Sensors International最新文献

{"title":"Nanosensor for carcinoembryonic antigen (CEA) detection based on a selective growth-regulating mechanism","authors":"Johan A. Farfán,&nbsp;Mary Licuona,&nbsp;Betty C. Galarreta,&nbsp;Yulán Hernández","doi":"10.1016/j.sintl.2025.100344","DOIUrl":"10.1016/j.sintl.2025.100344","url":null,"abstract":"<div><div>Nanomaterial-based biosensors provide high sensitivity and versatility for the detection of target analytes. Particularly, gold nanomaterials are widely employed as signal transducers due to their unique plasmonic properties. When functionalized with aptamers, these nanostructures gain enhanced selectivity, rapid response capability, and cost-effectiveness. However, the instability of large gold nanoparticles can hinder the exploration of various shapes and sizes.</div><div>In this research, two different types of nanoparticles were used for the development of a carcinoembryonic antigen (CEA), a tumoral biomarker for colorectal cancer, nanosensor. It was proposed a system based on gold nanotriangles (AuNTs) functionalized with the amphiphilic polymer polyvinylpyrrolidone (AuNT@PVP) and a hairpin-shaped aptamer selective to CEA biotinylated at the 3′ end and thiolated at the 5′ end (AuNT@PVP@Apt). Specific recognition process was optimized expecting that CEA would trigger the unfolding of the hairpin structure, exposing biotin moieties that enabled subsequent binding of streptavidin-functionalized gold nanoparticles (AuNP@Strept, 3–5 nm in diameter). However, when analyzing the optical changes observed by UV–Vis–NIR spectroscopy and its correlation with the concentration of CEA, it was observed that the main mechanism involved in the detection was a selective growth mechanism of AuNPs, leading to a really simple and easy way of detecting CEA. The results obtained in this study highlight the intricacies of developing such nanosensors and introduce a novel detection method based on a selective growth mechanism that can be further used for detection.</div></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100344"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144514161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modify a dual ridge horn antenna for drone jamming applications","authors":"Alaa Hussein Hilal,&nbsp;Ahmed Hameed Reja,&nbsp;Mohammed J. Mohammed","doi":"10.1016/j.sintl.2025.100334","DOIUrl":"10.1016/j.sintl.2025.100334","url":null,"abstract":"<div><div>In the last decade, the number of drones has been increasing and becoming cheaper relative to the damage they can cause, threatening airports, transportation, and military applications. Jamming on drones is becoming more and more significant. Handheld anti-drone jammer antennas require high-gain directivity beam patterns with narrow half-power beam widths (HPBW) while also covering multiple frequency bands that are used by drones. This work has modified the proposed multiband gain and enhanced the narrow beam utilized by the Dual Ridge Horn Antenna (DRHA) to meet the requirements of drone jamming systems. The proposed antenna can cover GPS <span><math><msub><mrow><mi>L</mi></mrow><mrow><mn>1</mn></mrow></msub></math></span>, 2.45 GHz, and 5.8 GHz. This work presents a DRHA developed utilizing CST Studio and optimized by using genetic algorithm optimization (GA) that has been employed to improve parameters that enhance selected frequencies. One of the standout features of this design is the incorporation of a dielectric microwave lens, which significantly improved the antenna factor This lens has been inventively crafted using three dielectric constant, <span><math><msub><mrow><mi>ɛ</mi></mrow><mrow><mi>r</mi></mrow></msub></math></span> 2.1, 4, and 4.2 at three different diameters 11 cm, 7 cm and 4 cm as well as different thickness 0.9 cm, 1.3 cm and 1.5 cm, respectively. According to impressive simulations the reflection coefficient has been improved from <span><math><mrow><mo>−</mo><mn>12</mn><mo>.</mo><mn>13</mn></mrow></math></span> dB to an incredible <span><math><mrow><mo>−</mo><mn>19</mn><mo>.</mo><mn>7</mn></mrow></math></span> dB at 2.45 GHz. Regarding to the Vector Network Analyzer (VNA) outcomes the practical design improved from <span><math><mrow><mo>−</mo><mn>8</mn><mo>.</mo><mn>25</mn></mrow></math></span> dB to <span><math><mrow><mo>−</mo><mn>18</mn><mo>.</mo><mn>8</mn></mrow></math></span> dB which reflecting a remarkable enhancement of 43.88% after integrating the dielectric lens. The final dimensions of the fabricated antenna, including the feed section, have been defined as (3.65<span><math><mi>λ</mi></math></span> <span><math><mrow><mo>×</mo><mn>2</mn><mi>λ</mi></mrow></math></span> <span><math><mrow><mo>×</mo><mn>2</mn><mi>λ</mi></mrow></math></span>), aligning excellently with relevant works. Finally, the practical design is an agreement match with simulation results, and the measured peak gain is 7.92 dB at 1.575 GHz, 10.9 dB at 2.45 GHz and 15 dB at 5.8 GHz. The proposed antenna would be suitable for use in a portable handheld jamming system on drones.