Sensors International最新文献_第9页

Biosensors for phytohormone Abscisic acid and its role in humans: A review 植物激素脱落酸生物传感器及其在人体中的作用

Sensors International Pub Date : 2023-01-01 DOI: 10.1016/j.sintl.2023.100234

Subodh , Ravina , Priyanka , Jagriti Narang , Hari Mohan

{"title":"Biosensors for phytohormone Abscisic acid and its role in humans: A review","authors":"Subodh , Ravina , Priyanka , Jagriti Narang , Hari Mohan","doi":"10.1016/j.sintl.2023.100234","DOIUrl":"https://doi.org/10.1016/j.sintl.2023.100234","url":null,"abstract":"<div><p>ABA (abscisic acid) is a phytohormone that is important in regulating stress and various pathological conditions in humans. ABA can be ingested exogenously or endogenously, and is naturally produced by stem cells, macrophages, and keratinocytes. ABA mediates immunological reactions such as phagocytosis, chemotaxis, and reactive oxygen species (ROS) production. In humans, LANCL2 serves as an ABA receptor. Depending on the signaling pathway involved, ABA can act as an inflammatory or anti-inflammatory agent. ABA plays a vital role in glucose tolerance, atherosclerosis treatment, prostate cancer dormancy, malaria, type 2 diabetes, and dementia. Various detection methods have been developed to detect ABA, including chromatographic, spectroscopic, and colorimetric assays, as well as high-performance liquid chromatography (HPLC) and mass spectrometry. Biosensors are commonly used to detect analytes in low concentrations. LSPR and FRET sensors are two types of biosensors that have been developed for the detection of ABA. LSPR sensors rely on light interacting with metal nanoparticles to detect analytes, while FRET sensors rely on energy transfer between a donor and acceptor molecule. LSPR sensors offer high sensitivity, label-free detection, and the ability to detect multiple targets simultaneously, while FRET sensors offer high specificity and customizability. Aptamers have recently been used as a substitute for antibodies in biosensors to provide higher sensitivity and lower cost. This review focuses on the role of ABA and the various biosensors used to detect it in the treatment of various diseases in mammals.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"4 ","pages":"Article 100234"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50172729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A hybrid CNN–KNN approach for identification of COVID-19 with 5-fold cross validation 用于识别新冠肺炎的CNN–KNN混合方法，5倍交叉验证

Sensors International Pub Date : 2023-01-01 DOI: 10.1016/j.sintl.2023.100229

Zarin Anjuman Sejuti, Md Saiful Islam

{"title":"A hybrid CNN–KNN approach for identification of COVID-19 with 5-fold cross validation","authors":"Zarin Anjuman Sejuti, Md Saiful Islam","doi":"10.1016/j.sintl.2023.100229","DOIUrl":"10.1016/j.sintl.2023.100229","url":null,"abstract":"<div><p>The novel coronavirus is the new member of the SARS family, which can cause mild to severe infection in the lungs and other vital organs like the heart, kidney and liver. For detecting COVID-19 from images, traditional ANN can be employed. This method begins by extracting the features and then feeding the features into a suitable classifier. The classification rate is not so high as feature extraction is dependent on the experimenters' expertise. To solve this drawback, a hybrid CNN–KNN-based model with 5-fold cross-validation is proposed to classify covid-19 or non-covid19 from CT scans of patients. At first, some pre-processing steps like contrast enhancement, median filtering, data augmentation, and image resizing are performed. Secondly, the entire dataset is divided into five equal sections or folds for training and testing. By doing 5-fold cross-validation, the generalization of the dataset is ensured and the overfitting of the network is prevented. The proposed CNN model consists of four convolutional layers, four max-pooling layers, and two fully connected layers combined with 23 layers. The CNN architecture is used as a feature extractor in this case. The features are taken from the CNN model's fourth convolutional layer and finally, the features are classified using K Nearest Neighbor rather than softmax for better accuracy. The proposed method is conducted over an augmented dataset of 4085 CT scan images. The average accuracy, precision, recall and F1 score of the proposed method after performing a 5-fold cross-validation is 98.26%, 99.42%,97.2% and 98.19%, respectively. The proposed method's accuracy is comparable with the existing works described further, where the state of the art and the custom CNN models were used. Hence, this proposed method can diagnose the COVID-19 patients with higher efficiency.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"4 ","pages":"Article 100229"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886434/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10760043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6

