Sexually transmitted diseases最新文献

{"title":"HPV-related cancer prevention among people experiencing housing instability: A systematic review.","authors":"Annalynn M Galvin, Idara N Akpan, Ashvita Garg, Paula M Cuccaro, Erika L Thompson, Diane M Santa Maria","doi":"10.1097/OLQ.0000000000002159","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002159","url":null,"abstract":"<p><strong>Background: </strong>HPV-related cancer is highly preventable through HPV vaccination and cancer screening, but people experiencing homelessness or housing instability (PEH) may not engage in these behaviors due to conflicting priorities. This systematic review synthesized and estimated HPV-related cancer prevention behaviors among PEH.</p><p><strong>Methods: </strong>Using PRISMA guidelines, articles published before 2023 were located via PubMed, Ovid/Medline, CINAHL, and Embase. Full-text, peer-reviewed studies that measured HPV-related cancer prevention in any sample of people experiencing homelessness were included. Two researchers abstracted data independently, with high interrater reliability (>90%). Results were narratively summarized with consensus, and proportions were compared using preventive behavior.</p><p><strong>Results: </strong>After reviewing 405 articles, we included 18 articles from the U.S. from 1998-2022. There were 6,674 people (e.g., women, youth, men who have sex with men) experiencing homelessness assessed for HPV-related cancer prevention behaviors. Pooled prevalence was approximately 59.8% (±6%) for cervical cancer screening in the last 3 years and 42.9% (±4.7%) for HPV vaccination initiation. Other factors related to housing instability and HPV-related cancer prevention included gender, sexual trauma, and procedural pain, with mixed results for housing status and HPV knowledge.</p><p><strong>Conclusions: </strong>Findings demonstrate the varied adherence to HPV-related cancer prevention, with rates consistently below recommended World Health Organization guidelines. Future studies should adjust for specific risk factors in modeling that may be associated with or modified by the effects of homelessness and evaluate upstream prevention (e.g., vaccination) and other types of HPV-related cancer (e.g., anal cancer).</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is single dose benzathine penicillin G adequate for late latent syphilis?","authors":"Noah Kojima, Peters Remco, Klausner D Jeffrey","doi":"10.1097/OLQ.0000000000002161","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002161","url":null,"abstract":"","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Economic Outcomes of Disease Intervention Specialist-Delivered Interventions for Sexually Transmitted Infections: A Systematic Review.","authors":"Erika G Martin, Arzana Myderrizi, Heeun Kim, Thomas L Gift, Angela B Hutchinson, Enrique M Saldarriaga, Harrell W Chesson","doi":"10.1097/OLQ.0000000000002160","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002160","url":null,"abstract":"<p><strong>Background: </strong>Although numerous studies have demonstrated the effectiveness of interventions delivered by disease intervention specialists (DIS), relatively few studies have assessed their economic outcomes. We performed a systematic literature review of the cost, cost-effectiveness, and cost-benefit of DIS-delivered interventions for sexually transmitted infections (STIs) in the United States.</p><p><strong>Methods: </strong>Building on a recent systematic review of the effectiveness of DIS-delivered interventions, we reviewed economic outcomes associated with these interventions for STIs. We searched articles indexed in MEDLINE, Web of Science, CINAHL, and ProQuest from 2000 through December 2022, using these inclusion criteria: addressed an intervention of DIS-delivered interventions for STIs including partner services; United States setting; and included estimates for program cost, cost-effectiveness, or cost-benefit. Findings were summarized through narrative synthesis.</p><p><strong>Results: </strong>Seven studies met the inclusion criteria. Overall, DIS-delivered interventions including STI partner services can be a cost-effective use of public health resources. In some scenarios, the cost of these interventions can be completely offset by averted medical costs. Cost and cost-effectiveness estimates of DIS-delivered interventions can vary across geographic settings and under different epidemiologic conditions.</p><p><strong>Conclusions: </strong>Although scarce, the available evidence suggests DIS-delivered interventions including STI partner services are an efficient use of public health resources. Health economic modeling studies are needed to facilitate conversion of intermediate cost-effectiveness outcomes (e.g., cost per syphilis case identified and treated) into standard cost-effectiveness outcomes (e.g., cost per quality-adjusted life year [QALY] gained).