Sleep Science最新文献

{"title":"Sleep Quality and Duration Can Influence Junior Physicians' Performance in High-Level Assessments for Residency Programs.","authors":"Julio Torales, Carlos Mena-Canata, Macarena Morínigo, Karen Falloon, Matías Cantero, Sofía Gauto, Nicolás López, Marcelo Vargas, Marcelo O'Higgins, Tomás Caycho-Rodríguez, Antonio Ventriglio, João Mauricio Castaldelli-Maia, Iván Barrios","doi":"10.1055/s-0045-1805060","DOIUrl":"10.1055/s-0045-1805060","url":null,"abstract":"<p><strong>Objective: </strong>To assess the sleep quality and duration among junior physicians in Paraguay during the month and night prior to their assessment for entry into primary specialty medical residency programs.</p><p><strong>Materials and methods: </strong>A self-administered survey based on the Pittsburgh Sleep Quality Index (PSQI) was distributed to junior physicians after their National Commission for Medical Residencies (Comisión Nacional de Residencias Médicas - CONAREM, in Spanish) written evaluation. The survey collected data on sleep patterns during the month and night prior to the assessment. The responses were analyzed and matched with physicians' CONAREM scores.</p><p><strong>Results: </strong>The response rate of the survey was 66.3% (270/407 physicians). Among the participants, 150 (55.5%) reported a very poor sleep quality (PSQI > 10). Women scored significantly higher on the PSQI ( <i>p</i>  = 0.013). A significant association was found between the quality of sleep on the night prior to the CONAREM evaluation and the reported evaluation scores (F-test = 3.55, degree of freedom [df] = 3, <i>p</i>  = 0.019). In fact, the night before the written evaluation, 215 participants (79.6%) slept for ≤ 6 hours. A linear relationship was found between the duration of sleep of physicians in the night before the CONAREM written evaluation and the total score obtained in that evaluation (r = 0.200, <i>p</i>  < 0.001), suggesting that the more hours they slept, the higher the score they reported.</p><p><strong>Conclusion: </strong>The quality and duration of junior physicians' sleep the night before the high-stakes evaluation positively correlated with their performance scores. These findings highlight the importance of adequate sleep for optimal cognitive performance in high-stress situations.</p>","PeriodicalId":21848,"journal":{"name":"Sleep Science","volume":"18 3","pages":"e272-e280"},"PeriodicalIF":1.8,"publicationDate":"2025-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effects of Constant Light and Running-Wheel Access in Middle-Aged Female C57BL6/J Mice.","authors":"Fernanda Medeiros Contini, Samantha G Burke, John C Price, Alexander T McFarland, Eric W Joseph, Cloey A Murphy, Meredith E Burns, Julie M Michaud, Joseph A Seggio","doi":"10.1055/s-0044-1791234","DOIUrl":"10.1055/s-0044-1791234","url":null,"abstract":"<p><p><b>Objective</b>  Chronic light exposure is associated with poorer mental and physical health. Many groups are chronically exposed to light due to their work schedule, including night-shift nurses. The present study aims to determine if middle-aged female mice have an increased vulnerability to chronic light exposure compared with younger individuals. <b>Materials and Methods</b>  Young and middle-age female mice were housed in cages with or without running wheels and were exposed to either a 12:12-hour light:dark cycle or constant light (LL). All mice were assayed for circadian locomotor activity and anxiety-like behaviors, and weight, food consumption, and estrogen receptor beta (ERβ) levels were measured. <b>Results</b>  Middle-aged mice exhibited longer circadian periods in LL, reduced circadian power, and increased food consumption compared with young mice. LL increased novelty-induced activity and reduced ERβ regardless of age. <b>Discussion</b>  These results indicate that middle-aged females may have an increased susceptibility to the negative circadian consequences caused by constant bright light exposure.