Highly sensitive ammonia sensor using newly synthesized carbazole based hypercrosslinked polymer and tin dioxide 新型咔唑基超交联聚合物与二氧化锡的高灵敏氨传感器

Sensors International Pub Date : 2023-01-01 DOI: 10.1016/j.sintl.2023.100249

Hamid Ramezanipour Penchah , Ahad Ghaemi , Peiman Valipour , Mohamadmahdi Shahbazi

{"title":"Highly sensitive ammonia sensor using newly synthesized carbazole based hypercrosslinked polymer and tin dioxide","authors":"Hamid Ramezanipour Penchah , Ahad Ghaemi , Peiman Valipour , Mohamadmahdi Shahbazi","doi":"10.1016/j.sintl.2023.100249","DOIUrl":"https://doi.org/10.1016/j.sintl.2023.100249","url":null,"abstract":"<div><p>Tin Dioxide (SnO<sub>2</sub>), carbazole based hypercrosslinked polymer (C-HCP), and C-HCP/SnO<sub>2</sub> nanocomposites by different C-HCP weight percent concentration (0.05–0.15 %wt.) were synthesized by precipitation method and used as sensing materials for ammonia sensor. These materials were applied for ammonia detection in various temperature (100–350 °C) and ammonia concentration (100, 200, and 300 ppm). The electrical conductivity of materials was measured at different temperature and decreasing of electrical conductivity observed by temperature increasing. The resistance of sensor in air to that in presence of ammonia was considered as sensor response. According to the results, SnO<sub>2</sub> had much greater conductivity than different concentration of C-HCP/SnO<sub>2</sub> composite under same conditions. The results showed that in maximum sensor response with adding the C-HCP in SnO<sub>2</sub>, the optimum temperature decrease. The optimum temperature for SnO<sub>2</sub> and 0.05, 0.1, and 0.15 %wt. of C-HCP in SnO<sub>2</sub> composites was obtained 300 °C, 250 °C, 200 °C, and 150 °C, respectively. According to the results, the maximum sensor response observed 0.10 %wt. for ammonia detection at 200 °C. The 0.10 %wt. C-HCP in SnO<sub>2</sub> based sensor showed a response three times higher than that by pure SnO<sub>2</sub> in ammonia detection. Finally, the repeatability of sensors to the ammonia was obtained suitable in 3 continuous cycle and the response and reduction times of sensors was measured.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"4 ","pages":"Article 100249"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50172683","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbon nanoparticle-based COVID-19 biosensors 基于碳纳米颗粒的新冠肺炎生物传感器

Sensors International Pub Date : 2023-01-01 DOI: 10.1016/j.sintl.2023.100246

Farzaneh Mirzadeh-rafie , Fatemeh Rahbarizadeh , Nahid Shoaei , Fatemeh Nasiri , Majid Reza Akbarizadeh , Mehrdad Khatami

{"title":"Carbon nanoparticle-based COVID-19 biosensors","authors":"Farzaneh Mirzadeh-rafie , Fatemeh Rahbarizadeh , Nahid Shoaei , Fatemeh Nasiri , Majid Reza Akbarizadeh , Mehrdad Khatami","doi":"10.1016/j.sintl.2023.100246","DOIUrl":"https://doi.org/10.1016/j.sintl.2023.100246","url":null,"abstract":"<div><p>Coronavirus disease (COVID-19) is a new emerged contagious human-to-human infection that broke out in early December 2019, threatens global public health and causing widespread concern. The high lethality and transmission power of this virus introduce it as a dangerous factor and multiplies the importance of its rapid diagnosis. Tests like computerized tomography (CT) scan, and poly-chain reaction (PCR), were very popular at the beginning of the pandemic, But over time, taking into account the high rate of transmission of the disease, the need for fast and cost-effective diagnostic tests with significant sensitivity and specificity such as clustered regularly interspaced short palindromic repeats (CRISPR), Enzyme-Linked Immunosorbent Assay (ELISA), lateral flow assay (LFA), and biosensor was felt more. In this context, there is a global interest in the feasibility of employing nano-biosensors, especially those using carbon and its derivatives as a key material, for the real-time virus detection. The exceptional properties of carbon and the outstanding performance of nano-biosensors in identifying various viruses prompted a feasibility check on this technology. In this article, we have tried to introduce several carbon-based nano biosensors with various limits of detection (LOD) and different characteristics that have been used in identifying and limiting the spread of Covid-19.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"4 ","pages":"Article 100246"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50172685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HER2 targeted noninvasive immunosensor based on pencil graphite electrode for detection of breast cancer 基于笔形石墨电极的HER2靶向无创免疫传感器检测癌症

