Sexually transmitted diseases最新文献

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Treatment variability among people assigned male at birth with repeat positive Mycoplasma genitalium tests: a case series. 生殖支原体检测重复阳性的男性出生时的治疗差异:一个病例系列。
IF 1.9 4区 医学
Sexually transmitted diseases Pub Date : 2026-10-13 DOI: 10.1097/OLQ.0000000000002424
Chase A Cannon, Timothy W Menza, Christina S Thibault, Gwendolyn E Wood, Lisa E Manhart
{"title":"Treatment variability among people assigned male at birth with repeat positive Mycoplasma genitalium tests: a case series.","authors":"Chase A Cannon, Timothy W Menza, Christina S Thibault, Gwendolyn E Wood, Lisa E Manhart","doi":"10.1097/OLQ.0000000000002424","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002424","url":null,"abstract":"<p><strong>Background: </strong>Mycoplasma genitalium (MG) can cause nongonococcal urethritis (NGU) and symptomatic proctitis. Rising antimicrobial resistance and lack of clinically available molecular resistance assays make MG treatment challenging. This study adds systematic data on the effectiveness of alternative MG regimens.</p><p><strong>Methods: </strong>Adult natal male patients who attended a public Sexual Health Clinic (SHC) and had ≥2 positive MG nucleic acid amplification tests within any 6-month period from January 2023-September 2025 were included. We classified cases as persistent infection or reinfection using clinical, demographic and self-reported behavioral data. For each patient, we summarized total number of visits, number, duration and components of each antibiotic regimen, and outcomes by MG clinical syndrome and infection status (persistence vs reinfection).</p><p><strong>Results: </strong>Among 3,009 SHC patients, 400 (13%) had incident MG and 19 (4.8%) met inclusion criteria for repeat MG infection across 61 clinic visits. Nongonococcal urethritis (n=14/19 patients, 74%) and proctitis (n=2/19 patients, 10%) were the most prevalent syndromes. Suspected reinfection was common (40%). All 19 patients achieved cure, including 10 (53%) with microbiologic and 9 (47%) with presumed clinical cure, after treatment for a mean of 18-49 days with between 1-9 antibiotic regimens. Eight (53%) patients were cured with doxycycline plus moxifloxacin, two (100%) with doxycycline plus pristinamycin, three (75%) with minocycline alone, and three (75%) with prolonged minocycline plus tinidazole treatment.</p><p><strong>Conclusions: </strong>Despite frequent reinfection, most repeat positive tests represented persistent MG infections. All cases achieved cure after initial treatment failure, but many required multiple regimens over several weeks.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149184478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HIV transmission behaviors, detectable HIV-RNA and curable STI prevalence among Ugandan men with HIV with reproductive goals, with and without infertility experiences. 在有生殖目标、有或没有不育经历的乌干达艾滋病毒感染者中,艾滋病毒传播行为、可检测的艾滋病毒rna和可治愈的性传播感染发生率。
IF 1.9 4区 医学
Sexually transmitted diseases Pub Date : 2026-10-09 DOI: 10.1097/OLQ.0000000000002417
Lynn T Matthews, Moran Owembabazi, Tara Wood, Pooja Chitneni, Madeline C Pratt, Patricia M Smith, Dustin M Long, Angela Kaida, Janet M Turan, Esther C Atukunda
{"title":"HIV transmission behaviors, detectable HIV-RNA and curable STI prevalence among Ugandan men with HIV with reproductive goals, with and without infertility experiences.","authors":"Lynn T Matthews, Moran Owembabazi, Tara Wood, Pooja Chitneni, Madeline C Pratt, Patricia M Smith, Dustin M Long, Angela Kaida, Janet M Turan, Esther C Atukunda","doi":"10.1097/OLQ.0000000000002417","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002417","url":null,"abstract":"<p><p>Many men with HIV (MWH) want children. MWH with unmet reproductive goals may prioritize conception over preventing HIV/STI transmission. Therefore, we evaluated whether MWH with unmet versus met reproductive goals were more likely to have detectable HIV-RNA or STIs, and explored socio-structural factors (e.g., HIV/infertility stigma, gender dynamics) conceptualized to influence this association. We recruited 100 MWH in Uganda who reported condomless sex with intent to conceive, half had/had not fathered a child in the last year, defined as \"met\"/\"unmet\" reproductive goals. A questionnaire assessed demographics, sexual and health behaviors, infertility and childbearing stigmas, and socio-structural factors hypothesized to associate with the outcomes of prevalent detectable HIV-RNA or syphilis, gonorrhea, or chlamydia infection. We conducted logistic regression to assess whether unmet reproductive goals were associated with detectable HIV-RNA or STI. We enrolled 100 MWH: 50 had met, 50 had unmet reproductive goals. Median age was 41 (range 24-68). Most (89%) knew their pregnancy partner's HIV serostatus, and 65% reported an HIV-negative partner. 