{"title":"Cardiac Computed Tomography and Echocardiography Integration for Chronic Secondary Mitral Regurgitation Quantification.","authors":"Abdulameer Jasim Jawad Al-Gburi","doi":"10.18295/2075-0528.2990","DOIUrl":"10.18295/2075-0528.2990","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to determine whether it would be possible to reclassify the severity of secondary mitral regurgitation (MR) using an integrated mitral regurgitant volume (RVol) derived from computed tomography (CT) and echocardiography data.</p><p><strong>Methods: </strong>This cross-sectional study was conducted at Ibn al-Bitar Specialized Center for Cardiac Surgery, Baghdad, Iraq. Systolic CT data of patients with isolated secondary MR were evaluated from June 2023 to December 2025. The image with the highest regurgitant orifice area (ROA) and the smallest left ventricular volume was chosen from the CT systolic phase. To calculate the integrated RVol (iRVol), the velocity time integral obtained by echocardiography was multiplied by the mitral anatomic ROA (AROA) that was obtained using planimetry.</p><p><strong>Results: </strong>A total of 113 patients were included in this study. While the mean AROA and iRVol measured by CT were 0.143 ± 0.090 cm<sup>2</sup> and 26.47 ± 10.61 mL, respectively, the mean effective ROA and RVol of MR measured by echocardiography were 0.175 ± 0.095 cm<sup>2</sup> and 27.57 ± 8.82 mL, respectively. A total of 62% of patients were reclassified from severe to non-severe MR and 21% from non-severe to severe MR when iRVol grading was used instead of only echocardiography.</p><p><strong>Conclusion: </strong>By integrating the real cross-sectional mitral ROA measured by CT with Doppler mitral haemodynamics, a quantitative metric for MR severity (called mitral iRVol) was developed, leading to a clinically important reclassification of secondary MR grade.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"26 1","pages":"355-362"},"PeriodicalIF":0.0,"publicationDate":"2026-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13188932/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147988986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparison of Efficacy of Autologous Platelet Rich Plasma Versus Silicone Products for Treatment of Scars.","authors":"Sanjay Kumar Giri, Ahana Bandyopadhyay, Santanu Suba, Sweta Singh, Bramhadatta Pattnaik, Gaurav Chhabra","doi":"10.18295/2075-0528.2987","DOIUrl":"10.18295/2075-0528.2987","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to compare the efficacy of intralesional autologous platelet rich plasma (PRP) injection in post-traumatic and post-surgical scars to a control group managed with silicone-based products. In addition, this study aimed to determine the success rate via aesthetic result, symptom improvement and outcome in terms of complications using autologous PRP on scars caused by burns or trauma.</p><p><strong>Methods: </strong>This randomised controlled trial study was conducted from August 2022 and February 2024 at the Departments of Burns and Plastic Surgery, Surgical Gastroenterology and Obstetrics and Gynaecology, AIIMS, Bhubaneswar, India. Intralesional autologous PRP injections were administered to post-traumatic or post-surgical scars of 6 weeks to 1.5 years duration. The control group was managed with silicone-based products. Clinical outcome of the scars was assessed using the Patient and Observer Scar Assessment Scale (POSAS) to determine improvement in scar characteristics and aesthetics. The Likert scale was also employed to assess the aesthetic satisfaction.</p><p><strong>Results: </strong>A total of 34 patients were included in this study (17 in each group). The PRP group reflected a statistically significant result in terms of both patient and observer factors as a part of the POSAS score. The mean observer POSAS significantly decreased from 16.76 on day 7 to 12.47 at 5 months (<i>P</i> <0.001). Mean patient POSAS also significantly decreased from 26.41 on day 7 to 19.88 at 5 months (<i>P</i> <0.001). Statistically significant improvement in Likert scale in PRP group.</p><p><strong>Conclusion: </strong>Scars following trauma or surgery showcased a significantly more efficient and faster extent of aesthetic and symptomatic improvement when treated with autologous PRP compared to silicone products.