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Reliability of the Mini-BESTest and Brief-BESTest for assessing patients with incomplete spinal cord injury 用于评估不完全脊髓损伤患者的迷你测试(Mini-BESTest)和简短测试(Brief-BESTest)的可靠性
IF 2.1 4区 医学
Spinal cord Pub Date : 2024-09-13 DOI: 10.1038/s41393-024-01032-2
Yusuke Morooka, Yasuyuki Takakura, Yosuke Kunisawa, Yuya Okubo, Shinta Araki, Shigeru Obayashi
{"title":"Reliability of the Mini-BESTest and Brief-BESTest for assessing patients with incomplete spinal cord injury","authors":"Yusuke Morooka, Yasuyuki Takakura, Yosuke Kunisawa, Yuya Okubo, Shinta Araki, Shigeru Obayashi","doi":"10.1038/s41393-024-01032-2","DOIUrl":"10.1038/s41393-024-01032-2","url":null,"abstract":"Single institution observational study. To investigate the ceiling and floor effects of the Berg Balance Scale (BBS), Mini-Balance Evaluation Systems Test (BESTest), and Brief-BESTest, as well as to determine the intra- and inter-rater reliabilities and minimal detectable change (MDC) of the Mini-BESTest and Brief-BESTest in patients with acute and subacute incomplete cervical spinal cord injury (SCI) classified as AIS D. Advanced critical care center of our university hospital. Twenty patients with incomplete cervical SCI who could stand without assistance were recruited. The floor and ceiling effects were evaluated by plotting histograms from the distribution of scores on the BBS, Mini-BESTest and Brief-BESTest, and calculating skewness. The Mini-BESTest and Brief-BESTest were evaluated and videotaped simultaneously, and intra- and inter-rater reliabilities were assessed. The MDC was also calculated. The skewness of the BBS was −1.57, and the full score was 35%, indicating a ceiling effect. However, no ceiling or floor effect was observed for the Mini-BESTest and the Brief-BESTest. Intraclass correlation coefficients for intra-rater and inter-rater reliabilities were 0.98 and 0.97 for the Mini-BESTest and Brief-BESTest, respectively. Individual item reliability was moderate or better for the Mini-BESTest and excellent or better for the Brief-BESTest. The MDC of total scores ranged 3.14–3.84 and 2.92–3.60 for the Mini-BESTest and Brief-BESTest, respectively. The Mini-BESTest and Brief-BESTest are reliable assessment tools for patients with acute and subacute incomplete SCI classified as AIS D. Clarified error ranges aid in estimating the treatment effect on balance abilities.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 12","pages":"676-682"},"PeriodicalIF":2.1,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142227708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A home-based self-directed EEG neurofeedback intervention for people with chronic neuropathic pain following spinal cord injury (the StoPain Trial): description of the intervention 针对脊髓损伤后慢性神经性疼痛患者的家庭自主脑电图神经反馈干预(StoPain 试验):干预说明
IF 2.1 4区 医学
Spinal cord Pub Date : 2024-09-12 DOI: 10.1038/s41393-024-01031-3
Negin Hesam-Shariati, Lara Alexander, Kevin Yi Chen, Ashley Craig, Paul A. Glare, Mark P. Jensen, Chin-Teng Lin, James H. McAuley, James W. Middleton, G. Lorimer Moseley, Toby Newton-John, Sebastian Restrepo, Ian W. Skinner, Pauline Zahara, Sylvia M. Gustin
{"title":"A home-based self-directed EEG neurofeedback intervention for people with chronic neuropathic pain following spinal cord injury (the StoPain Trial): description of the intervention","authors":"Negin Hesam-Shariati, Lara Alexander, Kevin Yi Chen, Ashley Craig, Paul A. Glare, Mark P. Jensen, Chin-Teng Lin, James H. McAuley, James W. Middleton, G. Lorimer Moseley, Toby Newton-John, Sebastian Restrepo, Ian W. Skinner, Pauline Zahara, Sylvia M. Gustin","doi":"10.1038/s41393-024-01031-3","DOIUrl":"10.1038/s41393-024-01031-3","url":null,"abstract":"Randomised controlled trial. The objective is to describe an electroencephalography (EEG) neurofeedback intervention that will be provided in a randomised controlled trial for people with neuropathic pain following spinal cord injury (SCI): the StoPain Trial. In this trial, participants in the treatment group will implement an EEG neurofeedback system as an analgesic intervention at home, while participants in the control group will continue with the treatments available to them in