behaviors and alcohol use controlling for age and sex, with interaction models among risk behaviors and mental health symptoms.</p><p><strong>Results: </strong>Greater risk perception was associated with a lower likelihood of alcohol problems (<i>p</i> < .05), and FHD (<i>p</i> < .01). Greater risk-taking/impulsivity was associated with a greater likelihood of alcohol problems (<i>p</i> < .01). Interaction models showed moderate risk-taking/impulsivity and high sensation-seeking with depression predicted greater alcohol problems (<i>p</i> < .01, respectively). Greater sensation-seeking and PTSD symptomatology, and sensation-seeking and anxiety were associated with increased alcohol problems (<i>p</i> < .05, respectively). Moderate risk-taking/impulsivity and depression (<i>p</i> < .05), greater risk perception and greater sensation-seeking and anxiety had the highest probability of FHD (<i>p</i> < .05 and <i>p</i> < .01, respectively). No associations between risk behaviors and anger were observed.</p><p><strong>Conclusions: </strong>This study assesses the combined associations of risk behaviors and mental health on alcohol use among USAR/NG soldiers. USAR/NG soldiers may benefit from alcohol use interventions that target risk-taking/impulsivity, sensation-seeking behaviors, and mental health symptomatology such as depression, PTSD, and anxiety.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-11"},"PeriodicalIF":1.8,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143468442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"App Use and Abstinence Outcomes: The Moderating Role of Sociodemographic Variables in a Psychological Intervention to Quit Smoking.","authors":"María Barroso-Hurtado, Daniel Suárez-Castro, Carmela Martínez-Vispo, Ana López-Durán, Elisardo Becoña","doi":"10.1080/10826084.2025.2465966","DOIUrl":"https://doi.org/10.1080/10826084.2025.2465966","url":null,"abstract":"<p><strong>Background: </strong>App use is related to smoking cessation outcomes in mobile-based interventions but studies that examine its impact on traditional interventions combined with an app are still scarce. Moreover, the interplay between app use and participants' sociodemographic characteristics remains unexplored, particularly in blended smoking cessation interventions.</p><p><strong>Objectives: </strong>The study aims to explore the main effect of app use and the interactive effect of this variable and sociodemographic variables on abstinence outcomes. The sample composed of 102 participants (M_age= 44.96, SD= 9.97; 57.8% female) who received a psychological cognitive-behavioral smoking cessation intervention combined with the \"Non Fumo\" app. The Mann-Whitney U-test was used to examine differences in app use according to the smoking status at the end of the intervention, and moderation analyses were conducted to examine the interaction between app use and sociodemographic variables.</p><p><strong>Results: </strong>Results showed that abstinent participants, compared to participants who smoke, used the \"Non Fumo\" app significantly more. However, app use did not predict abstinence at the end of treatment. Regarding moderation analyses, younger participants with greater app use were more likely to achieve abstinence at the end of the treatment compared to older participants.</p><p><strong>Conclusions/importance: </strong>This study suggests that the association between app use and cessation outcomes could vary according to specific sociodemographic variables. Findings highlight the relevance of further investigating the relationship between personal characteristics and tobacco outcomes in app-based interventions. This would allow tailoring interventions according to individual characteristics to improve their effectiveness.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-7"},"PeriodicalIF":1.8,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Spatial Patterns of Delivery Hospitalizations with Opioid Use Disorder in Pennsylvania.","authors":"Jessica Frankeberger, Marian Jarlenski, Elizabeth E Krans, Robert W S Coulter, Christina Mair","doi":"10.1080/10826084.2025.2466219","DOIUrl":"10.1080/10826084.2025.2466219","url":null,"abstract":"<p><strong>Background: </strong>Opioid use disorder (OUD) in pregnancy has substantially increased throughout the drug overdose crisis, but little is known about how local community environments are associated with OUD in pregnancy. This study investigates spatial patterns and residential ZIP code-level factors associated with delivery hospitalizations with OUD in Pennsylvania and compares these patterns to those for all delivery hospitalizations and all OUD-related hospitalizations.