Sleep medicine最新文献

{"title":"Obstructive sleep apnea and echocardiographic indicators of elevated pulmonary hypertension probability after pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension","authors":"Caner Çınar ,&nbsp;Şehnaz Olgun Yıldızeli ,&nbsp;Halil Ataş ,&nbsp;Baran Balcan ,&nbsp;Bülent Mutlu ,&nbsp;Bedrettin Yıldızeli ,&nbsp;Yüksel Peker","doi":"10.1016/j.sleep.2026.108827","DOIUrl":"10.1016/j.sleep.2026.108827","url":null,"abstract":"<div><h3>Study objectives</h3><div>We previously demonstrated that 80% of patients with chronic thromboembolic pulmonary hypertension (CTEPH) exhibit sleep-related breathing disorders (SBDs), primarily obstructive sleep apnea (OSA), followed by isolated sleep-related hypoxemia (ISRH). In this follow-up study, we aimed to assess the distribution of SBDs and predictors of echocardiography-based residual pulmonary hypertension (PH) risk after pulmonary endarterectomy (PEA) in the same cohort.</div></div><div><h3>Methods</h3><div>Overnight polysomnography and echocardiography were performed in 24 CTEPH patients approximately 112 ± 65 days after PEA. Residual PH risk was defined as peak tricuspid regurgitation velocity (TRV) &gt; 2.8 m/s and systolic pulmonary artery pressure (SPAP) ≥ 30 mmHg.</div></div><div><h3>Results</h3><div>In the overall cohort, PEA significantly reduced TRV (from 3.7 ± 0.9 to 2.5 ± 0.9 m/s, p &lt; 0.001) and SPAP (58.3 ± 26.9 to 29.8 ± 17.7 mmHg, p &lt; 0.001). Among six patients with preoperative ISRH, two improved, while four developed OSA postoperatively. Of the 16 patients with preoperative OSA, 14 remained in the same category after surgery. Residual PH risk was observed in 13 patients (54.2%), all of whom had OSA, while no residual PH risk was detected in patients without SBDs (p = 0.003). In multivariate logistic regression, postoperative apnea–hypopnea index was independently associated with echo-based residual PH risk (odds ratio 1.19; 95% CI 1.02–1.38; p = 0.025), after adjustment for age, sex, body mass index, and baseline mean pulmonary arterial pressure.</div></div><div><h3>Conclusions</h3><div>PEA improves pulmonary hemodynamics and resolves ISRH in some patients with CTEPH. However, residual PH risk remains frequent and is independently associated with OSA severity. These findings emphasize the importance of systematic screening, early diagnosis, and management of OSA to potentially mitigate residual PH risk and improve postoperative outcomes in CTEPH.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"141 ","pages":"Article 108827"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146143399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gut microbiota, sleep quality, and cognitive function in adults: A systematic review","authors":"Hesam A. Varpaei ,&nbsp;Lorraine B. Robbins ,&nbsp;Mathew J. Reeves ,&nbsp;Pallav Deka ,&nbsp;Fabrice I. Mowbray ,&nbsp;Stuart F. Quan","doi":"10.1016/j.sleep.2026.108834","DOIUrl":"10.1016/j.sleep.2026.108834","url":null,"abstract":"<div><h3>Background</h3><div>Gut microbiota and sleep quality are reported to be important in physiological processes such as cognitive function. Yet, a systematic review examining the effect of both gut microbiota and sleep quality on cognitive function in adults is lacking. Therefore, this study aimed to examine the association between both sleep quality (efficiency, total sleep time) and gut microbiota composition in relation to cognitive function in adults.</div></div><div><h3>Methods</h3><div>This systematic review followed Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. We searched five online databases for original studies on human subjects that assessed cognitive function, sleep quality, and gut microbiota were eligible. The initial search resulted in 1646 titles/abstracts. Following the removal of duplicates and applying eligibility criteria, 21 studies (52% from China; 70.5% cross-sectional; 2,901patients) were included.</div></div><div><h3>Results</h3><div>Sleep quality was assessed both using subjective and objective measures. Cognitive function was mostly evaluated with the Montreal Cognitive Assessment (38% of studies), while gut microbiota was predominantly analyzed using 16S rRNA sequencing (62%). Interestingly, no study was found that assessed gut microbiota, sleep, and cognitive function in individuals with cardiovascular disease. Observational findings consistently link objective sleep measures (efficiency, total sleep time) to greater gut microbial diversity in healthy adults, which correlates positively with better cognitive function. This relationship is mediated by microbial diversity relating significantly to inter-network functional connectivity in the brain. Conversely, pathological findings revealed that chronic insomnia is defined by a distinct microbiota dysbiosis (decreased Firmicutes/Actinobacteria and increased Bacteroidetes). Interventional studies showed that probiotic supplementation modulated gut composition, reduced physiological stress markers, and enhanced sleep quality and cognitive function in patients with cognitive impairment.