the community. University-based study in Sydney, Australia. This manuscript describes the rationale and components of the EEG neurofeedback intervention designed for individuals with SCI neuropathic pain and intended for home-based implementation. Our report is based on the criteria of the Template for Intervention Description and Replication (TIDieR) checklist, and includes why the efficacy of EEG neurofeedback will be investigated, what will be provided, who will administer it, and how, where, when, and how much the EEG neurofeedback intervention will be administered. This manuscript provides a detailed description of a complex intervention used in a randomised controlled trial. This description will facilitate the subsequent interpretation of the trial results and allow for the replication of the intervention in clinical practice and future trials. Australian Government Medical Research Future Fund (2020 Rare Cancers Rare Diseases and Unmet Needs Scheme: 2006020).","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 11","pages":"658-666"},"PeriodicalIF":2.1,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41393-024-01031-3.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of wheelchair skills training during peer-led Active Rehabilitation Camps for people with spinal cord injury in Poland: a cohort study 波兰脊髓损伤患者在同伴引导的积极康复营期间接受轮椅技能培训的效果:一项队列研究
IF 2.1 4区 医学
Spinal cord Pub Date : 2024-09-11 DOI: 10.1038/s41393-024-01034-0
Tomasz Tasiemski, Piotr Kazimierz Urbański, Sophie Jörgensen, Dawid Feder, Katarzyna Trok, Anestis Divanoglou
{"title":"Effects of wheelchair skills training during peer-led Active Rehabilitation Camps for people with spinal cord injury in Poland: a cohort study","authors":"Tomasz Tasiemski, Piotr Kazimierz Urbański, Sophie Jörgensen, Dawid Feder, Katarzyna Trok, Anestis Divanoglou","doi":"10.1038/s41393-024-01034-0","DOIUrl":"10.1038/s41393-024-01034-0","url":null,"abstract":"Prospective cohort study. To evaluate the effects of wheelchair skills training (WSTR) for participants with spinal cord injury (SCI) during peer-led Active Rehabilitation Camps (ARC) in Poland. We hypothesized that participation in ARC will improve wheelchair skill performance and self-efficacy in individuals with SCI. We also aimed to determine demographic and injury-related factors associated with greater improvements in wheelchair skill performance and self-efficacy. Thirteen consecutive ARCs in Poland. Participants (n = 122) with traumatic or nontraumatic SCI older than 16 years were evaluated at the beginning (T1) and completion (T2) of ARC and at 3-month follow-up (T3) through the Queensland Evaluation of Wheelchair Skills (QEWS) and the Wheelchair Skills Test Questionnaire (WST-Q). At T2, 43% of participants reached the threshold for substantial clinically meaningful change in QEWS, 73% in WST-Q capacity, and 67% in confidence, with approximately half of those reporting such gains at T3. At a group level, participants achieved small effect-size improvements (QEWS) at T2; large effects in wheelchair skills capacity at T2 and T3; large effects in wheelchair skill confidence at T2, and low effects at T3. Prior attendance to ARC was the only independent variable that explained 10% of variance in wheelchair capacity gains. Peer-led WSTR during ARCs is highly effective at improving wheelchair skills in individuals with SCI. These improvements are largely retained after three months. Persons with SCI should have a chance to participate in more than one camp to maintain and further improve their wheelchair skills.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 11","pages":"651-657"},"PeriodicalIF":2.1,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142224181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Traumatic spinal cord injury and its correlation to risk of autoimmune/-inflammatory disease 创伤性脊髓损伤及其与自身免疫性/炎症性疾病风险的相关性
IF 2.1 4区 医学
Spinal cord Pub Date : 2024-09-11 DOI: 10.1038/s41393-024-01026-0
Tim Damgaard Nielsen, Thomas Munk Laursen, Bodil Hammer Bech, Mikkel Mylius Rasmussen
