Renee Padiernos, Nicole Thornton, Ravikiran Muvva, Arik V Marcell, Jacky M Jennings, Christina M Schumacher
{"title":"Gonorrhea and Early Syphilis Treatment Practices Among Community Health Care Providers in Baltimore City, Maryland.","authors":"Renee Padiernos, Nicole Thornton, Ravikiran Muvva, Arik V Marcell, Jacky M Jennings, Christina M Schumacher","doi":"10.1097/OLQ.0000000000002098","DOIUrl":"10.1097/OLQ.0000000000002098","url":null,"abstract":"<p><strong>Background: </strong>Ensuring patients receive appropriate (Centers for Disease Control and Prevention-recommended) and prompt (≤14 days of specimen collection) treatment is critical to decrease gonorrhea and early syphilis (ES) incidence. The objectives were to (1) quantify treatment performance among community health care providers (CHPs), (2) compare CHP treatment performance to local health department goals, and (3) describe variation in treatment performance by CHP characteristics in Baltimore City, Maryland.</p><p><strong>Methods: </strong>Surveillance data for gonorrhea and ES diagnoses reported between January 2018 and December 2019 were used. Treatment performance measures were calculated for each CHP (gonorrhea: 171 CHPs; ES: 122 CHPs). Measures were (1) percent treated among all diagnoses (goal: ≥90%), (2) percent appropriately treated among diagnoses treated (goal: ≥90% gonorrhea, ≥95% ES), and (3) percent promptly treated among diagnoses appropriately treated (goal: ≥85%). Treatment performance measures and achievement of goals were compared across CHP characteristics.</p><p><strong>Results: </strong>For gonorrhea, median percent treated, appropriately treated, and promptly treated were 71.4%, 95.0%, and 100.0%, respectively; 29.8% met treated goals. The majority achieved appropriately treated (62.9%) and promptly treated (76.8%) goals. Community health care practices reporting high (vs. low) volume of gonorrhea diagnoses less frequently achieved percent-treated goals (12.2% vs. 35.4%, P = 0.008). Median value for all ES treatment performance measures was 100.0%. Most achieved treated (90.2%) and appropriately treated (95.9%) goals. Less than half (49.2%) achieved the promptly treated goal. Community health care practices reporting high (vs. low) volumes of ES less frequently achieved promptly treated goals (33.3% vs. 54.4%, P = 0.045).</p><p><strong>Conclusions: </strong>Substantial gaps in reporting gonorrhea treatment and prompt ES treatment were observed. Practice-level interventions to facilitate reporting gonorrhea treatment and provide prompt ES treatment are needed.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"154-161"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11794021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lisa C Townsend, Shauna L Stahlman, James D Escobar, Angela B Osuna, Theresa M Casey, Erin L Winkler, John W Kieffer, Jason F Okulicz, Heather C Yun, Joseph E Marcus
{"title":"Positivity and Follow-Up Testing of Chlamydia trachomatis and Neisseria gonorrhoeae Infections in Universally Screened Female Basic Military Trainees.","authors":"Lisa C Townsend, Shauna L Stahlman, James D Escobar, Angela B Osuna, Theresa M Casey, Erin L Winkler, John W Kieffer, Jason F Okulicz, Heather C Yun, Joseph E Marcus","doi":"10.1097/OLQ.0000000000002099","DOIUrl":"10.1097/OLQ.0000000000002099","url":null,"abstract":"<p><strong>Introduction: </strong>Follow-up testing is recommended 3 months after patients initially test positive with Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (GC). Follow-up testing adherence in the United States has been reported below one-third of women, even in universally insured populations. We assessed both the positivity of CT and GC infections in female basic military trainees and the rates of follow-up testing for those who tested positive.</p><p><strong>Methods: </strong>Between January 1, 2006, and December 31, 2021, female Air Force Basic Military Trainees were universally screened with urinary nucleic acid amplification testing for CT and GC. Those who tested positive were evaluated to determine demographic information as well as follow-up testing rates. Patients who were evaluated with a repeat CT/GC nucleic acid amplification test within 12 months after a positive CT/GC test result were considered to have received appropriate follow-up.