Sexually transmitted diseases最新文献_第4页

Formalizing Partnerships: How Regional Coalitions in Sexual Health Can Address the STI Epidemic. 正式确立伙伴关系：性健康区域联盟如何应对性传播感染流行。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-03-04 DOI: 10.1097/OLQ.0000000000002155

Gillian J Lee, Karen A Wendel, Adrean Riba, Lawrence Weingarten, Anne Trolard, Teri S Anderson, Helen Burnside, Hilary Reno

{"title":"Formalizing Partnerships: How Regional Coalitions in Sexual Health Can Address the STI Epidemic.","authors":"Gillian J Lee, Karen A Wendel, Adrean Riba, Lawrence Weingarten, Anne Trolard, Teri S Anderson, Helen Burnside, Hilary Reno","doi":"10.1097/OLQ.0000000000002155","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002155","url":null,"abstract":"Abstract: Background: STI rates continue to increase nationally with more STIs diagnosed outside of traditional STI clinics. Collective impact groups that harness the power of collaboration among diverse community stakeholders have had demonstrated success in supporting local efforts in HIV prevention and addressing specific community gaps. We describe the efforts of two jurisdictional collective impact groups, the St. Louis STI Regional Response Coalition (STIRR) and the Denver Metro STI Coalition (DMSC), to combat their regional STI epidemics.Methods: STIRR and DMSC serve multiple counties (STIRR 12; DMSC 5) and have diverse member organizations including health departments, academic medical and community health centers, and community-based organizations (STIRR 25; DMSC 22). They also have a broad membership base (STIRR 50; DMSC 107). Coordination of these groups is supported by state and institutional funding as well as by staff from the Center for Disease Control and Prevention regional STI Clinical Prevention Training Centers.Results: STIRR and DMSC outcomes include assessments of client STI services, consultation on health department STI data dashboards, development of regional prevention strategies, dissemination of standards of care and best practices for providers, and collaboration with local HIV prevention Fast Track Cities Initiatives. Products to support healthcare staff and community members in STI prevention and care are posted on each group's website.Conclusions: STIRR and DMSC demonstrate the feasibility of utilizing the collective impact model to address jurisdictional STI epidemics. Expansion of community engagement and sustained funding are needed to fully realize the potential of such collaborative groups in addressing the U.S. STI epidemic.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Syphilis screening during pregnancy in 18- to 49-year-old women in commercially-insured claims data, 2022. 2022年商业保险索赔数据中18至49岁妇女怀孕期间的梅毒筛查。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-03-04 DOI: 10.1097/OLQ.0000000000002089

Brian Emerson, Tao Guoyu, Kaitlin Hufstetler, Ryan Cramer, William S Pearson

{"title":"Syphilis screening during pregnancy in 18- to 49-year-old women in commercially-insured claims data, 2022.","authors":"Brian Emerson, Tao Guoyu, Kaitlin Hufstetler, Ryan Cramer, William S Pearson","doi":"10.1097/OLQ.0000000000002089","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002089","url":null,"abstract":"Background: Syphilis cases continue to climb in the United States, with a 159% increase among women between 2018 and 2022. Congenital syphilis (CS) cases continued along the same trajectory, with a 183% increase over the same time frame. Adherence to the screening guidelines may assist in reducing this trend. Our analysis aimed to determine the proportion of commercially-insured women receiving syphilis screening during pregnancy.Materials and methods: We analyzed the 2022 Merative™ MarketScan® Database containing commercially-insured medical claims to determine syphilis screening rates among insured pregnant women aged 18-49 years old, insured for eight months prior to childbirth. Screening events were classified into three categories: 1st (1-13 weeks), 2nd (14-27 weeks), and 3rd (28+ weeks). Percentages and odds ratios were calculated for pregnancy categories by age category, trimester, Centers for Medicare and Medicaid Services (CMS) regions, employment, and type of health insurance.Results: Of the 170,005 pregnant women in the sample, 79.6% were screened for syphilis at least once, and 95.1% resided in a state requiring syphilis testing during pregnancy. The highest percentage of pregnant women were screened during the 3rd trimester, and the majority of those screened received at least 2 tests during pregnancy. Women in states with laws had 14% greater odds for receiving any screening during pregnancy.Discussion: Despite Centers for Disease Control and Prevention (CDC) syphilis screening recommendations, only 79.6% received screening among this insured population. Effective communication on the importance of syphilis screening for all medical providers and their patients may increase the screening rates and decrease the incidence of CS.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tolerance and biofilms could explain the gonococcal treatment failure reported by Morton et al. 耐受性和生物膜可以解释Morton等人报道的淋球菌治疗失败。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-03-04 DOI: 10.1097/OLQ.0000000000002156

