Sexually transmitted diseases最新文献

{"title":"The Missing Link: Hepatitis C Linkage to Care Through a Public Sexual Health Clinic.","authors":"Amirtha Dileepan, Lucy Alderton, Oluyomi Obafemi, Sarah E Rowan, Karen A Wendel","doi":"10.1097/OLQ.0000000000002114","DOIUrl":"10.1097/OLQ.0000000000002114","url":null,"abstract":"<p><strong>Abstract: </strong>This study evaluates hepatitis C testing and referral for treatment among patients attending a public sexual health clinic. In patients with hepatitis C infection, progression from linkage to care to sustained virologic response was low. Innovative approaches are needed to optimally integrate hepatitis C care in sexual health clinics.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"e68-e70"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142847700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unsettling Surge in Multidrug-Resistant and Extensively Drug-Resistant Neisseria gonorrhoeae : Insights From a National Reference Centre for Sexually Transmitted Infections in India.","authors":"Devanshi Sharma, Sumathi Muralidhar, Naveen Chandra Joshi, Ruchi Singh","doi":"10.1097/OLQ.0000000000002194","DOIUrl":"10.1097/OLQ.0000000000002194","url":null,"abstract":"<p><strong>Background: </strong>The rapidly evolving drug resistance of Neisseria gonorrhoeae to various drugs used in its treatment has posed significant challenges, especially in developing countries. A rise in cephalosporin minimum inhibitory concentrations (MIC) among N. gonorrhoeae was identified in parts of Asia, as early as the late 1990s. Drugs such as penicillin, tetracycline, and ciprofloxacin, which were effective in the past, are now almost never used in treating gonorrhea. This research aimed to study the resistance trends of N. gonorrhoeae over a temporal span of 5 years.</p><p><strong>Methods: </strong>For 5 years, samples from STI clinic attendees were collected and processed for isolating N. gonorrhoeae . Confirmed isolates were subjected to antimicrobial susceptibility tests using the MIC E-strip method.</p><p><strong>Results: </strong>A total of 231 isolates of N. gonorrhoeae were studied, with 97.5% from male patients. Decreased susceptibility to third-generation cephalosporins (cefixime and ceftriaxone) was 6.06%. Azithromycin resistance was reported in 13.4% of isolates, with three-fourths from the states of North India (Delhi and Chandigarh). Of these isolates, 22.5% showed high-level resistance to azithromycin. In addition, 16 isolates were multidrug-resistant, and 1 isolate was an extensively drug-resistant N. gonorrhoeae.</p><p><strong>Conclusions: </strong>These findings highlight the urgent need for concerted efforts to address the burgeoning threat of antimicrobial resistance (AMR) in N. gonorrhoeae . Continued surveillance of drug resistance is crucial. Efforts should be made to explore novel, effective treatment options to resolve this issue.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"603-608"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of Amsel-Defined Bacterial Vaginosis Before and After Transvaginal Ultrasound With Lubricant Application.","authors":"Sarah E Brown, Xin He, Laurence Magder, Christina A Stennett, Sarah J Robbins, Daniel Morgan, Elizabeth Johnston, Jacques Ravel, Katrina Mark, Khalil G Ghanem, Rebecca M Brotman","doi":"10.1097/OLQ.0000000000002158","DOIUrl":"10.1097/OLQ.0000000000002158","url":null,"abstract":"<p><strong>Abstract: </strong>Emerging evidence suggests a link between hyperosmolal vaginal lubricants and bacterial vaginosis. In 80 patients undergoing transvaginal ultrasound with a standardized lubricant, we observed a significant increase in Amsel-defined bacterial vaginosis 1 to 13 days after transvaginal ultrasound compared with baseline, likely driven by heightened amine odor (odds ratio, 5.88; 95% confidence interval, 1.22-28.23).</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"e71-e73"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12278607/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Facilitators and Barriers to the Rollout of Doxycycline Postexposure Prophylaxis for Sexually Transmitted Infections in a Boston Community Health Center.","authors":"Lao-Tzu Allan-Blitz, Michael Traeger, Sy Gitin, Kevin Smith, Kenneth H Mayer, Taimur Khan","doi":"10.1097/OLQ.0000000000002190","DOIUrl":"10.1097/OLQ.0000000000002190","url":null,"abstract":"<p><strong>Background: </strong>Doxycycline postexposure prophylaxis (doxyPEP) is a promising strategy to prevent bacterial sexually transmitted infections. Limited data exist evaluating patient and provider experiences since doxyPEP has become widely available. We aimed to explore such factors among providers and patients during real-world implementation within one community health center.