10% had HIV-RNA >200 copies/mL (\"detectable\") and 30% had >1 curable STI. Men reported stigma related to childbearing (4 (1.8-5.0), max 12) and infertility (63.5 (46.0-86.0), max 100). Unmet reproductive goals were not associated with detected HIV-RNA (aOR 0.79, 95%CI 0.14-4.57) or curable STI (aOR 1.02, 95%CI 0.39-2.65). Among MWH, unmet reproductive goals were not associated with HIV viremia or STIs. However, nearly one-third of MWH had curable STIs highlighting opportunities to improve STI screening and care for MWH to optimize the health of MWH, their partners and offspring.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149148938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and associated risk factors of anal high-risk human papillomavirus infection in unvaccinated young men who have sex with men visiting the Center of Sexual Health of Amsterdam. 访问阿姆斯特丹性健康中心的未接种疫苗的与男性发生性行为的年轻男子肛门高危人乳头瘤病毒感染的流行率和相关风险因素。
IF 1.9 4区 医学
Sexually transmitted diseases Pub Date : 2026-10-07 DOI: 10.1097/OLQ.0000000000002423
Sarah van Veelen, Catharina J Alberts, Nina Barendsen, Lobke Massop, Elske Hoornenborg, Sylvia M Bruisten, Johannes A Bogaards, Maarten Schim van der Loeff
{"title":"Prevalence and associated risk factors of anal high-risk human papillomavirus infection in unvaccinated young men who have sex with men visiting the Center of Sexual Health of Amsterdam.","authors":"Sarah van Veelen, Catharina J Alberts, Nina Barendsen, Lobke Massop, Elske Hoornenborg, Sylvia M Bruisten, Johannes A Bogaards, Maarten Schim van der Loeff","doi":"10.1097/OLQ.0000000000002423","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002423","url":null,"abstract":"<p><strong>Background: </strong>Anal high-risk human papillomavirus (hrHPV) is highly prevalent among men who have sex with men (MSM) and the main cause of anal cancer. The effectiveness of HPV vaccination in this population is highly dependent on prior HPV exposure. We aimed to assess the prevalence and determinants of anal hrHPV among young unvaccinated MSM attending the Center for Sexual Health (CSH) of Amsterdam. These findings will serve as a basis for analyses regarding the prophylactic effectiveness and population impact of HPV vaccination among MSM in the Netherlands.</p><p><strong>Methods: </strong>All unvaccinated MSM aged 19-28 years visiting the CSH of Amsterdam during the National 2023-2024 HPV catch-up campaign were eligible. Participants provided socio-demographic and sexual behaviour information, a venous blood sample and anal self-sample. Samples were tested for HPV, HIV, chlamydia, gonorrhoea, and syphilis. HPV DNA-positive anal samples were genotyped using the SPF10 DEIA/LiPA-25 system. Determinants of hrHPV positivity and HPV16/18 were examined using multivariable logistic regression with generalized estimating equations.</p><p><strong>Results: </strong>Among 431 MSM (median age 24 years), 51.0% tested positive for any anal hrHPV-type, 14.6% for HPV16 and 8.1% for HPV18. In multivariable analyses, lifetime number of sexual partners (adjusted odds ratio [aOR] per natural log increase: 1.33, 95%CI 1.16-1.51), inconsistent versus consistent condom use during receptive anal intercourse (aOR 1.68, 95%CI 1.02-2.76) and anal gonorrhoea (aOR 1.51, 95%CI 1.00-2.29) were associated with hrHPV positivity.</p><p><strong>Conclusions: </strong>Prevalence of hrHPV among young unvaccinated MSM is high and associated with sexual behaviours and inconsistent condom use.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current Data to Inform Point-of-Care Testing for Sexually Transmitted Infections in United States Healthcare Settings: A Narrative Review. 目前的数据,以告知点护理测试的性传播感染在美国医疗机构:叙述性回顾。
IF 1.9 4区 医学
Sexually transmitted diseases Pub Date : 2026-10-06 DOI: 10.1097/OLQ.0000000000002422