Sheeba Manoharan-Basil, Chris Kenyon

引用次数: 0

An Updated Spreadsheet Tool to Estimate the Health and Economic Benefits of STI and HIV Prevention Activities. 估计性传播感染和艾滋病毒预防活动的健康和经济效益的更新电子表格工具。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-03-03 DOI: 10.1097/OLQ.0000000000002147

Harrell W Chesson, Austin M Williams, Bahareh Ansari, Md Hafizul Islam, Britney L Johnson, Dayne Collins, Thomas L Gift, Erika G Martin

{"title":"An Updated Spreadsheet Tool to Estimate the Health and Economic Benefits of STI and HIV Prevention Activities.","authors":"Harrell W Chesson, Austin M Williams, Bahareh Ansari, Md Hafizul Islam, Britney L Johnson, Dayne Collins, Thomas L Gift, Erika G Martin","doi":"10.1097/OLQ.0000000000002147","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002147","url":null,"abstract":"Background: This manuscript describes an updated spreadsheet tool that sexually transmitted infection (STI) prevention programs in the United States can use to estimate the health and economic benefits of their STI and HIV prevention activities.Methods: The development of the updated tool, STIC (Sexually Transmitted Infection Costs) Figure 2.0, involved two main components. First, we revised the tool to be more useful and user-friendly based on feedback from focus groups and usability testing. Second, we updated the mathematical model behind the calculations by (1) revising the model to reflect current STI and HIV prevention activities in the United States, (2) updating the epidemiological and economic parameters in the model using the best available evidence, and (3) including ranges (not just point estimates) in the model output. To demonstrate the use of STIC Figure 2.0, we applied it to estimate the impact of a hypothetical prevention program, consistent with that of a health department or large STI clinic in a metropolitan area.Results: STIC Figure 2.0 incorporated new features, including an interactive user interface to explore findings and create customized charts for use in reports and presentations. The hypothetical example we analyzed illustrated how providing STI treatment to 2,680 people and HIV prevention services to 325 people could avert 1,253 adverse outcomes and save over $2 million in medical costs and productivity costs.Conclusions: Although subject to important limitations, STIC Figure 2.0 allows state and local programs, including STI clinics, to calculate evidence-based estimates of the impact of their program activities.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of Three Treatment Regimens for Latent Syphilis of Late or Unknown Duration Using Public Health Surveillance Data. 利用公共卫生监测资料对晚期或不明病程潜伏性梅毒三种治疗方案的比较

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-03-03 DOI: 10.1097/OLQ.0000000000002148

Travis J Hunt, Anna Berzkalns, Chase A Cannon, Tim W Menza, Julia C Dombrowski, Matthew R Golden

{"title":"Comparison of Three Treatment Regimens for Latent Syphilis of Late or Unknown Duration Using Public Health Surveillance Data.","authors":"Travis J Hunt, Anna Berzkalns, Chase A Cannon, Tim W Menza, Julia C Dombrowski, Matthew R Golden","doi":"10.1097/OLQ.0000000000002148","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002148","url":null,"abstract":"Background: The CDC recommends treating latent syphilis of late/unknown duration (LSUD) with three doses of intramuscular benzathine penicillin G (BPG) or twenty-eight days of oral doxycycline. This recommendation lacks high-quality evidence.Methods: Using public health surveillance data from King County, Washington, we conducted a retrospective cohort study comparing rates of serological cure (>2-titer RPR decline) among persons with LSUD following receipt of one of three regimens: one dose of BPG, three doses of BPG, and twenty-eight days of doxycycline. Subjects included persons diagnosed 2007-2020 with initial an RPR >1:2 and follow-up RPR testing 1-36 months post-treatment. We stratified initial RPRs into high- and low-titer (>1:32, <1:32) and compared outcomes using Cox proportional hazards.Results: The study population included 761 persons with median time from treatment to last RPR/serological cure of 219 days (IQR 114-488). Among high-titer persons, serological cure occurred in 36 (88%) of 41, 330 (88%) of 376, and 58 (88%) of 64 receiving single-dose BPG, three-dose BPG, and doxycycline, respectively. Among low-titer persons, serological cure occurred in 4 (31%) of 13, 114 (49%) of 235, and 14 (47%) of 30 receiving single-dose BPG, three-dose BPG, and doxycycline, respectively. Controlling for initial RPR, serological cure did not differ between high-titer persons receiving one- and three-dose BPG (aHR: 0.89; 95% CI: [0.63, 1.26]) or one-dose BPG and twenty-eight days of doxycycline (aHR: 1.03; 95% CI: [0.68, 1.58]).Conclusions: Serological outcomes in high-titer LSUD following one dose of BPG, three doses of BPG, and twenty-eight days of doxycycline are similar.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143542868","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence of Syphilis Among Men Serving in the Militaries of Sub-Saharan Africa. 撒哈拉以南非洲地区军队中男性梅毒感染率。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-03-01 Epub Date: 2024-11-08 DOI: 10.1097/OLQ.0000000000002102

