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Current Research on Laser Use in Oncology最新文献

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Analytical simulation of thermal processes under laser light interaction with multilayered biological tissue 激光与多层生物组织相互作用下热过程的分析模拟
Current Research on Laser Use in Oncology Pub Date : 2005-08-08 DOI: 10.1117/12.640141
V. Barun, A. P. Ivanov
{"title":"Analytical simulation of thermal processes under laser light interaction with multilayered biological tissue","authors":"V. Barun, A. P. Ivanov","doi":"10.1117/12.640141","DOIUrl":"https://doi.org/10.1117/12.640141","url":null,"abstract":"An analytical procedure to study linear thermal processes in multilayered biological tissues irradiated by a laser beam is proposed. The procedure is based on the simplified representation of the heat source function after the irradiation. The Green function of both temporal and radial coordinates of the thermal problem is analytically derived in the paper. It enables one to easy simulate spatial and temporal temperature distributions in tissue by a simple convolution. Pulsed or continuous-wave laser beams with any radial structures can be treated. The validity of the approximations assumed to get the Green function is verified by comparing the simulations with published data on both light and thermal fields in tissues. Rather a good agreement is shown. Specific attention is paid to the most critical approximation, namely to the separation of radial and depth coordinates in the thermal source function. The applicability of such an approach is discussed and quantitatively checked by evaluating the temporal dynamics of radial light and heat spot spreading. The procedure is used to study thermal processes in irradiated skin layers under wide variations of optical parameters of the problem. Sample results on the heating effects of a sensitizer used for photodynamic therapy are illustrated.","PeriodicalId":219206,"journal":{"name":"Current Research on Laser Use in Oncology","volume":"52 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129273101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Method of autofluorescence diagnostics for detecting premorbid conditions of inflammatory periodontium tissue diseases 检测炎症性牙周组织疾病发病前状况的自体荧光诊断方法
Current Research on Laser Use in Oncology Pub Date : 2005-08-08 DOI: 10.1117/12.640226
M. Sinyaeva, N. Kozlova, A. Mamedov, A. Berezin, S. Vasilchenko, A. I. Volkova, V. Loschenov
{"title":"Method of autofluorescence diagnostics for detecting premorbid conditions of inflammatory periodontium tissue diseases","authors":"M. Sinyaeva, N. Kozlova, A. Mamedov, A. Berezin, S. Vasilchenko, A. I. Volkova, V. Loschenov","doi":"10.1117/12.640226","DOIUrl":"https://doi.org/10.1117/12.640226","url":null,"abstract":"During the last several years researches have been carried out in order to study the possibility of autofluorescence diagnostics application in dentistry for caries and different periodontium tissues diseases diagnostics. We carried out the research of periodontium tissues autofluorescence images and spectra to develop the method of autofluorescence diagnostics of premorbid conditions of inflammatory periodontium tissues diseases.","PeriodicalId":219206,"journal":{"name":"Current Research on Laser Use in Oncology","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131617889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Factors determining the photocatalytic activity of immobilized porphyrins in organic and water media 固定化卟啉在有机和水介质中光催化活性的影响因素
Current Research on Laser Use in Oncology Pub Date : 2005-08-08 DOI: 10.1117/12.640131
V. Belyaev, A. Solovieva, N. Glagolev, G. Vstovsky, S. Timashev, A. Krivandin, O. Shatalova, V. N. Luzgina
{"title":"Factors determining the photocatalytic activity of immobilized porphyrins in organic and water media","authors":"V. Belyaev, A. Solovieva, N. Glagolev, G. Vstovsky, S. Timashev, A. Krivandin, O. Shatalova, V. N. Luzgina","doi":"10.1117/12.640131","DOIUrl":"https://doi.org/10.1117/12.640131","url":null,"abstract":"The kinetic parameters of the cholesterol (in water) and tryptophane (in organic solvents) photooxidation sensitized by aminoacid derivatives of tetraphenylporphyrin immobilized on MF-4SK sulfocationic copolymer (analogue of N afion 117) were determined. It was shown that the activity of investigated systems depends on supramolecular structure of the polymer and on the type of porphyrin-polymer binding in organic solvents. In water, activity of investigated systems depends on supramolecular structure of the polymer only.","PeriodicalId":219206,"journal":{"name":"Current Research on Laser Use in Oncology","volume":"82 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127629868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Double wavelength differential absorption as a technique for early diagnosis of breast cancer 双波长差分吸收作为乳腺癌早期诊断的技术
Current Research on Laser Use in Oncology Pub Date : 2005-08-08 DOI: 10.1117/12.639949
