Sexually transmitted diseases最新文献

Implementing a 24/7 Congenital Syphilis Hotline for California Clinicians: Results from a 13-week Pilot Project. 为加州临床医生实施24/7先天性梅毒热线：为期13周的试点项目的结果。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-04-03 DOI: 10.1097/OLQ.0000000000002163

Helen Burnside, Destiny Kelley, Ina U Park, Hilary Reno, Karen Wendel, Mariska Osborne-Wells, Brea Ford, Alexandra Coor, Lindley A Barbee, Laura A S Quilter, Kelly A Johnson

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High Volume and High Positivity of Chlamydia and Gonorrhea Tests by Anatomic Site from a Large National Laboratory in the United States, 2019-2023. 2019-2023年美国大型国家实验室解剖现场衣原体和淋病检测的高容量和高阳性

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-04-03 DOI: 10.1097/OLQ.0000000000002165

Guoyu Tao, Thomas L Gift

{"title":"High Volume and High Positivity of Chlamydia and Gonorrhea Tests by Anatomic Site from a Large National Laboratory in the United States, 2019-2023.","authors":"Guoyu Tao, Thomas L Gift","doi":"10.1097/OLQ.0000000000002165","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002165","url":null,"abstract":"Background: Chlamydia and gonorrhea are among the most commonly reported sexually transmitted infections (STIs) in the U.S. Testing for chlamydia and gonorrhea infection can be conducted by anatomic site (site-specific). Monitoring testing volume and positivity by anatomic site is important.Methods: Using a large national laboratory dataset, we assessed chlamydia and gonorrhea test volume and positivity by anatomical site in patients aged 15-60 years.Results: The data contained 45 million tests each for chlamydia and gonorrhea for 2019-2023. Of chlamydia tests, 71.6% were for women. Among women, 0.4%, 1.5%, and 98.1% were performed on rectal, pharyngeal, and urogenital specimens; chlamydia positivity was 7.3%, 2.0%, and 4.3%, respectively. Among men, 10.5%, 13.7%, and 75.8% were performed on rectal, pharyngeal, and urogenital specimens; chlamydia positivity was 8.0%, 1.4%, and 6.3%, respectively. Among people aged 15-24 years, chlamydia positivity was 12.8% for rectal, 3.4% for pharyngeal, and 8.7% for urogenital among women, and 11.6%, 2.4%, and 12.2% among men, respectively. Gonorrhea testing volume overall and by age and sex was similar to that of chlamydia. Gonorrhea rectal, pharyngeal, and urogenital positivity was 3.2%, 2.4%, and 1.0% among women; 6.8%, 5.2%, and 3.3% among men; and 4.3%, 3.0%, and 1.6% among women aged 15-24 years, and 10.5%, 7.2%, and 4.6% among men aged 15-24 years, respectively.Conclusion: Although men accounted for <30% of overall chlamydia and gonorrhea testing, they accounted for a majority of extragenital testing. High rates of chlamydia and gonorrhea positivity by specimen type among many demographic groups, especially for extragenital specimens from men and young people, highlight the importance of STI prevention in the U.S.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Prevalence of Chlamydia trachomatis genital infection among sexually experienced females aged 14-24 years by race/ethnicity, United States: 2011-March 2020. 美国 14-24 岁有性经历女性中沙眼衣原体生殖器感染流行率（按种族/族裔分列）：2011 年至 2020 年 3 月。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-04-03 DOI: 10.1097/OLQ.0000000000002164

Casey E Copen, Ian H Spicknall, Patricia J Dittus, Kristen M Kreisel

{"title":"Prevalence of Chlamydia trachomatis genital infection among sexually experienced females aged 14-24 years by race/ethnicity, United States: 2011-March 2020.","authors":"Casey E Copen, Ian H Spicknall, Patricia J Dittus, Kristen M Kreisel","doi":"10.1097/OLQ.0000000000002164","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002164","url":null,"abstract":"Background: Since 2013, national trends in behavioral factors that increase STI risk among adolescent and young adult (A/YA) females have been mixed (e.g., fewer sex partners, lower condom use). We used data from a national sample of A/YA females to examine racial disparities in CT prevalence considering these trends.Methods: Using 2011-March 2020 National Health and Nutrition Examination Survey data, we estimated the prevalence, unadjusted and adjusted prevalence ratios (APRs) of a positive CT urine test among sexually experienced non-Hispanic Black (Black), Hispanic, non-Hispanic Other race (NHO), and non-Hispanic White (White) A/YA females. Percentages were categorized by race/ethnicity, and each compared to the average of the other race/ethnic groups (e.g., Black vs. Hispanic, NHO and White). Covariates included age group, health insurance coverage, number of sex partners and condom use (both past year).Results: Overall, the prevalence of CT infection among A/YA females was 5.8% (95% CI: 4.5%-7.3%). CT prevalence was higher among Black females (vs. Hispanic, NHO, and White) (11.7%; 95%CI: 8.7%-15.2%) and lower among White females (vs. Black, Hispanic, and NHO) (3.2%; 95%CI: 1.7%-5.5%). Compared with the average CT prevalence for Hispanic, NHO, and White females, Black females had a higher adjusted CT prevalence (APR: 2.48, 95%CI: 1.63-3.75).Conclusions: Nationally, CT prevalence was 2.5 times as high among Black A/YA females than the average prevalence for Hispanic, NHO, and White females. Inclusion of behavioral STI risk factors did not attenuate this association. Research incorporating sexual network-level factors associated with CT transmission may provide additional insights.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143773509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Preferences and Acceptability of Testing for Sexually Transmitted Infections in an HIV Pre-Exposure Prophylaxis Clinic in Hanoi, Vietnam. 越南河内HIV暴露前预防诊所性传播感染检测的偏好和可接受性。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-04-01 Epub Date: 2024-12-03 DOI: 10.1097/OLQ.0000000000002109

