Spinal cord最新文献

{"title":"Patient flow problems affecting in-patient spinal cord injury rehabilitation in the Netherlands.","authors":"Linda M M van der Schriek, Marcel W M Post, Catja A Dijkstra, Peter W New, Janneke M Stolwijk-Swüste","doi":"10.1038/s41393-024-01058-6","DOIUrl":"10.1038/s41393-024-01058-6","url":null,"abstract":"<p><strong>Study design: </strong>Prospective cohort study.</p><p><strong>Objectives: </strong>To describe barriers to admission to and discharge from an inpatient rehabilitation unit for patients with newly acquired spinal cord injury or disease (SCI/D) and to identify modifiable factors whereby patient flow can be optimized.</p><p><strong>Setting: </strong>Netherlands.</p><p><strong>Methods: </strong>In-patients with newly acquired SCI/D referred to a rehabilitation centre in the Netherlands between December 2018 and December 2019 were included. Demographic, clinical characteristics and information about waiting days and causes of delay were recorded. Descriptive analysis was used.</p><p><strong>Results: </strong>In total, 105 patients were included; 33 patients (31%) were female, mean age was 59 years, 60% had a non-traumatic SCI/D, 42% of the SCI/D were tetraplegia and 62% were AIS D at referral. No significant differences in demographic or clinical characteristics were found between patients with and without a barrier to admission. Most common admission barriers were bed availability and capacity of nursing and other health staff. The most frequent discharge barriers were delay in care approval, lack of availability of nursing home places and waiting for home modifications.</p><p><strong>Conclusion: </strong>Most frequent admission barriers were availability of beds and staffing capacity; most discharge barriers were problems with home modifications, waiting for care approval or a nursing home place. Recommendations for reducing these barriers are recognizing a potential problem at an early stage, timely communication with patient and/or family about options for discharge, while simultaneously initiating a home modification plan and exploring temporary accommodation options.</p>","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":" ","pages":"201-207"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143042263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Histology of neurogenic heterotopic ossification and comparison with its radiological expression in acute spinal cord injured patients.","authors":"Eugen Ulrich, Alexis Brinkemper, Manfred Köller, Ingo Stricker, Astrid Gisevius, Thomas A Schildhauer, Renate Meindl, Dennis Grasmücke, Sabrina Buche-Lyding, Volkmar Nicolas, Mirko Aach","doi":"10.1038/s41393-025-01070-4","DOIUrl":"10.1038/s41393-025-01070-4","url":null,"abstract":"<p><strong>Study design: </strong>Clinical prospective study.</p><p><strong>Objectives: </strong>To histologically examine puncture biopsies of early neurogenic heterotopic ossification (NHO) in spinal cord injured individuals.</p><p><strong>Setting: </strong>University of Bochum, Germany.</p><p><strong>Methods: </strong>After acute spinal trauma, participants underwent a sonographic examination of the hip joints and a routine laboratory examination. Magnetic resonance imaging (MRI) or computed tomography (CT) of the pelvis was performed if there were clinical and laboratory signs of NHO and sonographic evidence of edema and/or calcifications in the tissue around the hip joint. If NHO were detected, tissue was obtained and preserved for histological examination from the involved tissue around the hip joint affected by NHO and from an unaffected calf as control. Nine participants with a complete spinal cord lesion American Spinal Injury Association Impairment Scale (AIS) grade A and evidence of an acute NHO in the hip joint muscles were recruited for the study.</p><p><strong>Results: </strong>In all sonographic examinations of the hip joint, edematous changes could be detected. In one case, calcifications were detected sonographically. In MRI/CT in six participants, ossification could already be detected. All histological specimens from the NHO-affected gluteal region showed varying degrees of tissue deformation. The unaffected reference samples showed regular muscular structure microscopically.