</div></div><div><h3>Conclusion</h3><div>This systematic review confirms a complex and reciprocal relationship between sleep quality, gut microbial composition, and cognitive function in adults; therefore, optimal sleep and cognition are linked to greater gut microbial diversity. Higher microbial diversity correlates with superior objective sleep metrics and better cognitive function, mediated by enhanced inter-network functional connectivity in the brain. No studies assessed this triad (sleep, microbiota, and cognitive function) in individuals with cardiovascular diseases, marking a significant research gap.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"141 ","pages":"Article 108834"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146166772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of an automated sleep apnea scoring algorithm via the Wesper Lab home sleep apnea test","authors":"Chelsie Rohrscheib ,&nbsp;Antonio Artur Moura ,&nbsp;Janna Raphelson ,&nbsp;Jeremy E. Orr ,&nbsp;Ruchir P. Patel ,&nbsp;Atul Malhotra","doi":"10.1016/j.sleep.2026.108828","DOIUrl":"10.1016/j.sleep.2026.108828","url":null,"abstract":"<div><div>This study evaluated the performance of the Wesper Lab home sleep apnea test (HSAT) artificial intelligence (AI) automated scoring algorithm under both in-laboratory and real-world conditions. We conducted a multi-tiered validation using two datasets and three analyses. The primary analysis compared apnea–hypopnea index (AHI) and central apnea index (CAI) from Wesper Lab HSATs with simultaneous polysomnography (PSG) scored by blinded technologists (n <span><math><mo>=</mo></math></span> 44). The secondary analysis evaluated blinded scoring of raw Wesper Lab signals from the same 44 patients: first by a single scorer, then by two additional scorers to assess inter-scorer consistency. The tertiary analysis examined clinical HSATs (n <span><math><mo>=</mo></math></span> 139) in which algorithm-derived AHI was compared with expert rescoring across 11 independent clinics. Agreement metrics included Pearson correlation, Bland-Altman analysis, and confusion matrices. Primary analysis: the algorithm showed strong correlation with PSG for AHI (r <span><math><mo>=</mo></math></span> 0.90) and CAI (r <span><math><mo>=</mo></math></span> 0.82) with minimal bias on Bland-Altman analysis. Secondary analysis: the correlation was r <span><math><mo>=</mo></math></span> 0.95 with minimal bias. Across three scorers, correlation remained <span><math><mrow><mo>≥</mo><mn>0</mn><mo>.</mo><mn>93</mn></mrow></math></span>. Tertiary analysis: correlation was r <span><math><mo>=</mo></math></span> 0.98 with minimal bias. These findings demonstrate that the Wesper Lab autoscoring algorithm is a reliable tool for obstructive sleep apnea and central apnea event detection, supporting its role as an HSAT platform that enhances accessibility to sleep apnea diagnosis.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"141 ","pages":"Article 108828"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146166863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Left hand sleep masturbation in a right-handed male patient with sexsomnia","authors":"Mathilde Brice ,&nbsp;Ana-Zenovia Gales ,&nbsp;Valérie Attali ,&nbsp;Mahaut Chauvin ,&nbsp;Isabelle Arnulf","doi":"10.1016/j.sleep.2026.108823","DOIUrl":"10.1016/j.sleep.2026.108823","url":null,"abstract":"<div><div>Sexsomnia is a NREM parasomnia characterized by involuntary sexual behavior during confusional arousal. Video examples are rare. Here we present the case of a man who was accused of sexually assaulting his girlfriend during the night but had no memory of doing so. During a video polysomnography, he masturbated in his sleep with his left hand during the N2 and N3 sleep stages, confirming sexsomnia. However, he always masturbated with his right hand when awake. Treatment with gabapentin did not alleviate sexsomnia and triggered obstructive sleep apnea, which improved when the treatment was replaced with paroxetine. The effect of paroxetine on sexsomnia was unknown. This case supports the concept of automatic behavior in sexsomnia.