V. Liger, A. Zybin, K. Niemax, Y. Kuritsyn, M. Bolshov
{"title":"Double wavelength differential absorption as a technique for early diagnosis of breast cancer","authors":"V. Liger, A. Zybin, K. Niemax, Y. Kuritsyn, M. Bolshov","doi":"10.1117/12.639949","DOIUrl":"https://doi.org/10.1117/12.639949","url":null,"abstract":"The double-wavelength differential molecular absorption technique with diode lasers is proposed for sensitive detection of functional status of breast tissues. The method is based on the measurement of the transmitted intensity differences of the two beams of diode lasers tuned to selected wavelengths within a broad absorption band of a human breast tissue within 700 - 800 nm spectral range. The strategy for the optimum selection of the diode laser wavelengths and initial adjustment of the detection scheme is developed. The method is demonstrated by the detection of the relative concentrations of two dyes, the optical properties of which are similar to those of a mixture of oxy- and deoxy- hemoglobin. The results of the first clinical tests of the proposed technique are briefly described.","PeriodicalId":219206,"journal":{"name":"Current Research on Laser Use in Oncology","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134439426","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New laser technologies in the clinic of neurosurgery 新激光技术在神经外科临床中的应用
Current Research on Laser Use in Oncology Pub Date : 2005-08-08 DOI: 10.1117/12.640136
V. Stupak, N. Fomichev, S. B. Tsvetovsky, A. B. Dmitriev, V. V. Kobosev, S. Bagaev, A. Mayorov, S. G. Struts
{"title":"New laser technologies in the clinic of neurosurgery","authors":"V. Stupak, N. Fomichev, S. B. Tsvetovsky, A. B. Dmitriev, V. V. Kobosev, S. Bagaev, A. Mayorov, S. G. Struts","doi":"10.1117/12.640136","DOIUrl":"https://doi.org/10.1117/12.640136","url":null,"abstract":"In report summarized more then 10 experience of authors in Novosibirsk Traumatology and orthopedics research institute Neurosurgery clinic on usage of laser technologies in treatment of central nervous system tumors. On the basis of ND-YAG laser application original technologies have been developed and used in surgical treatment of patients with various neurosurgical pathology and protected by 8 Patents of the Russian Federation. 427 patients were operated on with the use of YAG:Nd3+ laser. Out of them 152 patients had extracerebral tumors of various volume and localization, 135 patients - spinal cord tumors, 74 patients - a pathology of cerebrospinal transition (Amold-Chiari syndrome of 1-2 types), and 66 patients - intramedullary tumors of deep localization. Results showed good results of laser technologies usage for central nervous system tumors removal.","PeriodicalId":219206,"journal":{"name":"Current Research on Laser Use in Oncology","volume":"68 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115351684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spectral coordinates in spectra fitting for explicit photodynamic therapy dosimetry 显式光动力治疗剂量法光谱拟合中的光谱坐标
Current Research on Laser Use in Oncology Pub Date : 2005-08-08 DOI: 10.1117/12.640130
E. Kustov, M. Loschenov, L. Lilge
{"title":"Spectral coordinates in spectra fitting for explicit photodynamic therapy dosimetry","authors":"E. Kustov, M. Loschenov, L. Lilge","doi":"10.1117/12.640130","DOIUrl":"https://doi.org/10.1117/12.640130","url":null,"abstract":"In this work a new method for spectra fitting is presented. The method was named spectral coordinates fitting (SCF) because the central equation system is based on spectral coordinates. The method was validated on model spectra and spectra acquired during light intensity measurements during in-vivo Photodynamic Therapy (PDT) of dogs prostates.","PeriodicalId":219206,"journal":{"name":"Current Research on Laser Use in Oncology","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127809214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Photodynamic therapy of tumor-associated pathology of uterine cervix 子宫颈肿瘤相关病理的光动力治疗
Current Research on Laser Use in Oncology Pub Date : 2005-08-08 DOI: 10.1117/12.640046
E. Novikova, O. Trushina, V. Sokolov, E. Filonenko
{"title":"Photodynamic therapy of tumor-associated pathology of uterine cervix","authors":"E. Novikova, O. Trushina, V. Sokolov, E. Filonenko","doi":"10.1117/12.640046","DOIUrl":"https://doi.org/10.1117/12.640046","url":null,"abstract":"We have analyzed the results of photodynamic therapy using light-sensitizing agent \"Photoheme\" in 56 patients - 44 women with pre-cancerous lesions of cervix (group 1) and 12 women with early cervical cancer (group 2). The results were as follows: group 1 - c omplete regression - 3 7 (84%), partial regression - 4 (9,%), stabilization - 2 (4,6%), progression -1 (2,3%); group 2 - complete regression - 8 (66,7%), partial regression - 1 (8,3%), stabilization - 3 (25%). Anti-viral effect was registered in 38 (90,4%) cases after first procedure, in 4 cases - after second procedure.","PeriodicalId":219206,"journal":{"name":"Current Research on Laser Use in Oncology","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130631361","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dermatocosmetologic aspects of treatment of basal-cell skin cancer 皮肤美容方面治疗基底细胞皮肤癌
