Sleep medicine最新文献

{"title":"Connecting clinicians and patients: The language of narcolepsy","authors":"Lucie Barateau ,&nbsp;Anne Marie Morse ,&nbsp;Simerpal K. Gill ,&nbsp;Fabio Pizza ,&nbsp;Chad Ruoff","doi":"10.1016/j.sleep.2024.10.014","DOIUrl":"10.1016/j.sleep.2024.10.014","url":null,"abstract":"<div><div>Narcolepsy is a rare lifelong sleep disorder characterized by excessive daytime sleepiness with variable expression of cataplexy, sleep paralysis, sleep-related hallucinations and disrupted nocturnal sleep. Affected individuals also experience additional impairing symptoms, including (but not limited to) difficulties with attention, memory and concentration, brain fog, mood instability and fatigue, with a substantial impact on everyday life. Diagnostic delays of up to 10 years are common, primarily due to the substantial heterogeneity in clinical presentation of narcolepsy symptoms and presence of significant comorbidities. The disconnect in language used by clinicians and patients could be a factor contributing to diagnostic delays, but it has not been much studied. We followed a two-part approach to investigate the impact of this possible mismatch in language use. Firstly, a comprehensive literature search was conducted to identify publications reporting discrepancies in language relating to narcolepsy symptoms used by clinicians and patients. As a gap in the literature was anticipated, we supplemented the search results with practical strategies based on our clinical experience to facilitate dialog between clinicians and people living with narcolepsy, as well as proposing future research ideas. The findings of the narrative review, complemented by expert clinical opinion, are intended to help clinicians recognize narcolepsy symptoms and to refer patients with suspected narcolepsy, when appropriate. Although it is unknown to what extent a disconnect in language may contribute to diagnostic delays, we hope that better recognition of the varied clinical presentations of narcolepsy will lead to timelier diagnosis and help improve patient outcomes.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"124 ","pages":"Pages 510-521"},"PeriodicalIF":3.8,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142508352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The value of amide proton transfer imaging in assessing brain damage in patients with obstructive sleep apnea","authors":"Ning Wang ,&nbsp;Li Zhang ,&nbsp;Jihua Zhang ,&nbsp;Rongrong Zhang ,&nbsp;Yan Zhao ,&nbsp;Baogen Zhao ,&nbsp;Shichao Wu ,&nbsp;Ruifeng Zhang ,&nbsp;Zeqiang Ji ,&nbsp;Licun Lei ,&nbsp;Wenyuan Wang ,&nbsp;Yong Wang","doi":"10.1016/j.sleep.2024.10.009","DOIUrl":"10.1016/j.sleep.2024.10.009","url":null,"abstract":"<div><h3>Objective</h3><div>To investigate the application value of amide proton transfer (APT) magnetic resonance imaging in evaluating brain damage in patients with obstructive sleep apnea (OSA).</div></div><div><h3>Materials and methods</h3><div>49 OSA patients and 25 healthy individuals matched for age and sex were included as case and control groups. All study participants underwent conventional 3D T1WI and APT imaging of the head. The APT values were measured in each of the brain regions of interest (ROI). To compare the differences in APT values of each brain region between the case and control groups, to compare the differences in the efficacy of APT values of each brain region in diagnosing OSA, and to investigate the correlation between APT values of each brain region and Apnea Hypopnea Index (AHI) and minimum blood oxygen saturation.</div></div><div><h3>Results</h3><div>Compared to the control group, patients with OSA had elevated APT values in several brain regions (P &lt; 0.05), and the diagnostic efficacy of the combined diagnosis of OSA by multiple brain regions is better than that by each brain region alone.Left frontal APT values were positively correlated with AHI in the case group (r = 0.33, P = 0.020).In the case group, the APT values of bilateral frontal lobe, parietal lobe, occipital lobe, left temporal lobe, right thalamus, left internal capsule, left lenticular nucleus, right cerebellar hemisphere and splenium of corpus callosum were negatively correlated with the minimum blood oxygen saturation, and the APT values for each of the above ROIs were positively correlated.