Scientifica最新文献

{"title":"Chemopreventive Effects of Lycopene in miR-21 Knockout and Wild-Type Pancreatic Cancer Cells.","authors":"Basak Dalbayrak, Burcu Taluğ Taştan, Tuğçe Temel, Pinar Obakan Yerlikaya, Pinar Uysal Onganer, Elif Damla Arisan","doi":"10.1155/sci5/8865270","DOIUrl":"10.1155/sci5/8865270","url":null,"abstract":"<p><p>Pancreatic cancer is one of the most lethal malignancies, characterized by late diagnosis, rapid progression, and resistance to conventional therapies. The oncogenic microRNA miR-21 is frequently upregulated in pancreatic tumors and contributes to tumor growth, migration, and chemoresistance by targeting tumor suppressor genes. Lycopene, a naturally occurring carotenoid with antioxidant and anti-inflammatory properties, has shown promise as a chemopreventive agent in several cancer types. This study investigates the therapeutic potential of lycopene in human pancreatic cancer cell lines (PANC-1 and MIA PaCa-2) and their miR-21 knockout counterparts. Treatment with 50 μM lycopene significantly reduced cell viability, colony formation, migration, and spheroid integrity and decreased intracellular reactive oxygen species (ROS) levels, with more pronounced effects in miR-21-deficient cells. These findings highlight the role of miR-21 in modulating lycopene sensitivity and support the potential of lycopene as an adjunctive therapeutic agent in pancreatic cancer.</p>","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":"2026 ","pages":"8865270"},"PeriodicalIF":3.6,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12901648/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146201985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Effectiveness of Grape Seed Extract and Low-Level Laser Therapy in the Management of Dentin Hypersensitivity: A Randomized Controlled Trial.","authors":"Tun Yi Darren Ong, Wei Nee Lim, Li Jia Ong, Ju Wen Lim, Gursimrendeep Kaur, Anchu Rachel Thomas, Venkata Bharatwaj Narasu","doi":"10.1155/sci5/6656174","DOIUrl":"10.1155/sci5/6656174","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effectiveness of grape seed extract (GSE) and its combination with low-level laser therapy (LLLT) in alleviating pain from dentin hypersensitivity (DH) compared to LLLT alone.</p><p><strong>Methods: </strong>Patients aged 20-50 years with at least three sensitive teeth in different quadrants and baseline pain scores ≥ 2 on the visual analog scale (VAS) were recruited. Each tooth was randomly allocated to one of three groups: LLLT + placebo, GSE + placebo, or GSE + LLLT. Pain scores were recorded on Days 1, 3, and 7 using cold and air spray tests.</p><p><strong>Results: </strong>The GSE + LLLT group demonstrated the greatest reduction in pain sensitivity, showing a 72.8% decrease for air spray and 59.51% for the cold test at Day 3, compared to the LLLT or GSE groups alone. However, there were no statistically significant differences (<i>P</i> > 0.05) in pain score reduction among the groups at any time point.</p><p><strong>Discussion: </strong>The combination of GSE and LLLT may enhance early pain reduction in DH compared to individual treatments, but the improvement was not statistically significant. GSE presents a potentially feasible and patient-friendly alternative for DH management, warranting further clinical validation.</p><p><strong>Statistical analysis used: </strong>Data were collected and analyzed using IBM Statistical Package for the Social Sciences (SPSS) software program, Version 20.0 (IBM, Chicago, Illinois). General linear model-repeated measure ANOVA was carried out to assess the reduction in DH pain score among individual interventions and the comparison between the three interventions. The significance level was set at <i>p</i> < 0.05.</p><p><strong>Conclusion: </strong>While GSE combined with LLLT showed the greatest numerical reduction in DH pain scores, the difference was not statistically significant. Further large-scale studies are recommended to confirm the clinical benefits of this combination.</p><p><strong>Trial registration: </strong>ClinicalTrials.gov identifier: NCT05927831.