Mylène P Jansen, Tom D Turmezei, Kishan Dattani, Dimitri A Kessler, Simon C Mastbergen, Margreet Kloppenburg, Francisco J Blanco, Ida K Haugen, Francis Berenbaum, Wolfgang Wirth, Felix Eckstein, Frank W Roemer, James W MacKay
{"title":"Cartilage thickness distribution and its dependence on demographic, radiographic, and MRI structural pathology in knee osteoarthritis-data from the IMI-APPROACH cohort.","authors":"Mylène P Jansen, Tom D Turmezei, Kishan Dattani, Dimitri A Kessler, Simon C Mastbergen, Margreet Kloppenburg, Francisco J Blanco, Ida K Haugen, Francis Berenbaum, Wolfgang Wirth, Felix Eckstein, Frank W Roemer, James W MacKay","doi":"10.1007/s00256-025-04907-4","DOIUrl":"https://doi.org/10.1007/s00256-025-04907-4","url":null,"abstract":"<p><strong>Objective: </strong>Cartilage surface mapping is a technique that can visualize 3D cartilage thickness variation throughout a joint without a need for arbitrary regional definitions. The objective of this cross-sectional study was to utilize this technique to evaluate the cartilage thickness distribution in knee osteoarthritis patients and to analyze to what extent it depends on demographic, radiographic, and MRI structural pathology strata.</p><p><strong>Methods: </strong>Patients of the IMI-APPROACH cohort were included, with MRIs obtained at 1.5 T or 3 T. Tibial and femoral cartilage segmentation and registration with a canonical surface were performed semi-automatically. Kellgren-Lawrence and OARSI grading were performed on knee radiographs; MOAKS scoring was performed on MRI scans. The association of demographics and radiographic and MRI scorings with cartilage thickness distribution was analyzed with general linear models using statistical parametric mapping.</p><p><strong>Results: </strong>Two hundred eighty-seven patients were included. Male sex and height were positively associated with cartilage thickness particularly in the trochlea and medial femur, respectively, with differences up to 0.5 mm (male vs female), while radiographic joint space narrowing and bone marrow lesions showed region-specific negative associations (up to 0.14-0.5 mm per grade). Kellgren-Lawrence grade, MOAKS meniscal extrusion, and osteophytes showed patterns of positive and negative associations, with increasing grades showing reduced local tibiofemoral cartilage thickness, but greater thickness in the trochlea (both up to 0.2-0.3 mm per grade).</p><p><strong>Conclusions: </strong>Decreased height, female sex, and increasing tibiofemoral pathology were associated with thinner tibiofemoral cartilage. Unexpected results such as consistently thicker cartilage in the anterior femur with increasing disease or osteophytosis states provide opportunities for future research.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143670998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fielding S Fischer, Austin T Gregg, Arvin B Kheterpal, F Joseph Simeone
{"title":"Atypical vertebral body stress fracture in the setting of diffuse idiopathic skeletal hyperostosis.","authors":"Fielding S Fischer, Austin T Gregg, Arvin B Kheterpal, F Joseph Simeone","doi":"10.1007/s00256-025-04911-8","DOIUrl":"https://doi.org/10.1007/s00256-025-04911-8","url":null,"abstract":"<p><p>Diffuse idiopathic skeletal hyperostosis (DISH) is a non-inflammatory arthritis characterized by bridging ossification along the anterolateral spine. Bridging osteophytes in DISH can result in fusion, altering the biomechanics and increasing the risk of unstable spinal fractures. This report details two cases of unusual vertebral body stress fractures in the setting of DISH: a T6 fracture in a 76-year-old male presenting without definite precedent trauma, and an L2 fracture in an 82-year-old female associated with 1 month of prodromal lower back pain radiating to the groin. CT and MR imaging for both patients demonstrated incomplete fractures arising from the midportion of the anterior vertebral body, rounded sclerosis bordering the fracture site as would be seen in a stress fracture, and a marrow edema sign within the vertebral bodies. We propose that these fractures are a subacute atypical vertebral body stress fracture in the setting of DISH that, to our knowledge, has not previously been reported in the literature. It remains unclear whether the fractures detailed in this report are at risk of progressing to complete fractures, potentially resulting in spinal instability. The subacute fracture pattern described in this report should be recognized by radiologists on CT and MR imaging to avoid the potentially devastating consequences of progression to complete fracture and neurologic injury.