</p><p><strong>Methods: </strong>ZIP code-level inpatient hospitalizations based on patients' residential ZIP codes in Pennsylvania were examined from 2016 to 2019. Using Bayesian hierarchical space-time conditional autoregressive models, we assessed the contributions of residential ZIP code-level factors to OUD delivery hospitalizations and compared these associations to those from models of all delivery hospitalizations and all OUD-related hospitalizations.</p><p><strong>Results: </strong>Significant spatial autocorrelation was identified for all three types of hospitalizations. Higher unemployment, greater population density, higher overall hospitalization rate, and presence of an OUD treatment facility were associated with greater OUD delivery hospitalizations in residential ZIP codes, while higher median household income and a greater proportion of the population who were non-Hispanic Black and Hispanic were associated with lower OUD delivery hospitalizations. Findings were similar to those for all OUD-related hospitalizations. The effect of ZIP code-level unemployment rate differed between all delivery hospitalizations and those with OUD, with a positive association with OUD deliveries and a negative association with all deliveries.</p><p><strong>Conclusions: </strong>Areas with worse economic conditions and greater population density are associated with OUD at delivery, similar to all OUD-related hospitalizations. Community OUD programs may consider simultaneously targeting OUD concerns in pregnancy.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-9"},"PeriodicalIF":1.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Role of Reward Functioning in the Overlap of Post-Traumatic Stress and Cocaine Use Disorder.","authors":"Kate Hull, Hanaan Bing-Canar, Krista Miloslavich, Christopher Holden, Aneet Ahluwalia, Scott D Lane, Joy M Schmitz, Margaret C Wardle","doi":"10.1080/10826084.2025.2465983","DOIUrl":"https://doi.org/10.1080/10826084.2025.2465983","url":null,"abstract":"<p><strong>Background: </strong>Posttraumatic stress disorder (PTSD) symptoms are common in people with cocaine use disorder (CUD), and even sub-threshold PSTD symptoms result in worse treatment outcomes. Difficulties with reward functioning may drive this comorbidity. Impairments in reward functioning are prominent in both PTSD and CUD and contribute to development of substance use problems after trauma. There are three distinct reward processes that may be involved in the PTSD/CUD overlap: consummatory reward (ability to experience pleasure), motivational reward (willingness to exert effort for rewards), and reward learning (adapting behavior based on reward history). Here we test whether impairments in these reward functions account for the relationship between PTSD and CUD symptoms.</p><p><strong>Methods: </strong>This is a secondary analysis of data from a clinical trial (NCT02773212) that measured of PTSD symptoms, CUD severity, consummatory reward, motivational reward, and reward learning in 53 treatment-seeking people with CUD.</p><p><strong>Results: </strong>Greater PTSD symptoms related to (1) more severe CUD and (2) less ability to learn from reward; however, impaired reward learning did not significantly account for the overlap in PTSD and CUD symptom severity.</p><p><strong>Conclusions: </strong>The observed relationship between PTSD and CUD symptoms was not accounted for by reduced ability to experience pleasure from rewards, reduced motivation for rewards, or reduced ability to learn from rewards. Thus, treatments that attempt to enhance reward functioning seem unlikely to address this complex comorbidity.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-7"},"PeriodicalIF":1.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Khat Chewing Topography: An Exploratory Study of Its Constituents and Contextual Factors.","authors":"Amanti Baru Olani","doi":"10.1080/10826084.2025.2460978","DOIUrl":"https://doi.org/10.1080/10826084.2025.2460978","url":null,"abstract":"<p><strong>Introduction: </strong>Several studies reporting the association between khat chewing and health problems emphasized the role of \"heavy use patterns.\" Such findings indicate the need to understand khat chewing topography, which is the mapping of the behavioral patterns regarding khat use and the contextual factors shaping such behaviors. The study of consumption topography offers the opportunity to examine the self-regulation systems individuals employ to maintain the desired physical and emotional state.