</p>","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":"2026 ","pages":"6656174"},"PeriodicalIF":3.6,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12901653/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Kinetic Investigation of Photocatalytic Degradation of Methyl Orange Dye Using Mg-Doped Ag₂O Nanoparticle.","authors":"Gul Asimullah Khan Nabi, Sajjad Hussain, Mati Ullah, Shohreh Azizi, Ilunga Kamika, Malik Maaza","doi":"10.1155/sci5/8874791","DOIUrl":"10.1155/sci5/8874791","url":null,"abstract":"<p><p>In the current research, the Mg-doped Ag₂O nanoparticles were produced by the coprecipitation method. The characterization of the as-prepared nanoparticles was conducted through a series of techniques. SEM confirmed homogenous morphology of a sphere with minimal agglomeration. The band gap of Mg-AgO₂ was determined to be 2.6 eV. The materials were observed to possess a particle dimension of 23.87 nm. X-ray diffraction (EDX) proved that the substance is 97% Ag, 1.58% oxygen, and 1.42% Mg. The FTIR, PL, DRS, PZC, TEM, and XRD results proved that Mg-doped Ag₂O nanoparticles were successfully doped. In this study, the first application of the synthesized Mg-doped Ag₂O particles was studied for the decolorization of methyl orange in an aqueous solution. At ideal conditions of dye (30 ppm), neutral pH and the dosage of catalyst (0.4 g), 96.1% of decolorization was obtained in 150 min. The degradation was first order and the activation energy was found to be 13.19 kJ/mol. The recyclability of the material was studied, and it was confirmed that the material could be reused multiple times.</p>","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":"2026 ","pages":"8874791"},"PeriodicalIF":3.6,"publicationDate":"2026-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12901649/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146202196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biochar: A Sustainable Solution for Mitigating Greenhouse Gas Emissions and Enhancing Soil Productivity-A Review.","authors":"Aruna Olasekan Adekiya, Ayibanoa Lekoo Ibaba, Timothy Oyebamiji Ogunbode, Olajire Damilola Adedokun","doi":"10.1155/sci5/5690423","DOIUrl":"10.1155/sci5/5690423","url":null,"abstract":"<p><p>Greenhouse gases (GHGs) resulting from human activities significantly impact crop production and agricultural sustainability, necessitating innovative solutions to mitigate their effects. One promising approach is employing biochar for GHG mitigation, providing a potential means to offset emissions and enhance crop productivity sustainably. We conducted a comprehensive review by sourcing reputable academic research from various search engines, focusing on terms such as biochar, methane (CH₄), carbon dioxide (CO₂), nitrous oxide (N₂O), GHG, soil organic carbon, agricultural land and cropland. The whole review was divided into three major portions: GHGs, the effect of GHG emission on crop productivity and biochar as an agent of GHG mitigation and further subtopics were designed under each. The review revealed that GHG emissions, including CO₂, CH₄ and N₂O, detrimentally affect crop productivity, posing a serious threat to global food security. Studies demonstrated that biochar aids in mitigating atmospheric CO₂ by sequestration of C. Studies also demonstrated that biochar can positively influence soil physical properties, such as reducing bulk density and enhancing soil moisture, potentially leading to a decrease in soil N₂O emissions. The decrease in soil N₂O emissions was due to the maintenance of optimal oxygen levels in the soil by biochar. Biochar has been utilized to mitigate methane (CH₄) emissions. The reduction in CH₄ due to biochar can be linked to the inhibitory effect of biochar chemicals on soil methanogens. However, further research and widespread adoption of biochar use are imperative to fully realize its global potential.</p>","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":"2026 ","pages":"5690423"},"PeriodicalIF":3.6,"publicationDate":"2026-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12883893/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146158325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical Profiling and Computational Docking Studies Revealing the Potential Anticancer and Antioxidant Properties of <i>Heliotropium indicum</i> L.","authors":"Sadia Afroz Shoily, Mst Shahnaj Parvin, Mohsin Kazi, Aqibul Hasan Aqib, Md Sabbir Hossain, Rasel Ahmed, Rafat Hossain Rafi, Jaytirmoy Barmon, Mohammad N Uddin, Md Ekramul Islam","doi":"10.1155/sci5/1079290","DOIUrl":"10.1155/sci5/1079290","url":null,"abstract":"<p><p>This