Skeletal RadiologyPub Date : 2025-02-01Epub Date: 2024-06-21DOI: 10.1007/s00256-024-04722-3
Yì Xiáng J Wáng, Wing P Chan, Wei Yu, Ali Guermazi, James F Griffith
{"title":"Quantitative CT lumbar spine BMD cutpoint value for classifying osteoporosis among older Chinese men can be the same as that of older Chinese women, both much lower than the value for Caucasians.","authors":"Yì Xiáng J Wáng, Wing P Chan, Wei Yu, Ali Guermazi, James F Griffith","doi":"10.1007/s00256-024-04722-3","DOIUrl":"10.1007/s00256-024-04722-3","url":null,"abstract":"<p><p>For older Caucasian women and men, the QCT (quantitative CT) lumbar spine (LS) bone mineral density (BMD) threshold for classifying osteoporosis is 80 mg/ml. It was recently proposed that, for older East Asian women, the QCT LS BMD value equivalent to the Caucasian women's threshold of 80 mg/mL is about 45∼50 mg/ml. For a data of 328 cases of Chinese men (age: 73.6 ± 4.4 years) who had QCT LS BMD and DXA LS BMD at the same time and with the DXA BMD value of ≤ 0.613 g/cm<sup>2</sup> to classify osteoporosis, the corresponding QCT LS BMD threshold is 53 mg/ml. Osteoporotic-like vertebral fracture sum score (OLVFss) ≤ -2.5 has been proposed to diagnose osteoporosis. For 316 cases of Chinese men (age:73.7±4.5 years), OLVFss ≤ -2.5 defines an osteoporosis prevalence of 4.4%; to achieve this osteoporosis prevalence, the corresponding QCT LS BMD value is < 47.5 mg/ml. In the China Action on Spine and Hip Status study, a Genant grades 2/3 radiographic 'osteoporotic vertebral fracture' prevalence was 2.84% for Chinese men (total n = 1267, age: 62.77 ± 9.20 years); to achieve this osteoporosis prevalence, the corresponding BMD value was < 42.5 mg/ml. In a study of 357 Beijing older men, according to the clinical fragility fracture prevalence and femoral neck DXA T-score, the QCT LS BMD value to classify osteoporosis was between 39.45 mg/ml and 51.38 mg/ml. For older Chinese men (≥ 50 years), we recommend the cutpoint for the QCT LS BMD definition of osteoporosis to be 45∼50 mg/ml which is the same as the value for Chinese women.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"193-198"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11652400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141432691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Akram Al Ramlawi, Nickolas Nahm, Michael Abdou, Hytham S Salem, John E Herzenberg, Philip McClure
{"title":"Accuracy and precision of in vitro EOS imaging compared to digital radiographs in the measurement of intramedullary lengthening.","authors":"Akram Al Ramlawi, Nickolas Nahm, Michael Abdou, Hytham S Salem, John E Herzenberg, Philip McClure","doi":"10.1007/s00256-025-04879-5","DOIUrl":"https://doi.org/10.1007/s00256-025-04879-5","url":null,"abstract":"<p><strong>Objectives: </strong>Accurate limb length measurement is essential during limb lengthening procedures to prevent neurologic and musculoskeletal complications. Magnetic intramedullary lengthening nails (MILN) rely on radiographs for measurement, but the optimal radiographic technique is not established. This study evaluated the precision and accuracy of EOS imaging versus digital radiography, including calibration techniques and measurement techniques for assessing intramedullary lengthening.</p><p><strong>Methods: </strong>An MILN was inserted into a Sawbones femur, and lengthening measurements from digital X-ray and EOS imaging were compared to external remote control (ERC) results. Measurements were taken with and without calibration using a magnification ball, nail width, or female nail length. Four observers measured the distraction gap, spindle length, full nail length, and male nail length at various hip flexion angles. Precision and accuracy were calculated for each technique.</p><p><strong>Results: </strong>From 576 measurements, EOS imaging demonstrated significantly higher accuracy than digital radiography (83.6% vs. 73.5% absolute accuracy; p < 0.001) when non-calibrated values were included. EOS maintained superior accuracy at 30 mm, 50 mm, and 70 mm of lengthening (p < 0.05), with no difference at 10 mm. Calibration did not affect EOS accuracy, whereas digital radiography was less accurate without calibration (p < 0.001). Distraction gap measurement was the most accurate for both modalities, and 0° hip flexion provided the highest precision. Overall, EOS was more precise (79.4% vs. 71.7% precision rates; p < 0.001).