Nicole L Nabors, Bonnie R Tran, Lindsay Dapremont, Stephane Tounouga, Adrinkaye Allao Dounia, Ferdinand Wando, Yiheyis Aytenfisu Semu, Joseph Bn Kowo, Gertrude Ngwata, Romain Bagamboula Mpassi, Stephen Sevalie, Steven T Wiersma

{"title":"Prevalence of Syphilis Among Men Serving in the Militaries of Sub-Saharan Africa.","authors":"Nicole L Nabors, Bonnie R Tran, Lindsay Dapremont, Stephane Tounouga, Adrinkaye Allao Dounia, Ferdinand Wando, Yiheyis Aytenfisu Semu, Joseph Bn Kowo, Gertrude Ngwata, Romain Bagamboula Mpassi, Stephen Sevalie, Steven T Wiersma","doi":"10.1097/OLQ.0000000000002102","DOIUrl":"10.1097/OLQ.0000000000002102","url":null,"abstract":"Background: The 2030 United Nations Agenda for Sustainable Development includes targets to end sexually transmitted infections (STIs) as a major public health threat. Prevalence data of STIs to inform strategies toward this goal are lacking in middle- and low-income countries, especially among men.Methods: Data from Seroprevalence and Behavioral Epidemiology Risk Surveys conducted among militaries in Cameroon, Chad, Democratic Republic of the Congo (DRC), Ethiopia, Liberia, Malawi, Republic of the Congo, and Sierra Leone during 2013-2018 were used to estimate the prevalence of presumed active syphilis among active-duty military men. Associations of active syphilis infection with age, education, marital status, and rank for each country were assessed.Results: The prevalence of active syphilis was less than 1% among men in Cameroon (2018), Ethiopia (2018), Liberia (2018), Malawi (2013), Republic of the Congo (2014), and Sierra Leone (2013). In Chad (2014), 6.2% (95% confidence interval, 5.2%-7.4%; n = 121/1949) of men tested positive for active syphilis. In DRC (2014), the prevalence of active syphilis was 15.5% (95% confidence interval, 14.1%-16.9%; n = 404/2611) among men. Active syphilis was associated with older age in DRC ( P < 0.01), with less education in Chad ( P = 0.03) and DRC ( P < 0.01), and with rank in DRC ( P = 0.048).Conclusions: These data help address a paucity of information on prevalence of STIs in sub-Saharan Africa and demonstrate the need for improved surveillance among men.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"162-168"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ChatGPT Responses to Frequently Asked Questions Regarding Sexually Transmitted Diseases: Considerations. ChatGPT 回答有关性传播疾病的常见问题：注意事项。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-03-01 Epub Date: 2024-11-27 DOI: 10.1097/OLQ.0000000000002111

Amnuay Kleebayoon, Viroj Wiwanitkit

引用次数: 0

The Role of Jail Testing in the Public Health Response to Syphilis in King County, Washington. 监狱检测在华盛顿州金县梅毒公共卫生应对措施中的作用》（The Role of Jail Testing in the Public Health Response to Syphilis in King County, Washington）。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-03-01 Epub Date: 2024-11-27 DOI: 10.1097/OLQ.0000000000002110

Taylor Buck, Luis Enrique Herrera Perales, Anna Berzkalns, Elizabeth Barash, Matthew R Golden, Julia C Dombrowski

