Sexually transmitted diseases最新文献_第5页

Census Tract-Level Social Vulnerability and Gonorrhea Rates in Central Ohio: Results From the STD Surveillance Network, 2020-2021. 俄亥俄州中部人口普查区级社会脆弱性与淋病发病率：2020-2021 年性传播疾病监测网络的结果。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2024-12-01 Epub Date: 2024-08-08 DOI: 10.1097/OLQ.0000000000002062

Gregory C Chang, Balaji Ramesh, Brittany M Liebhard, Will E Borrasca, Tory Loux, Jessica Horan, Abigail Norris Turner

{"title":"Census Tract-Level Social Vulnerability and Gonorrhea Rates in Central Ohio: Results From the STD Surveillance Network, 2020-2021.","authors":"Gregory C Chang, Balaji Ramesh, Brittany M Liebhard, Will E Borrasca, Tory Loux, Jessica Horan, Abigail Norris Turner","doi":"10.1097/OLQ.0000000000002062","DOIUrl":"10.1097/OLQ.0000000000002062","url":null,"abstract":"Background: Gonorrhea remains a significant burden in central Ohio, particularly in socially disadvantaged communities. This study evaluates gonorrhea case rates and changes from 2020 to 2021, focusing on geographic patterns associated with social vulnerability.Methods: We analyzed gonorrhea case data from the Columbus STD Surveillance Network for 2020 and 2021. Cases were linked to census tracts and categorized into low (0-0.66) or high (0.67-1.0) vulnerability groups based on the Centers for Disease Control and Prevention/Agency for Toxic Substances and Disease Registry Social Vulnerability Index (SVI). We mapped gonorrhea case rates per 100,000 population, stratified by SVI group, and compared changes using Jenks natural breaks to determine cutpoints. High case rates were defined as ≥605 (2020) and ≥532 (2021). A change in case rates was defined as <154 (decrease/no change) or ≥154 (increase). Demographic factors were summarized for both years.Results: In 2020 and 2021, nearly half of high-SVI tracts had high gonorrhea rates, compared with about 4% to 7% of low-SVI tracts. Median rates in high-SVI tracts were approximately 5 times higher than in low-SVI tracts, with rates of 546 and 598 per 100,000 in 2020 and 2021, compared with 98 and 104 per 100,000, respectively. Gonorrhea rates increased in 23 (9%) of low-SVI tracts and 37 (25%) of high-SVI tracts. Demographic characteristics remained consistent between the 2 years.Conclusions: Gonorrhea rates increased in central Ohio between 2020 and 2021, with higher burdens in high-SVI census tracts. Understanding the dynamics of social vulnerability at the community level is crucial for targeting limited STD resources effectively.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"788-793"},"PeriodicalIF":2.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141902962","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Herpes Simplex Type 1 as the Predominant Cause of Genital Herpes in College Students. 单纯疱疹一型是大学生生殖器疱疹的主要病因。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2024-12-01 Epub Date: 2024-08-08 DOI: 10.1097/OLQ.0000000000002060

Elizabeth Falk-Hanson, Agustina Marconi, Elena Beatriz Sarrouf, Phoebe Sullivan

{"title":"Herpes Simplex Type 1 as the Predominant Cause of Genital Herpes in College Students.","authors":"Elizabeth Falk-Hanson, Agustina Marconi, Elena Beatriz Sarrouf, Phoebe Sullivan","doi":"10.1097/OLQ.0000000000002060","DOIUrl":"10.1097/OLQ.0000000000002060","url":null,"abstract":"Background: Genital herpes etiology has been shifting to include a greater proportion of herpes simplex virus type 1 (HSV-1) infection in the last few decades. A prior study published in 2003 found that 48.9% of infections in a college health population were HSV-1.Methods: We evaluated the number of positive HSV polymerase chain reaction test results obtained from anogenital sites from undergraduate and graduate students from 2013 to 2022 in a college health clinic setting and analyzed the number caused by HSV-1 and HSV type 2 and compared by sex. This was then compared with the prior study from 1993 to 2001.Results: We received 691 (of 2685 samples) positive polymerase chain reaction results for HSV of both types in the period analyzed. Overall, 600 (86.8%) of these were HSV-1, and 520 (75.2%) were in female patients. The prior study in 1993 to 2001 found that 48.9% (244 of 675) of all positive test results were HSV-1; we observed an increase in the percentage of positive HSV-1 over all positive test results of 1.8 ( χ2 = 16.548; P < 0.001).Conclusions: Our study shows that 86.8% of the positive genital HSV test results from 2013 to 2022 were HSV-1. This shows that most positive HSV test results in this setting are now HSV-1, a substantial increase from the previous study in our clinic.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"784-787"},"PeriodicalIF":2.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141894357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validating ICD-10-CM Diagnostic Codes With Laboratory Test Results for Use in Identifying Chlamydial and Gonococcal Infections Among American Indians and Alaska Natives: Indian Health Service, 2016-2021. 验证 ICD-10-CM 诊断代码与实验室检测结果，用于识别美国印第安人和阿拉斯加原住民中的衣原体和淋球菌感染：印第安人健康服务，2016-2021 年。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2024-12-01 Epub Date: 2024-08-10 DOI: 10.1097/OLQ.0000000000002064