</p><p><strong>Conclusion: </strong>EOS imaging is recommended for limb lengthening measurements due to its superior precision and accuracy. For digital radiographs, careful calibration is essential to achieve accurate measurements.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143075377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skeletal RadiologyPub Date : 2025-02-01Epub Date: 2024-05-31DOI: 10.1007/s00256-024-04716-1
Ariella R Noorily, Syed T Hoda, Jose G Mantilla, Mohammad Samim
{"title":"Sclerosing well-differentiated liposarcoma: two diagnostically challenging mimicker cases and a literature review.","authors":"Ariella R Noorily, Syed T Hoda, Jose G Mantilla, Mohammad Samim","doi":"10.1007/s00256-024-04716-1","DOIUrl":"10.1007/s00256-024-04716-1","url":null,"abstract":"<p><p>Liposarcoma is a malignant soft tissue tumor with several subtypes, the most common of which is well-differentiated liposarcoma (WDL) or atypical lipomatous tumor (ALT). WDL/ALTs are further divided into three histological subtypes, including lipoma-like, sclerosing, and inflammatory. While the majority of these tumors are predominantly fatty, the sclerosing variant demonstrates diverse histologic and radiographic characteristics, including variable amounts of fibrosis and fat. Because of this histological variability and relative rarity, the sclerosing WDL/ALT can present diagnostic dilemmas. We present two cases of sclerosing WDL/ALT, both of which demonstrated high degrees of fibrosis and a paucity of fat, mimicking desmoid fibromatosis and other fibrotic soft tissue tumors. Thus, it is important for radiologists to be aware of the subtypes of liposarcoma and their unique characteristics, and to consider sclerosing WDL/ALT in cases of fibrotic soft tissue tumors.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":"353-358"},"PeriodicalIF":1.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141180959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kamyar Moradi, Bahram Mohajer, Ali Guermazi, Roham Hadidchi, Soheil Mohammadi, Xu Cao, Mei Wan, Frank W Roemer, Shadpour Demehri
{"title":"Statin use and longitudinal bone marrow lesion burden: analysis of knees without osteoarthritis from the Osteoarthritis Initiative study.","authors":"Kamyar Moradi, Bahram Mohajer, Ali Guermazi, Roham Hadidchi, Soheil Mohammadi, Xu Cao, Mei Wan, Frank W Roemer, Shadpour Demehri","doi":"10.1007/s00256-025-04878-6","DOIUrl":"https://doi.org/10.1007/s00256-025-04878-6","url":null,"abstract":"<p><strong>Objectives: </strong>Knee subchondral bone marrow lesions (BMLs) are one of the hallmark features of structural osteoarthritis (OA) and are potential targets for statins' disease-modifying effect. We aimed to determine the association between statin use and longitudinal changes in magnetic resonance imaging (MRI)-based BML volume in participants without radiographic knee OA at baseline.</p><p><strong>Methods: </strong>Using the Osteoarthritis Initiative (OAI) cohort, we classified participants' knees into two categories: statin users (those who consistently used statins from baseline to the fourth year of the cohort) and non-users. We employed a 1:1 ratio propensity score (PS) matching method, adjusting for factors including age, sex, race, BMI, smoking, alcohol use, physical activity, abdominal obesity, and diabetes mellitus. We measured quantitative BML volume using a validated deep learning (DL) algorithm, applied to baseline, year-2, and year-4 intermediate-weighted fat-saturated knee MRIs. The outcome was determined by the differences in the BML volume change between statin users and non-users over the 4-year period.</p><p><strong>Results: </strong>After adjusting for potential confounders, 1502 knees were included (751 statin users and 751 non-users; mean age 63.5 ± 8.7 years, 44.5% female). A Multilevel linear mixed-effects regression model showed that statin use is associated with a smaller increase in BML volume over 4 years (time-treatment interaction effect estimates, 95% confidence interval (CI) - 14.88 mm<sup>3</sup>/year, - 23.04 to - 6.72, P < 0.001).</p><p><strong>Conclusion: </strong>In participants without baseline knee OA, continuous statin use is associated with a reduced longitudinal worsening of BML volume in the tibiofemoral joint, a known structural damage marker linked to downstream OA incidence.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sarah Torabi, Mohadese Ahmadzade, Hamed Ghorani, Masoumeh Sarvari, Hamidreza Rouientan, Kelly Trinh, Gita Manzari Tavakoli, Mahshad Afsharzadeh, Raul Nirmal Uppot, Mohammad Ghasemi-Rad