</p><p><strong>Results: </strong>A total of 5022 (5.2%) of 97,168 trainees tested positive for only CT (4749 [4.8%]), only GC (138 [0.1%]), or both CT/GC (135 [0.1%]) during the study period. Those at increased risk of infection were those <24 years of age, Hispanic and Black individuals, those with high school education level, and single women. Of the 4687 still in the military at 3 months after diagnosis, 3268 (69.7%) had repeat testing within 12 months. There was no significant difference in follow-up testing by age, race, educational level, marital status, or organism causing original infection.</p><p><strong>Conclusions: </strong>Follow-up testing among female United States Air Force basic military trainees is higher than in other universally insured populations. This study demonstrates remaining barriers to adherence to recommended guidelines.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"176-180"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elijah Moothedan, Vama Jhumkhawala, Sara Burgoa, Lisa Martinez, Lea Sacca
{"title":"Qualitatively Assessing ChatGPT Responses to Frequently Asked Questions Regarding Sexually Transmitted Diseases.","authors":"Elijah Moothedan, Vama Jhumkhawala, Sara Burgoa, Lisa Martinez, Lea Sacca","doi":"10.1097/OLQ.0000000000002088","DOIUrl":"10.1097/OLQ.0000000000002088","url":null,"abstract":"<p><strong>Background: </strong>ChatGPT, a large language model artificial intelligence platform that uses natural language processing, has seen its implementation across a number of sectors, notably in health care. However, there remains limited understanding regarding the efficacy of ChatGPT in addressing commonly asked questions on public health subjects. This study aimed to investigate whether ChatGPT could appropriately answer frequently asked questions related to sexually transmitted diseases (STDs).</p><p><strong>Methods: </strong>Ten frequently asked questions on STDs were gathered from 25 different government agency websites. The questions were inputted into ChatGPT, and subsequent responses were analyzed for accuracy, clarity, and appropriateness using an evidence-based approach on a 4-point grading scale.</p><p><strong>Results: </strong>Of the responses provided by ChatGPT, 4 were determined to be excellent requiring no clarification and 6 requiring minimal clarification. No responses were graded as unsatisfactory. Additionally, the responses appropriately emphasized consulting a health care specialist.</p><p><strong>Conclusion: </strong>Although the majority of responses required minimal clarification, ChatGPT has the potential to be an effective supplementary tool for patient education. Additional research is necessary to explore possible public health strategies that incorporate artificial intelligence to address concerns related to STDs.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"188-192"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rodney Perkins, Kristin Beima-Sofie, Katerina Christopoulos, Stephanie E Cohen, Aurnell Dright, Julia C Dombrowski, Ashley Gougougui, Pamela Kohler, Anne F Luetkemeyer, Jillian Pintye, Connie Celum
{"title":"Another Tool for the Sexual Health Toolkit: US Health Care Provider Knowledge and Attitudes About Doxycycline Postexposure Prophylaxis to Prevent Bacterial Sexually Transmitted Infections Among Men Who Have Sex With Men.","authors":"Rodney Perkins, Kristin Beima-Sofie, Katerina Christopoulos, Stephanie E Cohen, Aurnell Dright, Julia C Dombrowski, Ashley Gougougui, Pamela Kohler, Anne F Luetkemeyer, Jillian Pintye, Connie Celum","doi":"10.1097/OLQ.0000000000002095","DOIUrl":"10.1097/OLQ.0000000000002095","url":null,"abstract":"<p><strong>Background: </strong>Doxycycline post-exposure prophylaxis (doxy-PEP) reduces chlamydia, gonorrhea, and syphilis infections among men who have sex with men (MSM) and transwomen (TW). Perspectives of health care providers (HCPs) regarding doxy-PEP can inform implementation efforts.</p><p><strong>Methods: </strong>From August 2022 to January 2023, HCPs were recruited from 13 cities with high sexually transmitted infection (STI) rates for semi-structured, in-depth interviews about their awareness of and attitudes toward doxy-PEP for STI prevention. Health care providers were purposively sampled to include people with experience prescribing PrEP and provision of care to MSM. Interviews were conducted virtually via Zoom. Transcripts and debrief reports were analyzed using a directed content analysis approach to explore knowledge, attitudes, and beliefs about doxy-PEP.