{"title":"The Role of Jail Testing in the Public Health Response to Syphilis in King County, Washington.","authors":"Taylor Buck, Luis Enrique Herrera Perales, Anna Berzkalns, Elizabeth Barash, Matthew R Golden, Julia C Dombrowski","doi":"10.1097/OLQ.0000000000002110","DOIUrl":"10.1097/OLQ.0000000000002110","url":null,"abstract":"Background: The incidence of syphilis among cisgender women and heterosexual men in the United States has risen sharply. Public Health - Seattle & King County implemented a voluntary, opt-in syphilis screening program in a jail to reach disproportionately affected populations outside the health care system.Methods: Public Health - Seattle & King County disease intervention specialists conducted syphilis screening 4 days per week in a regional jail. All persons screened January 2022 to March 2023 were included in the analysis. Disease intervention specialists performed point-of-care treponemal-specific tests, collected demographic and risk factor data, worked with jail medical providers to coordinate empiric treatment and confirmatory testing, and determined syphilis history and stage. We categorized persons with reactive rapid tests as \"confirmed,\" \"presumed,\" \"possible,\" or \"not new\" cases based on confirmatory testing and syphilis history. We compared the characteristics of confirmed cases to overall King County syphilis cases using χ2 tests and examined treatment completion by diagnosis category.Results: A total of 1371 persons completed screening; 69 (5.0%) had positive results, of whom 51 (73.9%) had confirmatory testing, and 33 had confirmed infections (2.4% of screened persons). Compared with all King County syphilis cases, confirmed cases were more likely to be cisgender women (30.3% vs. 21.9%) or cisgender heterosexual men (66.7% vs. 20.6%), people living homeless (66.7% vs. 24.3%), or people who use methamphetamine (90.9% vs. 20.3%; P < 0.001 for all comparisons). Among 33 persons with confirmed syphilis, 29 (87.8%) started and 18 (54.5%) completed treatment.Conclusions: Jail screening reached persons at disproportionate risk for syphilis, but treatment was often incomplete.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"135-140"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11794023/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142732712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antenatal Screening for Sexually Transmitted Infections to Improve Maternal and Newborn Outcomes: An Update From 11 Low- and Middle-Income Countries. 产前性传播感染筛查以改善孕产妇和新生儿结局：来自11个低收入和中等收入国家的最新情况。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-03-01 Epub Date: 2024-11-25 DOI: 10.1097/OLQ.0000000000002100

Chibuzor M Babalola, Jeffrey D Klausner

引用次数: 0

Analysis of 2019 Ohio Disease Intervention Specialist Records for Syphilis Cases Using Clustering Algorithms. 使用聚类算法分析 2019 年俄亥俄州疾病干预专家 (DIS) 记录的梅毒病例。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2025-03-01 Epub Date: 2024-10-31 DOI: 10.1097/OLQ.0000000000002091

Payal Chakraborty, Xia Ning, Mary McNeill, David M Kline, Abigail B Shoben, William C Miller, Abigail Norris Turner

{"title":"Analysis of 2019 Ohio Disease Intervention Specialist Records for Syphilis Cases Using Clustering Algorithms.","authors":"Payal Chakraborty, Xia Ning, Mary McNeill, David M Kline, Abigail B Shoben, William C Miller, Abigail Norris Turner","doi":"10.1097/OLQ.0000000000002091","DOIUrl":"10.1097/OLQ.0000000000002091","url":null,"abstract":"Background: Developments in natural language processing and unsupervised machine learning methodologies (e.g., clustering) have given researchers new tools to analyze both structured and unstructured health data. We applied these methods to 2019 Ohio disease intervention specialist (DIS) syphilis records, to determine whether these methods can uncover novel patterns of co-occurrence of individual characteristics, risk factors, and clinical characteristics of syphilis that are not yet reported in the literature.Methods: The 2019 disease intervention specialist syphilis records (n = 1996) contain both structured data (categorical and numerical variables) and unstructured notes. In the structured data, we examined case demographics, syphilis risk factors, and clinical characteristics of syphilis. For the unstructured text, we applied TF-IDF (term frequency multiplied by inverse document frequency) weights, a common way to convert text into numerical representations. We performed agglomerative clustering with cosine similarity using the CLUTO software.Results: The cluster analysis yielded 6 clusters of syphilis cases based on patterns in the structured and unstructured data. The average internal similarities were much higher than the average external similarities, indicating that the clusters were well formed. The factors underlying 3 of the clusters related to patterns of missing data. The factors underlying the other 3 clusters were sexual behaviors and partnerships. Notably, 1 of the 3 consisted of individuals who reported oral sex with male or anonymous partners while intoxicated, and one comprised mainly of males who have sex with females.Conclusions: Our analysis resulted in clusters that were well formed mathematically, but did not reveal novel epidemiological information about syphilis risk factors or transmission that were not already known.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"146-153"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0