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"26 1","pages":"347-354"},"PeriodicalIF":0.0,"publicationDate":"2026-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13188934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147988995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing Estimated Premorbid IQ in Dementia in the UAE: <i>A way forward for the Gulf Cooperation Council countries</i>.","authors":"Sophie Price","doi":"10.18295/2075-0528.2988","DOIUrl":"10.18295/2075-0528.2988","url":null,"abstract":"","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"26 1","pages":"298-302"},"PeriodicalIF":0.0,"publicationDate":"2026-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13188933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147989010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ahmed Shawqi Alqattan, Ahmed Al Hashmi, Said Al Rashdi, Mohammed Al Nabhani
{"title":"Complications Following Orthognathic Surgery in Patients with Cleft Lip and/or Palate: <i>A single-centre retrospective analysis of 57 consecutive patients</i>.","authors":"Ahmed Shawqi Alqattan, Ahmed Al Hashmi, Said Al Rashdi, Mohammed Al Nabhani","doi":"10.18295/2075-0528.2986","DOIUrl":"10.18295/2075-0528.2986","url":null,"abstract":"<p><strong>Objectives: </strong>The most prevalent craniofacial abnormality in infants is cleft lip and/or palate (CL/P). Orthognathic surgery is necessary for 25-60% of patients in order to enhance face aesthetics and masticatory function. Nevertheless, there is a lack of defined complication profiles in this particular population. Thus, this study aimed to describe the spectrum and frequency of complications following orthognathic surgery in CL/P patients at a tertiary care referral centre.</p><p><strong>Methods: </strong>This retrospective cohort study included consecutive CL/P patients who underwent orthognathic surgery at Al Nahda Hospital, Muscat, Oman, between 2008-2022. Variables analysed included demographics, procedure type, length of stay and predefined complications (intraoperative haemorrhage, transfusion, dental injury, wound dehiscence, relapse, temporomandibular joint [TMJ] disorder, repeat surgery and condylar resorption). Complications were graded using the Clavien-Dindo Classification (CDC) and 95% Wilson confidence intervals (CI) were calculated.</p><p><strong>Results: </strong>A total of 57 patients were included in this study. Nearly half of patients underwent Le Fort I osteotomy (45.6%), followed by bimaxillary (31.6%), Le Fort I + genioplasty (10.5%), trimaxillary (8.8%), BSSO (1.8%) and BSSO + genioplasty (1.8%). Overall, 19 patients developed complications, most of which were CDC Grade III. The most frequent complication was relapse (10.5%), followed by TMJ disorder (5.3%), repeat surgery (5.3%), dental injury (3.5%), intraoperative haemorrhage (3.5%), wound dehiscence (1.8%), transfusion (1.8%) and there were no cases of condylar resorption.</p><p><strong>Conclusions: </strong>Complications developed in one-third of patients who underwent orthognathic surgery; however, most were manageable. Relapses were the most frequent complication and there were no life-threatening complications (CDC Grade IV-V), demonstrating overall safety of the procedure in CL/P patients.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"26 1","pages":"291-297"},"PeriodicalIF":0.0,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13178166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147964698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hepatoprotective Effect of <i>Solanum Lycopersicum</i> Extract Against High-Fat Diet-Induced Liver Injury in Rats.","authors":"Rista Dwi Hermilasari, Harry Allan Papendang","doi":"10.18295/2075-0528.2985","DOIUrl":"10.18295/2075-0528.2985","url":null,"abstract":"<p><strong>Objectives: </strong>A high-fat diet (HFD) can trigger liver disease, one of which is non-alcoholic fatty liver disease (NAFLD). This study aimed to examine the effect of <i>Solanum lycopersicum</i> extract on liver protection, namely macroscopic and microscopic aspects and liver weight in high-fat diet model rats.