</p><p><strong>Methods: </strong>Doxycycline postexposure prophylaxis was rolled out at Fenway Health on February 2, 2023. To support rollout, electronic health record tools, 3 provider training sessions, and a community town hall were developed and implemented. All providers who participated in doxyPEP trainings were surveyed as well as patients with evidence of a doxyPEP discussion during a clinic encounter who were retrospectively identified via chart review.</p><p><strong>Results: </strong>Between rollout and September 3, 2024, there were 3770 doxyPEP prescriptions. Among 45 providers, the median score of comfort having conversations about doxyPEP increased from 78 (interquartile range, 52-100) out of 100 after the second training to 100 (interquartile range, 88-100) after the third training. Of 150 patient responses, 90 (60.0%) were from individuals prescribed doxyPEP; reasons for use included sex with a random partner (65.6%) and condomless anal intercourse (63.3%). Among 60 patients not prescribed doxyPEP, 25 (41.7%) reported they did not feel it was warranted due to low perceived risk. Eleven (18.3%) reported they felt the risks outweighed the benefits.</p><p><strong>Conclusion: </strong>Without national guidelines, the uptake of doxyPEP was robust, supported by electronic support tools and provider training sessions for clinicians, as well as community engagement efforts. Differences in risk perception were important factors in the choice to use doxyPEP.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"585-590"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209540","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minority Stress and Intimate Violence Perpetration Among Men Who Have Sex With Men in China: Hazardous Alcohol Use as a Meditator.","authors":"Guohui Yang, Xinjing Liu, Jiayan Li, Jing He, Xiaoni Zhong","doi":"10.1097/OLQ.0000000000002189","DOIUrl":"10.1097/OLQ.0000000000002189","url":null,"abstract":"<p><strong>Background: </strong>Intimate partner violence (IPV) has become a global public health issue, including in men who have sex with men (MSM). This study, based on minority stress theory, examines the relationship between minority stress and IPV perpetration among Chinese MSM, emphasizing the role of hazardous alcohol use. We propose 3 hypotheses: (1) enacted stigma, internalized stigma, identity concealment, and hazardous alcohol use contribute to IPV perpetration; (2) hazardous alcohol use mediates the effect of minority stress on IPV perpetration; and (3) proximal stressors (internalized stigma and identity concealment) serve as mediators between enacted stigma and IPV perpetration.</p><p><strong>Methods: </strong>A total of 915 valid questionnaires were collected in China via snowball sampling for analysis, using structural equation modeling to examine the relationships between variables.</p><p><strong>Results: </strong>Among 915 MSM, the IPV perpetration prevalence was 18.6% in the past year. The structural equation model showed that enacted stigma ( β = 0.414, P < 0.001), internalized stigma ( β = 0.179, P < 0.01), and hazardous alcohol use ( β = 0.245, P < 0.001) significantly contributed to IPV perpetration. Although identity concealment ( β = -0.134, P < 0.01) had a protective effect. Hazardous alcohol use mediated the relationship between minority stress and IPV perpetration, except for internalized stigma. Proximal stressors also partially mediated the link between enacted stigma and IPV perpetration.</p><p><strong>Conclusions: </strong>Findings suggest that enacted stigma, internalized stigma, identity concealment, and hazardous alcohol use are associated with IPV perpetration. Reducing stigma toward MSM and addressing hazardous alcohol use are crucial for IPV perpetration.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"618-624"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Human Papillomavirus in the Neovagina of Transgender Women in Thailand: Prevalence, Diversity, and Associated Risk Factors.","authors":"Amaraporn Rerkasem, Myo Zin Oo, Natnita Mattawanon, Supachai Sakkhachornphop, Sumalee Siriaunkgul, Thanadul Jakkaew, Kittipan Rerkasem, M Kumi Smith","doi":"10.1097/OLQ.0000000000002196","DOIUrl":"10.1097/OLQ.0000000000002196","url":null,"abstract":"<p><strong>Background: </strong>Transgender women (TGW) face unique sexual health challenges, including neovagina complications, with limited research on sexually transmitted disease prevalence and risk factors. This study aimed to investigate the prevalence, genotype diversity, and associated risk factors of human papillomavirus (HPV) infection in the neovagina of TGW in Thailand. Cisgender women (CGW) are included to provide contextual insights.</p><p><strong>Methods: </strong>We conducted a cross-sectional study from April to October 2023, recruiting 63 TGW from gender care clinics and community health centers, and 25 CGW from routine gynecological checkups. Samples were collected via Papanicolaou test from the neovagina of TGW and the cervix of CGW for HPV testing. Participants completed questionnaires on sociodemographic characteristics, sexual behaviors, and health-related factors. Univariate Poisson regression was used to explore associations with HPV infection.