Current Research on Laser Use in Oncology Pub Date : 2005-08-08 DOI: 10.1117/12.640135
A. V. Geinitz, Ye. F. Stranadko, Zh. M. Yusupova, S. Tkachenko
{"title":"Dermatocosmetologic aspects of treatment of basal-cell skin cancer","authors":"A. V. Geinitz, Ye. F. Stranadko, Zh. M. Yusupova, S. Tkachenko","doi":"10.1117/12.640135","DOIUrl":"https://doi.org/10.1117/12.640135","url":null,"abstract":"The obtained clinical findings demonstrate excellent results after surgical MSC treatment with the application of modem laser surgical technologies. All the operated patients were under oncologist's control during 1.5-2.5 years. In 6 cases we observed topical recurrences which needed a repeated intervention. Thus, our experience of applying LPh for surgical treatment of basal-cell carcinomas of the head and neck dem- onstrate that in the analysed cases it is more reasonable to use two models of laser devices different in their physical parameters. These devices are used at different surgical stages so as to provide a precise effect in laser tumour vaporization within the borders of the healthy tissue, to make better vascular coagulation and laser smoothing of wound surface. Immediate, direct and long-term results of modern surgical lasers' application for treating skin BSC almost in all cases give good and excellent cosmetic effect after such intenventions.","PeriodicalId":219206,"journal":{"name":"Current Research on Laser Use in Oncology","volume":"69 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126419359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Changes in the aqueous phase of cell suspensions and protein solutions induced by a photoexitation of the molecular oxygen (to mechanisms of biological action of low level laser radiation ) 由分子氧的光激发引起的细胞悬浮液和蛋白质溶液的水相变化(到低水平激光辐射的生物作用机制)
Current Research on Laser Use in Oncology Pub Date : 2005-08-08 DOI: 10.1117/12.640184
S. Zakharov, A. Ivanov
{"title":"Changes in the aqueous phase of cell suspensions and protein solutions induced by a photoexitation of the molecular oxygen (to mechanisms of biological action of low level laser radiation )","authors":"S. Zakharov, A. Ivanov","doi":"10.1117/12.640184","DOIUrl":"https://doi.org/10.1117/12.640184","url":null,"abstract":"Temperature-dependent transient processes initiated by a direct photogeneration of singlet oxygen in suspensions of human erythrocytes and solutions of serum albumin are studied. The processes appear as anomalous jumps in the temperature dependences of the deformability coefficient of erythrocytes and the refractive index of the extracellular medium and protein solution. In the temperature regions of anomalous jumps, cells and proteins transfer to a metastable state of a lower activity, but they can be isothermally photoreactivated. Simultaneously, a reversible rearrangement of the aqueous phase occurs near the cell and protein surfaces, accompanied by the formation of an extended corona (hydrogel). The transient processes are interpreted as phase transitions in the membrane of erythrocytes and conformation transitions in proteins. The interaction between erythrocytes and albumin via hydrogel is discovered (hydro-conformational interaction).","PeriodicalId":219206,"journal":{"name":"Current Research on Laser Use in Oncology","volume":"135 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125940610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A new diagnostic device: KINOX 一种新的诊断设备:KINOX
Current Research on Laser Use in Oncology Pub Date : 2005-08-08 DOI: 10.1117/12.639953
A. Zaritsky, G. Zaritskaya, V. Pronin, N. A. Raspopov, M. Fock
{"title":"A new diagnostic device: KINOX","authors":"A. Zaritsky, G. Zaritskaya, V. Pronin, N. A. Raspopov, M. Fock","doi":"10.1117/12.639953","DOIUrl":"https://doi.org/10.1117/12.639953","url":null,"abstract":"A new diagnostic device KINOX created at P N Lebedev Physics Institute is described. With this device it is possible to trace the variations of oxygen permeability in erythrocyte membranes during the blood oxygenation. The molecular mechanism responsible for these variations was explained and experimentally tested at P N Lebedev Physics Institute. The diagnostic method is substantiated capable of estimating physiological reserves of organism basing on the results of blood oxygenation measurements performed with the KINOX. The possible reduction in physiological reserves of organism under the laser action on malignant tumor can be detected in this way.","PeriodicalId":219206,"journal":{"name":"Current Research on Laser Use in Oncology","volume":"40 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121705688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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