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"141 ","pages":"Article 108823"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146120049","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of melatonin enriched with L-Tryptophan and 5-Hydroxytryptophan on sleep parameters in children with neurodevelopmental disorders","authors":"Francy Cruz-Sanabria ,&nbsp;Giovanni Cenerini ,&nbsp;Simone Bruno ,&nbsp;Raffaele Ferri ,&nbsp;Simona Fiori ,&nbsp;Ugo Faraguna","doi":"10.1016/j.sleep.2026.108818","DOIUrl":"10.1016/j.sleep.2026.108818","url":null,"abstract":"<div><h3>Introduction</h3><div>Melatonin plays a key role in sleep regulation. Combining melatonin with its precursors, L-tryptophan (LT) and 5-Hydroxytryptophan (5HTP), may influence sleep-related outcomes, but evidence in children with neurodevelopmental disorders (NDDs) is limited. This exploratory study compares the effects of melatonin combined with 5HTP (M-5HTP) and melatonin combined with LT (M-LT) on sleep disorders in children with NDDs.</div></div><div><h3>Methods</h3><div>This single-center, randomized pilot comparative trial involved children under five years of age with NDDs free of sleep-inducing drugs. Baseline evaluations and actigraphy monitoring were performed. Children were randomly assigned to either M-5HTP (1 mg Melatonin +10 mg 5HTP) or M-LT (1 mg Melatonin +20 mg LT) treatment at 8 p.m. for at least four weeks. Post-treatment actigraphy monitoring assessed sleep parameters.</div></div><div><h3>Results</h3><div>Of 51 screened children, 26 were enrolled and 13 completed the study (M-5HTP: 9, M-LT: 4). No statistically significant between-group differences in change scores were observed. Within-group analyses showed a significant reduction in the Sleep Movement Index (SMI) from baseline to follow-up in the M-5HTP group (T0: 6.55; T1: 1.25; p=0.006), whereas no significant changes were observed in the M-LT group.</div></div><div><h3>Discussion</h3><div>In this exploratory pilot study, a within-group reduction in nocturnal motor activity was observed among M-5HTP completers. Given the small sample size, high attrition rate, and limited statistical power, these findings should be interpreted cautiously and considered hypothesis-generating.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"141 ","pages":"Article 108818"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146126589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Many types of comorbidities are associated with clinically diagnosed insomnia in United States military service members","authors":"Joseph J. Knapik ,&nbsp;Ryan A. Steelman ,&nbsp;John A. Caldwell ,&nbsp;Daniel W. Trone ,&nbsp;Harris R. Lieberman","doi":"10.1016/j.sleep.2026.108820","DOIUrl":"10.1016/j.sleep.2026.108820","url":null,"abstract":"<div><h3>Objectives</h3><div>This cross-sectional investigation examined associations between clinically diagnosed insomnia (CDI) and comorbid conditions in United States military service members (SMs).</div></div><div><h3>Methods</h3><div>A stratified random sample of SMs completed an on-line questionnaire assessing their demographic and lifestyle characteristics. Diagnosed medical conditions for a six-month period prior to questionnaire completion were obtained from a comprehensive military electronic medical surveillance system and grouped into 18 general (largely systemic) and 30 specific clinically diagnosed medical categories (CDMCs). CDMC prevalence odds was compared among those with (n = 771) and without (n = 25,909) CDI.</div></div><div><h3>Results</h3><div>After adjustments for potentially confounding demographic and lifestyle characteristics, CDI was associated with higher odds of a diagnosis in 17 of the general CDMCs and 26 of the specific CDMCs. The five general CDMCs with the largest differences between those with and without CDI were mental/behavioral diseases (odds ratio [OR] = 7.68, 95% confidence interval [95%CI] = 6.54–9.01), signs/symptoms/abnormal labs (OR = 4.99, 95%CI = 4.19–5.93), diseases of the musculoskeletal system (OR = 4.43, 95%CI = 3.72–5.28), endocrine/nutritional/metabolic diseases (OR = 2.97, 95%CI = 2.47–3.58), and diseases of the digestive system (OR = 2.68, 95%CI = 2.18–3.28). The five specific CDMCs with the highest adjusted odds among those with and without CDI were sleep-related movement disorder (OR = 14.68, 95%CI = 9.26–23.26), fibromyalgia (OR = 14.14, 95%CI = 5.74–34.80), post-traumatic stress disorder (OR = 12.94, 95%CI = 10.09–16.59), anxiety (OR = 9.40, 95%CI = 7.71–11.46), and traumatic brain injury (OR = 8.52, 95%CI = 5.93–12.24). Prevalence of CDI increased as the number of CDMCs increased: SMs with 0–1, 2–3, 4–5 and ≥6 general CDMCs had CDI prevalences of 0.5%, 3.2%, 6.7%, and 10.9%, respectively.