</div></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100334"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143886479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"KCl-leakage-free reference electrode based on Ag2O–TeO2 glass and Ti","authors":"Tadanori Hashimoto ,&nbsp;Masato Kano ,&nbsp;Kyota Fujioka ,&nbsp;Naoki Yasuda ,&nbsp;Atsushi Ishihara ,&nbsp;Takuhisa Komi ,&nbsp;Yuji Nishio","doi":"10.1016/j.sintl.2025.100339","DOIUrl":"10.1016/j.sintl.2025.100339","url":null,"abstract":"<div><div>The primary objective of this study was to develop KCl-leakage-free reference electrodes for biomedical, clinical, and food applications, as well as for use in the semiconductor industry. Accordingly, we developed new reference electrodes based on Ag₂O–TeO₂ glass and Ti, employing Ag₂O–TeO₂ glass/Ti and Ti/Ag₂O–TeO₂ glass/stainless steel (SUS) configurations in particular. The investigations revealed that the pH sensitivity of 25Ag₂O·75TeO₂/Ti (3 %) was significantly lower than that of 25Ag₂O·75TeO₂/SUS (12 %). Ag₇Te₄ observed in Ti samples had a higher Te fraction than Ag₂Te observed in SUS samples. The stronger reducing ability of Ti compared to Fe in SUS facilitated the reduction of Te⁴⁺ ions to Te⁰, which subsequently reacted with Ag⁰. This observation supports the hypothesis that the pH sensitivity of Ag₇Te₄ is lower than that of Ag₂Te. Heat treatment of Ti on 25Ag₂O·75TeO₂/SUS resulted in a gray TiO₂/Ti layer surrounded by ocher-colored precipitates, including the Ag–Te alloy. Increasing the Ti content in Ti/25Ag₂O·75TeO₂/SUS reduced its pH sensitivity. A 1:2 Ti weight ratio achieved a pH sensitivity of 5 %, similar to 25Ag₂O·75TeO₂/Ti (3 %). Dividing Ti into three sections eliminated the central TiO₂/Ti layer, leaving only Ag–Te alloys and TeO₂ as the predominant materials. However, this structural modification had no discernible impact on the pH sensitivity. These findings suggest that Ag–Te alloys and TeO₂ can act as primary pH-responsive sites, with TiO₂/Ti having no significant contribution. Since TeO₂ likely has a higher electrical resistivity than Ag–Te alloys, the observed low pH sensitivity results from that of the minor but electrically conductive Ag–Te alloys. Therefore, 25Ag₂O·75TeO₂/Ti is a promising candidate for developing KCl-leakage-free reference electrodes for pH sensors, offering low pH sensitivity.</div></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100339"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144212349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Wireless temperature calibration for medical centrifuge","authors":"Tianyu Zhu ,&nbsp;Ju Lu ,&nbsp;Jian Shen ,&nbsp;Jie Liu ,&nbsp;Xinqing Xiao","doi":"10.1016/j.sintl.2024.100296","DOIUrl":"10.1016/j.sintl.2024.100296","url":null,"abstract":"<div><p>Based on the complexity and metrological requirements of temperature calibration within the rotor of a medical low-temperature centrifuge, a wireless temperature calibration device for medical centrifuges has been designed and developed. The temperature probe is integrated into the centrifuge tube, and the entire device can be placed inside the rotor of the centrifuge, allowing for the measurement and analysis of the actual temperature of the test solution inside the centrifuge tube under dynamic rotation conditions. Furthermore, the force situation during dynamic calibration is analyzed and performance tested. The calibration device can consistently and dependably achieve dynamic temperature data acquisition under high-speed conditions of medical low-temperature centrifuges, facilitating dynamic temperature calibration within the centrifuge rotor and offering support for centrifuge temperature control processes.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"6 ","pages":"Article 100296"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666351124000184/pdfft?md5=082303b4d730f38f5435b6ecd2576988&pid=1-s2.0-S2666351124000184-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142117262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thank you Note for Reviewers","authors":"","doi":"10.1016/S2666-3511(24)00042-1","DOIUrl":"10.1016/S2666-3511(24)00042-1","url":null,"abstract":"","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"5 ","pages":"Article 100320"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143103443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evolution of SnO2 nanoparticles for the electrochemical sensing of dopamine including photocatalytic toxic dyes degradation","authors":"S.R. Kiran Kumar ,&nbsp;Harisha S ,&nbsp;Jalaja P ,&nbsp;B.K. Jayanna ,&nbsp;K. Yogesh Kumar ,&nbsp;M.S. Anantha","doi":"10.1016/j.sintl.2023.100278","DOIUrl":"https://doi.org/10.1016/j.sintl.2023.100278","url":null,"abstract":"<div><p>In the present study, SnO₂ nanoparticles were synthesized, and their structural features were evaluated by X-ray diffraction (XRD), scanning electron microscopy (SEM), energy dispersive X-ray analysis (EDX) and transmission electron microscopy (TEM) techniques. Modified electrodes (MCPE) were prepared and utilized to access the electrochemical behaviour of dopamine. This study was conducted in a phosphate buffer solution with a pH value of 7.2. The results indicate that the modified carbon paste electrode (MCPE), with a high active surface area, exhibited excellent electrochemical sensing properties and demonstrated good reproducibility and high sensitivity for the electrochemical determination of DA. Potentially interfering compounds were tested at the surface of the proposed sensor, confirming that, they did not interfere with the determination of DA under optimum condition. Additionally, the photocatalytic properties of SnO₂ were evaluated in degradation of cationic and anionic dyes. It was concluded that the higher photocatalytic activity in SnO₂ nanocomposites was attributed to their porosity and high surface area.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"5 ","pages":"Article 100278"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666351123000529/pdfft?md5=fe8198267d52c9ea6876da508bce1d60&pid=1-s2.0-S2666351123000529-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139434488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fabrication and performance of capacitive humidity and strain sensors that incorporate 3D-printed nanocomposite electrodes","authors":"Stefanos Matsalis ,&nbsp;George Paterakis ,&nbsp;Nikos Koutroumanis ,&nbsp;George Anagnostopoulos ,&nbsp;Costas Galiotis","doi":"10.1016/j.sintl.2023.100272","DOIUrl":"https://doi.org/10.1016/j.sintl.2023.100272","url":null,"abstract":"<div><p>This work reports on advances in capacitive humidity and strain sensor technologies through the development of state-of-the-art 3D-printed Interdigitated Electrodes (IDEs) coated with a unique GO/ PVA coating. These IDEs are constructed using a novel composite filament of MWCNTs and polylactic acid (PLA) that offer superior flexural strength and electrical properties compared to conventional polymer matrices.</p><p>We show that the GO/ PVA coating appears to be sensitive over the full range of relative humidity (RH) from 0% to 100%, with a remarkable capacitance change of 300 pF/%RH. Fast response and recovery times of 60 and 42 s, respectively, have been measured outperforming existing works that utilize metal electrodes. Regarding temperature dependence, the coatings endure conditions ranging from ambient to −25 °C, even in the presence of ice. Furthermore, at 50% RH, the sensors are shown to achieve a maximum sensitivity of 34.2 within a strain range of up to 2%.</p><p>In conclusion, this work represents a significant advancement in cutting-edge sensor technologies, offering unprecedented capabilities for humidity and strain sensing performance for a wide range of applications.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"5 ","pages":"Article 100272"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666351123000463/pdfft?md5=c7ef57bf23c7d5c0e5d05b7f92cee431&pid=1-s2.0-S2666351123000463-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139108815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Highly efficient enzyme less glucose sensor based on cross-linked nitrogen-doped graphene aerogel incorporated with ytterbium oxide and decorated with nickel nitride nanoparticles","authors":"Mohammad Mazloum-Ardakani,&nbsp;Negar Shaker-Ardakani,&nbsp;Fatemeh Farbod","doi":"10.1016/j.sintl.2024.100290","DOIUrl":"10.1016/j.sintl.2024.100290","url":null,"abstract":"<div><p>The development of valuable Non-enzymatic glucose sensors relies extensively on the design of sensitive and cost-effective materials with high catalytic activity for the efficient electro-oxidation of glucose. In this work, nitrogen-doped reduced graphene aerogel decorated with Yb₂O₃ nanoparticles (GA:N–Yb₂O₃) was prepared via a simple one-step hydrothermal method. Then this conductive porous three-dimensional scaffold was employed as an excellent substrate for hosting nickel nitride (Ni₃N) nanoparticles (NPs). Electrochemical investigation confirmed the beneficial role of GA:N–Yb₂O₃ for enhancing Ni₃N NPs catalytic activity. This sensor shows low glucose oxidation potential, a low detection limit, and high sensitivity. Using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), chronoamperometry, and amperometry, the electrochemical activity of the electrode towards the oxidation of glucose was investigated. The GA:N–Yb₂O₃/Ni₃N glassy carbon electrode (GCE) modifier was well applied as an electrocatalyst for sensing glucose with the detection limit of 3.9 μM, and the sensitivity of 247.1 μA mM⁻¹cm⁻². Impressively, ascorbic acid, acetaminophen, dopamine, uric acid, and sodium chloride oxidation interference could also be avoided. Nonetheless, the selectivity and stability of the Non-enzymatic glucose sensors were quite good. Hence, this new Non-enzymatic sensor can have a reliable potential application in glucose detection.