</p>","PeriodicalId":21848,"journal":{"name":"Sleep Science","volume":"18 2","pages":"e201-e208"},"PeriodicalIF":1.0,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12263212/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictors and Factors Associated with Insomnia in a Brazilian Sample: A Cross-Sectional Study.","authors":"Isabela Mayumi Nishino Aizawa, Felipe Alckmin-Carvalho, Helder Sergio Lira Soares Filho, Rosa Hasan, Andrea Cecilia Toscanini, Renatha El Rafihi-Ferreira","doi":"10.1055/s-0045-1806953","DOIUrl":"10.1055/s-0045-1806953","url":null,"abstract":"<p><strong>Objective: </strong>Chronic insomnia is associated with various functional and mental health impairments. The present study aimed to evaluate variables potentially associated with insomnia in a Brazilian sample.</p><p><strong>Materials and methods: </strong>The study was conducted in a psychiatric hospital of a public medical school in the city of São Paulo, Brazil. The sample included 1,435 adults with a mean age of 38.3 years. Participants were divided into two groups: one with individuals diagnosed with insomnia (according to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition and the Insomnia Severity Index) and a comparison group without the diagnosis. The Hospital Anxiety and Depression Scale (HADS) was used to assess psychopathological variables (anxiety and depression) and sociodemographic and anthropometric questionnaires to provide further characterization of the sample. Multivariable binary logistic regression analyses were performed.</p><p><strong>Results: </strong>Male sex and lacking a university degree were associated with increased odds of insomnia, with average increases of 1.93 and 1.89, respectively. Each additional year of age and each additional point on the depression and anxiety increased the likelihood of insomnia by averages of 1.05, 1.18, and 1.40, respectively.</p><p><strong>Conclusion: </strong>This study provides evidence of associations between biopsychosocial factors and insomnia, suggesting the potential for developing preventive and treatment protocols for this condition.</p>","PeriodicalId":21848,"journal":{"name":"Sleep Science","volume":"18 3","pages":"e292-e300"},"PeriodicalIF":1.8,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440602/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sleep, Musculoskeletal Injuries, and Hormonal Status in Different Training Stages in Adolescent Athletes.","authors":"Luísa de Sousa Nogueira Freitas, Samuel Penna Wanner, Samuel Silva, Eduardo Stieler, Fernanda Viegas Paulo, Marina Costa Pinto, Lucas Alves Facundo, Marco Tulio de Mello, Andressa Silva","doi":"10.1055/s-0045-1802646","DOIUrl":"https://doi.org/10.1055/s-0045-1802646","url":null,"abstract":"<p><p><b>Objective</b>  This study aimed to compare sleep, musculoskeletal injuries, and testosterone and cortisol levels in different training stages in adolescent athletes, and to investigate the association between these variables. <b>Materials and Methods</b>  The study has a prospective cohort design, and the sample consisted of 19 adolescent track and field athletes. They were followed for six months, with evaluations done at three different training phases: preparatory, competitive, and post-competitive. In each phase, we evaluated their sleep through actigraphy for 10 days and testosterone and cortisol levels through saliva samples. The incidence of injuries was obtained through the physical therapy department. <b>Results</b>  In the post-competitive phase, the athletes presented a longer total sleep time (TST) than the competitive phase. Moreover, a shorter wakefulness after sleep onset was observed in the post-competitive and competitive phases compared with the preparatory phase. Furthermore, cortisol levels were higher in the preparatory phase than in the post-competition phase. On the other hand, no differences were observed in the incidence of injuries and testosterone, nor was there a correlation between the variables. <b>Discussion</b>  Adolescent track and field athletes had a higher TST in the post-competitive phase and more fragmented sleep in the pre-competitive and competitive phases. On the other hand, higher cortisol was observed in the preparatory phase, however, there were no correlations between sleep, hormones, and the incidence of injuries.