Beula E Otsyina, Zachary W Lorenz, Lea E Widdice, Haneefa T Saleem, Matthew M Hamill, Khalil G Ghanem, Golsa M Yazdy, Amanda Billiter, Stacey B Griner, Barbara Van Der Pol, Olusegun O Soge, Johan H Melendez, Anne Rompalo, Charlotte A Gaydos, Yukari C Manabe, Susan Tuddenham
{"title":"Current Data to Inform Point-of-Care Testing for Sexually Transmitted Infections in United States Healthcare Settings: A Narrative Review.","authors":"Beula E Otsyina, Zachary W Lorenz, Lea E Widdice, Haneefa T Saleem, Matthew M Hamill, Khalil G Ghanem, Golsa M Yazdy, Amanda Billiter, Stacey B Griner, Barbara Van Der Pol, Olusegun O Soge, Johan H Melendez, Anne Rompalo, Charlotte A Gaydos, Yukari C Manabe, Susan Tuddenham","doi":"10.1097/OLQ.0000000000002422","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002422","url":null,"abstract":"<p><p>Point-of-care testing (POCT) for sexually transmitted infections (STIs) holds promise to improve care across clinical settings in the United States (US). However, multiple barriers to widespread adoption remain, and universal use will not be appropriate. At a minimum, decision-makers require robust, real-world evidence that STI POCTs improve patient outcomes within specific clinical contexts for these tests to be reimbursed and adopted, and data among priority patient groups may help guide targeted utilization. To inform decisions in the US and identify gaps in the evidence base, we reviewed literature on impact of STI POCTs for gonorrhea (NG), chlamydia (CT), trichomoniasis and syphilis on clinical outcomes across emergency departments (EDs), STI/sexual health clinics, primary care and gynecology clinics, and urgent care centers. Because US outcome data are sparse in several settings, we included studies from other high-income regions (Europe, Australia and Canada) noting where findings may not generalize to US practice. Evidence was summarized for priority patient groups (including symptomatic individuals and STI contacts), stratified by sex. We found some evidence for improved outcomes, particularly for symptomatic women in the ED. However, most studies did not stratify results by priority population, and the majority examined ≥90-minute CT/NG tests which, especially outside the ED, returned results only after the visit. Additional research is needed on the impact of STI POCTs on clinical outcomes in priority populations (including ≤30-minute tests), on workflow strategies enabling actionable results before the end of the encounter, and to provide updated cost or cost-effectiveness analyses across US clinical settings.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acceptability of a Prospective Chlamydia Vaccine in Sexually Active Young Adults: A Descriptive Survey. 前瞻性衣原体疫苗在性活跃的年轻人中的可接受性:一项描述性调查。
IF 1.9 4区 医学
Sexually transmitted diseases Pub Date : 2026-10-06 DOI: 10.1097/OLQ.0000000000002421
Stacey B Griner, Sophia R Garza, Idara N Akpan, Alison Footman, Amanda Brosnan, Erika L Thompson, Malinee Neelamegam, Randolph D Hubach
{"title":"Acceptability of a Prospective Chlamydia Vaccine in Sexually Active Young Adults: A Descriptive Survey.","authors":"Stacey B Griner, Sophia R Garza, Idara N Akpan, Alison Footman, Amanda Brosnan, Erika L Thompson, Malinee Neelamegam, Randolph D Hubach","doi":"10.1097/OLQ.0000000000002421","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002421","url":null,"abstract":"<p><strong>Background: </strong>Chlamydia infection rates are high among young adults (YA, ages 18-24). Fortunately, vaccines are being developed to target this pathogen, but chlamydia vaccine acceptability has remained largely unaddressed. The purpose of this descriptive study was to assess the acceptability of a prospective chlamydia vaccine and perceived barriers to receiving such a vaccine among YA.</p><p><strong>Methods: </strong>Sexually active YAs in the United States were recruited for an online survey in May 2022. Participants were asked to indicate their likelihood of being vaccinated for chlamydia, receiving the vaccine if recommended by a doctor, researching the vaccine, and asking their provider about the vaccine (5-point Likert scale). Barriers were listed and participants indicated if each barrier would discourage them. Demographic information was collected, and descriptive analyses were conducted in SAS.