</div></div><div><h3>Conclusion</h3><div>APT imaging has a certain value in evaluating brain damage in OSA patients, which may provide a new objective imaging basis for the clinical diagnosis of OSA.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"124 ","pages":"Pages 434-442"},"PeriodicalIF":3.8,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142441188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Objective measures of sleep in adults and older adults with and without depression: A systematic review and meta-analysis","authors":"Andrea Ricciardiello ,&nbsp;Jun Z. Teh ,&nbsp;Aaron K.F. Lam ,&nbsp;Nathaniel S. Marshall ,&nbsp;Sharon L. Naismith ,&nbsp;Angela L. D'Rozario","doi":"10.1016/j.sleep.2024.10.011","DOIUrl":"10.1016/j.sleep.2024.10.011","url":null,"abstract":"<div><div>Sleep architecture is poorly defined in people with depression, especially in older adults. We investigated differences in sleep macro- and micro-architecture between adults and older adults (&gt;50 years) with and without depression.</div><div>A systematic review identified 2135 papers through PubMed, Scopus, Web of Science and Embase databases. Two reviewers excluded articles using PRISMA guidelines. Fifteen articles met inclusion criteria. A random effects model meta-analysis was performed. NICE case-control guidelines were used to assess risk of bias.</div><div>In the fifteen articles, 838 participants underwent objective sleep measurement (406 depression and 432 control). All adults with depression had less total sleep time, delayed sleep onset latency, higher wake after sleep onset, shorter rapid eye movement latency (ROL) and greater rapid eye movement REM density than controls. Two of these studies examined sleep architecture in 62 older adults (31 depression, 31 control). Older adults with depression had more stage 1 sleep, less stage 2 sleep, shorter ROL than older controls with no between-group difference in sleep efficiency, REM sleep or REM density. Six studies had poor case-control selection, which when removed nullified the effects of REM density and REM latency in all adults. Sleep micro-architecture measures could not be meta-analysed due to the limited studies available.</div><div>Adults with depression had moderately worse sleep initiation and continuity than controls. Alterations to REM sleep were observed in adults with depression, however these effects were not robust. Sleep macro-architecture differences were not consistent in younger adults and older adults with depression, compared to relative controls.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"124 ","pages":"Pages 637-648"},"PeriodicalIF":3.8,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital cognitive-behavioral therapy for insomnia in patients with multiple sclerosis: A multiple baseline single-case pilot study","authors":"Sven Alfonsson ,&nbsp;Alva Olofsson Liljeholm ,&nbsp;Camilla Adel ,&nbsp;Milena Lundberg ,&nbsp;Carolyn Cheevers ,&nbsp;Markus Jansson-Fröjmark ,&nbsp;Monica Buhrman","doi":"10.1016/j.sleep.2024.10.010","DOIUrl":"10.1016/j.sleep.2024.10.010","url":null,"abstract":"<div><div>Insomnia has an estimated prevalence of over 20 % in patients with multiple sclerosis (MS) and preliminary evidence suggests that treating insomnia through cognitive behavioral therapy for insomnia (CBT-I) can alleviate fatigue and other secondary symptoms in this population. Video-based CBT-I, an emerging remote treatment modality, has shown promise in previous studies for addressing insomnia in various populations, indicating its potential as an efficient treatment approach for individuals with MS. This pilot study aimed to assess the impact of video-based cognitive behavioral therapy for insomnia (VCBT-I) on individuals with comorbid insomnia and multiple sclerosis (MS). Out of the ten participants, six experienced statistically significant reductions in total wake time during the night, while seven demonstrated clinically significant improvements in waking time, and eight achieved insomnia remission based on the Insomnia Severity Index (ISI). These findings align with prior research indicating the effectiveness of CBT-I in addressing sleep disturbances and its promising potential for insomnia in MS. Moreover, improvements in depression symptoms, as measured by the PHQ-9, and reductions in worry, as assessed by the GAD-7, were observed. Although fatigue outcomes varied, suggesting a potential need for optimal sleep duration, participants reported enhanced quality of life and high treatment satisfaction. These results suggest that VCBT-I is a well-tolerated and effective treatment option for individuals with comorbid MS and insomnia, highlighting its potential to alleviate both sleep-related and psychological symptoms.