Sensors International Pub Date : 2023-01-01 DOI: 10.1016/j.sintl.2023.100238

Reeti Chaudhary , Bhawna Nohwal , Hitesh Bhardwaj , Deepa , C.S. Pundir

引用次数: 1

Synthesis of strontium oxide nanoparticlesby probe sonication method: Its photocatalytic activity and electrochemical sensor studies 探针超声法合成氧化锶纳米粒子的光催化活性及电化学传感器研究

Sensors International Pub Date : 2023-01-01 DOI: 10.1016/j.sintl.2023.100231

K.B. Kusuma , M. Manju , C.R. Ravikumar , N. Raghavendra , T. Naveen Kumar , M.R. Anilkumar , H.P. Nagaswarupa , T.R. Shashi Shekhar , H.C. Ananda Murthy , K.U. Aravind

{"title":"Synthesis of strontium oxide nanoparticlesby probe sonication method: Its photocatalytic activity and electrochemical sensor studies","authors":"K.B. Kusuma , M. Manju , C.R. Ravikumar , N. Raghavendra , T. Naveen Kumar , M.R. Anilkumar , H.P. Nagaswarupa , T.R. Shashi Shekhar , H.C. Ananda Murthy , K.U. Aravind","doi":"10.1016/j.sintl.2023.100231","DOIUrl":"https://doi.org/10.1016/j.sintl.2023.100231","url":null,"abstract":"<div><p>In this paper, we report on the synthesis of strontium oxide nanoparticles (SONPs) using a novel probe sonication method. Powder X-ray diffraction (PXRD) was used to characterize the physicochemical properties of the prepared materials, which confirmed that the average SrO crystallite size was 43 nm. The Kubelka-Monk function of diffuse reflectance spectroscopy (DRS) was used to confirm the average energy gap of SONPs (4.06 eV). SONPs have been successfully used in conjunction with inventive photocatalysts to remove dyes such as Methylene Blue (MB) and Acid Green (AG). MBand AG dyes were used as standard dyes to investigate the photocatalytic properties of NPs when exposed to UV light and sunlight.These nanometal oxides photodegrade methylene blue (87.70%) and acid green (71.20%) dyes with remarkable efficiency when exposed to UV light. These nanometal oxides demonstrated superior sensitivity when paracetamol was used as an analyte in cyclic voltammetry tests at various scan speeds (10 mV/s to 50 mV/s). As a result, SONPs may be useful in photocatalytic activity and electrochemical sensor applications.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"4 ","pages":"Article 100231"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50172730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Super capacitor, electrochemical measurement and sun light driven photocatalytic applications of CuFe2O4 NPs synthesized from bio-resource extract 生物资源提取物合成CuFe2O4纳米颗粒的超级电容、电化学测量和太阳光催化应用

Sensors International Pub Date : 2023-01-01 DOI: 10.1016/j.sintl.2023.100237

Giridhar Meenakshi , B.C. Manjunath , S.C. Prashantha , T. Prashanth , B.S. Surendra