</div></div><div><h3>Conclusion</h3><div>In a young, physically active population CDI was associated with many CDMCs involving multiple physiological systems.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"141 ","pages":"Article 108820"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146171875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Circadian gene expression in adolescents: Associations with concurrent circadian disruption and subsequent changes in cardiometabolic risk measures","authors":"Donghan Su ,&nbsp;Jaclyn M. Goodrich ,&nbsp;Jennifer T. Lee ,&nbsp;Dana C. Dolinoy ,&nbsp;Karen E. Peterson ,&nbsp;Ronald D. Chervin ,&nbsp;Helen J. Burgess ,&nbsp;Martha María Téllez-Rojo ,&nbsp;Alejandra Cantoral ,&nbsp;Libni Torres-Olascoaga ,&nbsp;Maricruz Tolentino ,&nbsp;Peter X.K. Song ,&nbsp;Louise M. O'Brien ,&nbsp;Erica C. Jansen","doi":"10.1016/j.sleep.2026.108819","DOIUrl":"10.1016/j.sleep.2026.108819","url":null,"abstract":"<div><h3>Objectives</h3><div>Circadian disruption has been linked to adverse metabolic health. Adolescents are particularly susceptible to circadian disruptors, such as delayed sleep onset and social jetlag, which may have sex-specific effects. However, evidence linking these disruptors with circadian gene expression and subsequent cardiometabolic risk remains limited.</div></div><div><h3>Methods</h3><div>Our study included 203 adolescents (53% females, median age 13.6 years) from the ELEMENT cohort in Mexico City. Sleep was assessed via 7-day wrist actigraphy. A fasting venipuncture blood sample was collected between 8:00 a.m. and 12:00 p.m. RNA was isolated from blood leukocytes and sequenced to determine the relative expression of genes. We conducted differential gene expression analysis for 12 core clock genes in relation to sleep midpoint and social jetlag, adjusting for sleep duration and other potential confounders. We further evaluated how circadian gene expression associated with changes in adiposity, glucose metabolism, blood pressure, and lipid profiles over two years using linear regression.</div></div><div><h3>Results</h3><div>Later sleep midpoint (per 1-h increase) was associated with reduced mid-morning expression of four circadian genes: <em>RORA</em> (log2 fold change [LFC]: −0.190; <em>P</em> value: 0.001), <em>RORC</em> (LFC: −0.147; <em>P</em> value: 0.039), <em>CLOCK</em> (LFC: −0.141; <em>P</em> value: 0.019), and <em>NR1D2</em> (LFC: −0.093; <em>P</em> value: 0.029). Additionally, expression levels of several clock genes (<em>CRY1, NR1D2, BMAL1,</em> and <em>PER1-3</em>) were associated with changes in metabolic biomarkers over two years in sex-specific patterns. For instance, <em>NR1D2</em> showed a negative association with fasting glucose among females (β: −0.0012; <em>P</em> value: 0.020), while demonstrating positive associations with LDL cholesterol (β: 0.0023; <em>P</em> value: 0.002) and total cholesterol (β: 0.0016; <em>P</em> value: 0.028) among males.</div></div><div><h3>Conclusions</h3><div>Expression of core clock genes was linked to circadian disruption and changes in cardiometabolic risk factors in a sex-specific manner among adolescents. Our findings provide novel insights into potential biological mechanisms underlying associations of circadian disruption with cardiometabolic health.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"141 ","pages":"Article 108819"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146158627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical phenotypes and predictors of adherence to continuous positive airway pressure therapy in obstructive sleep apnoea: A multicentre cohort study","authors":"Karin Jeppesen ,&nbsp;Poul Jørgen Jennum ,&nbsp;Caroline Moos ,&nbsp;Rikke Ibsen ,&nbsp;Michael Ibsen ,&nbsp;Asbjørn Kørvel-Hanquist ,&nbsp;Preben Homøe ,&nbsp;Eva Kirkegaard Kiaer ,&nbsp;Helene Skjøt-Arkil","doi":"10.1016/j.sleep.2026.108822","DOIUrl":"10.1016/j.sleep.2026.108822","url":null,"abstract":"<div><h3>Purpose</h3><div>Obstructive Sleep Apnoea (OSA) is a highly prevalent disease often treated with CPAP therapy, but long-term adherence remains a challenge. This study aimed to explore which phenotypes of OSA patients are more or less likely to achieve high adherence to CPAP therapy, based on pre-treatment characteristics.