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"124 ","pages":"Pages 443-452"},"PeriodicalIF":3.8,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142445365","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep disturbances in probable multiple system atrophy","authors":"Malligurki Raghurama Rukmani ,&nbsp;Ravi Yadav ,&nbsp;Binukumar Bhaskarapillai ,&nbsp;Pramod Kumar Pal ,&nbsp;Talakad Narasappa Sathyaprabha","doi":"10.1016/j.sleep.2024.10.013","DOIUrl":"10.1016/j.sleep.2024.10.013","url":null,"abstract":"<div><h3>Background</h3><div>Multiple system atrophy (MSA) is a fatal alpha-synucleinopathy characterized by variable combinations of parkinsonism, autonomic and cerebellar dysfunction. Sleep in MSA is highly compromised due to various sleep disturbances. Disrupted sleep-wake cycles in MSA contribute to poor health-related quality of life and are negative prognostic factors.</div></div><div><h3>Objectives</h3><div>We aimed to study the various sleep disturbances; the effect of parkinsonian and cerebellar phenotypes on sleep; and the correlation of sleep parameters with disease severity in an Asian-Indian cohort of probable MSA patients.</div></div><div><h3>Methods</h3><div>We recruited 60 probable MSA patients (MSA-P = 19; MSA-C = 41). Disease severity was assessed using UPDRS-III, UMSARS-I and UMSARS-II. Detailed history and relevant sleep questionnaires were applied to evaluate the sleep disturbances.</div></div><div><h3>Results</h3><div>Sleep disturbances were universally observed in probable MSA patients in this cohort. These include REM behavior disorder (RBD)-95 %; poor sleep quality-80 %; secondary insomnia and intermittent awakenings-100 %; excessive daytime sleepiness-26 %; risk for obstructive sleep apnea-51.7 % and snoring-85 %. MSA patients reported 38.2 ± 22.9 percentage improvement in sleep with the medications. There was no significant difference between probable MSA-P and MSA-C patients in any of the sleep parameters. Sleep quality was poor in patients with pre-motor RBD than post-motor RBD (p &lt; 0.01). Poor sleep quality had a moderate positive correlation with RBD duration. Disease severity positively correlated with RBD duration and poor sleep quality.</div></div><div><h3>Conclusions</h3><div>Sleep disturbances, the negative prognostic factors, were universally observed in this Asian Indian MSA cohort. This study provides supporting evidence that RBD might play a possible role in MSA disease severity, progression, and sleep quality.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"124 ","pages":"Pages 416-420"},"PeriodicalIF":3.8,"publicationDate":"2024-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142432470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypersomnia and cataplexy in Moebius syndrome","authors":"Antonella Barbieri ,&nbsp;Marco Veneruso ,&nbsp;Lorenzo Chiarella ,&nbsp;Lino Nobili ,&nbsp;Ramona Cordani","doi":"10.1016/j.sleep.2024.10.012","DOIUrl":"10.1016/j.sleep.2024.10.012","url":null,"abstract":"","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"124 ","pages":"Pages 421-423"},"PeriodicalIF":3.8,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142432471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can Sniff Nasal Inspiratory Pressure be a guide in detecting of sleep-disordered breathing in children with Duchenne Muscular Dystrophy?","authors":"Mine Yüksel Kalyoncu ,&nbsp;Yasemin Gokdemir ,&nbsp;Cansu Yilmaz Yegit ,&nbsp;Muruvvet Yanaz ,&nbsp;Aynur Gulieva ,&nbsp;Merve Selcuk ,&nbsp;Şeyda Karabulut ,&nbsp;Neval Metin Çakar ,&nbsp;Almala Pınar Ergenekon ,&nbsp;Yavuz Gündoğdu ,&nbsp;Meltem Sabancı ,&nbsp;Kadir Lale ,&nbsp;Ela Erdem Eralp ,&nbsp;Gülten Öztürk ,&nbsp;Olcay Ünver ,&nbsp;Ali Cemal Yumuşakhuylu ,&nbsp;Dilşad Türkdoğan ,&nbsp;Fazilet Karakoç ,&nbsp;Bulent Karadag","doi":"10.1016/j.sleep.2024.10.004","DOIUrl":"10.1016/j.sleep.2024.10.004","url":null,"abstract":"<div><h3>Purpose</h3><div>Duchenne muscular dystrophy (DMD) is a severe, progressive condition characterized by muscle degeneration and weakness, significantly affecting respiratory function. This study aimed to evaluate the presence of sleep-disordered breathing (SDB) in children with DMD and investigate the relationships between sleep and respiratory function using spirometry, sniff nasal inspiratory pressure (SNIP), and polysomnography (PSG) along with capnography.