{"title":"Traumatic spinal cord injury and its correlation to risk of autoimmune/-inflammatory disease","authors":"Tim Damgaard Nielsen, Thomas Munk Laursen, Bodil Hammer Bech, Mikkel Mylius Rasmussen","doi":"10.1038/s41393-024-01026-0","DOIUrl":"10.1038/s41393-024-01026-0","url":null,"abstract":"Nationwide epidemiological open cohort study. To evaluate whether individuals with traumatic spinal cord injury (TSCI) are more prone to develop autoimmune diseases compared to a general non-TSCI population. Danish public national registries. An open nationwide cohort, including individuals born in Denmark from or alive during 1945-2018 was collected and the study period was 1980-2018. Poissons Log-linear regression estimated the incidence rate ratio (IRR) for developing eight groups of autoimmune diseases. A dose-response relationship based on the cervical/thoracic level of injury was assessed by stratification. The cohort included 3,272 individuals with TSCI and 4.8 million background individuals, accounting for 50,865 and 140 million person-years respectively. The TSCI population had an overall IRR of 1.81 (95% CI, 1.59 to 2.05) of getting any autoimmune disease. Subgroup analysis found positive associations for; a) Other neurologic IRR 5.19 (95% CI, 2.79 to 9.65), b) multiple sclerosis IRR 3.70 (95% CI, 2.54 to 5.40), c) Dermatologic IRR 2.57 (95% CI, 1.86 to 3.55), d) Type 1 diabetes mellitus IRR 2.01 (95% CI, 1.54 to 2.61), e) Systemic 1.92 (95% CI, 1.44 to 2.55), and f) Gastroenterologic IRR 1.42 (95% CI, 1.05 to 1.92). Cervical levels of TSCI showed an IRR of 1.70 (95% CI, 1.43 to 2.02), while thoracic levels had an IRR 1.98 (95% CI, 1.63 to 2.39). TSCI may be an individual risk factor of developing an autoimmune disease. There does not appear to exist a dose-response relationship from the level of injury. None.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 11","pages":"642-650"},"PeriodicalIF":2.1,"publicationDate":"2024-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41393-024-01026-0.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bibliometric analysis of research on spinal cord and sacral neuromodulation in spinal cord injury 有关脊髓损伤中脊髓和骶神经调节研究的文献计量分析
IF 2.1 4区 医学
Spinal cord Pub Date : 2024-09-09 DOI: 10.1038/s41393-024-01029-x
Jishi Ye, Jingli Chen, Juan Wang, Juan Ren, Yifan Jia, Zhongyuan Xia
{"title":"Bibliometric analysis of research on spinal cord and sacral neuromodulation in spinal cord injury","authors":"Jishi Ye, Jingli Chen, Juan Wang, Juan Ren, Yifan Jia, Zhongyuan Xia","doi":"10.1038/s41393-024-01029-x","DOIUrl":"10.1038/s41393-024-01029-x","url":null,"abstract":"Qualitative studies. Spinal cord injury (SCI) is one of the most devastating injuries to the central nervous system that places a major burden on society. Neuromodulation technology involving spinal cord stimulation (SCS) and sacral nerve modulation (SNM) is a promising technique for patients with SCI. However, there has been no bibliometric analysis of research in this field to date. Not applicable. Systematic analyses of countries, institutions, authors, journals, co-cited documents, keywords, genes and diseases were performed. Related gene and disease data from the citexs platform were also reviewed. A total of 7437 articles on SCS and SNM in SCI were retrieved from the Web of Science database. The search time was limited to 1985-01-01 to 2022-12-31. We identified a significant increase in research output on SCS and SNM in SCI in recent years, with a concentrated period of high publication activity. Multiple publications were identified on neuropathic pain, electronic stimulation, TNF, BDNF and STAT3 gene expression, indicating that complications and potential therapeutic strategies for SCI are a key focus in the field. Our study provides insights that may help to advance scientific research and potentially improve outcomes in patients with SCI.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 11","pages":"634-641"},"PeriodicalIF":2.1,"publicationDate":"2024-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142185270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Does the presence of preoperative neck pain impact clinical outcomes after posterior decompression in patients with cervical ossification of the posterior longitudinal ligament?: Retrospective multicenter cohort study 颈椎后纵韧带骨化症患者术前颈部疼痛是否会影响后路减压术后的临床效果?