Hao T M Bui, Paul C Adamson, Thanh C Nguyen, Nguyen S Dau, Khanh D Nguyen, Loc Q Pham, Giang M Le, Jeffrey D Klausner

{"title":"Preferences and Acceptability of Testing for Sexually Transmitted Infections in an HIV Pre-Exposure Prophylaxis Clinic in Hanoi, Vietnam.","authors":"Hao T M Bui, Paul C Adamson, Thanh C Nguyen, Nguyen S Dau, Khanh D Nguyen, Loc Q Pham, Giang M Le, Jeffrey D Klausner","doi":"10.1097/OLQ.0000000000002109","DOIUrl":"10.1097/OLQ.0000000000002109","url":null,"abstract":"Background: Men who have sex with men using HIV Pre-Exposure Prophylaxis are a vulnerable population with a high prevalence of sexually transmitted infections (STIs). Self-collection of specimens could improve STI testing, yet implementation in low-resource settings is limited. The study aimed to assess the feasibility and acceptability of self-collection for STI testing and to understand STI testing preferences among Pre-Exposure Prophylaxis clients in Hanoi, Vietnam.Methods: From January to December 2022, men who have sex with men 16 years and older, participating in a clinic-based HIV PrEP program were enrolled. Participants self-collected pharyngeal, anal, and urine samples for Chlamydia trachomatis and Neisseria gonorrhoeae testing. Testing preferences were assessed through conjoint analysis using 8 hypothetical testing profiles across 5 testing attributes; each profile was rated on a Likert scale (0-5) to create an impact score. Differences between attributes were assessed using a 2-sided, 1-sample t test of the impact score.Results: There were 529 participants enrolled; all were male. Specimens from 3 sites were provided by 97.9% (518 of 529). Mean satisfaction with self-collection was 4.3 (SD, 1.0), 99.4% reported they would perform again. In conjoint analysis, cost (free vs. US $17) had the highest impact on testing preference (impact score: 25.2; P < 0.001). A 1-week time to test result notification was preferred to 90 minutes (impact score: -0.8; P = 0.03).Conclusions: We found high acceptability of self-collection for STI testing among HIV PrEP clients in Vietnam. Cost was the most important factor affecting testing uptake. Expanding self-collection and lowering costs could improve STI testing in HIV PrEP programs.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"242-247"},"PeriodicalIF":2.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11888897/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142772404","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mpox Vaccine Communication Among Sexually Active Men Who Have Sex With Men. 在性活跃的男男性行为者中传播麻风腮疫苗。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-04-01 Epub Date: 2024-12-14 DOI: 10.1097/OLQ.0000000000002117

Winston E Abara, Tom Carpino, Kaitlyn Atkins, Marissa Hannah, O Winslow Edwards, Kaytlin J Renfro, Stefan Baral, Travis Sanchez, Emily R Learner, Eboni Galloway, Amy Lansky

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Childhood Sexual Abuse, Alcohol Problem Scores, and Race Are Associated With Syphilis Incidence in a Prospective Cohort of Young Sexual and Gender Minority Adults Assigned Male at Birth. 在一个前瞻性队列中，性少数群体和性别少数群体的年轻成年人在出生时被指定为男性，他们的童年性虐待、酗酒问题得分和种族与梅毒发病率有关。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-04-01 Epub Date: 2024-12-16 DOI: 10.1097/OLQ.0000000000002120

Casey D Xavier Hall, Daniel T Ryan, Christina Hayford, Ethan Morgan, Richard D'Aquila, Brian Mustanski

