Pre-stroke subjective sleep quality predicts 1-year clinical outcomes in patients with ischemic stroke or transient ischemic attack: A national cohort study
Jianyu Dong , Shuo Wang , Yang Yang , Anxin Wang , Yijun Zhang , Ning Zhang , Chunxue Wang , Yongjun Wang
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引用次数: 0
Abstract
Background
Sleep quality may be a predictor of outcomes following ischemic stroke. This study aims to investigate the impact of pre-stroke subjective sleep quality on clinical outcomes in stroke patients.
Methods
Patients diagnosed with acute ischemic stroke (AIS) or transient ischemic attack (TIA) were recruited from China National Stroke Registry-III. The Pittsburgh Sleep Quality Index (PSQI) was used to evaluate pre-stroke subjective sleep quality. Cox regression was to explore the relationship between PSQI and recurrent stroke, mortality, and composite vascular events; logistic regression was used for poor functional outcome.
Results
A total of 2,266 patients were enrolled. After 1 year of follow-up, 44 (1.9 %) individuals died, 180 (7.9 %) individuals experienced stroke recurrence, 195 (8.6 %) individuals experienced composite vascular events, and 172 (7.6 %) individuals had poor functional outcome. Patients in the highest quartile of PSQI score (score range: 10–20) exhibited a significantly increased risk of mortality (HR = 3.73, 95 % CI = 1.24–11.22) and poor functional outcome (OR = 2.15 95 % CI = 1.27–3.63) when compared with patients in the lowest quartile (score range: 3–5).
Conclusions
Pre-stroke poor subjective sleep quality independently predicts 1-year mortality and poor functional outcome in patients with AIS or TIA.
期刊介绍:
Sleep Medicine aims to be a journal no one involved in clinical sleep medicine can do without.
A journal primarily focussing on the human aspects of sleep, integrating the various disciplines that are involved in sleep medicine: neurology, clinical neurophysiology, internal medicine (particularly pulmonology and cardiology), psychology, psychiatry, sleep technology, pediatrics, neurosurgery, otorhinolaryngology, and dentistry.
The journal publishes the following types of articles: Reviews (also intended as a way to bridge the gap between basic sleep research and clinical relevance); Original Research Articles; Full-length articles; Brief communications; Controversies; Case reports; Letters to the Editor; Journal search and commentaries; Book reviews; Meeting announcements; Listing of relevant organisations plus web sites.