</div></div><div><h3>Research question</h3><div>Can low SNIP be a guide for detecting respiratory muscle involvement early and determining the right time to perform early PSG and capnography in DMD?</div></div><div><h3>Study design</h3><div>Prospective, observational, cross-sectional study.</div></div><div><h3>Methods</h3><div>This study included DMD patients aged &lt;18 years. Pulmonary function tests were conducted using spirometry and SNIP, and maximum inspiratory and expiratory pressure were measured. PSG and capnography were performed within two weeks after the pulmonary function tests, and their relationships with each other were investigated.</div></div><div><h3>Results</h3><div>The study included 44 children. Obstructive sleep apnea syndrome (OSAS) was present in 70.5 % of patients, while nocturnal hypoventilation was observed in 4.5 %. SNIP values were significantly lower in patients with moderate-to-severe OSAS than in those without OSAS. An SNIP value below 40 cm H2O was associated with a 92.8 % prevalence of OSAS.</div></div><div><h3>Conclusion</h3><div>SNIP is a valuable, noninvasive marker for the early detection of respiratory muscle involvement and SDB in patients with DMD. This study highlights the need for early and regular respiratory monitoring in children with DMD to enhance care and quality of life.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"124 ","pages":"Pages 662-668"},"PeriodicalIF":3.8,"publicationDate":"2024-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142628559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delphi consensus recommendations for the management of chronic insomnia in Canada","authors":"Charles M. Morin ,&nbsp;Atul Khullar ,&nbsp;Rebecca Robillard ,&nbsp;Alex Desautels ,&nbsp;Michael S.B. Mak ,&nbsp;Thien Thanh Dang-Vu ,&nbsp;Walter Chow ,&nbsp;Jeff Habert ,&nbsp;Serge Lessard ,&nbsp;Lemore Alima ,&nbsp;Najib T. Ayas ,&nbsp;James MacFarlane ,&nbsp;Tetyana Kendzerska ,&nbsp;Elliott K. Lee ,&nbsp;Colleen E. Carney","doi":"10.1016/j.sleep.2024.09.038","DOIUrl":"10.1016/j.sleep.2024.09.038","url":null,"abstract":"<div><h3>Objective</h3><div>The lack of current Canadian practice guidelines for the management of insomnia poses a challenge for healthcare providers (HCP) in selecting the appropriate treatment options. This study aimed to establish expert consensus recommendations for the management of chronic insomnia in Canada.</div></div><div><h3>Composition of the committee</h3><div>Sixteen multidisciplinary experts in sleep medicine and insomnia across Canada developed consensus recommendations based on their knowledge of the literature and their practical experience.</div></div><div><h3>Methods</h3><div>The consensus recommendations were developed through a Delphi method. Consensus was reached if at least 75 % of the voting participants “agreed” or “strongly agreed” with the corresponding statements. The quality of supporting evidence was rated using a GRADE rating system.</div></div><div><h3>Report</h3><div>Among 37 recommendations that reached consensus for the management of chronic insomnia, the experts recommend and agree that.</div></div><div><h3>Conclusion</h3><div>These consensus recommendations highlight the need to increase awareness, capacity for, and access to CBT-I; integrate newly approved pharmacotherapy; reduce both self-medication and medications with limited evidence or low risk/benefit ratio.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"124 ","pages":"Pages 598-605"},"PeriodicalIF":3.8,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142553623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nightmares in the elderly: Associations with self-reported executive functions","authors":"Wesley J. Wildman ,&nbsp;Aidan David ,&nbsp;George Hodulik ,&nbsp;John Balch ,&nbsp;David Rohr ,&nbsp;Patrick McNamara","doi":"10.1016/j.sleep.2024.10.001","DOIUrl":"10.1016/j.sleep.2024.10.001","url":null,"abstract":"<div><h3>Study objectives</h3><div>To describe nightmare phenomenology among community dwelling elderly and to test the hypothesis that reduction in cognitive control is associated with nightmare-related phenomenology including nightmare frequency and severity, greater emotional reactivity, imagery immersion, and dream enactment behaviors (DEBs).