IF 2.1 4区 医学
Spinal cord Pub Date : 2024-09-05 DOI: 10.1038/s41393-024-01027-z
Toshiki Okubo, Narihito Nagoshi, Takahito Iga, Takashi Tsuji, Yosuke Horiuchi, Kazuya Kitamura, Kenshi Daimon, Haruki Funao, Kazuki Takeda, Masahiro Ozaki, Satoshi Suzuki, Osahiko Tsuji, Morio Matsumoto, Masaya Nakamura, Kota Watanabe, Ken Ishii, Junichi Yamane
{"title":"Does the presence of preoperative neck pain impact clinical outcomes after posterior decompression in patients with cervical ossification of the posterior longitudinal ligament?: Retrospective multicenter cohort study","authors":"Toshiki Okubo, Narihito Nagoshi, Takahito Iga, Takashi Tsuji, Yosuke Horiuchi, Kazuya Kitamura, Kenshi Daimon, Haruki Funao, Kazuki Takeda, Masahiro Ozaki, Satoshi Suzuki, Osahiko Tsuji, Morio Matsumoto, Masaya Nakamura, Kota Watanabe, Ken Ishii, Junichi Yamane","doi":"10.1038/s41393-024-01027-z","DOIUrl":"10.1038/s41393-024-01027-z","url":null,"abstract":"Retrospective multicenter study. To evaluate how preoperative neck pain influences clinical outcomes following posterior decompression for cervical ossification of the posterior longitudinal ligament (OPLL). Fourteen medical institutions in Japan. We enrolled 90 patients with cervical OPLL who underwent posterior decompression and were followed for a minimum of two years. We collected demographic data, medical history, and imaging findings. Patients were divided into two groups based on preoperative neck pain presence (Pre-op. neck pain (−) and (+) groups), and their outcomes were compared. There were no significant differences in patient demographics between the Pre-op. neck pain (−) and (+) groups. Both groups showed similar distributions of ossification types and K-line positivity. Perioperative complications were comparable between the two groups. Radiographic analysis revealed no significant differences in C2–7 angles or cervical range of motion, pre- and postoperatively. Both groups demonstrated significant improvement in postoperative Japanese orthopedic association (JOA) scores, but there were no significant differences in scores or recovery rates. In the Pre-op. neck pain (−) group, factors associated with appearance of postoperative neck pain included pre- and postoperative lower JOA scores and larger C2–7 angles in neutral and extension positions. It emerges that lower pre- and postoperative JOA scores or larger C2–7 angles in neutral and extension positions predispose to postoperative neck pain even in those patients without preoperative neck pain. Therefore, this is worth discussing at the time of consenting patients for surgical decompression and fixation.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 11","pages":"619-624"},"PeriodicalIF":2.1,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence, causes, and risk profile of rehospitalizations in persons with spinal cord injury within the first 10 years after primary rehabilitation 脊髓损伤患者在初级康复后头 10 年内再次住院的发生率、原因和风险概况。
IF 2.1 4区 医学
Spinal cord Pub Date : 2024-09-05 DOI: 10.1038/s41393-024-01028-y
Inge E. Eriks-Hoogland, Lea Studer, Lorena L. Müller, Benjamin Hirsch, Jürgen Pannek, Armin Gemperli, Cristina Ehrmann
{"title":"Prevalence, causes, and risk profile of rehospitalizations in persons with spinal cord injury within the first 10 years after primary rehabilitation","authors":"Inge E. Eriks-Hoogland, Lea Studer, Lorena L. Müller, Benjamin Hirsch, Jürgen Pannek, Armin Gemperli, Cristina Ehrmann","doi":"10.1038/s41393-024-01028-y","DOIUrl":"10.1038/s41393-024-01028-y","url":null,"abstract":"Retrospective cohort study. This study aims to identify the prevalence, causes, time pattern and risk profile of rehospitalizations in persons with spinal cord injury (SCI) within a 10-year period following primary rehabilitation and identify most common secondary health conditions (SHCs) and risk profile leading to rehospitalizations. Specialized hospital and rehabilitation center for SCI in Switzerland. A retrospective analysis was conducted on clinical data from persons with SCI, discharged from initial rehabilitation between January 1, 2010, and December 31, 2012, and followed up over a period of ten years post-discharge. Descriptive statistical methods were utilized to compute the rehospitalization prevalence and to identify the primary reasons. 225 participants were included, 70% were male (n = 179), and the mean age was 50 years (SD 19, Range 17–88). 