</p><p><strong>Conclusions: </strong>It was possible to show and compare histological changes in NHO-affected tissue with MRI/CT imaging, depending on the stage of NHO.</p><p><strong>Trial registration: </strong>DRKS, DRKS00034049. Registered 12 April 2024 - Retrospectively registered, https://www.drks.de/DRKS00034049 .</p>","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":" ","pages":"227-232"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12003164/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of a new model of care for bladder management in a statewide spinal cord service.","authors":"Belinda J Gabbe, Stacey Rj Haughton, Andrew Nunn, Marnie Graco, Chris Michael, Sandra Reeder, Rebekah McGaw, David J Berlowitz","doi":"10.1038/s41393-024-01059-5","DOIUrl":"10.1038/s41393-024-01059-5","url":null,"abstract":"<p><strong>Study design: </strong>Registry-based cohort study.</p><p><strong>Objectives: </strong>To evaluate the impact of the introduction of a new bladder management model of care at the Victorian Spinal Cord Service (VSCS) on the incidence of subsequent emergency department presentations and readmissions to hospital for urinary tract infection (UTI) in the first 2 years after injury.</p><p><strong>Setting: </strong>VSCS, Austin Health, Melbourne, Australia.</p><p><strong>Methods: </strong>A new model of care that prioritized intermittent self-catheterization was implemented at the VSCS on 1 August 2017. Data from the Victorian State Trauma Registry and Austin Health medical record were used to compare the rate of readmissions, emergency department (ED) presentations and hospitalisations for UTI in the first two years post-injury before and after practice was changed.</p><p><strong>Results: </strong>A total of 333 cases were included; 149 cases pre-model of care change and 184 cases after. 143 males and 41 females with a mean (SD) age of 48.9 (19.7) were admitted to the VSCS following the change in model of care. The rate of any subsequent hospitalisation for UTI (ED presentation or admission) was lower following the introduction of the new bladder management model of care (Incidence rate ratio 0.30, 95% CI 0.12-0.73).</p><p><strong>Conclusions: </strong>Our data demonstrates the real-world impact of a change in bladder management after new SCI. These data strengthen the consensus recommendation in current practice guidelines.</p>","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":" ","pages":"189-193"},"PeriodicalIF":2.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12003175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143011938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatments of fatigue after spinal cord injury: a systematic review and meta-analysis","authors":"Carlos Leonardo Cano-Herrera,&nbsp;Gita Manhas,&nbsp;Matthew Querée,&nbsp;Bob Hoogenes,&nbsp;Emma A. Bateman,&nbsp;Eldon Loh,&nbsp;William C. Miller,&nbsp;W. Ben Mortenson,&nbsp;Andrea Townson,&nbsp;Janice J. Eng,&nbsp;the SCIRE Research Team","doi":"10.1038/s41393-025-01067-z","DOIUrl":"10.1038/s41393-025-01067-z","url":null,"abstract":"Systematic Review and Meta-analysis. Canada. Fatigue is one of the most common consequences of spinal cord injury (SCI). In this systematic review and meta-analysis, we examined interventions for fatigue in SCI and evaluated their effectiveness. MEDLINE, EMBASE, CINAHL, and PsycINFO databases were searched up to January 2024 inclusive. Randomized controlled trials (RCTs) that assessed any intervention for at least one fatigue outcome in people with SCI were included. Study quality was assessed using the Cochrane Risk of Bias Tool. Initial screening identified 282 studies from which six RCTs were included in the review (N = 249). One study found that moderate-intensity arm-crank exercise significantly improved fatigue compared to a control group (p = 0.036) with a large effect size (standard mean difference [SMD] = 1.05; 95% confidence interval [CI], 0.10–2.00). Two studies assessing behavioral interventions found a moderate effect on fatigue (SMD = 0.46; 95% CI, −0.00–0.92; p = 0.05). Two studies did not find an effect of massage therapy on fatigue (SMD = 0.06; 95% CI, −0.38–0.50; p = 0.80). The risk of bias was classified as High for all but two of the RCTs. These findings suggest that exercise and behavioral interventions promoting an active lifestyle may have a positive effect on fatigue. More research with larger sample sizes, including controls for co-morbid conditions like pain and depression, is needed to establish evidence-based treatments for reducing fatigue in people with SCI.