</p><p><strong>Methods: </strong>This true experimental study used male Wistar rats divided into a normal (control) group, HFD group and HFD group with <i>S. lycopersicum</i> extract (HFD-SL). This study was conducted from May to November 2024 at the Faculty of Dentistry Laboratory Universitas Jember, Jember, East Java, Indonesia. After the intervention, the weight of the rats' livers were measured and evaluated macroscopically. Histopathological examination was performed on liver tissue using haematoxylin and eosin staining. Steatotic and hepatocytes ballooning were analysed using scoring system.</p><p><strong>Results: </strong>A total of 21 rats were included in this study and divided equally into 3 groups. This study revealed that liver weight in the HFD group was significantly higher than in the control group (<i>P</i> = 0.004). The macroscopic findings of the liver in the HFD-SL group appeared red and the organ surface was smoother and nodules were reduced compared to the HFD group. The histopathology results of the liver in the HFD-SL group showed lower steatotic score (<i>P</i> = 0.058) and a reduced hepatocytes ballooning score (<i>P</i> = 0.018) compared to the HFD group.</p><p><strong>Conclusion: </strong><i>S. lycopersicum</i> has the potential to act as a liver protector; this occurs because the bioactive compounds in tomatoes can reduce fat accumulation and trigger hepatocyte regeneration.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"26 1","pages":"284-290"},"PeriodicalIF":0.0,"publicationDate":"2026-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13178168/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147964686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Parli Raghavan Ravi, Maha Abdullah Naseer AlShaibi, Raj Sahajanandan, Mohammed Abdullah Saif AlHosni, Srinivas Shyam Mantha
{"title":"Perioperative Outcomes and Challenges in Cytoreductive Surgery with Hyperthermic Intraperitoneal Chemotherapy: <i>A single-institution case series</i>.","authors":"Parli Raghavan Ravi, Maha Abdullah Naseer AlShaibi, Raj Sahajanandan, Mohammed Abdullah Saif AlHosni, Srinivas Shyam Mantha","doi":"10.18295/2075-0528.2984","DOIUrl":"10.18295/2075-0528.2984","url":null,"abstract":"<p><p>Cytoreductive surgery (CRS) with hyperthermic intraperitoneal chemotherapy (HIPEC) is a high-risk, but potentially curative, treatment for peritoneal surface malignancies. This retrospective analysis was conducted between March 2023 and September 2025 at Sultan Qaboos Comprehensive Cancer Care and Research Centre, Muscat, Oman, with the objective of analysing perioperative outcomes and challenges in patients undergoing CRS with HIPEC. Data on demographics, intraoperative variables and postoperative outcomes were collected and statistically analysed. A total of 25 consecutive patients were included. The cohort had significant comorbidities (American Society of Anesthesiologists II/III = 84%). Significant metabolic stress was evidenced by increased lactate (<i>P</i> <0.001) and base deficit (<i>P</i> <0.05). Haemodynamic instability necessitated frequent vasopressor use (noradrenaline = 48%). Postoperatively, 20% developed coagulopathy and 16% renal impairment. Thoracic epidural analgesia was primary in 76% of cases. Prolonged ventilation (>5 days) was needed in 12% and the mortality rate was 8% (n = 2); however, this finding should be interpreted with caution given the limited sample size. Meticulous management of haemodynamics, metabolic stress and tailored multimodal analgesia is crucial. Outcomes align with established literature, underscoring the procedure's complexity and the need for optimised protocols to enhance patient safety.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"26 1","pages":"276-283"},"PeriodicalIF":0.0,"publicationDate":"2026-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13178167/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147964712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Grand Millennium Muscat, Muscat, Oman, 5-6 February 2026.","authors":"","doi":"10.18295/2075-0528.2998","DOIUrl":"https://doi.org/10.18295/2075-0528.2998","url":null,"abstract":"","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"26 1","pages":"420-421"},"PeriodicalIF":0.0,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13431252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saleh Al Ghailani, Abdulaziz Bakathir, Ahmed Al Ajmi, Shuhra Al Washahi, Tiamour Al Baloshi, Ahmed Al Hashmi