study explores the anticancer and antioxidant potential of <i>Heliotropium indicum</i> L. through integrated phytochemical, biological, and computational approaches. GC-MS analysis identified phenol, 3,5-bis(1,1-dimethylethyl) as a major constituent. The chloroform fraction (CHF) exhibited significant <i>in vivo</i> antitumor activity in an Ehrlich ascites carcinoma (EAC) model, showing 76.39% tumor growth inhibition, comparable to bleomycin (80.36%). CHF also demonstrated potent cytotoxicity (LC₅₀ = 28.96 μg/mL) in a brine shrimp assay and protected against AAPH-induced oxidative DNA damage. Molecular docking revealed strong binding of key compounds to topoisomerase II, supported by stable molecular dynamics simulations and favorable MM-PBSA binding energies. These findings highlight <i>H. indicum</i> as a promising source of anticancer and antioxidant agents, warranting further mechanistic and preclinical investigation.</p>","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":"2026 ","pages":"1079290"},"PeriodicalIF":3.6,"publicationDate":"2026-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12872038/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146126328","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Determinants of Fast Food Consumption Among Medical Sciences Students in Kermanshah, Iran.","authors":"Maryam Janatolmakan, Shahab Rezaeian, Ali Soroush, Mahnaz Ghowsi, Alireza Khatony","doi":"10.1155/sci5/2960393","DOIUrl":"10.1155/sci5/2960393","url":null,"abstract":"<p><p>Recent evidence highlights a concerning increase in fast food consumption among university students. This study aimed to assess the prevalence and determinants of fast food consumption among medical sciences students in Kermanshah, Iran. A cross-sectional study was conducted involving 300 students selected through the stratified random sampling technique. Data were collected using a structured questionnaire and a personal information form. Statistical analysis was performed using SPSS Version 18, applying both descriptive and inferential statistics, including an adjusted Poisson regression model to identify factors associated with fast food consumption. The findings showed that the prevalence of fast food consumption in the past week was 55.7%. Significant determinants included age (incidence rate ratio [IRR] = 1.51, 95% confidence interval [CI] = 1.09-2.09, and <i>p</i> = 0.012) and education level (IRR = 0.85, 95% CI = 0.75-0.97, and <i>p</i> = 0.018). No significant associations were found between fast food consumption and gender, marital status, or body mass index. The high prevalence of fast food consumption among these students raises important health concerns, reflecting unhealthy eating behaviors. Therefore, educating students about the benefits and risks of fast food consumption is essential. Moreover, improving access to healthy and nutritious food options is crucial to reduce dependence on fast food.</p>","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":"2026 ","pages":"2960393"},"PeriodicalIF":3.6,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12856062/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146107091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transforming Epilepsy Care: A Comprehensive Review of Technological Innovations, Artificial Intelligence Advancements, and Precision Tools for Enhanced Seizure Management and Patient Outcomes.","authors":"Mukul Shyam, Naincy Kaushal, Manish Yadav, Prathap Srirangan, Sabina Evan Prince","doi":"10.1155/sci5/5915062","DOIUrl":"10.1155/sci5/5915062","url":null,"abstract":"<p><p>Epilepsy is a neurological disorder characterized by repeated, unprovoked seizures arising from abnormal electrical activity in the brain. The management of epilepsy presents several significant challenges. One of these challenges involves drug resistance, where seizures persist despite treatment with multiple antiepileptic drugs, requiring a tailored approach often involving complex medication regimens or alternative therapies. Additionally, antiepileptic medications can cause a range of side effects, from minor discomfort to severe complications, which can affect patient adherence and overall well-being. Accurate classification and diagnosis of seizures are crucial yet complex, potentially resulting in misdiagnosis and inappropriate treatments. These