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"63 3","pages":"149-158"},"PeriodicalIF":2.1,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mindfulness- and acceptance-based interventions for people with spinal cord injury: a scoping review","authors":"Mengqi Li,&nbsp;Wing Yiu Lo,&nbsp;Yule Hu,&nbsp;Shanshan Wang,&nbsp;Tsz-Ching Sun,&nbsp;Worku Animaw Temesgen,&nbsp;Mengting He,&nbsp;Yan Li","doi":"10.1038/s41393-025-01068-y","DOIUrl":"10.1038/s41393-025-01068-y","url":null,"abstract":"Scoping review. To synthesize the effects of mindfulness- and acceptance-based interventions (MABIs) on health-related outcomes of individuals with spinal cord injury. The included studies were conducted across four countries: The United States, Iran, China, and The United Kingdom. This review followed the Arksey and O’Malley framework and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews guideline. Seven databases were searched until November 2024 to identify studies published in English-language that evaluated MABIs’ effects on health-related outcomes in people with spinal cord injury. Literature screening, data extraction, and quality assessment were conducted by two reviewers independently. A narrative data synthesis was conducted. Of 2389 records, nine studies were included with designs of randomized controlled trials (n = 4), quasi-experimental studies (n = 3), and case studies (n = 2). Acceptance commitment therapy (n = 4) and mindfulness-based interventions (n = 5) were employed. MABIs demonstrated significant improvements in psychological health outcomes (depression, n = 3; anxiety, n = 3; stress, n = 2) with medium-to-large effect sizes ( $${{{{rm{eta }}}}}_{{{{rm{p}}}}}^{2}=0.112-0.223$$ ) and other health-related outcomes (chronic pain, n = 1; functional independence, n = 1; engagement in meaningful activities, n = 1; and quality of life, n = 1). Participants found the MABIs to be acceptable and satisfactory. Study quality varied from weak (n = 6) to strong (n = 2). The findings generally support the acceptability and effectiveness of MABIs for improving the overall well-being of individuals with SCI. Future research directions regarding designing MABIs and exploring effectiveness mechanisms were recommended for maximizing its benefits.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"63 3","pages":"159-170"},"PeriodicalIF":2.1,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical signs and symptoms for degenerative cervical myelopathy: a scoping review of case-control studies to facilitate early diagnosis among healthcare professionals with stakeholder engagement","authors":"Suhani Sharma,&nbsp;Alisha Sial,&nbsp;Stone Sima,&nbsp;Ashish Diwan","doi":"10.1038/s41393-025-01065-1","DOIUrl":"10.1038/s41393-025-01065-1","url":null,"abstract":"Scoping Review. Degenerative cervical myelopathy (DCM) is a leading cause of chronic spinal cord dysfunction, with diverse clinical presentations that complicate diagnosis. Therefore, it is important to identify the signs and symptoms of DCM that demonstrate high diagnostic accuracy. This review aims to evaluate the sensitivity and specificity of signs and symptoms in diagnosing DCM. Articles up to June 2024 were retrieved from PubMed, EMBASE, and Cochrane databases using search terms like “degenerative cervical myelopathy”, “cervical spondylotic myelopathy”, “sensitivity”, “specificity”, and related signs and symptoms. Studies were screened based on selection criteria assessing the sensitivity and specificity of signs or symptoms using an appropriate control group. Sixteen studies were included. The most sensitive signs were Tromner sign (93–97%) and hyperreflexia (15–85%). Specific signs included the Babinski sign (93–100%), Tromner sign (79–100%), clonus (96–99%), and inverted supinator sign (78–99%). Neck pain had a sensitivity of 76–94% and specificity of 11–73%. Hand incoordination showed 52% sensitivity and 92% specificity. Altered hand sensation had 76% sensitivity and 90% specificity. Upper extremity weakness had 51–75% sensitivity and 18–95% specificity. Gait imbalance exhibited 56–63% sensitivity and 52–95% specificity. Sensitive signs like the Tromner sign and hyperreflexia are useful for screening, while specific signs such as Babinski, clonus, and the inverted supinator sign aid in confirmation of DCM. Symptoms like neck pain, hand incoordination, and altered hand sensation should heighten suspicion and guide differential diagnosis. Early and accurate diagnosis using these indicators can improve patient outcomes and reduce diagnostic delays.