Sultan Qaboos University Medical Journal最新文献_第2页

Epidemiology, Risk Factors and Clinical Outcome of Candidaemia: A decade-long experience at a university hospital in Oman. 念珠菌血症的流行病学、危险因素和临床结果：阿曼一所大学医院长达十年的经验。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/2075-0528.2832

Tasneem Al Salmani, Asmaa S Mahdi, Abdullah Balkhair, Turkiya Al Siyabi, Hashim Ba Wazir

{"title":"Epidemiology, Risk Factors and Clinical Outcome of Candidaemia: A decade-long experience at a university hospital in Oman.","authors":"Tasneem Al Salmani, Asmaa S Mahdi, Abdullah Balkhair, Turkiya Al Siyabi, Hashim Ba Wazir","doi":"10.18295/2075-0528.2832","DOIUrl":"10.18295/2075-0528.2832","url":null,"abstract":"Objectives: This study aimed to examine a decade-long epidemiology of candidaemia to explore the risk factors associated with it, and describe its clinical outcomes in hospitalised adult patients.Methods: This retrospective observational study was conducted at Sultan Qaboos University Hospital, Muscat, Oman. Adult patients with candidaemia hospitalised between January 2007 and December 2016 were included. The hospital infection control department surveillance registry on bloodstream infections (BSIs) was used to identify Candida BSIs. Patients' electronic medical records were searched for demographic characteristics, clinical risk factors and outcomes.Results: Candida albicans was the most common Candida species among 152 patients with candidaemia comprising 25.0% of all Candida blood culture isolates. Nakaseomyces glabrata, C. tropicalis and C. parapsilosis were the most frequently isolated non-albicans species. Past antibiotics use, presence of central venous catheters, intensive care unit admission, diabetes mellitus, sickle cell disease and solid cancer were the most commonly identified underlying risk factors for candidaemia. A total of 30 days' all-cause mortality was 53.3% among all patients with candidaemia.Conclusions: This study found an increasing trend of non-albicans Candida. Diabetes was the most identified risk factor for candidaemia. A relatively low rate of initiation of empirical antifungal therapy in at-risk patients was found. Unacceptably high mortality rates and prolonged hospital stay of patients with candidaemia are a call for action.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"233-241"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12240031/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anomalous Origin of the Posterior Descending Artery Causing Inferolateral Myocardial Ischaemia in an Octogenarian. 一位八旬老人后降支异常起源引起外侧心肌缺血。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/squmj.10.2024.062

Ahmad R Bagheri, Madan M Maddali, Adil A Al-Jabri

引用次数: 0

Diagnostic Accuracy of Abdominal Ultrasonographic Sliding Sign in the Evaluation of Severe Intra-Abdominal Adhesions Involving the Uterus in Women Undergoing Repeat Caesarean Delivery: Systematic review and meta-analysis. 腹部超声滑动征在评估重复剖宫产妇女严重腹内粘连累及子宫中的诊断准确性：系统回顾和荟萃分析。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/squmj.10.2024.063

Amira M Taha, Wesam A Moawad, Sara A A Saed, Tala J Alhejazi, Youstina A Sabri, Mohamed Abd-ElGawad, Juan L Alcazar, Nihal Al Riyami, Ayatallah Khafagy, Yasmine A Mohammed, Ahmed H Saad

{"title":"Diagnostic Accuracy of Abdominal Ultrasonographic Sliding Sign in the Evaluation of Severe Intra-Abdominal Adhesions Involving the Uterus in Women Undergoing Repeat Caesarean Delivery: Systematic review and meta-analysis.","authors":"Amira M Taha, Wesam A Moawad, Sara A A Saed, Tala J Alhejazi, Youstina A Sabri, Mohamed Abd-ElGawad, Juan L Alcazar, Nihal Al Riyami, Ayatallah Khafagy, Yasmine A Mohammed, Ahmed H Saad","doi":"10.18295/squmj.10.2024.063","DOIUrl":"10.18295/squmj.10.2024.063","url":null,"abstract":"This review aimed to assess diagnostic accuracy of transabdominal ultrasonography (TAS) sliding sign in diagnosing severe intra-abdominal adhesions with repeated Caesarean delivery (CD). PubMed, Google Scholar, Web of Science and Scopus were searched for published studies until October 2022. Studies evaluating the sliding sign as a predictor of intra-abdominal adhesions after repeat CD were included. STATA and Comprehensive Meta-Analysis for meta-analysis was used. A total of 7 studies (1,318 patients) were included. For identifying severe intra-abdominal adhesions, sliding sign on TAS had a combined sensitivity (64%, 95% confidence interval [CI]: 55-71%), specificity (93%, 95% CI: 89-96%), positive likelihood ratio (9.5, 95% CI: 5.7-16), negative likelihood ratio (0.39, 95% CI: 0.31-0.49) and diagnostic odds ratio (24, 95% CI: 13-46). Prediction intervals for sensitivity and specificity were 0.444-0.786 and 0.711-0.985, respectively. Sliding sign on TAS is a simple, non-invasive, good negative and practical method to exclude severe intra-abdominal adhesions involving the uterus with low sensitivity and high specificity.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"29-37"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12244295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144609569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characteristics and Outcomes of Cancer Patients Admitted to the Hospital With Community- Acquired Pneumonia. 社区获得性肺炎住院癌症患者的特点和结局。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/squmj.10.2024.058