</p><p><strong>Methods: </strong>The study relied on a qualitative method in which 102 khat chewers were recruited from the general community in Jimma, Ethiopia using snowball sampling.</p><p><strong>Results: </strong>Our findings reveal that khat chewing topography can be specified to the amount, the duration of a chewing session, the frequency, the rate, and the timing of chewing. The khat chewing topography is shaped through a complex interplay of multiple variables, which we categorized into six themes: perceived harms, the pre-chewing state, the khat variety, norms of khat chewing rate, the khat rhythm factor, and the context of chewing.</p><p><strong>Conclusion: </strong>The typical behavioral pattern that this khat chewing topography identified indicates that khat chewers are not prisoners of the psychoactive compound found in khat. Instead, they regulate their chewing behavior by considering multiple factors, including the social norms of khat consumption and the possible harm to their health, social life, and personal budget. As a result, most of the chewers were able to build a consumption topography that helped them avoid risks associated with (excessive) chewing.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-10"},"PeriodicalIF":1.8,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143450379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased Mortality Risk in Patients with Illicit Substance Use and COVID-19: Analysis of a Large Brazilian Sample.","authors":"Fabrício Emanuel Soares de Oliveira, Maria Christina L Oliveira, Daniella Reis Barbosa Martelli, Cristina Andrade Sampaio, Enrico A Colosimo, Eduardo A Oliveira, Hercílio Martelli Júnior","doi":"10.1080/10826084.2025.2465978","DOIUrl":"https://doi.org/10.1080/10826084.2025.2465978","url":null,"abstract":"<p><strong>Background: </strong>Illicit substance use (ISU) may be a potential predisposing factor for severe COVID-19 outcomes.</p><p><strong>Objective: </strong>To conduct a propensity score-matching analysis to assess and compare the mortality rate of individuals who reported ISU among a sizable cohort of hospitalized COVID-19 patients in Brazil.</p><p><strong>Methods: </strong>This population-based retrospective cohort study analyzed a nationwide Brazilian database of patients hospitalized for COVID-19. Eligible patients were aged >18 years and tested positive for SARS-CoV-2 infection. The primary exposure of interest was ISU, defined as substances prohibited under Brazilian law, primarily marijuana, cocaine, and crack. Statistical analysis was performed using t-tests, chi-square tests, the Propensity Score Matching (PSM) technique to create a balanced comparison group, and the McNemar test for paired samples to assess mortality risk among patients with ISU.</p><p><strong>Results: </strong>In a cohort of 2,124,285 patients, 1,845 had ISU. The mortality rate in the ISU group was slightly higher than that in the non-ISU group (33% vs. 32%). After PSM, we found a higher odds ratio for death in patients with ISU (OR 2.18; 95% CI 1.85-2.57; <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>Our study highlights a significant association between ISU and an increased mortality risk in COVID-19 patients.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-4"},"PeriodicalIF":1.8,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143442012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adding Nuance to Understanding the Effects of Cannabis Legalization by Using Policy Bundles: A Study of Youth Mental Health.","authors":"Shazib Altaf, Daniel J Mallinson, Mingean Park, Lilliard E Richardson","doi":"10.1080/10826084.2025.2466208","DOIUrl":"https://doi.org/10.1080/10826084.2025.2466208","url":null,"abstract":"<p><strong>Background: </strong>Variation in policy design presents a challenge for understanding the positive and negative externalities of cannabis legalization. We offer an advancement on measuring state cannabis policy variation - policy bundles - and demonstrate how the measure can be used to test the effects of cannabis legalization on youth mental health.</p><p><strong>Methods: </strong>This research employs data from the Youth Risk Behavior Survey (YRBS), released by the Centers for Disease Control and Prevention (CDC). The research focuses on utilizing three policy bundles as main exposures. This study utilizes a logistic regression model to analyze the outcome exposures. Furthermore, we employ instrumental variables to solve endogeneity between cannabis use and mental health.</p><p><strong>Results: </strong>Both the pharmaceutical and permissive policy bundle scales are associated with mental health improvements, whereas greater fiscalization has a negative impact on mental health.