{"title":"Super capacitor, electrochemical measurement and sun light driven photocatalytic applications of CuFe2O4 NPs synthesized from bio-resource extract","authors":"Giridhar Meenakshi , B.C. Manjunath , S.C. Prashantha , T. Prashanth , B.S. Surendra","doi":"10.1016/j.sintl.2023.100237","DOIUrl":"https://doi.org/10.1016/j.sintl.2023.100237","url":null,"abstract":"<div><p>The CuFe<sub>2</sub>O<sub>4</sub> nanoparticle has been successfully synthesized from bio-mediated (<em>Aloe-Vera</em>) combustion process. The structural characterization of synthesized nanoparticle was achieved by spectral-characterizations viz; XRD, SEM, FT-IR and optical examinations. The XRD studies displays a spinel cubic phase development of nanoparticle and its average-particle size (19.3 nm). Low band gap energy of synthesized nanoparticle has been recorded to be 2.84 eV using UV–Visible absorption spectroscopy, which impacts to higher photodegradation efficiency. The potential photocatalytic activity of synthesized nanoparticle was examined using Malachite Green (MG) organic dye as a model, which is performed under specific quantities of stock solution (60 ppm) and obtained nanoparticle (50 mg). The photodegradation efficiency of synthesized material was evaluated for MG dye degradation achieved with 87.5% at 140 min under Sun-light. The excellent oxidation-reduction peak potentials were observed for synthesized spinel ferrite nanoparticle modified with carbon paste investigated by electrochemical analysis using 0.1 M KCl in the different scan rates 0.01–0.05 V/s. The charge-discharge studies of CuFe<sub>2</sub>O<sub>4</sub>-graphite electrode at current density (0.4 A/g) was discussed which is well correspondence to pseudo-capacitive behaviour. The synthesized NPs through bio-resources extract has become a potential new insight into multiple practical applications.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"4 ","pages":"Article 100237"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50172688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Effect of additive concentration on crystalline surface of ZnO nanostructures morphology for enhanced humidity sensing 添加剂浓度对ZnO纳米结构结晶表面形貌的影响

Sensors International Pub Date : 2023-01-01 DOI: 10.1016/j.sintl.2022.100211

Muhammad Arif Riza , Yun Ii Go , Sulaiman Wadi Harun , Siti Barirah Ahmad Anas

{"title":"Effect of additive concentration on crystalline surface of ZnO nanostructures morphology for enhanced humidity sensing","authors":"Muhammad Arif Riza , Yun Ii Go , Sulaiman Wadi Harun , Siti Barirah Ahmad Anas","doi":"10.1016/j.sintl.2022.100211","DOIUrl":"https://doi.org/10.1016/j.sintl.2022.100211","url":null,"abstract":"<div><p>Zinc oxide (ZnO) possesses unique nanostructures. Most ZnO nanostructures have yet seen its use as coating for fiber Bragg grating (FBG) sensors. The properties of zinc oxide nanostructure can be greatly influenced by different additives added with the precursor. This study reports on the influence of different concentration of hexamethylenetetramine (HMT) additive towards the humidity sensing capability of zinc oxide coated on FBG sensors. The synthesis of zinc oxide nanostructure was through a modified hydrothermal method. Morphology observation has confirmed a unique hybrid of nanoflake, and porous hemispherical growth of zinc oxide accompanied with elemental analysis for validation. Sensor response towards change in relative humidity is improved by 400% with functional range between 40 and 80 RH%. The concentration of HMT to achieve such performance is 0.05 M with a zinc acetate precursor. The device shows potency with its hybrid nanostructure when integrated with FBG based humidity sensor. Due to its functional range, it can detect relative humidity contents in the air for various industries. The fabricated sensing device is suited for use in industries with several magnetic equipment and requiring many sensor nodes for mapping of data.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"4 ","pages":"Article 100211"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50172719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel synthesis of Cu2ZnAl2O4 nanostructures for photocatalytic and electrochemical sensor applications 用于光催化和电化学传感器应用的新型Cu2ZnAl2O4纳米结构的合成

Sensors International Pub Date : 2023-01-01 DOI: 10.1016/j.sintl.2022.100225

H.V. Harini , H.P. Nagaswarupa , Eneyew Tilahun Bekele , H.C. Ananda Murthy , C.R. Ravikumar