54% were classified as having paraplegia (n = 122), and 77% incomplete injuries (n = 180). Over the 10-year observation period post-discharge, 120 were readmitted at least once, (prevalence 53%). In total, 66 persons (29%) were rehospitalized once or twice, while 54 persons (24%) were rehospitalized three or more times, with a maximum of 14 times. In the 10-year period, the most common SHCs leading to rehospitalization were infections (19%), pressure injuries (18%), and gastrointestinal problems (16%). During the study period, 57 persons (25%) passed away. Rehospitalization after primary rehabilitation is frequent and in the majority of the cases due to SHCs. The study findings are valuable for resource planning in healthcare and can guide the implementation of preventive measures to avoid SHCs.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 11","pages":"625-633"},"PeriodicalIF":2.1,"publicationDate":"2024-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142141103","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of exercise on autonomic cardiovascular control in individuals with chronic, motor-complete spinal cord injury: an exploratory randomised clinical trial 运动对慢性完全性运动性脊髓损伤患者自律性心血管控制的影响:一项探索性随机临床试验。
IF 2.1 4区 医学
Spinal cord Pub Date : 2024-08-31 DOI: 10.1038/s41393-024-01019-z
Tristan W. Dorey, Tom E. Nightingale, Abdullah A. Alrashidi, Stefan Thomas, Katharine D. Currie, Michèle Hubli, Shane J. T. Balthazaar, Andrei V. Krassioukov
{"title":"Effects of exercise on autonomic cardiovascular control in individuals with chronic, motor-complete spinal cord injury: an exploratory randomised clinical trial","authors":"Tristan W. Dorey, Tom E. Nightingale, Abdullah A. Alrashidi, Stefan Thomas, Katharine D. Currie, Michèle Hubli, Shane J. T. Balthazaar, Andrei V. Krassioukov","doi":"10.1038/s41393-024-01019-z","DOIUrl":"10.1038/s41393-024-01019-z","url":null,"abstract":"Secondary analysis of a clinical trial. To assess the impact of 6 months of arm cycle ergometry training (ACET), or body weight-supported treadmill training (BWSTT), on autonomic cardiovascular responses to a laboratory sit-up test (SUT) in individuals with chronic (≥1-year post-injury) spinal cord injury (SCI). Tertiary Rehabilitation Centre, Vancouver, Canada. Sixteen individuals with motor-complete (American Spinal Injury Association Impairment Scale A-B) SCI between the fourth cervical and sixth thoracic spinal cord segments, aged 39 ± 11 years, were assessed. Participants were randomized to receive 72 sessions of moderate-to-vigorous intensity ACET (n = 8) or passive BWSTT (n = 8). Changes in mean arterial pressure (finger plethysmography), hemodynamics (Modelflow® method), and heart rate/heart rate variability (HR/HRV; electrocardiography) were measured in response to a  SUT before and after 6 months of exercise training. Spontaneous cardiovagal baroreflex sensitivity (cvBRS) was assessed using the sequence method. Neither ACET nor BWSTT impacted hemodynamic responses to SUT or the incidence of orthostatic hypotension (all P > 0.36). ACET increased HR (P < 0.01, ηp2 = 0.34) and high frequency (HF) power HRV responses (P < 0.01, ηp2 = 0.42) to SUT following 6 months of training while BWSTT did not. Consistent with this, cvBRS improved (P < 0.05, ηp2 = 0.16) only following ACET. Improvements in cvBRS were correlated with both the HR (r = 0.726, P < 0.0001) and HF power (r = −0.484, P < 0.01) responses to SUT. Six months of ACET, but not BWSTT, improved cardiovagal baroreflex control of HR but had no effect on BP responses to SUT in individuals with chronic, motor-complete SCI. Canadian Institutes of Health Research (CIHR) NCT01718977","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 10","pages":"597-604"},"PeriodicalIF":2.1,"publicationDate":"2024-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142112159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
White matter spinal tracts impairment in patients with degenerative cervical myelopathy evaluated with the magnetization transfer saturation MRI technique 利用磁化转移饱和磁共振成像技术评估退行性颈椎病患者的脊髓白质束损伤情况。
IF 2.1 4区 医学
Spinal cord Pub Date : 2024-08-28 DOI: 10.1038/s41393-024-01025-1
Elena Filimonova, Mars Abdaev, Ivan Vasilenko, Yulij Kubetskij, Oleg Prokhorov, Jamil Rzaev