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ultrasound and magnetic resonance imaging (MRI) assessment of piezogenic papules: A report of three cases.","authors":"Antoine Moraux, Thomas Le Corroller","doi":"10.1007/s00256-025-04906-5","DOIUrl":"https://doi.org/10.1007/s00256-025-04906-5","url":null,"abstract":"<p><p>Piezogenic papules (PP) are protrusions of fat that form within the subcutaneous tissue, which are typically found on the heels. We herein describe the ultrasound (US) presentation (topography, echogenicity, shape, dynamic reducibility, and power Doppler activity) and magnetic resonance imaging features (topography, signal, and shape) of PP in three female patients who were referred to our institution for evaluation of soft tissue nodules of the heel. Then, we discuss the anatomy of the heel fat pad and its implication in the pathophysiology of PP. Because PP consist of herniations of subcutaneous fat from deep macrochambers to superficial microchambers through focal defects in the fibroconjunctive capsule of the heel fat pad, dynamic US can demonstrate the reducibility of PP under probe compression and therefore allows easy differentiation from other soft tissue tumors.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Camilla Toft Nielsen, Marius Henriksen, Cecilie Laubjerg Daugaard, Janus Uhd Nybing, Philip Hansen, Felix Müller, Henning Bliddal, Mikael Boesen, Henrik Gudbergsen
{"title":"The association between articular calcium crystal deposition and knee osteoarthritis, joint pain and inflammation: a cross-sectional study.","authors":"Camilla Toft Nielsen, Marius Henriksen, Cecilie Laubjerg Daugaard, Janus Uhd Nybing, Philip Hansen, Felix Müller, Henning Bliddal, Mikael Boesen, Henrik Gudbergsen","doi":"10.1007/s00256-025-04904-7","DOIUrl":"https://doi.org/10.1007/s00256-025-04904-7","url":null,"abstract":"<p><strong>Objective: </strong>To explore in a cross-sectional fashion if overweight individuals with knee osteoarthritis (OA) and intraarticular calcium crystal (CaC) deposits experience more knee joint inflammation and knee pain compared with individuals without CaC deposits.</p><p><strong>Subjects and methods: </strong>We used pre-randomization imaging data from an RCT, the LOSE-IT trial. Participants with knee OA (clinical diagnosis of knee OA and KLG 1-3) had CT and 3 T MRI of the index knee. CaCs were assessed on CT using the Boston University Calcium Knee Score (BUCKS). The pain subscale of the Knee Injury and Osteoarthritis Outcome Score (KOOS) was used to assess knee pain and to estimate joint inflammation we used static and dynamic contrast-enhanced (DCE) MRI. An independent sample t-test was used to test for a significant difference in KOOS-pain and Analysis of Covariance (ANCOVA) models to test for differences in the static and DCE-MRI variables between the two groups.</p><p><strong>Results: </strong>Of the 158 participants with KOOS-pain available, 19 (12%) had CaC deposits, and of the 115 participants with MRI available, 13 (11.3%) had CaC deposits. We did not find a significant difference in mean KOOS-pain between the two groups; the mean difference was - 2.2 points (95%CI, - 10.86, 6.45). None of the MRI variables were associated with the presence of CaC deposits. Between-group differences were small for all MRI variables, with standardized mean differences ranging from small to medium (0.31-0.56).</p><p><strong>Conclusion: </strong>In individuals with knee OA, we did not find an association between intraarticular CaC deposits and an increase in knee joint inflammation or knee pain.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kwok Yan Li, King Shing Yung, Tsun Fong, Hoi Ming Kwok
{"title":"Diffuse type tenosynovial giant cell tumour in the sinus tarsi in a paediatric patient: a rare case report with radiological and histopathological analysis.","authors":"Kwok Yan Li, King Shing Yung, Tsun Fong, Hoi Ming Kwok","doi":"10.1007/s00256-025-04905-6","DOIUrl":"https://doi.org/10.1007/s00256-025-04905-6","url":null,"abstract":"<p><p>We present a unique case of diffuse tenosynovial giant cell tumour (TSGCT) in the tarsal sinus of a paediatric patient. TSGCTs are uncommon in the foot and ankle with potential misdiagnosis as more common lesions such as ganglionic cysts. There have only been three cases of sinus tarsi TSGCTs reported in the literature, and this is the first report describing the diffuse subtype (D-TSGCT) in this location. The patient presented with ankle swelling. Magnetic resonance imaging revealed a focal nodular lesion in the sinus tarsi, demonstrating low T1/T2 signals with striking blooming artefacts, and indistinct margins with infiltrative nodular deposits upon careful scrutiny. Histopathological examination showed distinctive features of D-TSGCT including haemosiderin deposition, multinodular infiltrative growth pattern and villous architecture. D-TSGCT is more extensive, aggressive, and with higher recurrence rates than the more common localised type (L-TSGCT). Despite the described morphological differences in the literature, imaging alone is not always discriminatory. The presenting case demonstrates the diagnostic challenge of an extra-articular mass-like D-TSGCT mimicking L-TSGCT, reviewing existing radiological knowledge translated from its pathological features and highlighting the importance of comprehensive imaging and histological evaluation. Assessing for the striking blooming of low T1 and T2 signals, lack of peripheral hypointense capsule, indistinct margins as well as multinodular infiltration along the synovium and adjacent soft tissue structures may help distinguish it from the localised type. This report also underscores the need to consider TSGCT as a differential even in atypical anatomical sites.