</p><p><strong>Results: </strong>Among 30 HCPs, almost half (47%) were between 31-40 years of age, 53% identified as male, and 47% reported their sexual orientation as gay or queer. Half (53%) of participants practiced in the South, 43% had >100 MSM in their clinic panel, and 17% had previously prescribed doxy-PEP. We identified four overarching themes: 1) HCPs expressed positive attitudes toward doxy-PEP; 2) antimicrobial resistance concerns limit enthusiasm for some HCPs; 3) additional data about the long-term safety of doxy-PEP would improve their confidence; and 4) development of guidelines would facilitate the prescription of doxy-PEP, including eligibility, dosing instructions, and treatment management.</p><p><strong>Conclusion: </strong>HCPs were motivated to prescribe doxy-PEP with almost 20% already having prescribed it. Guidelines and data about long-term safety, especially antimicrobial resistance, would facilitate introduction of doxy-PEP into clinical practice.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"129-134"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142558788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alison J Goldberg, Devon M Price, Amanda Phi, Maria Ma, Zoe R Edelstein, Sarit A Golub
{"title":"Increasing Engagement in Human Immunodeficiency Virus Prevention Among Cisgender Women in New York City With Sexual Health Self-Testing Kits: A MaxDiff Analysis.","authors":"Alison J Goldberg, Devon M Price, Amanda Phi, Maria Ma, Zoe R Edelstein, Sarit A Golub","doi":"10.1097/OLQ.0000000000002096","DOIUrl":"10.1097/OLQ.0000000000002096","url":null,"abstract":"<p><strong>Background: </strong>Despite accounting for approximately 20% of new human immunodeficiency virus (HIV) diagnoses in the United States, cisgender women are consistently underrepresented and underengaged in HIV prevention services such as HIV testing and preexposure prophylaxis (PrEP). Black and Latina cisgender woman (BLCW) are disproportionately impacted by HIV, and face additional barriers to accessing prevention services due to racial/ethnic bias, sexism, and their intersection. Offering self-testing for sexually transmitted infections (STIs) and HIV is one potential strategy for increasing access to-and engagement in-preventative sexual health care among BLCW.</p><p><strong>Methods: </strong>We conducted a study in consultation with the New York City Department of Health and Mental Hygiene (NYC DOHMH) and their collaborators in order to identify preferences for sexual health kits-including HIV and STI tests-among BLCW in New York City.</p><p><strong>Results: </strong>We assessed the extent to which BLCW would be willing to accept and use HIV and STI self-testing. In addition, we identified the components of potential sexual health kits that would make them most attractive and would most increase the reach of a sexual health kit program in NYC. Finally, we examined differences in acceptability and preferences (by demographic factors, sexual behavior, and past service utilization) that may impact the development of future programs and interventions.</p><p><strong>Conclusions: </strong>Self-testing for STIs and HIV represents a promising strategy for engaging BLCW in preventative sexual health services and increasing access to care.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"181-187"},"PeriodicalIF":2.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11794027/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142606341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Utility of preoperative syphilis screening on the detection of syphilis at a tertiary care center: a retrospective cohort study.","authors":"Shogo Hanai, Yohei Doi, Hitoshi Honda","doi":"10.1097/OLQ.0000000000002144","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002144","url":null,"abstract":"<p><strong>Background: </strong>The incidence of syphilis has been rising globally but effective screening strategies are lacking. Preoperative syphilis screening is commonly performed at Japanese hospitals for infection prevention purposes. However, its effectiveness in improving subsequent management is unclear.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted to assess the effectiveness of universal preoperative syphilis screening testing implemented at a Japanese tertiary care hospital from April 2017 to March 2023. The annual prevalence of positive preoperative treponemal tests was tracked, and subsequent clinical management for patients with a positive test result was investigated. Attributes of patients with a positive result who were more likely to receive further evaluation were also elucidated.