</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patterns of Congenital Syphilis in a Large Public Hospital: Birthing Parent Risk Factors and Infant Outcomes.","authors":"Diana D Villarreal, Katherine A Lewis, Mikhaela Cielo, Jeffrey D Klausner","doi":"10.1097/OLQ.0000000000002162","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002162","url":null,"abstract":"<p><strong>Background: </strong>Congenital syphilis (CS) in the United States increased 10-fold in the last decade. At a large public hospital in Los Angeles, the numbers of infants born to birthing parents with untreated syphilis during pregnancy have continued to rise.</p><p><strong>Methods: </strong>We compiled a retrospective case-series from all infant rapid plasma reagin (RPR) test results from 2022-2023 summarizing CS diagnosis and relevant diagnostic criteria. Chi-squared and Fisher's exact tests were used to examine associations between birthing parent risk factors and CS diagnosis.</p><p><strong>Results: </strong>Birthing parent syphilis complicated 97 out of 2367 live births (4.1%) at our institution. Approximately 36% (n = 35) of infants born to birthing parents with a history of syphilis (n = 94) were born to a birthing parent with inadequately treated syphilis or concern for reinfection. Infants with exposure to birthing parent syphilis were mostly asymptomatic at birth but had a high frequency of abnormalities in laboratory and radiographic evaluation. Compared to infants with Less Likely or Unlikely CS, birthing parents with infants with Highly Probable or Possible CS were more likely to have methamphetamine use during pregnancy (41% vs. 69%, p = 0.02), cocaine use during pregnancy (2% vs. 14%, p = 0.03), opiate use during pregnancy (7% vs. 37%, p = <0.001), and no prenatal care (7% vs. 40%, p ≤ 0.001).</p><p><strong>Conclusions: </strong>This case series identified birthing parent substance use and no prenatal care as risk factors for Highly Probable or Possible CS, underscoring the vulnerability of this population and informing future work in prevention of this disease.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Routine Pharyngeal Gonorrhea Test-of-Cure: Is It An Effective Cephalosporin-Resistant Gonorrhea Control Strategy?","authors":"Laura A S Quilter, Rebekah Horowitz, Kellie Hall, Cortni Bardier, Jonathan Bell, Annika A Bergstrom, Jason Beverley, Stephanie E Cohen, Megan Coleman, Stephanie Devlin, Rachel Harold, Meya Harris, Kevin Kamis, Renuka Khurana, Robert Kohn, Christie Mettenbrink, Masayo Nishiyama, Madeline Sankaran, Benjamin Takai, Corinne Velasquez, Karen A Wendel, Laura H Bachmann, Lindley Barbee","doi":"10.1097/OLQ.0000000000002157","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002157","url":null,"abstract":"<p><strong>Background: </strong>Centers for Disease Control and Prevention recommends test-of-cure (TOC) for persons with pharyngeal gonorrhea (GC) 7-14 days after treatment. We investigated the yield and feasibility of routine pharyngeal GC TOC to detect treatment failures.</p><p><strong>Methods: </strong>During May 2021-July 2022, four U.S. STD clinics implemented pharyngeal GC TOC. Sites collected demographic, clinical, and behavioral data on all treated pharyngeal GC and positive TOC cases. Cases were dispositioned with the suspected reason for positive TOC. To assess perceived feasibility, sites participated in qualitative interviews.</p><p><strong>Results: </strong>During the study period, 1,968 pharyngeal GC infections were diagnosed. Among 1,829 treated cases, 97.3% (n = 1,777) received ceftriaxone and 45.7% (n = 836) returned for TOC, varying by site (range: 35.5%- 70.8%). Among those with TOC, 4.7% (n = 39) were positive by NAAT. Of these, 48.7% had culture attempted; six positive TOC (15.4%) were also positive by culture. Most positive TOC (66.7%) were attributed to re-infection (n = 13) or false-positive results (n = 13). Six (15.4%) were treatment failures. Four failed recommended treatment and had a positive culture: two were susceptible to ceftriaxone and two did not have antimicrobial susceptibility results. Seven positive TOC (17.9%) had insufficient data to disposition. Sites perceived TOC to be feasible, though substantial resources were required.ConclusionRoutine pharyngeal GC TOC yielded 5% positivity, though treatment failure was rare (<1%), and no cases of cephalosporin-resistant GC were identified. Low TOC return rates, limited culture collection, and limited culture yield highlight challenges to determining the cause of a positive TOC and the limitations of TOC in identifying cephalosporin resistance.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Staffing and Budget Levels at Local STD Programs by County-Level Sociodemographic Characteristics During COVID-19.","authors":"Carolyn Luk, Kartika Palar, Jennifer Ludovic, Ryan Cramer, Thomas L Gift, Rebekah Horowitz, Jami S Leichliter","doi":"10.1097/OLQ.0000000000002152","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002152","url":null,"abstract":"<p><strong>Abstract: </strong>We examined the relationship between Local Health Department STD program staffing and budget changes and county-level sociodemographic characteristics. We found two population-level sociodemographic characteristics associated with STD budget cuts. Although staffing cuts were observed, none of the sociodemographic characteristics examined were associated with STD staffing cuts.