{"title":"Complications and Outcomes of Orbital Fracture Repair in Oman.","authors":"Saleh Al Ghailani, Abdulaziz Bakathir, Ahmed Al Ajmi, Shuhra Al Washahi, Tiamour Al Baloshi, Ahmed Al Hashmi","doi":"10.18295/2075-0528.2983","DOIUrl":"10.18295/2075-0528.2983","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to investigate and analyse the complications and outcomes of orbital fracture repair in Oman.</p><p><strong>Methods: </strong>This multicentre retrospective study included all patients with orbital floor and/or medial wall fractures who underwent orbital reconstruction at four tertiary hospitals in Oman between January 2014 and December 2021. The data collected included demographics, fracture aetiology, surgical approach, reconstruction material, complications and repair outcomes.</p><p><strong>Results: </strong>A total of 41 patients were included in this study. Motor vehicle collisions (MVCs) were the most common cause of orbital fractures, accounting for (53.7%) of the patients. Isolated orbital fractures were encountered in 25 patients, 12 patients had orbital fractures associated with the zygomaticomaxillary complex and 4 had fractures associated with naso-orbital ethmoidal fractures. The transconjunctival approach was the most common surgical method (36.6%), followed by the infraorbital approach (24.4%). Titanium mesh was the primary implant material used in (63.4%) of the cases. The most common complications at 2-weeks to 3-months postoperatively were enophthalmos (17.1%) and residual diplopia (13%). Beyond 3 months postoperatively, complications occurred in 10 patients, resulting in an overall complication rate of (24.4%). Analysis of 24 postoperative computed tomography scans revealed that the ideal implant positioning in the anterior, middle and posterior zones was achieved in (87.5%), (45.8%) and (12.5%) of the cases, respectively.</p><p><strong>Conclusion: </strong>The study findings showed that MVCs were the primary cause of orbital fractures in Oman. The complication rate of orbital reconstruction was low and comparable to that reported in the published literature.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"26 1","pages":"266-275"},"PeriodicalIF":0.0,"publicationDate":"2026-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13037667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147594198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anwar Al Shuaili, Huda Kashoob, Zahida Niaz, Nausheen Yaqoob, Khadhra Ahmed J Galaal, Reem Ahmed Al Mazrouai
{"title":"Primary Vaginal Epithelioid Haemangioendothelioma with Pulmonary Metastasis: <i>A case report and review of the literature</i>.","authors":"Anwar Al Shuaili, Huda Kashoob, Zahida Niaz, Nausheen Yaqoob, Khadhra Ahmed J Galaal, Reem Ahmed Al Mazrouai","doi":"10.18295/2075-0528.2982","DOIUrl":"10.18295/2075-0528.2982","url":null,"abstract":"<p><p>Epithelioid haemangioendothelioma (EHE) is a rare vascular sarcoma of intermediate malignancy. In 2023, a 31-year-old female presented to a tertiary care hospital in Muscat, Oman, with symptoms later diagnosed as primary vaginal EHE. The patient had primary, locally invasive vaginal EHE that subsequently metastasised to the lungs. The patient experienced progression of systemic disease despite chemotherapy and was therefore transitioned to palliative chemotherapy. The clinical, radiological and histopathological findings as well as the diagnostic features that distinguish EHE from its aggressive mimic, epithelioid angiosarcoma, are described in this report. This case highlights the diagnostic challenges, the importance of molecular confirmation and the unpredictable clinical course of this ultra-rare malignancy. To the best of the authors' knowledge, this is the first reported case of primary vaginal EHE.</p>","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"26 1","pages":"259-265"},"PeriodicalIF":0.0,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13037670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147594683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}