</p><p><strong>Results: </strong>In total, 82,439 patients underwent surgery during the study period. Preoperative treponemal testing was performed in 94.8% (78,170/82,439) of the patients. A positive test result was recorded in 544 (0.70%) with an annual positivity rate ranging from 0.61 to 0.83%, whereas the proportion of presumed active syphilis ranged from 0.02 to 0.08%. A total of 85 patients with a positive syphilis screening test, a nontreponemal test with a positive titer, and without history of syphilis were identified. Of those, only 45 patients (52.9%) received further evaluation.</p><p><strong>Conclusion: </strong>The positivity of preoperative treponemal testing was low despite the rising incidence of syphilis in Japan, and the prevalence of presumed active syphilis identified during the preoperative period was even smaller. Routine treponemal testing in the preoperative setting had limited utility in effectively identifying patients with active syphilis.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143516720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Use of Doxycycline and Other Antibiotics as Bacterial Sexually Transmitted Infection Prophylaxis in a US Sample of Primarily Gay and Bisexual Men.","authors":"Hafsa Salim, Hussain Ramzan","doi":"10.1097/OLQ.0000000000002145","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002145","url":null,"abstract":"","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143493467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ronnie M Gravett, Joseph D Tucker, Lynn T Matthews, Barbara Van Der Pol, Greer McCollum, Jason J Ong, Jeanne Marrazzo, Latesha Elopre
{"title":"Promoting Pre-Exposure Prophylaxis to Gay, Bisexual, and Other Men who Have Sex with Men in the US Deep South: A Qualitative Exploration of Promotion Perceptions and Preferences.","authors":"Ronnie M Gravett, Joseph D Tucker, Lynn T Matthews, Barbara Van Der Pol, Greer McCollum, Jason J Ong, Jeanne Marrazzo, Latesha Elopre","doi":"10.1097/OLQ.0000000000002146","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002146","url":null,"abstract":"<p><strong>Background: </strong>Effective HIV pre-exposure prophylaxis (PrEP) promotion is critical to mitigate PrEP disparities, yet there are gaps in understanding how gay, bisexual, and other men who have sex with men (GBM) respond to and prefer PrEP promotion. The Deep South of the United States, a region with high HIV rates and low PrEP uptake, has unique contextual factors that stifle effective PrEP provision and uptake, which could be overcome with effective PrEP promotional messaging.</p><p><strong>Methods: </strong>We conducted an exploratory qualitative study grounded in Andersen's Behavioral Model for Healthcare Utilization. We recruited HIV-negative GBM, aged 18-39 years, from social media, dating apps, and community outreach to complete semi-structured interviews to explore perceptions of and preferences for PrEP promotion. Interview transcripts were inductively and deductively coded for thematic analysis.</p><p><strong>Results: </strong>40 participants completed interviews (median age 28 years, 68% Black, 48% current PrEP users). Three themes emerged: 1) the role of different identities with sub-themes emphasizing diversity to reduce stigma and improve relatability, 2) interpersonal relationships, i.e., friends, partners, and family, affect PrEP promotion, and 3) reduced emphasis on HIV risk in promotions.</p><p><strong>Conclusion: </strong>To see behavior change for seeking PrEP knowledge and PrEP uptake, PrEP promotions must evolve to improve diversity to foster relatability and reduce stigma, harness social networks to efficiently transmit messaging, and tactfully discuss risk behaviors without compounding stigma.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143493367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alissa Davis, Yihang Sun, Julia Chitnis, Rachel Brenner, Sara Landers, Preeti Pathela, Addie Crawley, Mary Ashmore