</p><p><strong>Results: </strong>Among TGW, 66.7% had any HPV type, with 41.3% being high-risk and 36.5% having multiple infections. In CGW, 24% had any HPV type and 20% had high-risk HPV. About 34.9% of TGW had 9-valent HPV vaccine-preventable types. Inconsistent condom use and syphilis exposure were associated with a higher risk of any HPV infection (risk ratio [RR] of 1.59 [95% confidence interval {CI}, 1.07-2.35] and RR of 1.57 [95% CI, 1.29-1.90]) and lack of awareness linked to high-risk infection (RR, 1.84 [95% CI, 1.04-3.24]) among TGW. Conversely, CGW showed vaginal and pelvic symptoms as the only risk factor.</p><p><strong>Conclusion: </strong>This novel study of HPV prevalence in TGW neovaginas reveals a high burden of both high- and low-risk types, underscoring the urgent need for tailored prevention, education, vaccination, and screening.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"641-648"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Syphilis in Pregnant Women and Congenital Syphilis in Japan, 2022 to 2023: A Warning for Other Countries.","authors":"Ayu Kasamatsu, Takuri Takahashi, Yuzo Arima, Hanae Ito, Maki Masutani, Shimpei Murai, Natsuko Nakamura, Ayano Orime, Masami Kitaoka, Yukihiro Akeda, Motoi Suzuki, Takuya Yamagishi","doi":"10.1097/OLQ.0000000000002173","DOIUrl":"10.1097/OLQ.0000000000002173","url":null,"abstract":"<p><strong>Abstract: </strong>After a brief decline, syphilis case counts among pregnant women reported through Japan's national surveillance doubled from 2021 to 2023; congenital syphilis case counts/100,000 live births also doubled to >5. The unprecedented trends in Japan highlight the current heterosexual syphilis epidemic's relentlessness, with important implications for other countries.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"e65-e67"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posttraumatic Stress Disorder and Its Associations With Sexually Transmitted Infections Among Veterans.","authors":"Kartavya J Vyas, Vincent C Marconi, Brian K Agan, Patrick S Sullivan, Jodie L Guest","doi":"10.1097/OLQ.0000000000002193","DOIUrl":"10.1097/OLQ.0000000000002193","url":null,"abstract":"<p><strong>Background: </strong>One-quarter of all veterans who deployed to Iraq and Afghanistan post-9/11 developed posttraumatic stress disorder (PTSD). No known longitudinal study has examined the associations between PTSD and sexually transmitted infections (STIs). Objectives were to (1) examine trends in incidences of PTSD and STIs, (2) estimate the associations between individually measured assessments of PTSD and STI incidence, (3) measure effect modification by deployments and combat exposure, and (4) explore time-varying associations.</p><p><strong>Methods: </strong>In this prospective cohort study of all veterans who deployed to Iraq and Afghanistan in 2001 to 2022 and receive care in the Department of Veterans Affairs (n = 1,570,654), patients contributed a total of 15,535,454 person-years of follow-up. Joinpoint regression models, marginal structural Poisson models, and marginal structural shared frailty models were fitted with a time-dependent exposure, adjusted for time-independent and time-dependent confounding and informative censoring.</p><p><strong>Results: </strong>Incidences in PTSD, hepatitis C virus, and human papillomavirus significantly decreased, but those of chlamydia, human immunodeficiency virus, and syphilis significantly increased. Posttraumatic stress disorder was associated with increased rates (adjusted rate ratio, 95% confidence interval) of HPV by 3% (1.03 [1.00-1.05]), human immunodeficiency virus by 8% (1.08 [1.02-1.15]), hepatitis B virus by 9% (1.09 [1.01-1.18]), genital HSV by 9% (1.09 [1.07-1.11]), syphilis by 11% (1.11 [1.05-1.17]), chlamydia by 20% (1.20 [1.17-1.24]), gonorrhea by 21% (1.21 [1.13-1.31]), and hepatitis C virus by 69% (1.69 [1.62, 1.77]), and remained statistically significant.</p><p><strong>Discussion: </strong>Posttraumatic stress disorder was associated with increased rates of all STIs, and these associations did not diminish with time. Results may help guide preventive efforts and medical decisions for those with PTSD.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"609-617"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144200020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacterial Vaginosis Incidence Following a Single Hyperosmolal Vaginal Lubricant Exposure: A Comparison of Two Observational Cohorts.","authors":"Sarah E Brown, Xin He, Laurence Magder, Elizabeth D Johnston, Daniel Morgan, Jacques Ravel, Katrina Mark, Khalil G Ghanem, Rebecca M Brotman","doi":"10.1097/OLQ.0000000000002184","DOIUrl":"10.1097/OLQ.0000000000002184","url":null,"abstract":"<p><strong>Background: </strong>Hyperosmolal lubricants may negatively affect the vaginal microenvironment, increasing the risk for bacterial vaginosis (BV). We compared the incidence of Amsel-defined BV in reproductive-age women exposed to hyperosmolal lubricant during transvaginal ultrasound to those without recent lubricant exposure.