</p><p><strong>Conclusion: </strong>Studies of the positive and negative externalities of cannabis legalization must consider variation in policy design.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-10"},"PeriodicalIF":1.8,"publicationDate":"2025-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse Effects of Anabolic Androgenic Steroid Abuse in Athletes and Physically Active Individuals: A Systematic Review and Meta-Analysis.","authors":"Liu Mingxing, Yu Yanfei","doi":"10.1080/10826084.2025.2460986","DOIUrl":"https://doi.org/10.1080/10826084.2025.2460986","url":null,"abstract":"<p><strong>Background: </strong>Anabolic-androgenic steroids (AAS) are synthetic derivatives of testosterone, primarily used for their anabolic effects in increasing muscle mass. However, AAS have been increasingly abused, posing significant health risks due to their severe effects.</p><p><strong>Objectives: </strong>This study aimed to quantify the adverse effects of AAS abuse across a diverse population of various ages. The effects were categorized across cardiovascular, hepatic, endocrine, musculoskeletal, and psychiatric domains.</p><p><strong>Methods: </strong>A comprehensive search was conducted across multiple databases following PRISMA guidelines. Study quality was assessed using a modified QUADAS-2 tool, and meta-analyses were performed.</p><p><strong>Results: </strong>Meta-analysis revealed significant adverse outcomes. AAS use was linked to an increase in systolic blood pressure (BP) by a pooled mean difference (MD) of 12.43 mmHg (95% CI: 9.59 to 15.26) and diastolic BP by 8.09 mmHg (95% CI: 5.62 to 10.57). There was also a significant rise in LDL-C levels, with an MD of 9.12 mg/dL (95% CI: 6.75 to 11.49), indicating heightened cardiovascular risk. Hepatic effects were marked by elevated levels of AST and ALT, with MD of 14.47 U/L (95% CI: 12.41 to 16.52) and 12.16 U/L (95% CI: 3.28 to 21.04), respectively, suggesting significant liver stress or damage. Endocrine disruptions were profound, with a substantial reduction in testosterone levels observed, showing an MD of -141.57 ng/dL (95% CI: -160.42 to -122.72).</p><p><strong>Conclusions: </strong>Raising awareness among athletes and physically active people using AAS is crucial. Future research should focus on elucidating the long-term effects of AAS and developing strategies to mitigate the associated risks.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-15"},"PeriodicalIF":1.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of Retention in Oxford Houses and Other Types of Recovery Housing: A Scoping Review.","authors":"Joseph Ellis, Mira Mirzaian, Eleanor Sudduth, Maddison Ashworth, Robin Thompson, Dave Johnson, Lauren Robinson, Terry Bunn","doi":"10.1080/10826084.2024.2447935","DOIUrl":"https://doi.org/10.1080/10826084.2024.2447935","url":null,"abstract":"<p><strong>Background: </strong>Substance use disorder (SUD) is a public health crisis in the United States (U.S.), with the associated mortality rates at an all-time high. Having access to Recovery Housing (RH), and other Recovery Support Services (RSSs), supports the development of \"recovery capital\", the 'physical, social, human, and cultural resources' that can be drawn upon to initiate and help sustain long term recovery.</p><p><strong>Objectives: </strong>In this study, a scoping review of the literature was conducted to identify retention in Oxford Housing (OH) and other types of RH. Searching five databases, the search string strategy was developed to cast a broad net, using terms synonymous with \"substance use disorder\" and \"recovery housing\" to capture the highest number of relevant articles.</p><p><strong>Results: </strong>The initial search yielded 30,203 studies, with 22 studies retained and included in the final set. Overarching constructs included mental health, demographic factors, and social networks (6/22, 27.2% respectively), as well as house environment/house fit (5/22, 22.7%) and their respective impact on OH and RH retention.</p><p><strong>Conclusions: </strong>However, the individual and programmatic factors that lead to greater resident retention are not well understood. Future research efforts should be focused on further examination of these four factors, and other potential factors within the context of impacting OH and RH retention.</p>","PeriodicalId":22088,"journal":{"name":"Substance Use & Misuse","volume":" ","pages":"1-13"},"PeriodicalIF":1.8,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143392107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}