Anoud Al-Saleh, Dana Hassouneh, Sara Dhaydel, Nour Faqeer

{"title":"Characteristics and Outcomes of Cancer Patients Admitted to the Hospital With Community- Acquired Pneumonia.","authors":"Anoud Al-Saleh, Dana Hassouneh, Sara Dhaydel, Nour Faqeer","doi":"10.18295/squmj.10.2024.058","DOIUrl":"10.18295/squmj.10.2024.058","url":null,"abstract":"Objectives: Community-acquired pneumonia (CAP) poses a significant risk of complications in cancer patients. However, limited studies have evaluated hospitalised cancer patients with CAP. This study aimed to evaluate the characteristics and outcomes of cancer patients hospitalised with CAP.Methods: This retrospective study included adult cancer patients diagnosed with CAP admitted at the King Hussein Cancer Center, Jordan, from January 2021 to August 2022, following the Infectious Diseases Society of America guidelines. Patient characteristics, microbiological cultures, length of hospital stay, intensive care unit (ICU) transfers and all-cause mortality were recorded. Early clinical stability was defined as temperature ≤37.8°C, heart rate ≤100 beats/min, respiratory rate ≤24 breathes/min, systolic blood pressure ≥90 mmHg and oxygen saturation ≥90% while breathing room air on the third day of admission.Results: A total of 632 cancer patients were admitted with CAP. The mean age was 60 ± 13.9 years, with 55.2% of the patients being male. Breast cancer was the most prevalent malignancy (22.9%), and 48.6% had received cancer-related treatment within the last 2 months. Positive blood and sputum cultures were detected in 12.4% and 30.0% of patients, respectively. Early clinical stability was achieved in 48.9%, and 88.9% of those patients were discharged after a median stay of 6 days (range: 1-48). Among the included patients, 3.2% required ICU transfer, and 10.9% died.Conclusions: Early clinical stability was achieved in approximately half of the patients, most of whom were discharged home. Future research should identify interventions to improve clinical outcomes for cancer patients with CAP.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"83-90"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12255339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Empagliflozin Use in Cardiac Transplant Patients: Real-world experience from Saudi Arabia. 恩帕列净在心脏移植患者中的应用：来自沙特阿拉伯的真实世界经验。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/squmj.10.2024.057

Muhammad I Butt, Roaa M H Albalwi, Norah Alnassar, Reem Alghamdi

{"title":"Empagliflozin Use in Cardiac Transplant Patients: Real-world experience from Saudi Arabia.","authors":"Muhammad I Butt, Roaa M H Albalwi, Norah Alnassar, Reem Alghamdi","doi":"10.18295/squmj.10.2024.057","DOIUrl":"10.18295/squmj.10.2024.057","url":null,"abstract":"Objectives: Sodium-glucose transport protein 2 (SGLT2) inhibitors are used in the treatment of patients with type 2 diabetes. Besides their beneficial metabolic effects, such as lowering glycated haemoglobin, body weight and blood pressure, these agents have shown favourable and protective effects on both the heart and kidneys. Notably, these cardio-renal benefits are even seen in individuals without diabetes. However, there is limited evidence regarding the safety and efficacy of SGLT2 inhibitors in cardiac transplant recipients. This study aimed to assess the safety and efficacy of empagliflozin in cardiac transplant recipients with diabetes.Methods: This retrospective study was conducted at the King Faisal Specialist Hospital & Research Centre in Riyadh, Saudi Arabia, from June 2003 to May 2024. Patients from the cardiac transplant recipient register who were taking empagliflozin or a combination of empagliflozin and metformin were included. Consequently, their safety and efficacy parameters were examined.Results: A total of 20 patients were included in this study. There was an improvement in haemoglobin A1C (HbA1C) levels, body weight and stability in serum creatinine. Additionally, there was no increased risk of genitourinary infections, hypoglycaemia or diabetic ketoacidosis.Conclusions: Although larger studies are needed to examine the use of empagliflozin in cardiac transplant patients, this small study provides assurance that empagliflozin is safe for use in cardiac transplant recipients.","PeriodicalId":22083,"journal":{"name":"Sultan Qaboos University Medical Journal","volume":"25 1","pages":"91-97"},"PeriodicalIF":0.0,"publicationDate":"2025-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12255340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unusual Presentation of Osteoid Osteoma with Exacerbating Pain during Menses. 骨样骨瘤的不寻常表现并在月经期间加剧疼痛。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 eCollection Date: 2025-01-01 DOI: 10.18295/squmj.10.2024.067

Wassan Nori, Shaymaa K Abdulqader, Nabeeha N Akram, Raid M Al-Ani, Qays A Hassan, Alexandru C Pantazi

引用次数: 0

Disconnected Pancreatic Duct Syndrome in Complicated Necrotising Pancreatitis. 并发坏死性胰腺炎的胰管断开综合征。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/2075-0528.2825

Nasiba Al Maqrashi, Noor Al Wahaibi, Salim Al Busaidi, Abdullah Al Alawi

引用次数: 0

Endobronchial Metastasis with Extension to the Left Atrium from Adenocarcinoma of Gastric 3 Years after Total Gastrectomy. 全胃切除术后3年胃腺癌支气管内转移并向左心房转移。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/squmj.10.2024.066

Behnam Shakerian, Mohammad H Mandegar

引用次数: 0

Bullous Diabeticorum.

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/2075-0528.2860

Maisam Alsalmani, Ayida Al Khalili, Maiya Al Bahri

引用次数: 0

Pneumocephalus After Mediastinal Surgery. 纵隔手术后的脑气。

Sultan Qaboos University Medical Journal Pub Date : 2025-05-02 DOI: 10.18295/2075-0528.2854

Mohamed Bhairis, Massine El Hammoumi, El Hassane Kabiri

引用次数: 0