{"title":"Image-guided cryoablation for palliation of painful bone metastases: a systematic review and meta-analysis.","authors":"Sarah Torabi, Mohadese Ahmadzade, Hamed Ghorani, Masoumeh Sarvari, Hamidreza Rouientan, Kelly Trinh, Gita Manzari Tavakoli, Mahshad Afsharzadeh, Raul Nirmal Uppot, Mohammad Ghasemi-Rad","doi":"10.1007/s00256-025-04877-7","DOIUrl":"https://doi.org/10.1007/s00256-025-04877-7","url":null,"abstract":"<p><strong>Objective: </strong>To assess the efficacy of cryoablation in controlling pain from metastatic bone lesions.</p><p><strong>Materials and methods: </strong>A systematic search of PubMed, Embase, Scopus, Cochrane library, and Web of Science was conducted from inception to April 2024, focusing on cryoablation for palliation of painful bone metastases. The inclusion criteria were as follows: studies involving patients over 18 years of age who were affected by bone metastases; bone metastases treated with stand-alone cryoablation; studies reporting patients' pain levels before and at least at one time point after cryoablation; and studies published in English.</p><p><strong>Results: </strong>A total of 844 articles were initially screened, resulting in 12 articles involving 309 patients included. Pain assessments were conducted at various time points ranging from 1 day to 6 months after the cryoablation procedure. Included studies reported significant improvements in pain scores based on the visual analog scale (VAS), the numeric rating scale (NRS) and brief pain inventory-short form (BPI-SF) following treatment at 1, 4, 8 and 12 weeks. The most notable mean difference between pre- and post-procedure pain scores was observed at 12 weeks, with a standardized mean difference of -3.71 (95% confidence interval [CI]: -5.29 to -2.00; p < 0.001). Regarding pain relief outcomes, by the fourth week, the proportion of patients experiencing pain relief was 0.69 (95% CI: 0.62 to 0.75; p < 0.001).</p><p><strong>Conclusions: </strong>Cryoablation could be an effective method for palliation of painful bone metastases. Further studies are needed to compare its efficacy with other palliative methods and to define its role in cancer management.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143075387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anette Nieminen, Janne Nurminen, Anni Aavikko, Jani Puhakka, Jussi Haapala, Hannes Keemu, Juha Kukkonen, Ari Alho, Panu Uusalo, Keijo Mäkelä, Jussi Kosola
{"title":"Platelet-rich plasma does not influence magnetic resonance imaging findings of the gluteus muscles after total hip arthroplasty through the Hardinge approach.","authors":"Anette Nieminen, Janne Nurminen, Anni Aavikko, Jani Puhakka, Jussi Haapala, Hannes Keemu, Juha Kukkonen, Ari Alho, Panu Uusalo, Keijo Mäkelä, Jussi Kosola","doi":"10.1007/s00256-025-04876-8","DOIUrl":"https://doi.org/10.1007/s00256-025-04876-8","url":null,"abstract":"<p><strong>Objective: </strong>Total hip arthroplasty through the Hardinge approach damages the hip abductor muscles. MRI can be used to assess adverse postoperative events. In this prospective randomized controlled trial, we evaluated MRI findings and whether platelet-rich plasma affected postoperative healing of the gluteal muscles (gluteus medius and minimus).</p><p><strong>Materials and methods: </strong>Forty patients with hip osteoarthritis requiring treatment with total hip arthroplasty, aged between 60 and 76 years, were included. Patients were randomized into two groups: 19 patients in the platelet-rich plasma group and 21 in the placebo group. Platelet-rich plasma or placebo was injected into the gluteus medius tendon incision line during closure. Postoperative hip MRI and plain radiographs were taken 3 and 12 months after surgery.