</p><p><strong>Results: </strong>Approximately 49% of participants were likely to get a chlamydia vaccine (184/379); this increased to 56% if the vaccine was recommended by a physician (211/379). Only 14% were likely to ask their provider about a chlamydia vaccine (42/295) and 16% were likely to seek additional information about the vaccine (50/320). Barriers with a strong influence included vaccine effectiveness (72%, 273/379), cost (68%, 256/379), and for contracting chlamydia because of the vaccine (66%, 251/379).</p><p><strong>Discussion: </strong>Nearly half of YA are accepting of a chlamydia vaccine, with physician influence likely to increase acceptance. Before implementation, studies should identify effective strategies to educate physicians about their role in vaccine uptake and inform the general population on the safety and effectiveness of the chlamydia vaccine.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Syphilis Screening Among Commercially-Insured Pregnant Women in the United States. 美国商业保险孕妇的梅毒筛查。
IF 1.9 4区 医学
Sexually transmitted diseases Pub Date : 2026-10-06 DOI: 10.1097/OLQ.0000000000002420
Tara E Wood, Jodie A Dionne, Ligong Chen, Joseph A Lewnard, Katia J Bruxvoort
{"title":"Syphilis Screening Among Commercially-Insured Pregnant Women in the United States.","authors":"Tara E Wood, Jodie A Dionne, Ligong Chen, Joseph A Lewnard, Katia J Bruxvoort","doi":"10.1097/OLQ.0000000000002420","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002420","url":null,"abstract":"<p><strong>Background: </strong>Congenital syphilis (CS) incidence increased by 81.7% in the United States (US) between 2020 and 2024. Syphilis screening is recommended at the first prenatal visit and at delivery, but poor compliance may lead to inadequate screening and preventable CS cases.</p><p><strong>Methods: </strong>Using a US-wide collection of longitudinal healthcare claims data, we identified a cohort of commercially-insured pregnant women aged 15-44 years. Women were included if they had a pregnancy resulting in a live birth, stillbirth, or spontaneous abortion during 2017-2021. We described patterns of syphilis screening, diagnoses, and treatment. We also linked women to their infants and examined missed opportunities for CS prevention.</p><p><strong>Results: </strong>Of 728,674 pregnant women, 79.2% received ≥1 syphilis test during pregnancy, and 53.0% received multiple tests. In the first, second, and third trimesters, 41.5%,17.2%, and 31.8% were screened, respectively. The proportion of women receiving ≥1 syphilis test increased by 4.5% between 2017-2021. The median time from pregnancy start to first syphilis screening among those who had any screening was 73 (IQR 56-169) days. Thirty-one women delivered infants with CS. Of these, 28 (90.3%) were screened during pregnancy, 9 (29.0%) were diagnosed with syphilis before delivery, and 6 (19.4%) had documented treatment.</p><p><strong>Conclusion: </strong>These data indicate a systematic gap in syphilis screening among pregnant women, especially in the first trimester, when timely screening may allow for early intervention. Most pregnant women were only screened once, reducing providers' ability to identify syphilis infections. Improved prenatal screening is essential to addressing the CS epidemic.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2026-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149138355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Unknown Duration or Late Syphilis Cases with High Titers-North Carolina, 2015 and 2023. 北卡罗莱纳2015年和2023年高滴度晚期梅毒病例持续时间不详。
IF 1.9 4区 医学
Sexually transmitted diseases Pub Date : 2026-10-01 Epub Date: 2026-07-01 DOI: 10.1097/OLQ.0000000000002379
Daniel J Gore, David A Jackson, Elizabeth Torrone, Erika Samoff, Victoria Mobley, Anna B Cope