</p><p><strong>Methods: </strong>We analyzed 2 observational cohorts over 10 weeks: 58 lubricant-exposed women from the Gynecology and Lubricants Effects study and 59 lubricant-unexposed women from a University of Alabama Birmingham cohort linked to the University of Maryland Human Microbiome Project. Bacterial vaginosis was diagnosed using Amsel criteria at baseline, mid-study (lubricant-exposed, week 2; lubricant-unexposed, week 5), and final visit (week 10), and categorized by symptomatology. Risks for incident BV and Amsel criteria were assessed using modified Poisson regression with robust standard errors. An additional outcome of new-onset/newly symptomatic BV included those with baseline asymptomatic BV. A secondary analysis focused on Black participants (N = 73) due to an observed higher BV incidence.</p><p><strong>Results: </strong>Baseline demographics and behaviors were similar between the cohorts. Among all participants, lubricant was not associated with new-onset BV (adjusted relative risk [aRR], 1.32; 95% confidence interval [CI], 0.58-3.01). Eighty-eight percent (23/26) of all new-onset/newly symptomatic BV cases occurred in Black participants. Among Black participants, exposure to lubricant doubled the risk of developing new-onset BV (aRR, 2.18; 95% CI, 1.16-4.11) and new-onset/newly symptomatic BV (aRR, 1.91; 95% CI, 1.04-3.51), and increased the risk for new-onset clue cells (aRR, 2.18; 95% CI, 1.17-4.06) versus no lubricant exposure.</p><p><strong>Conclusion: </strong>Hyperosmolal lubricants was associated with BV incidence in Black women. Factors contributing to this elevated risk require further research.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"625-630"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12278670/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144143269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intentions of Telehealth Appointments and Associations Between Barriers and Likelihood of Telehealth Appointments Among Clients at Chicago Department of Public Health Sexually Transmitted Infection Specialty Clinics.","authors":"Casey Morgan Luc, Michael Wasz, Grace Kadubek, Van Quach, Colleen M Leonard, David Kern, Tammy Rutledge, Irina Tabidze, Supriya D Mehta","doi":"10.1097/OLQ.0000000000002188","DOIUrl":"10.1097/OLQ.0000000000002188","url":null,"abstract":"<p><strong>Background: </strong>With the COVID-19 pandemic, telehealth services emerged as an effective care-delivery tool to increase equitable access to care. The Chicago Department of Public Health's (CDPH) sexually transmitted infections (STI) specialty clinics provide comprehensive, no-cost care for STIs and HIV. Telehealth services may facilitate expanded services, but the acceptability to patients is unknown.</p><p><strong>Methods: </strong>We analyzed data collected from participants seeking care at one of 2 CDPH STI specialty clinics from July 6 to September 12, 2023. Modified Poisson regression was used to assess factors associated with (1) using any telehealth services in the past 12 months, and (2) likelihood of not using future telehealth services at STI specialty clinics.</p><p><strong>Results: </strong>Of 251 respondents, most were 18-29 years old (56%), 36% non-Hispanic (NH) White, 28% NH Black, and 71% male. Nearly half (46%) had used past telehealth services and 33% reported being unlikely to use telehealth services at specialty clinics. In adjusted analyses, compared with NH White, NH Black participants were more likely to report no intention to use future telehealth services (adjusted prevalence ratio, 1.55; 95% confidence interval, 1.02-2.35). Among those who did not previously use telehealth services, choosing CDPH STI specialty clinics for privacy concerns/confidentiality was significantly associated with a lower likelihood of using future telehealth services.</p><p><strong>Conclusions: </strong>A reported moderate-high acceptance of telehealth services at CDPH STI specialty clinics may suggest telehealth implementation could have successful uptake. Next steps toward implementing a telehealth program will need to consider which services to include, provider training and needs, and system factors, such as integration with electronic medical records and establishment of a patient portal.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"591-596"},"PeriodicalIF":1.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144162373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}