Dana L Haberling, Kerry Mauk, Ethan Bornstein, J Pekka Nuorti, Andria Apostolou

{"title":"Validating ICD-10-CM Diagnostic Codes With Laboratory Test Results for Use in Identifying Chlamydial and Gonococcal Infections Among American Indians and Alaska Natives: Indian Health Service, 2016-2021.","authors":"Dana L Haberling, Kerry Mauk, Ethan Bornstein, J Pekka Nuorti, Andria Apostolou","doi":"10.1097/OLQ.0000000000002064","DOIUrl":"10.1097/OLQ.0000000000002064","url":null,"abstract":"Background: National case rates of chlamydia and gonorrhea (CT/GC) among American Indian and Alaska Native (AI/AN) persons are disproportionately high. The Indian Health Service (IHS), which provides health care to members of federally recognized tribes, does not currently have a dedicated CT/GC surveillance system. The purpose of this study was to validate the use of CT/GC diagnostic codes for estimating diagnosed CT/GC infections among AI/AN persons who use IHS services.Methods: We conducted a retrospective study using IHS medical records from all persons 15 years and older from 2016 to 2021. We linked records with CT (A56, A74) and GC (A54, O98.2) International Classification of Diseases, 10th Revision, Clinical Modification diagnostic codes to laboratory results within 30 days for each person. We calculated the sensitivity, specificity, and positive and negative predictive values of CT/GC diagnostic codes using laboratory test results as the reference standard.Results: We identified more than 1.6 million CT/GC laboratory tests, and 52,815 CT and 19,971 GC diagnostic codes. Diagnostic code sensitivity was slightly higher for CT (54%) than GC (50%). Specificity, positive predictive value, and negative predictive value were high for CT and GC (range, 83.3%-99.8%). About one-third of CT/GC diagnostic codes could not be linked to a test result.Conclusions: The validation indicates that diagnostic codes align well with linked laboratory test results. However, because of the relatively large number of diagnostic codes and positive test results that could not be linked, combining the 2 would inform more reliable estimates of diagnosed CT/GC infections among AI/AN persons who use IHS for health care.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":"794-802"},"PeriodicalIF":2.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141914053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital Syphilis-Comprehensive Narrative Review of Alternative Antibiotic Treatment for Use in Neonates. 先天性梅毒--新生儿使用替代抗生素治疗的综合叙述性评论。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2024-12-01 Epub Date: 2024-07-24 DOI: 10.1097/OLQ.0000000000002057

Diana D Villarreal, Jennifer Le, Jeffrey D Klausner

引用次数: 0

Describing the Heterogeneity of Clinical Utilization of Congenital Syphilis Diagnostic Modalities Among Major United States Tertiary Children's Hospitals, 2017-2022. 描述2017-2022年美国主要三级儿童医院先天性梅毒诊断方式临床利用的异质性。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2024-12-01 Epub Date: 2024-07-24 DOI: 10.1097/OLQ.0000000000002054

John M Flores, Natalie Grills, Jason M Kane, Lilly Cheng Immergluck, Nikki Kasal, Madan Kumar, Allison H Bartlett

引用次数: 0

Erratum: Julius (Julie) Schachter: A Legend in the STD Field Who Changed the Trajectory of the STD Journal. 勘误：朱利叶斯-沙赫特（Julius (Julie) Schachter）：改变《性病杂志》发展轨迹的性病领域传奇人物。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2024-12-01 DOI: 10.1097/OLQ.0000000000002074

引用次数: 0

Summary of the National Institute of Allergy and Infectious Diseases workshop on Alternative Therapies to Penicillin for the Treatment of Syphilis.