{"title":"White matter spinal tracts impairment in patients with degenerative cervical myelopathy evaluated with the magnetization transfer saturation MRI technique","authors":"Elena Filimonova, Mars Abdaev, Ivan Vasilenko, Yulij Kubetskij, Oleg Prokhorov, Jamil Rzaev","doi":"10.1038/s41393-024-01025-1","DOIUrl":"10.1038/s41393-024-01025-1","url":null,"abstract":"Prospective case-control study. We investigated the use of the magnetization transfer saturation (MTsat) technique to assess the structural integrity of the spinal cord tracts in individuals with clinically significant degenerative cervical myelopathy (DCM) and associated disability. Novosibirsk Neurosurgery Centre, Russia. A total of 53 individuals diagnosed with DCM and 41 patients with cervical radiculopathy underwent high-resolution MRI of the cervical spinal cord via the magnetization transfer technique. The MRI data were processed using the Spinal Cord Toolbox (v5.5), with MTsat values determined for each spinal tract and compared between the two groups. Furthermore, associations between MTsat values and the clinical disability rates of patients were investigated. A significant decrease in the MTsat of the ventral spinocerebellar tract was observed in the DCM group compared to the control group (adjusted p < 0.001). There was a trend towards lower MTsat values in the rubrospinal tract in the DCM group (adjusted p = 0.08). Additionally, a decrease in MTsat values in the lateral funiculi of the spinal cord was found in patients with DCM (adjusted p < 0.01). Furthermore, a trend toward a positive correlation was observed between the JOA score and the MTsat values within the ventral spinocerebellar tract (R = 0.33, adjusted p = 0.051). The findings of our study indicate that demyelination in patients with DCM affects mainly the ventral spinocerebellar and rubrospinal tracts, and the extent of changes in the ventral spinocerebellar tract is related to the severity of the condition.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 10","pages":"590-596"},"PeriodicalIF":2.1,"publicationDate":"2024-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s41393-024-01025-1.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142081544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychological screening of significant others during spinal cord injury rehabilitation 脊髓损伤康复期间重要他人的心理筛查。
IF 2.1 4区 医学
Spinal cord Pub Date : 2024-08-27 DOI: 10.1038/s41393-024-01024-2
Tijn van Diemen, Eline W. M. Scholten, Nelleke G. Langerak, Ilse J. W. van Nes
{"title":"Psychological screening of significant others during spinal cord injury rehabilitation","authors":"Tijn van Diemen, Eline W. M. Scholten, Nelleke G. Langerak, Ilse J. W. van Nes","doi":"10.1038/s41393-024-01024-2","DOIUrl":"10.1038/s41393-024-01024-2","url":null,"abstract":"Retrospective cohort study. Determine the course of burden and psychological distress of significant others (SOs) during initial spinal cord injury (SCI) rehabilitation and to predict the caregiver’s burden at discharge with characteristics of SOs and persons with SCI (PSCIs) at the start of rehabilitation. Rehabilitation center Sint Maartenskliniek, Nijmegen, The Netherlands. All PSCIs admitted for initial rehabilitation between October 2020 and December 2022 were included. One of their SOs were asked to complete a set of screening questionnaires, collected in our routine context of care. A total of 181 PSCIs (62% male, average age 60 years, 80% incomplete SCI, 60% paraplegia and 32 days after injury) and 158 SOs (40% male, average age 57 years) were screened at admission, and 145 and 93 at discharge, respectively. For SOs, the average caregiver’s burden and feelings of depression and anxiety did not change during admission. The caregiver’s burden score at discharge was best predicted by the burden score at admission, explaining 20% (P < 0.001) of the variance. An additional 13% (P = 0.02) of the variance was explained by other SO and PSCI variables gathered in this study. The caregiver’s burden in this group of SOs during rehabilitation, was higher than that of a representative group in the chronic phase. On both assessments, around 20% scored above the cutoff. Scores of psychological distress are comparable to former studies. Standard screening of SOs during initial SCI rehabilitation is important to help the interdisciplinary team identify SOs at risk, and target their treatment during inpatient rehabilitation.","PeriodicalId":21976,"journal":{"name":"Spinal cord","volume":"62 10","pages":"584-589"},"PeriodicalIF":2.1,"publicationDate":"2024-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142081543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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