{"title":"Unknown Duration or Late Syphilis Cases with High Titers-North Carolina, 2015 and 2023.","authors":"Daniel J Gore, David A Jackson, Elizabeth Torrone, Erika Samoff, Victoria Mobley, Anna B Cope","doi":"10.1097/OLQ.0000000000002379","DOIUrl":"10.1097/OLQ.0000000000002379","url":null,"abstract":"<p><strong>Background: </strong>While recent national increases in unknown duration or late syphilis (UDLS) have outpaced diagnoses of earlier stages of syphilis, the causes and contributors remain unknown. We evaluated changes in the proportion of UDLS cases with high nontreponemal test titers in one jurisdiction to identify if UDLS cases, which often have lower titers compared with early syphilis cases, might increasingly be early syphilitic infections.</p><p><strong>Methods: </strong>We identified UDLS cases with high titers (defined as rapid plasma reagin titers ≥1:32) reported to North Carolina during the years 2015 and 2023. We evaluated changes in case counts and in the proportion of UDLS cases with high titers overall, by demographics, clinical factors, and incarceration history.</p><p><strong>Results: </strong>When comparing years 2015 and 2023, UDLS case counts increased (628 vs 2498). The proportion of cases with high titers remained relatively stable between both years (51.3% vs 50.2%), but increased among women (29.1% vs 46.1%), women pregnant at the time of syphilis diagnosis (30.4% vs 43.2%), men who have sex with women only (45.0% vs 57.4%), and people who were recently incarcerated (41.7% vs 52.9%). The proportion of cases with high titers decreased among men who have sex with men (66.4% vs 58.1%), and men with human immunodeficiency virus (68.0% vs 55.4%).</p><p><strong>Conclusions: </strong>The proportion of cases with high titers increased among women, men who have sex with women only, and people who were recently incarcerated, suggesting that an increasing proportion of UDLS cases in these populations might be early syphilitic infections. Future initiatives could identify methods of improving case staging to facilitate syphilis prevention and control.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"762-768"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148369972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Implementation of Nursing Protocols for Penicillin-Allergy Assessment in a Sexual Health Clinic. 性传播感染门诊青霉素过敏评估护理方案的实施
IF 1.9 4区 医学
Sexually transmitted diseases Pub Date : 2026-10-01 Epub Date: 2026-05-12 DOI: 10.1097/OLQ.0000000000002344
Jessica W Dalby, Helen Hermus, Sharon Conley, Andrea Warren, Cait McCrory
{"title":"Implementation of Nursing Protocols for Penicillin-Allergy Assessment in a Sexual Health Clinic.","authors":"Jessica W Dalby, Helen Hermus, Sharon Conley, Andrea Warren, Cait McCrory","doi":"10.1097/OLQ.0000000000002344","DOIUrl":"10.1097/OLQ.0000000000002344","url":null,"abstract":"<p><p>Penicillin-allergy assessment within sexual health clinics is critical for timely, safe, and effective syphilis treatment among marginalized populations who experience multiple barriers to care. It is also an important public health measure to support antibiotic stewardship in populations at high-risk for antibiotic use. This report describes a quality improvement project in a sexual health clinic that used nursing protocols for penicillin-allergy assessment with a validated risk scoring tool (PEN-FAST) and direct oral amoxicillin challenge. In the first year of protocol implementation, just over 75% of patients with syphilis who reported penicillin allergy were treated safely with benzathine penicillin G.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"e82-e85"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147875570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of Sexual Positioning on Stage of Syphilis at Diagnosis Among Men Who Have Sex With Men. 性定位对男男性行为者梅毒诊断分期的影响
IF 1.9 4区 医学
Sexually transmitted diseases Pub Date : 2026-10-01 Epub Date: 2026-06-22 DOI: 10.1097/OLQ.0000000000002375
Katarina M Bischof, JaNelle M Ricks, Morgan Spahnie, Amiah Matthews, Brittany Liebhard, William C Miller, Jacky M Jennings, Carla Tilchin, Julie Rushmore, Emily R Learner, Abigail N Turner
{"title":"Impact of Sexual Positioning on Stage of Syphilis at Diagnosis Among Men Who Have Sex With Men.","authors":"Katarina M Bischof, JaNelle M Ricks, Morgan Spahnie, Amiah Matthews, Brittany Liebhard, William C Miller, Jacky M Jennings, Carla Tilchin, Julie Rushmore, Emily R Learner, Abigail N Turner","doi":"10.1097/OLQ.0000000000002375","DOIUrl":"10.1097/OLQ.0000000000002375","url":null,"abstract":"<p><strong>Background: </strong>Men who have sex with men (MSM) have a disproportionately high syphilis burden. As anal ulcers are less visible than penile ulcers, we examined whether MSM practicing receptive or versatile versus insertive anal intercourse were more likely to be diagnosed at a later syphilis stage.