</p>","PeriodicalId":21848,"journal":{"name":"Sleep Science","volume":"18 1","pages":"e37-e43"},"PeriodicalIF":1.0,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12020576/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Physical Exercise on Sleep Quality and Depressive Symptoms in Adults: A Systematic Review and Meta-Analysis.","authors":"José Ricardo Vieira de Almeida, Gleydson Vieira da Silva Barros, Vitor José Monteiro Borges da Silva Valente, Welyson Lima Santana, Elton Carlos Felinto Dos Santos, José Lucas Porto Aguiar, Breno Quintella Farah, Ozeas de Lima Lins Filho","doi":"10.1055/s-0045-1806954","DOIUrl":"10.1055/s-0045-1806954","url":null,"abstract":"<p><p>Improvements in sleep quality and depressive symptoms are considered a cornerstone of adult health. Physical exercise is one of the interventions used to treat people with sleep disorders and improve mental health. However, there is no standardization regarding the physical exercise protocols and their effects on sleep quality and depressive symptoms in adults. The present study aims to verify, through a systematic review and meta-analysis, the effect of physical exercise on sleep quality and symptoms of depression in adults. This study adhered to the guidelines of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement and was registered in the International Prospective Register of Systematic Reviews (PROSPERO). The PubMed, Cochrane Library, and Scopus databases were used to identify relevant original articles and clinical trials. Analysis was performed with Review Manager (RevMan) software (The Cochrane Collaboration, London, United Kingdom), version 5.4. The study included men and women over 18-years-old, with physical exercise as the intervention. The studies included pre- and postevaluation of sleep quality and depressive symptoms. A total of 931 articles were found, of which 15 met the eligibility criteria, encompassing 940 participants. Physical exercise significantly improved sleep quality (mean difference: -1.19; 95% confidence interval [95%CI]: -1.66 to -0.73) and depressive symptoms (mean difference: -3.51; 95%CI: -4.66 to -2.36). Aerobic exercise was the most common and effective for both outcomes. Thus, physical exercise was effective in improving sleep quality and depressive symptoms in adults. Additional studies, however, should be performed to confirm these findings.</p>","PeriodicalId":21848,"journal":{"name":"Sleep Science","volume":"18 3","pages":"e347-e357"},"PeriodicalIF":1.8,"publicationDate":"2025-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440605/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Napping Habit and Risk Factors for Cardiovascular Disease: Does It Matter if It Is Sunday?","authors":"Cristina Kano Inazumi, Carla Renata Silva Andrechuk, Thaís Moreira São-João, Marilia Estevam Cornélio, Roberta Cunha Matheus Rodrigues, Maria Filomena Ceolim","doi":"10.1055/s-0045-1805061","DOIUrl":"10.1055/s-0045-1805061","url":null,"abstract":"<p><strong>Objective: </strong>To assess the relationships involving the habit of napping and the risk factors for cardiovascular diseases.</p><p><strong>Materials and methods: </strong>We conducted a cross-sectional study with 563 participants (mean age: 45.0 ± 8.5 years; 56.7% of female subjects). The variables assessed were sociodemographic characteristics, lifestyle and health habits, clinical variables, and napping habits (intentionality and allocation on weekdays or on weekends). The statistical tests used were the Mann-Whitney and Kruskal-Wallis tests followed by Dunn's post-hoc test and Pearson's Chi-squared. Modified multiple Poisson regression models and multiple linear regression models were adjusted.</p><p><strong>Results: </strong>In total, 56.6% of the participants napped (43.2% during the week and 51.8% on weekends). Unintentional napping predominated on weekdays (22.6%), and intentional napping on weekends (29.7%). Those who intentionally napped on weekdays presented higher serum lipid profile values; those who napped unintentionally on weekdays or on weekends presented higher glycated hemoglobin (HbA1c) values. Age, education, race, marital status, alcohol consumption, and physical activity were associated with increased body mass index (BMI), HbA1c, total cholesterol, high-density lipoprotein (HDL) and non-HDL cholesterol, and triglycerides. Intentional and unintentional napping remained independent risk factors for increased HbA1c and lipid profile.