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlates of using antibiotics to prevent sexually transmitted infections among cisgender sexual minority men and transgender women.","authors":"Drew A Westmoreland, Jacob Bleasdale, Alexa B D'Angelo, Rifa Ehsan, Viraj V Patel, Robert L Cook, Adam W Carrico, Christian Grov","doi":"10.1097/OLQ.0000000000002151","DOIUrl":"10.1097/OLQ.0000000000002151","url":null,"abstract":"<p><strong>Abstract: </strong>Prophylactic antibiotics are effective prevention strategies for STIs. This analysis explored preventative antibiotic use among cisgender sexual minority men and transgender women. Data were collected from August 2022-July 2023. Fourteen percent of participants reported use. Participants from communities most impacted by STIs had higher odds of reporting use.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"STI clinic visits and Chlamydia/Gonorrhea testing have not returned to pre-COVID levels, five U.S. jurisdictions, 2018-2022.","authors":"Jill C Diesel, Anna Cope, River Pugsley, Bryce Furness, Mohammad Rahman, James B Kent, Ashleigh Dunworth, Gayoung Lee, Nicole L Davis","doi":"10.1097/OLQ.0000000000002150","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002150","url":null,"abstract":"<p><strong>Abstract: </strong>We evaluated whether sexually transmitted infection (STI) clinic visits and chlamydia/gonorrhea tests in five jurisdictions had returned to pre-COVID levels by 2022. Patient volume and chlamydia/gonorrhea testing have not returned to pre-COVID levels, especially among people <30 years.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To whom will you send automated confidential SMS invitations to test for HIV? Results from an acceptability pilot study in northern Tanzania.","authors":"Salome-Joelle Gass, Jan Ostermann, Bernard Njau, Marco van Zwetselaar, Melkiory Beti, Thespina Yamanis, Leah McClimans, Rose Mwangi, Vaileth John, Tara Mtuy, Amy Hobbie, Nathan Thielman","doi":"10.1097/OLQ.0000000000002153","DOIUrl":"10.1097/OLQ.0000000000002153","url":null,"abstract":"<p><strong>Abstract: </strong>The Confidential Social Network Referrals for HIV Testing (CONSORT) intervention leverages the ubiquity of mobile phones and social networks to nudge at-risk populations to test for HIV. Pilot results suggest that confidential SMS testing invitations are acceptable among diverse populations and may reach those at above-average risk of HIV infection.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low Knowledge, Awareness, and Availability of Sexual Health Services: An Assessment of a Diverse North Dallas Community.","authors":"Drew A Beckman, Edgar Gonzalez, Bendu Coleman, Jeremy Y Chow","doi":"10.1097/OLQ.0000000000002149","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002149","url":null,"abstract":"<p><strong>Background: </strong>STI and HIV rates have been growing nationwide without adequate resources for treatment and prevention. Barriers to access need to be identified and rectified in order to reach affected populations.</p><p><strong>Methods: </strong>An exploratory community assessment using a purposive sample in an underserved community in Dallas, TX was conducted to gain insight into perceptions of existing access, barriers, and cultural norms in addition to preferences for sexual health services in the area (n = 100). Results were compiled using descriptive statistics.</p><p><strong>Results: </strong>Our respondents came from priority populations with high HIV/STI prevalence including Black individuals, Latinx individuals, and MSM. Most participants said they would feel comfortable accessing sexual health services in a medical building (95%), mobile clinic (91%), office building (76%), or pharmacy (74%). Half preferred a closer clinic compared to 2% who preferred farther away. Wide lack of awareness of sexual health services was cited as the primary barrier by 57%. Participants were most interested in having STI (92%) and HIV (91%) testing/treatment offered with very few expressing interest in PrEP (24%), nPEP (4%), or DoxyPEP (3%) suggesting low knowledge about these options. Further, Black individuals felt more comfortable than Latinx individuals when discussing sexual health with peers/friends, sex partners, and healthcare providers.</p><p><strong>Conclusions: </strong>Many ethnic and sexual minorities disproportionately affected by these epidemics lack access to sexual health services in their communities. Local community assessments like this can serve as a model for others seeking to expand sexual health services to address the growing HIV and STI syndemics.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}