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"63 3","pages":"171-180"},"PeriodicalIF":2.1,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41393-025-01065-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of melatonin administration on motor recovery after spinal cord injury in animal models: a systematic review and meta-analysis","authors":"Ali Khodabakhshi Korelaei,&nbsp;Arash Fallahi,&nbsp;Michael R. Hamblin,&nbsp;Fatemeh Ramezani","doi":"10.1038/s41393-025-01063-3","DOIUrl":"10.1038/s41393-025-01063-3","url":null,"abstract":"Systematic review and meta-analysis. In this study, the effects of the antioxidant melatonin on motor function after spinal cord injury were investigated in preclinical studies. IRAN The search strategy was designed based on keywords related to melatonin and spinal cord injury. The primary screening was based on title and abstract, and the secondary screening was based on the full text of the articles. After extracting data from the articles, statistical analysis was performed using STATA software. Standardized mean differences were used to analyze the results of the included studies. Subgroup analysis and quality control of articles were also performed. Based on the results of 29 separate experiments, melatonin showed a significant strong effect compared to the untreated group. The results showed that IP injection and multiple administrations days had the strong effect in the first three days as well as after 3–4 weeks. But more studies are needed to draw conclusions about its longer term effects. The analysis of MDA, SOD and GSH redox factors showed that the amount of MDA decreased and the amount of GSH increased in the treated animals. Also, the inflammatory factors IL-1Β and TNF-α as well as apoptosis and the rate of neuronal cell death, were reduced in animals that received melatonin, while the number of viable neurons was increased in melatonin treated animals. Melatonin is an antioxidant supplement, which can be considered for clinical trials in human SCI patients. IRAN University of medical sciences","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"63 3","pages":"135-148"},"PeriodicalIF":2.1,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143469337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nerve transfers to anterior interosseous nerve for restoration of finger flexion in spinal cord and brachial plexus injury: a systematic Review and individual-patient-data meta-analysis","authors":"Pavlos Texakalidis,&nbsp;Stavros Matsoukas,&nbsp;Nikhil Murthy,&nbsp;Adenike A. Adewuyi,&nbsp;Nader S. Dahdaleh,&nbsp;Colin K. Franz,&nbsp;Kevin Swong","doi":"10.1038/s41393-025-01066-0","DOIUrl":"10.1038/s41393-025-01066-0","url":null,"abstract":"Systematic review and meta-analysis. Cervical spinal cord injury (SCI) and brachial plexus injury (BPI) can result in hand paralysis. Reconstruction of hand motion is associated with improved functionality and quality of life. We synthesized the outcomes of finger and thumb flexion after various nerve transfers to the anterior interosseous nerve (AIN). A systematic literature review and meta-analysis was performed according to the PRISMA guidelines. Successful finger and thumb flexion recovery was defined as Medical research council (MRC) grade ≥3. In total, 23 studies with 99 patients and 120 nerve transfers to the AIN were performed. The mean interval from injury to surgery was 12.8 months and mean follow-up duration was 24 months. Overall, 81/120 (67.5%) and 68/102 (66.7%) hands achieved successful finger and thumb flexion recovery, respectively. Individual-patient-data were available for 94 nerve transfers. Type of injury (SCI vs