{"title":"Novel synthesis of Cu2ZnAl2O4 nanostructures for photocatalytic and electrochemical sensor applications","authors":"H.V. Harini , H.P. Nagaswarupa , Eneyew Tilahun Bekele , H.C. Ananda Murthy , C.R. Ravikumar","doi":"10.1016/j.sintl.2022.100225","DOIUrl":"https://doi.org/10.1016/j.sintl.2022.100225","url":null,"abstract":"<div><p>Hybrid nanostructured materials currently offer a potential approach for a variety of applications due to improvements in their physio-chemical characteristics. Techniques for XRD, TEM-HRTEM, SAED, and UV-DRS were used to characterize the Cu<sub>2</sub>ZnAl<sub>2</sub>O<sub>4</sub> (CZA) material. Without any secondary phases and with an average crystallite size of 40 nm, X-ray diffraction pattern examination demonstrates the increased crystalline structure. A highly crystalline, polydisperse CZA nanostructure was visible using TEM-HRTEM and SAED. The CZA nanostructure's light-absorbing behavior is presented by UV-DRS analysis, which found that the predicted bandgap energy was 5.0 eV. In this article, we describe an easy chemical synthesis of a hybrid CZA nanostructure that works well as a catalyst to break down the acid red 88 (AR-88) dye under UV, sunlight, and low light conditions. Additionally, it was studied to determine how to modify the working electrode's surface to enable the detection of lead and tin metal ions. With 93.1% of degradation and comparison work on decolorizing AR-88 dye in the presence of both sunlight and darkness, CZA nanostructure was looked at as a potential catalyst for the decolorization of AR-88 dye. By using graphite electrode paste and cyclic voltammetry to analyze the synthesized sample in 1 N KCl, it was discovered that it had outstanding redox reaction and lead and tin detection capabilities.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"4 ","pages":"Article 100225"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50172725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

An enhanced L-lactate biosensor based on nanohybrid of chitosan, iron-nanoparticles and carboxylated multiwalled carbon nanotubes 基于壳聚糖、铁纳米粒子和羧化多壁碳纳米管纳米杂化物的增强型L-乳酸生物传感器

Sensors International Pub Date : 2023-01-01 DOI: 10.1016/j.sintl.2023.100245

Kusum Dagar, Vinay Narwal, C.S. Pundir

{"title":"An enhanced L-lactate biosensor based on nanohybrid of chitosan, iron-nanoparticles and carboxylated multiwalled carbon nanotubes","authors":"Kusum Dagar, Vinay Narwal, C.S. Pundir","doi":"10.1016/j.sintl.2023.100245","DOIUrl":"https://doi.org/10.1016/j.sintl.2023.100245","url":null,"abstract":"<div><p>An enhanced biosensor was developed for the determination of blood lactate in lacto-acidosis patients. The biosensor employed a nanohybrid composed of chitosan/iron oxide nanoparticles and carboxylated multiwalled carbon nanotubes (CHIT/Fe<sub>3</sub>O<sub>4</sub>NPs/c-MWCNTs), electrodeposited onto an Au electrode, followed by covalent immobilization of L-lactate oxidase (LOx) onto this nano-hybrid. The biosensor (LOx/CHIT/Fe<sub>3</sub>O<sub>4</sub>NPs/c-MWCNTs/AuE) exhibited notable improvements in its analytical characteristics such as a rapid response time (4s), a lower detection limit of 0.15 μM and a wider linear range of 1–3000 μM of L-lactic acid. Additionally, it displayed enhanced reproducibility and an extended shelf life of 100 days. The biosensor was employed to measure the concentration of L-lactate in the plasma of both apparently healthy individuals and lacto-acidosis patients. The results showed that the L-lactate concentrations ranged from 112 ± 1.24 to 183 ± 29.15 μmol/L in apparently healthy individuals, whereas it ranged from 2236 ± 33.29 to 4949 ± 72.39 μmol/L in lacto-acidosis patients, which is significantly higher than in apparently healthy individuals. Thus, the integration of the CHIT/Fe<sub>3</sub>O<sub>4</sub>NPs/c-MWCNTs hybrid film in the biosensor led to the enhanced analytical performance of the biosensor.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"4 ","pages":"Article 100245"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50172687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0