</p><p><strong>Methods: </strong>Using cross-sectional data from MSM enrolled in the Network Epidemiology of Syphilis Transmission study, we evaluated the associations between sexual positioning (exclusive bottom, versatile bottom, or versatile vs exclusive top or versatile top) and 3 outcomes: (1) syphilis stage diagnosed at baseline (secondary or latent vs primary), (2) lifetime history of syphilis, and (3) history of syphilis in the past 12 months.</p><p><strong>Results: </strong>Overall, 655 MSM enrolled in Network Epidemiology of Syphilis Transmission; 599 had complete data on sexual positioning and syphilis stage at baseline. Of these, 57 had syphilis at baseline (Analysis 1), 506 had complete data on lifetime history of syphilis (Analysis 2), and 377 had complete data on history of syphilis in the past 12 months (Analysis 3). Among MSM with syphilis at baseline, those who practiced receptive or versatile versus insertive anal intercourse had 13 (95% confidence interval = 1.4-123) times the odds of being diagnosed with secondary or latent stage syphilis. Sexual positioning was not associated with syphilis history in the lifetime or past 12 months.</p><p><strong>Conclusions: </strong>These findings suggest that differences in sexual positioning may influence the stage at which syphilis is diagnosed among MSM. Further research in larger samples is needed to better understand these differences and their underlying mechanisms and to assess potential implications for clinical detection and diagnosis.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"693-702"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148284545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sexual Behaviors of Dating Apps Users: A Descriptive Study in the French Population. 约会软件用户的性行为:法国人口的描述性研究。
IF 1.9 4区 医学
Sexually transmitted diseases Pub Date : 2026-10-01 Epub Date: 2026-07-06 DOI: 10.1097/OLQ.0000000000002377
Alexandre Grigolet, Emmanuel Prothon, Hugo Guillermou, Guillaume Dumont
{"title":"Sexual Behaviors of Dating Apps Users: A Descriptive Study in the French Population.","authors":"Alexandre Grigolet, Emmanuel Prothon, Hugo Guillermou, Guillaume Dumont","doi":"10.1097/OLQ.0000000000002377","DOIUrl":"10.1097/OLQ.0000000000002377","url":null,"abstract":"<p><strong>Background: </strong>Sexually transmitted infections remain a major public health concern with rising incidence worldwide. Dating applications have reshaped partner acquisition and sexual networking patterns, yet data on French users remain limited. This study aimed to describe sexual behaviors among dating-app users in France and identify behavioral profiles.</p><p><strong>Methods: </strong>We conducted a cross-sectional survey using an anonymous questionnaire distributed from June to August 2024 through dating applications, social media, and community outreach. Participants reporting dating-app use within the past 12 months were eligible. Descriptive analyses were performed, followed by multiple correspondence analyses to identify behavioral profiles.</p><p><strong>Results: </strong>A total of 230 participants completed the survey (44.3% men, 53.0% women, 2.6% nonbinary), predominantly aged 18 to 30 years. Higher-exposure patterns, including more frequent app use, higher partner turnover, and increased STI screening (71.4% within the past 6 months), were more common among men who have sex with men (MSM). Condom use was inconsistent across sexual practices, with more than 60% of participants reporting never using protection during oral sex. Multiple correspondence analysis revealed three behavioral profiles reflecting a gradient of exposure and prevention: a lower-exposure profile primarily involving men who have sex with women (MSW), a higher-exposure profile predominantly involving MSM, and an intermediate profile mainly involving women who have sex with men (WSM).</p><p><strong>Conclusions: </strong>Dating-app users in France are not behaviorally homogeneous. Distinct profiles reveal misalignment between exposure, prevention, and screening engagement, highlighting the need for sexual health strategies beyond exposure-based assumptions.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"673-678"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148376983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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