</p><p><strong>Conclusion: </strong>Naps can represent a warning sign for health professionals to start or maintain an individual's follow-up. The present study contributes to the literature by identifying that the habit of intentional napping, especially on weekdays, is associated with changes in the lipid profile.</p>","PeriodicalId":21848,"journal":{"name":"Sleep Science","volume":"18 3","pages":"e262-e271"},"PeriodicalIF":1.8,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440592/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the Monotonous Discussion of ChatGPT Use in Academic Writing: Expectations for Sleep Science Researchers.","authors":"Shigeki Matsubara","doi":"10.1055/s-0045-1805062","DOIUrl":"10.1055/s-0045-1805062","url":null,"abstract":"","PeriodicalId":21848,"journal":{"name":"Sleep Science","volume":"18 3","pages":"e369-e370"},"PeriodicalIF":1.8,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440594/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility of High-Resolution Oximeter Plus Actigraphy Combined with a Cloud-Based Algorithm for the Detection of Obstructive Sleep Apnea in Children with Craniofacial Anomalies.","authors":"Sergio Henrique Kiemle Trindade, Fábio Luiz Banhara, Leide Vilma Fidélis da Silva, Sara Quaglia de Campos Giampá, Lais Mota Furtado Sena, Ivy Kiemle Trindade-Suedam","doi":"10.1055/s-0045-1802967","DOIUrl":"10.1055/s-0045-1802967","url":null,"abstract":"<p><strong>Objective: </strong>To verify the feasibility of high-resolution oximeter plus actigraphy combined with a cloud-based algorithm for the detection of obstructive sleep apnea (OSA) in children with craniofacial anomalies.</p><p><strong>Materials and methods: </strong>In the present prospective, cross-sectional study, we evaluated children previously submitted to primary surgical palate repair with a genetically confirmed diagnosis of Treacher Collins syndrome (TCS), non-syndromic Robin sequence (NSRS), or non-syndromic cleft palate (NSCP). The children underwent a clinical evaluation, had their anthropometric measures taken, and were submitted to OSA detection using high-resolution oximeter plus actigraphy combined with a cloud-based algorithm (Biologix Sleep Test, Biologix Sistemas S.A., São Paulo, SP, Brazil).</p><p><strong>Results: </strong>In total, 64 children (TCS: n = 16; NSRS: n = 29; NSCP: n = 19) were included in the final analysis (mean age: 10 ± 2 years; 64% of female patients). The Biologix Sleep Test showed that 59 patients (92%) presented OSA according to the oxygen desaturation index (ODI): 36 (56%) were diagnosed with mild OSA, 19 (30%), with moderate OSA, and 4 (6%), with severe OSA. The high-resolution oximeter recording showed excellent signal quality in 94.53 ± 5.29% of the exams, with a success rate of exams on the first night of 90%. No significant difference was found in terms of ODI among the subgroups ( <i>p</i>  > 0.05). A significant relationship was observed between increased ODI with greater hypoxic burden and lower estimated sleep efficiency. The multiple linear regression analysis demonstrated a significant association between changes in total ODI with lower estimated sleep efficiency and sleep ODI.</p><p><strong>Conclusion: </strong>High-resolution oximeter plus actigraphy combined with a cloud-based algorithm demonstrated adequate feasibility and applicability for OSA detection in children with craniofacial anomalies.