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143626055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Recent advances and insights into imaging of axial spondyloarthritis.","authors":"Robert G W Lambert, Michael J Tuite","doi":"10.1007/s00256-025-04899-1","DOIUrl":"https://doi.org/10.1007/s00256-025-04899-1","url":null,"abstract":"<p><p>Imaging of the axial skeleton is a critical component of the diagnosis, management and follow-up of axial spondyloarthritis which may be difficult on clinical grounds and biological data alone. The sacroiliac joints (SIJ) are anatomically complex with high incidence of normal variation and degenerative change and techniques used to image the SIJ vary widely. Interpretation of MRI scans of the axial skeleton is facilitated by employing consistent protocols in which sequences are designed for the sensitive detection of inflammatory lesions, fat metaplasia and bone erosion. Considerable research has been undertaken in recent years to improve the accuracy of detection of these findings in early disease and detection of structural damage changes that would allow improvements in diagnosis and management of SpA patients. This review will examine recent advances in our understanding of axSpA and discuss innovations in MRI and CT, focusing on how to optimize a standard acquisition protocol for MRI of the SIJ, and discussing how to avoid some common technical pitfalls that may be encountered in MRI clinical practice.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sonja Opper, Samuel Saucedo, Lisa Ercolano, Lulu He
{"title":"Retrospective validation of the Birmingham atypical cartilage tumor imaging protocol (BACTIP) in a single, United States tertiary care center.","authors":"Sonja Opper, Samuel Saucedo, Lisa Ercolano, Lulu He","doi":"10.1007/s00256-025-04900-x","DOIUrl":"https://doi.org/10.1007/s00256-025-04900-x","url":null,"abstract":"<p><strong>Background: </strong>Central cartilage tumors are common incidental lesions around knee and shoulder joints. Differentiation of low-grade chondroid lesions, such as enchondroma from atypical cartilaginous tumor (ACT) is often difficult on imaging given pathologic and radiologic similarities. The Birmingham atypical cartilage tumor imaging protocol (BACTIP) provides a guide to initial assessment and imaging follow-up for incidental indeterminate central cartilage tumors.</p><p><strong>Objective: </strong>This study retrospectively evaluates BACTIP in a United States tertiary care center.</p><p><strong>Methods: </strong>Indeterminate central cartilage tumors in the proximal humerus, distal femur, and proximal tibia of adults were identified by a keyword search in the health network picture archiving and communications systems (PACS). These were categorized into one of seven BACTIP categories based on criteria including size and degree of endosteal scalloping.</p><p><strong>Results: </strong>There were 292 cases that met the inclusion criteria. The final diagnosis of enchondroma was 100% for lesion types IA and IB, 66% for IC, and 50% for IIB; ACT was 33% for IC and 50% for IIB. Of the type IIC lesions, 43% were diagnosed as intermediate or high-grade chondrosarcoma. Pathology diagnosis was dedifferentiated chondrosarcoma in 75% of type III lesions. Chart review and follow-up imaging revealed no delay of diagnosis. The malignant transformation rate in this study was 0.3%.</p><p><strong>Conclusion: </strong>There were no cases where the application of BACTIP would have led to a delayed diagnosis. The BACTIP would serve as a conservative and appropriate imaging follow-up guideline for patients with central cartilage tumors around the shoulder and knee joint.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Manuela Gallo, Laura Manuela Olarte Bermúdez, Alejandra Duarte
{"title":"Commentary to: CT imaging fndings in symptomatic patients with and without revision surgery after reverse shoulder arthroplasty.","authors":"Manuela Gallo, Laura Manuela Olarte Bermúdez, Alejandra Duarte","doi":"10.1007/s00256-025-04903-8","DOIUrl":"10.1007/s00256-025-04903-8","url":null,"abstract":"","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hila Yashar, Ashley Flaman, Adam Frost, Mara Caragea, Bashiar Thejeel
{"title":"Question: New onset right hip pain.","authors":"Hila Yashar, Ashley Flaman, Adam Frost, Mara Caragea, Bashiar Thejeel","doi":"10.1007/s00256-025-04893-7","DOIUrl":"https://doi.org/10.1007/s00256-025-04893-7","url":null,"abstract":"","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143557928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Steven B Soliman, Matthew J Hartwell, Alex Gornitzky, Ira Zaltz
{"title":"Dynamic ultrasound of the hip.","authors":"Steven B Soliman, Matthew J Hartwell, Alex Gornitzky, Ira Zaltz","doi":"10.1007/s00256-025-04902-9","DOIUrl":"10.1007/s00256-025-04902-9","url":null,"abstract":"","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143543371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}