{"title":"Childhood Sexual Abuse, Alcohol Problem Scores, and Race Are Associated With Syphilis Incidence in a Prospective Cohort of Young Sexual and Gender Minority Adults Assigned Male at Birth.","authors":"Casey D Xavier Hall, Daniel T Ryan, Christina Hayford, Ethan Morgan, Richard D'Aquila, Brian Mustanski","doi":"10.1097/OLQ.0000000000002120","DOIUrl":"10.1097/OLQ.0000000000002120","url":null,"abstract":"Background: Syphilis rates in the United States have dramatically increased in recent years and are high among young men who have sex with men and transgender women. However, few studies have examined a wide range of risk factors for syphilis incidence prospectively in young sexual and gender minority (YSGM) populations in the United States. One framework that may have utility in understanding syphilis risk factors is syndemics, which focuses on comorbid factors and their mutual influence. The current analysis examines demographic, comorbid health, and sociostructural risk factors for syphilis in YSGM assigned male at birth including applying a syndemic framework.Methods: Participants were part of a Chicago-based prospective cohort called RADAR (n = 738). All participants were YSGM. Syphilis cases were identified by serologic screening with a reverse-sequence testing algorithm. Risk factors included demographics, indicators of sexual risk, mental health, substance use, and violence victimization. Syndemic component score was calculated by adding the number of syndemic conditions. Analyses included multivariable logistic regressions.Results: In multivariable predictive modeling, Black identity, childhood sexual abuse, and alcohol problems predicted incident syphilis. Although roughly 37% of participants were indicated as having at least 2 syndemic conditions, the syndemic component did not predict syphilis incidence.Conclusions: Syphilis incidence is high in this sample of YSGM. Additional research is needed to better understand mechanisms driving associations between childhood sexual abuse and syphilis incidence as well as to develop interventions improve testing and treatment among Black YSGM, YSGM who experience childhood sexual abuse, and YSGM who experience alcohol problems.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"266-271"},"PeriodicalIF":2.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142839897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Efficacy of Doxycycline-Sitafloxacin Sequential Therapy for Urogenital Mycoplasma genitalium Infection in Nanjing, China. 多西环素-西他沙星序贯治疗南京泌尿生殖道支原体感染的疗效观察。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-04-01 Epub Date: 2024-11-21 DOI: 10.1097/OLQ.0000000000002105

Mengjin Yuan, Wenjing Le, Yuanyuan Zhao, Lu Gan, Sai Li, Xiaohong Su

{"title":"Efficacy of Doxycycline-Sitafloxacin Sequential Therapy for Urogenital Mycoplasma genitalium Infection in Nanjing, China.","authors":"Mengjin Yuan, Wenjing Le, Yuanyuan Zhao, Lu Gan, Sai Li, Xiaohong Su","doi":"10.1097/OLQ.0000000000002105","DOIUrl":"10.1097/OLQ.0000000000002105","url":null,"abstract":"Background: The aim of this study was to evaluate the efficacy of doxycycline-sitafloxacin sequential therapy in the treatment of Mycoplasma genitalium (Mg) urogenital infections in Nanjing, China.Methods: Potential subjects were tested initially for Mg infection by nucleic acid amplification testing and again at least 21 days after completion of doxycycline (100 mg twice daily for 7 days)-sitafloxacin (100 mg twice daily for 7 days) sequential therapy. The presence of macrolide and quinolone resistance-associated mutations in 23S rRNA, parC, gyrA, and gyrB genes in Mg was examined at baseline and upon retesting of specimens from subjects that did not clear Mg.Results: A total of 218 patients were screened for Mg, of whom 65 were positive for Mg; 63 Mg-infected patients were enrolled. Twenty-two (35%) Mg-infected subjects (16 heterosexual men, 5 women, and 1 man who had sex with men [MSM]) were successfully evaluated with a test of cure; 20 (91%) cleared Mg infection. In pretreatment specimens, mutations in 23S rRNA, parC (G248T [S83I]), gyrA (G277T [G93C]), and gyrB genes were present in 100% (19 of 19), 61.1% (11 of 18), 6.7% (1 of 15), and 7.1% (1 of 14), respectively. Mg clearance rates were 4 of 4 in infected subjects that possessed both wild-type parC and gyrA genes, and 9 of 10 when a parC G248T mutation and an otherwise wild-type gyrA gene were identified. Two subjects (9%) reported mild adverse events.Conclusions: Doxycycline-sitafloxacin sequential therapy was well tolerated and effective against most urogenital Mg infections in Nanjing and may provide an option for treatment.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":"52 4","pages":"259-265"},"PeriodicalIF":2.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11878589/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143573871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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Erratum: Absence of Lymphogranuloma Venereum Among Men Who Have Sex With Men With Rectal Chlamydia trachomatis Infections Within an HIV Preexposure Prophylaxis Program in Hanoi, Vietnam. 更正：在越南河内的HIV暴露前预防项目中，与直肠沙眼衣原体感染的男性发生性行为的男性中没有性病性淋巴肉芽肿。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-04-01 Epub Date: 2024-12-31 DOI: 10.1097/OLQ.0000000000002125

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Response to "Qualitatively Assessing ChatGPT Responses to Frequently Asked Questions Regarding Sexually Transmitted Diseases: Considerations". 对 "Qualitatively Assessing ChatGPT Responses to Frequently Asked Questions Regarding Sexually Transmitted Diseases：考虑因素"。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-04-01 Epub Date: 2024-12-16 DOI: 10.1097/OLQ.0000000000002121

Elijah Moothedan, Vama Jhumkhawala, Sara Burgoa, Lisa Martinez, Lea Sacca

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Commentary on the Benefits of In-Person Syphilis Partner Services for Priority Populations.

IF 2.4 4区医学