</div></div><div><h3>Methods</h3><div>Study 1: Survey with multiple regression and ANOVAs on N = 56 people with frequent nightmares plus N = 62 age- and gender-matched controls to quantify the strength of the association between cognitive control variables and nightmare phenomenology. <strong>Study 2</strong>: Computational simulation of nightmare phenomenology in relation to cognitive control to simulate the empirical findings and to assess the underlying causal theory through computationally supported causal inference.</div></div><div><h3>Results</h3><div>Study 1: Regressions demonstrated a strong association between reduction in cognitive control and more extreme nightmare phenomenology, including severity, frequency, daytime effects, and DEBs. Study 2: The computational simulation of nightmare phenomenology in relation to cognitive control is validated relative to regressions from study 1 and offers computational support for the causal theory explaining the associations in study 1.</div></div><div><h3>Conclusions</h3><div>In aging people, decline in executive cognitive functions, cognitive control, and inhibitory processes reduce cognitive control over emotions, thus contributing to unusual nightmare activity, including more extreme nightmare phenomenology such as more severe nightmares, greater emotional reactivity, deeper imagery immersion, and DEBs.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"124 ","pages":"Pages 381-395"},"PeriodicalIF":3.8,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142401372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between grit and insomnia: A population-based study","authors":"Jae Rim Kim ,&nbsp;Jung-A Park ,&nbsp;Hong-Jik Kim ,&nbsp;Jee-Eun Yoon ,&nbsp;Dana Oh ,&nbsp;Hyo Jin Park ,&nbsp;Sang Min Paik ,&nbsp;Woo-Jin Lee ,&nbsp;Daeyoung Kim ,&nbsp;Kwang Ik Yang ,&nbsp;Min Kyung Chu ,&nbsp;Chang-Ho Yun","doi":"10.1016/j.sleep.2024.10.006","DOIUrl":"10.1016/j.sleep.2024.10.006","url":null,"abstract":"<div><h3>Background</h3><div>This study aimed to investigate the association of the grit scale, a personality trait characterized by perseverance and passion, with both the presence and the severity of insomnia in the Korean adult population.</div></div><div><h3>Methods</h3><div>A nationwide population-based cross-sectional survey was conducted through face-to-face interviews using structured questionnaires between September and December 2018 in Korea. Grit was assessed by using the 8-item Short Grit Scale. Participants were categorized into insomnia and non-insomnia groups based on a threshold of 10 on the Insomnia Severity Index (ISI). The association between girt and insomnia was analyzed using multiple linear regression and multivariable logistic regression, controlling for sociodemographic factors, lifestyles, and comorbidities.</div></div><div><h3>Results</h3><div>A total of 2453 participants (49.9 % male; aged 19–92 years) were enrolled in the study. Individual grit scores ranged from 1.75 to 5.00 points (mean [SD], 3.27 [0.42]), and insomnia was present in 16.5 % of the population. The insomnia group exhibited lower grit score compared to the non-insomnia group (3.11 [0.40] vs. 3.30 [0.42], <em>p</em> &lt; 0.001, Cohen's <em>d</em> = 0.46). Grit was negatively associated with ISI scores (β = −0.15, 95 % CI = −0.19, −0.11, <em>p</em> &lt; 0.001) and with having insomnia (OR 0.40, 95 % CI = 0.30, 0.55, <em>p</em> &lt; 0.001), after controlling for covariates.</div></div><div><h3>Conclusions</h3><div>Individuals with higher grit were less likely to have insomnia. Clinicians should consider personality traits, such as grit, in the evaluation and the management of insomnia.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"124 ","pages":"Pages 371-377"},"PeriodicalIF":3.8,"publicationDate":"2024-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142393453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}