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"5 ","pages":"Article 100290"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2666351124000123/pdfft?md5=71b3847bd22a899b5978fff2d68597b8&pid=1-s2.0-S2666351124000123-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141978972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design of a high-sensitivity polymer double-slot waveguide sensor for point-of-care biomedical applications","authors":"S. Prasanna Kumaar,&nbsp;A. Sivasubramanian","doi":"10.1016/j.sintl.2023.100255","DOIUrl":"https://doi.org/10.1016/j.sintl.2023.100255","url":null,"abstract":"<div><p>Silicon photonics is a rapidly developing field that offers cost-effective biosensors with improved sensitivity and the potential for interconnecting with other electronic devices for instant disease diagnosis. The Mach Zehnder interferometer architecture (MZI) is a key technology for biosensors, as it detects changes in refractive index (RI) caused by the presence of biomolecules. In this study, a silicon-polymer double-slot waveguide-based MZI was designed, with a small mode area and a large evanescent field to enhance light-analyte interaction. The waveguide was optimized by converting a normal slot waveguide into a double-slot waveguide with varying slot widths. In transmission spectrum, the wavelength shift was measured for both normal and disease samples. Additionally, the loss at a specific wavelength was analyzed to understand the impact of the biomolecule on the sensor performance. The results show that this sensor has a high sensitivity of 2.39 X10^5 nm/RIU, making it a promising candidate for biosensing applications.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"5 ","pages":"Article 100255"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50175754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic methods employing kidney biomarkers clinching biosensors as promising tools","authors":"Neelam Yadav ,&nbsp;Jagriti Narang ,&nbsp;Anil Kumar Chhillar ,&nbsp;Jogender Singh Rana ,&nbsp;Mohd Usman Mohd Siddique ,&nbsp;El-Refaie Kenawy ,&nbsp;Saad Alkahtani ,&nbsp;Mohd Neyaz Ahsan ,&nbsp;Amit Kumar Nayak ,&nbsp;Md Saquib Hasnain","doi":"10.1016/j.sintl.2023.100253","DOIUrl":"https://doi.org/10.1016/j.sintl.2023.100253","url":null,"abstract":"<div><p>Worldwide, there has been an increasing prevalence of kidney disorders for several years. Kidney disorders are characterized by abnormal kidney biomarkers like uric acid, urea, cystatin C, creatinine, kidney injury molecule-1, C-related protein, <em>etc</em>., in the human body. A person suffering from kidney disorders is prone to several other serious health consequences, such as cardiac diseases and renal failure, which can lead to death. However, early diagnosis of kidney disorders requires effective disease management to prevent disease progression. Existing diagnostic techniques used for monitoring kidney biomarker concentration include chromatographic assays, spectroscopic assays, immunoassays, magnetic resonance imaging (MRI), computed tomography (CT), <em>etc</em>. They also necessitate equipped laboratory infrastructure, specific instruments, highly trained personnel working on these instruments, and monitoring kidney patients. Hence, these are expensive and time-consuming. Since the past few decades, a number of biosensors, like electrochemical, optical, immunosensors, potentiometric, colorimetric, <em>etc</em>., have been used to overcome the drawbacks of conventional and modern techniques. These biosensing systems have many benefits, such as being cost-effective, quick, simple, highly sensitive, specific, requiring a minimum sample amount, reliable, and easy to miniaturize. This review article discusses the uses of effectual biosensors for kidney biomarker detection with their potential advantages and disadvantages. Future research needs to be implicated in developing highly advanced biosensors that must be sensitive, economical, and simple so that they can be used for on-site early detection of kidney biomarkers to assess kidney function.</p></div>","PeriodicalId":21733,"journal":{"name":"Sensors International","volume":"5 ","pages":"Article 100253"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"50175755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}