</div></div><div><h3>Methods</h3><div>We analysed demographic, socioeconomic, and clinical characteristics across predefined CPAP adherence groups (high, low, and no adherence) in a multicentre cohort of newly diagnosed OSA patients. Multivariate logistic regression was used to assess predictive accuracy, and observed patterns were synthesised into rule-based clinical phenotypes.</div></div><div><h3>Results</h3><div>Among 2845 patients, 41% were highly adherent, 20% had low adherence, and 39% were non-adherent after one year. High adherence was associated with cohabitation, higher education, employment, and greater disease severity. Low or no adherence was linked to comorbidity burden and social vulnerability. The predictive model yielded an accuracy of 60%. Based on group-level differences and model outputs, three clinically reasoned phenotypes were identified: (1) Symptomatic severe OSA with social support, (2) Multimorbidity-dominated, and (3) Non-employed working-age adults.</div></div><div><h3>Conclusion</h3><div>Distinct demographic, socioeconomic, and clinical profiles were associated with CPAP adherence. The identified phenotypes offer a practical framework for understanding adherence variation and may support more individualised approaches to treatment and follow-up.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"141 ","pages":"Article 108822"},"PeriodicalIF":3.4,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146143434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-sectional associations between actigraphy-measured sleep and 24-h ambulatory blood pressure phenotypes among self-reported short sleepers with elevated blood pressure","authors":"Joshua Landvatter ,&nbsp;Adam Bress ,&nbsp;Jenniffer Duffecy ,&nbsp;Sara E. Simonsen ,&nbsp;Chelsea Allen ,&nbsp;Kelly Baron","doi":"10.1016/j.sleep.2026.108780","DOIUrl":"10.1016/j.sleep.2026.108780","url":null,"abstract":"<div><h3>Background</h3><div>Nocturnal blood pressure (BP) phenotypes predict cardiovascular risk, yet most prior work relies on self-reported sleep rather than actigraphy with ambulatory BP monitoring (ABPM).</div></div><div><h3>Objective</h3><div>To test whether actigraphy-measured total sleep time (TST) and sleep efficiency (SE) are associated with nocturnal BP phenotypes in adults with elevated BP and habitual short sleep.</div></div><div><h3>Methods</h3><div>Baseline data from adults with elevated clinic BP and self-reported sleep &lt;7 h/night included approximately seven nights of wrist actigraphy and 24-h ABPM. Linear models estimated continuous outcomes, and Poisson regression estimated prevalence ratios (PRs) for systolic/diastolic non-dipping and asleep hypertension across unadjusted, demographic-adjusted, and fully adjusted models.</div></div><div><h3>Results</h3><div>Longer TST was associated with a lower prevalence of diastolic non-dipping in unadjusted (PR per 10 min = 0.989, 95 % CI 0.981–0.997) and demographic-adjusted models (PR = 0.991, 95 % CI 0.984–0.997), with attenuation in fully adjusted models. SE was positively associated with systolic dipping in unadjusted models (β = 0.002, p = 0.036) and was nonsignificant after adjustment. Neither TST nor SE predicted asleep hypertension.</div></div><div><h3>Conclusions</h3><div>Among short-sleeping adults with elevated BP, longer actigraphy-measured TST relates to more favorable nocturnal BP, specifically lower diastolic non-dipping, although effects attenuate with full adjustment. Findings support integrating actigraphy with ABPM to improve characterization of nocturnal BP phenotypes.</div></div>","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"140 ","pages":"Article 108780"},"PeriodicalIF":3.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145980741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to “The effects of transcranial magnetic stimulation on patients with chronic insomnia: a prospective functional near-infrared spectroscopy study” [Sleep Med. 131 (2025) 106517]","authors":"Xiangrui Liu ,&nbsp;Shijing Wang ,&nbsp;Xiuqing Niu ,&nbsp;Ziming Liu ,&nbsp;Xianguo Meng","doi":"10.1016/j.sleep.2026.108767","DOIUrl":"10.1016/j.sleep.2026.108767","url":null,"abstract":"","PeriodicalId":21874,"journal":{"name":"Sleep medicine","volume":"140 ","pages":"Article 108767"},"PeriodicalIF":3.4,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145998928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}