BPI/peripheral) did not affect finger flexion outcomes (OR 1.92, 95%CI 0.74–5.0, p = 0.17). On multivariate analysis adjusted for mechanism of injury, timing of injury to surgery and duration of follow-up, utilization of the brachioradialis (BR) branch (25%, 1/4, OR 0.01, 95%CI 0.0006–0.44, p = 0.01) and brachialis (BA) branch (59%, 30/51, OR 0.06, 95%CI 0.006–0.68, p = 0.02) as donors, were associated with statistically significant lower odds of successful finger flexion recovery compared to extensor carpi radialis brevis (ECRB) use (95%, 19/20). Similar outcomes were observed with SCI and BPI/peripheral type injuries. ECRB utilization as a donor was superior to BA or BR branch in terms of successful finger flexion recovery.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"63 3","pages":"127-134"},"PeriodicalIF":2.1,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143441990","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The potential role of RhoA/ROCK-inhibition on locomotor recovery after spinal cord injury: a systematic review of in-vivo studies","authors":"Armin Khavandegar,&nbsp;Negar Sadat Ahmadi,&nbsp;Maryam Alsadat Mousavi,&nbsp;Zahra Ramezani,&nbsp;Elaheh Khodadoust,&nbsp;Mahgol Sadat Hasan Zadeh Tabatabaei,&nbsp;Zahra Hasanpour Segherlou,&nbsp;Arman Zeinaddini-Meymand,&nbsp;Fatemeh Nasehi,&nbsp;Maral Moafi,&nbsp;Kimia RayatSanati,&nbsp;Rasool Masoomi,&nbsp;Sorour Hamidi,&nbsp;Soheila Pourkhodadad,&nbsp;Vafa Rahimi-Movaghar","doi":"10.1038/s41393-025-01064-2","DOIUrl":"10.1038/s41393-025-01064-2","url":null,"abstract":"Systematic Review. To thoroughly assess the existing literature regarding the impact of anti-RhoA/ROCK agents or procedures on functional recovery in animal models of SCI. Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences. A comprehensive search was conducted in Ovid MEDLINE, Embase, Scopus, and Web of Science Core Collection utilizing a combination of keywords. All in-vivo animal studies of acute or chronic SCI that evaluated the pharmacological effects of Rho/ROCK inhibitors in English literature were included in this study. Totally, 2320 articles were identified, of which, 60 papers were included for further analysis. A total of 47 (78%) studies were conducted merely on rats, 9 (15%) on mice, 3 (5%) used both, and the remaining used other animals. Y-27632, Fasudil, C3 Transferase and its derivatives (C3-05/PEP-C3/CT04/C3bot154–182/C3bot26mer(156–181)), Ibuprofen, Electroacupuncture (EA), SiRhoA, miR-133b, miR-135-5p, miR-381, miR-30b, Statins, 17β-estradiol, β-elemene, Lentivirus-mediated PGC-1a, Repulsive guidance molecule (RGMa), Local profound hypothermia, Jisuikang (JSK), Hyperbaric oxygen (HBO), Lv-shRhoA (Notch-1 inhibitor), Anti-Ryk antibody, LINGO-antagonist, BA-210, p21Cip1/WAF1, ORL-1 antagonist, Epigallocatechin‐3‐gallate (EGCG), Tamsulosin, AAV.ULK1.DN, and Indomethacin were the 28 reported agents/procedures with anti-RhoA/ROCK effects. The pooled SMD for BBB scores was 0.41 (p = 0.048) in the first week, 0.85 (p &lt; 0.001) in the second week, 1.22 (p = 0.010) in the third week, and 1.53 (p = 0.001) in the fourth week. Of the 28 identified anti-RhoA/ROCK agents, all but two (C3bot and its derivatives and EGCG) demonstrated promising results. The results of the meta-analysis cautiously indicate a significant increase in BBB scores over time after SCI.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"63 3","pages":"95-126"},"PeriodicalIF":2.1,"publicationDate":"2025-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Retraction Note: Prevalence of prescribed opioid claims among persons with nontraumatic spinal cord dysfunction in Ontario, Canada: a population-based retrospective cohort study","authors":"Qi Guan,&nbsp;Mary-Ellen Hogan,&nbsp;Andrew Calzavara,&nbsp;Daniel McCormack,&nbsp;Aisha K. Lofters,&nbsp;Tejal Patel,&nbsp;Sander L. Hitzig,&nbsp;Tanya Packer,&nbsp;Sara J. T. Guilcher","doi":"10.1038/s41393-025-01061-5","DOIUrl":"10.1038/s41393-025-01061-5","url":null,"abstract":"","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"63 3","pages":"1-1"},"PeriodicalIF":2.1,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41393-025-01061-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143123622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}