</p>","PeriodicalId":21848,"journal":{"name":"Sleep Science","volume":"18 3","pages":"e253-e261"},"PeriodicalIF":1.8,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12460014/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145150629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unlocking Mysteries: Exploring the Dynamic Interplay Among Sleep, the Immune System, and Curcumin in Contemporary Research.","authors":"Rohit Kumar, Atul Pandey, Arpana Vibhuti, Manzoor Ali, Chung-Ming Chang, Ramendra Pati Pandey","doi":"10.1055/s-0045-1802321","DOIUrl":"10.1055/s-0045-1802321","url":null,"abstract":"<p><p>The scientific disciplines encompassing sleep, the immune system, and curcumin have garnered considerable interest due to their interconnectedness and potential implications for human health. Sleep is a crucial factor in maintaining optimal immune function, as it facilitates the release of cytokines, which are signaling molecules responsible for regulating immune responses. On the contrary, sleep deprivation has the potential of inhibiting immune function, thereby heightening the susceptibility to infection and disease. Curcumin, a naturally occurring polyphenol derived from the turmeric plant, has been observed to possess immunomodulatory characteristics through its ability to modulate the equilibrium between pro- and anti-inflammatory cytokines. It is worth noting that there is evidence suggesting that curcumin supplementation could enhance the quality of sleep. Scientific studies have indicated that curcumin supplementation has been associated with an increase in the duration of sleep and a decrease in wakefulness among individuals who are in good health. Additionally, curcumin supplementation has been found to enhance sleep quality and alleviate symptoms of depression in individuals diagnosed with major depressive disorder. The intricate interplay among sleep, the immune system, and curcumin is multifaceted, and scientific investigations indicate that curcumin may serve as a beneficial dietary adjunct to enhance immune function and optimize sleep quality. Nevertheless, additional investigation is required to fully comprehend the mechanisms through which curcumin alters the immune system and enhances sleep, as well as to ascertain the most effective dose and timing of curcumin supplementation.</p>","PeriodicalId":21848,"journal":{"name":"Sleep Science","volume":"18 3","pages":"e336-e346"},"PeriodicalIF":1.8,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12440604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145081613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parkinson's Disease Sleep Scale-2: The Brazilian Version's Cross-Cultural Adaptation and Validation.","authors":"Rogério José de Souza, Amanda Dos Santos Siqueira, Luísa Vigiani Cassiano, Tais Caroline Oliveira da Silva, Suhaila Mahmoud Smaili","doi":"10.1055/s-0044-1791977","DOIUrl":"10.1055/s-0044-1791977","url":null,"abstract":"<p><p><b>Objective</b>  To translate, cross-culturally adapt, and validate the Brazilian version of the Parkinson's Disease Sleep Scale-2 (PDSS-2/BR). <b>Methods</b>  This cross-sectional study addressed 80 patients with PD, and it was organized into two phases: 1) Translation and cross-cultural adaptation, which included 30 individuals in the scale's pretest stage and 2) Validation, when 50 individuals were assessed by the PDSS-2/BR, Pittsburgh Sleep Quality Index (PSQI), Parkinson's Disease Questionnaire-39 (PDQ-39), MDS-Unified Parkinson's Disease Rating Scale (MDS-UPDRS), and Hoehn and Yahr rating scale (HY); the PDSS-2/BR was retested 7 days later. The significance level was set at 5%. <b>Results</b>  The participants rated the PDSS-2/BR as having more than 90% comprehension. It also showed good reliability (Cronbach's alpha = 0.782) and excellent test-retest reliability (ICC _interrater  = 0.901; <i>p</i>  = 0.570; ICC _intrarater  = 0.905; <i>p</i>  = 0.116). Additionally, the scale showed good precision, with low standard error of measurement (SEM _inter  = 1.040; SEM _intra  = 0.908), and moderate to strong correlation with the PSQI, MDS-UPDRS, and PDQ-39 scales (rho = 0.46-0.74); only the HY scale showed no correlation. <b>Discussion</b>  The PDSS-2/BR is a reliable, precise, and valid instrument for evaluating sleep among Brazilian individuals with PD. Hence, it is expected to help researchers and clinicians improve the investigation of these symptoms, promoting early and assertive diagnoses and guiding the treatment and clinical management of this population.</p>","PeriodicalId":21848,"journal":{"name":"Sleep Science","volume":"18 2","pages":"e182-e189"},"PeriodicalIF":1.0,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12263210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144650590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}