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2024-11-29 DOI: 10.1097/OLQ.0000000000002113

Krista Cato, Eleanore Chuang, Kristie L Connolly, Carolyn Deal, Thomas Hiltke

{"title":"Summary of the National Institute of Allergy and Infectious Diseases workshop on Alternative Therapies to Penicillin for the Treatment of Syphilis.","authors":"Krista Cato, Eleanore Chuang, Kristie L Connolly, Carolyn Deal, Thomas Hiltke","doi":"10.1097/OLQ.0000000000002113","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002113","url":null,"abstract":"Abstract: The dramatic increase in syphilis cases in the United States in recent years is a serious public health concern. Periodic shortages of benzathine penicillin (BPG), the mainstay of syphilis treatment, create challenges for management of syphilis in the U.S. and worldwide. The National Institute of Allergy and Infectious Diseases (NIAID) convened working groups of experts to assess the landscape of syphilis treatments for uncomplicated adult syphilis, syphilis in pregnant persons, congenital syphilis, and neurosyphilis. The working groups came together at a workshop entitled \"Alternative Therapies to Penicillin for the Treatment of Syphilis\" on February 13-14, 2024, to share their findings regarding promising alternative treatments, research gaps, and challenges. Discussions focused on utilizing existing antibiotics, with a preference for those with favorable safety profiles and demonstrated success against syphilis or other infectious diseases. Clinical research on alternative treatments is complicated by the high effectiveness of penicillin and by differences in clinical, physiological, cultural, and socioeconomic considerations across different patient populations and geographic settings. In addition, current diagnostic tests and tests-of-cure create challenges for clinical trial design. Various potential trial designs were discussed, focusing on subjects with different types and stages of disease. This summary of the workshop is presented to inform plans for future research, including clinical trials on alternatives to penicillin for the treatment of syphilis.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142772487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Jail Testing in the Public Health Response to Syphilis in King County, Washington. 监狱检测在华盛顿州金县梅毒公共卫生应对措施中的作用》（The Role of Jail Testing in the Public Health Response to Syphilis in King County, Washington）。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2024-11-27 DOI: 10.1097/OLQ.0000000000002110

Taylor Buck, Luis Enrique Herrera Perales, Anna Berzkalns, Elizabeth Barash, Matthew R Golden, Julia C Dombrowski

{"title":"The Role of Jail Testing in the Public Health Response to Syphilis in King County, Washington.","authors":"Taylor Buck, Luis Enrique Herrera Perales, Anna Berzkalns, Elizabeth Barash, Matthew R Golden, Julia C Dombrowski","doi":"10.1097/OLQ.0000000000002110","DOIUrl":"https://doi.org/10.1097/OLQ.0000000000002110","url":null,"abstract":"Abstract: Background: The incidence of syphilis among cisgender women and heterosexual men in the U.S. has risen sharply. Public Health - Seattle & King County (PHSKC) implemented a voluntary, opt-in syphilis screening program in a jail to reach disproportionately affected populations outside the healthcare system.Methods: PHSKC Disease Intervention Specialists (DIS) conducted syphilis screening four days per week in a regional jail. All persons screened January 2022 - March 2023 were included in the analysis. DIS performed point-of-care treponemal-specific tests, collected demographic and risk factor data, worked with jail medical providers to coordinate empiric treatment and confirmatory testing, and determined syphilis history and stage. We categorized persons with reactive rapid tests as \"confirmed\", \"presumed\", \"possible\", or \"not new\" cases based on confirmatory testing and syphilis history. We compared the characteristics of confirmed cases to overall King County syphilis cases using chi-square tests and examined treatment completion by diagnosis category.Results: 1,371 persons completed screening; 69 (5.0%) had positive results, of whom 51 (73.9%) had confirmatory testing, and 33 had confirmed infections (2.4% of screened persons). Compared to all King County syphilis cases, confirmed cases were more likely to be cisgender women (30.3% vs. 21.9%) or cisgender heterosexual men (66.7% vs. 20.6%), people living homeless (66.7% vs. 24.3%), or people who use methamphetamine (90.9% vs 20.3%) (p < 0.001 for all comparisons). Among 33 persons with confirmed syphilis, 29 (87.8%) started and 18 (54.5%) completed treatment.Conclusions: Jail screening reached persons at disproportionate risk for syphilis, but treatment was often incomplete.","PeriodicalId":21837,"journal":{"name":"Sexually transmitted diseases","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142732712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ChatGPT Responses to Frequently Asked Questions Regarding Sexually Transmitted Diseases: Considerations. ChatGPT 回答有关性传播疾病的常见问题：注意事项。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2024-11-27 DOI: 10.1097/OLQ.0000000000002111

Amnuay Kleebayoon, Viroj Wiwanitkit

引用次数: 0

Efficacy of doxycycline as post-exposure prophylaxis to prevent Neisseria gonorrhea and Treponema pallidum infection: an updated meta-analysis. 多西环素作为暴露后预防药物预防淋病奈瑟菌和苍白链球菌感染的疗效：最新荟萃分析。

IF 2.4 4区医学

Sexually transmitted diseases Pub Date : 2024-11-27 DOI: 10.1097/OLQ.0000000000002112

Matheus Negri Boschiero, Camila Vantini Capasso Palamim, Fernando Augusto Lima Marson

引用次数: 0