{"title":"Examining Women's Self-Management Strategies for Recurrent Bacterial Vaginosis in New York City.","authors":"Alissa Davis, Yihang Sun, Julia Chitnis, Rachel Brenner, Sara Landers, Preeti Pathela, Addie Crawley, Mary Ashmore","doi":"10.1097/OLQ.0000000000002142","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002142","url":null,"abstract":"<p><strong>Introduction: </strong>Bacterial vaginosis (BV) is the most prevalent vaginal condition among women, yet limited data exist on how women manage recurring BV and their perceptions of BV triggers. This study aimed to explore women's experiences with BV onset and recurrence, the various self-treatment strategies used, and adherence to medication regimens.</p><p><strong>Methods: </strong>From March 2020-May 2022, we recruited females at birth ages ≥18 years, who had received a BV diagnosis within the past year at one of four New York City Department of Health and Mental Hygiene (NYC DOHMH) sexual health clinics (SHCs) to take part in semi-structured interviews.</p><p><strong>Results: </strong>A total of 41 women participated, with over half (n = 23) from the SHC in the Bronx.Most women identified as non-Hispanic or Hispanic Black (n = 32), and nearly a quarter as bisexual (n = 8). Women cited sexual (e.g., partner infidelity) and non-sexual (e.g., diet, perfumed soaps) triggers for BV recurrence. To reduce BV recurrence, women reported engaging in self-management strategies like dietary and hygiene changes, including some practices (e.g., increased douching) that are known to exacerbate BV. Some women reported low adherence to the seven-day metronidazole pill regimen, primarily due to side effects.</p><p><strong>Discussion: </strong>Findings highlight self-management strategies women use to reduce BV recurrence and indicate further education about which strategies may be helpful or harmful is needed. Some patients may need additional BV medication adherence support for multi-day dosing of oral metronidazole or access to alternate treatment regimens.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459596","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jeromie Ballreich, K Davina Frick, Steve Huettner, Jamie Perin, Charlotte Gaydos, Jennifer Anders, Richard Rothman, Maria Trent
{"title":"Cost-effectiveness Analysis of the Technology-Enhanced Community Health Nursing Program for Adolescent Girls and Young Adult Women with Pelvic Inflammatory Disease.","authors":"Jeromie Ballreich, K Davina Frick, Steve Huettner, Jamie Perin, Charlotte Gaydos, Jennifer Anders, Richard Rothman, Maria Trent","doi":"10.1097/OLQ.0000000000002143","DOIUrl":"10.1097/OLQ.0000000000002143","url":null,"abstract":"<p><strong>Background: </strong>Pelvic inflammatory Disease (PID) disproportionately impacts adolescents and young adult women. The Technology-Enhanced Community Health Nursing (TECH-N) trial demonstrated the potential benefit of a novel community health intervention for adolescents with PID. We assess the cost-effectiveness of TECH-N compared to standard care.</p><p><strong>Methods: </strong>We constructed a cohort Markov model to assess the cost-effectiveness of TECH-N for adolescents with PID in an urban setting. The model used nine health states: PID, two states for STIs, four states for PID sequelae, recovery and deceased states. The cohort consisted of 18-year-old female adolescents with mild to moderate PID. Transition probabilities were derived from the TECH-N clinical trial and published literature. Health state utilities were derived from published literature. Intervention costs were estimated using TECH-N data, and health state costs were derived from published literature and public databases. The model took a health system perspective over a 10-year time horizon. Sensitivity analyses were used to assess uncertainty. Cost-effectiveness was estimated using the discounted incremental cost-effectiveness ratio (ICER) with effects measured in quality-adjusted life years (QALYs).</p><p><strong>Results: </strong>Over ten years, the TECH-N cohort generated 8.16 QALYs per individual at a cost of $20,419 compared to standard care with 8.14 QALYs costing $20,492. The resulting ICER was negative since the intervention produced more QALYs at a lower cost; suggesting TECH-N is cost-saving.</p><p><strong>Conclusions: </strong>Our model suggests the TECH-N intervention yields better outcomes at lower overall costs. Additionally, the nature of TECH-N lends itself to being coupled with other home-health/community strategies, which could further improve its value proposition.</p>","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143459594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}