</p><p><strong>Results: </strong>MRI showed fatty atrophy of the gluteal muscles in all 40 patients (100%), gluteal muscle tear in 11 patients (28%), and atrophy in 16 patients (40%) at both 3 and 12 months postoperatively. Fluid collections related to the operated hip joint were seen in 18 patients (45%) at 3 months and 13 patients (33%) at 12 months, heterotopic ossification formation in nine patients (23%) at 3 months, and 12 patients (31%) at 12 months. There were no significant differences in imaging findings between the two groups.</p><p><strong>Conclusion: </strong>MRI can be a valuable tool for evaluating postoperative healing after total hip arthroplasty. Fatty atrophy of the gluteal muscles was a common finding. Platelet-rich plasma injection into the gluteus medius tendon did not improve healing detected by MRI.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143053391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kevin Quinlan, Scott Evans, Petra Balogh, Mahmoud Etaiwi, Rajesh Botchu
{"title":"Test yourself answer: a 67-year-old male with worsening right shoulder pain and restricted range of motion.","authors":"Kevin Quinlan, Scott Evans, Petra Balogh, Mahmoud Etaiwi, Rajesh Botchu","doi":"10.1007/s00256-025-04869-7","DOIUrl":"https://doi.org/10.1007/s00256-025-04869-7","url":null,"abstract":"","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143024468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kevin Quinlan, Scott Evans, Petra Balogh, Mahmoud Etaiwi, Rajesh Botchu
{"title":"Test yourself question: 67 year old male with worsening right shoulder pain and restricted range of motion.","authors":"Kevin Quinlan, Scott Evans, Petra Balogh, Mahmoud Etaiwi, Rajesh Botchu","doi":"10.1007/s00256-025-04870-0","DOIUrl":"https://doi.org/10.1007/s00256-025-04870-0","url":null,"abstract":"","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143010414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Merve Sekizkardes Tutuncu, Savas Sencan, Canan Bilekyigit Kurt, Serdar Kokar, Osman Hakan Gunduz
{"title":"The role of facet joint degeneration in the treatment success of transforaminal epidural steroid injection: a retrospective clinical study.","authors":"Merve Sekizkardes Tutuncu, Savas Sencan, Canan Bilekyigit Kurt, Serdar Kokar, Osman Hakan Gunduz","doi":"10.1007/s00256-025-04868-8","DOIUrl":"https://doi.org/10.1007/s00256-025-04868-8","url":null,"abstract":"<p><strong>Objective: </strong>Transforaminal epidural steroid injection (TFESI) is highly effective in alleviating radicular back pain. While predictive factors for TFESI treatment outcomes have been previously studied, there is a lack of data on the relationship between facet joint degeneration and TFESI efficacy. This study is aimed at studying the impact of facet joint degeneration on TFESI treatment outcomes for unilateral radicular pain.</p><p><strong>Design: </strong>A retrospective analysis was conducted on patients with unilateral radicular pain who underwent lumbosacral TFESI. Pain severity was assessed using the Numerical Rating Scale (NRS) at baseline, 1 h post-procedure, and 3 weeks post-procedure. Degree of facet joint degeneration was evaluated via MRI. Patients were categorized into two groups: low-grade facet joint degeneration group (group 1) and high-grade facet joint degeneration group (group 2).</p><p><strong>Results: </strong>A total of 147 patients were included in the study. NRS scores were significantly higher in group 2 compared to group 1 at the 3rd week follow-up. Treatment success, defined as a ≥ 50% reduction in NRS scores, was also significantly higher in group 1.</p><p><strong>Conclusion: </strong>Facet joint degeneration adversely impacts the treatment success of TFESI. A comprehensive evaluation of facet joint pathologies prior to procedure planning is imperative for optimizing treatment outcomes.</p>","PeriodicalId":21783,"journal":{"name":"Skeletal Radiology","volume":" ","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143010420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}