challenges can be addressed through the utilization of medical devices. A comprehensive assessment of medical apparatuses is utilized in the management of epilepsy, focusing on both implanted and non-invasive technologies. This examination encompasses implanted devices, such as neuromodulators, which are surgically inserted to address seizures in individuals with epilepsy who are resistant to pharmaceutical treatment, as well as noninvasive devices, including wearable technologies and mobile applications. These noninvasive devices enhance seizure detection and monitoring by leveraging advancements in electroencephalography, allowing for real-time data collection. Consequently, there has been an improvement in diagnostic precision and the facilitation of tailored treatment approaches.</p>","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":"2026 ","pages":"5915062"},"PeriodicalIF":3.6,"publicationDate":"2026-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12854098/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146107035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Volume Paradox: Comparing Different Formulas for Estimating the Wood Volume of Trees and Logs in Nepal.","authors":"Pawan Karki, Shambhu Dangal, Edwin Cedamon","doi":"10.1155/sci5/4884890","DOIUrl":"10.1155/sci5/4884890","url":null,"abstract":"<p><p>Accurate estimation of tree and log volume plays a pivotal role in a wide range of applications within the field of forestry, especially in biomass assessment and forest management. The effectiveness and applicability of formulas for volume estimation have recently become a topic of extensive deliberation among forestry officials and a diverse array of stakeholders. This study conducts a comparative analysis between the Huber and allometric equation with the Quarter girth formula and a formula based on form factor to estimate the volume of standing trees and logs. Field measurements of 168 felled trees in coupes and randomly selected 1192 logs were examined in this study. The findings of the study revealed a decrease of approximately 0.8% in timber volume and a substantial increase of 78.6% in firewood volume while adopting the allometric equation when compared to the formula based on form factor. Similarly, the application of Huber's formula resulted in a 27.34% increase in volume compared to the Quarter girth formula. ANOVA demonstrated highly significant differences in the average volume per tree among the four formulas (<i>p</i> value = 0.00004) for both standing tree and log volume, and further analysis using Tukey's HSD indicated that the Quarter girth and form factor-based formula for standing trees differed significantly from the allometric equation for standing timber, while other formula combinations did not show significant differences. Timber losses in the felling and bucking stage with the Quarter girth and Huber formula were 37.06% and 19.86%, respectively. Moreover, paired <i>t</i>-test at 5% level of significance revealed that there was a significant loss in both tree felling using both formulas.</p>","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":"2026 ","pages":"4884890"},"PeriodicalIF":3.6,"publicationDate":"2026-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12820573/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146030777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mineral Composition, Physicochemical Characteristics, and Antioxidant and Antibacterial Properties of Oil Extracted From Moroccan Bitter Apricot Kernels.","authors":"Mohamed Amine El Hajjaji, Kawtar Fikri-Benbrahim, Najoua Soulo, Younesse El-Byari, Zineb Benziane Ouaritini","doi":"10.1155/sci5/7461290","DOIUrl":"10.1155/sci5/7461290","url":null,"abstract":"<p><p>Apricot kernels, often regarded as by-products, are a valuable source of oils and bioactive compounds such as polyphenols, which have applications in pharmacology, the food industry, and cosmetology. This study aimed to address the research gaps regarding the nutritional and functional potential of Moroccan bitter apricot kernels (BAKs) by analyzing their mineral composition and evaluating the physicochemical, antioxidant, and antibacterial properties of their oil. The mineral composition of the kernels was analyzed using ICP-AES. The physicochemical properties of BAK oil, including density (D), acid value (AV), saponification number (SN), iodine value (IV), refractive index (RI), and peroxide value (PV), were evaluated. The total phenolic content (TPC) and total flavonoid content (TFC) were estimated using the Folin-Ciocalteu and aluminum chloride colorimetric methods, respectively. The antioxidant potential was examined through 2,2'-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging and total antioxidant capacity (TAC) assays, and antibacterial activity was evaluated using disc diffusion and microdilution methods. Results showed that the apricot kernels are rich in essential minerals, with high amounts of potassium (184.75 ± 5.5 g/kg) and phosphorus (109.72 ± 2.5 g/kg). The physicochemical properties of the studied oil were as follows: D: 0.92 ± 0.001 g/cm³, AV: 0.65 ± 0.17 mg KOH/g of oil, SN: 187.15 ± 0.05 mg KOH/g of oil, IV: 95.5 ± 0.45 g I₂/100 g of oil, RI: 1.470 ± 0.001, and PV: 0.98 ± 0.17 meq O₂/kg of oil. The total phenolic and flavonoid contents were 41 ± 0.5 mg GAE/100 g and 23.1 ± 0.2 mg QUE/100 g of oil, respectively. The DPPH IC₅₀ value was 6640 ± 0.32 μg/mL, and the TAC was 2.21 ± 0.12 mg AAE/g of oil. The highest antibacterial effect was observed against both Gram-positive bacterial strains, with a MIC value of 100 μL/mL. This study demonstrates that BAKs are a noteworthy oil source, offering promising opportunities for applications in the food and pharmaceutical industries.</p>","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":"2026 ","pages":"7461290"},"PeriodicalIF":3.6,"publicationDate":"2026-01-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12816161/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146019590","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Efficacy of Wood Ash and Leaf Powder of <i>Aquaria salicifolia</i> Against <i>Sitophilus zeamais</i> and <i>Acanthoscelides obtectus</i>.","authors":"Bertilla Beizuh Bua, Jean Wini Goudoungou, Katamssadan Tofel Haman, Daniel Kosini, Raoul Borkeum Barry, Elias Nchiwan Nukenine","doi":"10.1155/sci5/8531268","DOIUrl":"10.1155/sci5/8531268","url":null,"abstract":"<p><p>Maize and beans are very important sources of proteins and carbohydrates, and these grains are widely cultivated and stored for further use and consumption. During their storage, maize and beans are seriously attacked by beetle pests, namely, <i>Sitophilus zeamais</i> and <i>Acanthoscelides obtectus,</i> respectively. The pest management of these beetles is mostly carried out by the use of chemical insecticides, which are not environmentally friendly. In this regard, the insecticidal efficacy of <i>Aquaria salicifolia</i> leaf powder and wood ash was assessed on <i>S. zeamais</i> and <i>A. obtectus</i> concerning their effects on adult mortality, progeny inhibition, repellence, population increase and grain damage in the fluctuating laboratory conditions. Each biosubstance was mixed with grain at different contents (5, 10, 20 and 40 g/kg). Mortality was determined for 1, 3, 7, 10 and 14 days post-treatment. All treatments were displayed on the shelves in the darkness. Four repetitions were carried out for each test, and the experiment was done in a complete randomized block design. The substances significantly caused mortality in the study coleopteran compared to the negative control, with wood ash being more effective than the leaf powder. 40 g/kg of wood ash caused 100% mortality to the bruchids after 10 days of exposure, while 40 g/kg of leaf powder caused 100% mortality after 14 days of exposure. For the weevils, the leaf powder was less effective as the highest dosage causing 37.50% in 14 days whereas wood ash caused 73.75% mortality in the same period. The production of F₁ progeny and rate of population increase as well as percentage of damaged grains and weight losses were reduced significantly by both substances, which were also repellent. Considering these findings, <i>A. salicifolia</i> products could favourably be used as an alternative to chemically synthesized insecticides employed in the conservation of maize and beans during storage.</p>","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":"2026 ","pages":"8531268"},"PeriodicalIF":3.6,"publicationDate":"2026-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12811400/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145999076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}