Scientifica最新文献

{"title":"Population Structure and Regeneration Status of Woody Plant Species in Tulu Korma Dry Afromontane Forest, West Shewa Zone, Oromia, Ethiopia.","authors":"Diriba Deressa,&nbsp;Meseret C Egigu,&nbsp;J M Sasikumar","doi":"10.1155/2023/9964663","DOIUrl":"https://doi.org/10.1155/2023/9964663","url":null,"abstract":"<p><p>A study was conducted on <i>Tulu Korma</i> afromontane forest to assess woody plant species' population structure and natural regeneration status. Data were collected from 52 main quadrats of 400 m² for mature woody species and 260 subplots of 25 m² for seedlings and saplings. All live woody plant species were recorded with their densities, heights, and DBH. Frequency, basal area, importance value, and Shannon-Wiener diversity indices were computed. A total of 101 species that belonged to 45 families were documented. Diversity and evenness indices were 3.44 and 0.7, respectively. Combined density of woody species of all developmental stages was 4971 stems ha^-1 of which 39, 32, and 28% were with DBH < 3.5 cm (seedlings), between 2 and 10 cm (saplings), and >10 cm (mature wordy species), respectively. The total basal area of individuals with DBH ≥ 3.5 cm was 116.18 m² ha^-1. <i>Olea europaea</i> and <i>Podocarpus falcatus</i> were the most dominant species. About 41.58% of the species had IVI < 1. Population structure based on combined densities revealed that density of seedling > sapling > mature individuals, suggesting healthy population structure and good regeneration. On individual basis, however, species showed different patterns of population structure of which 12, 51, and 37% species showed good, fair, and poor regenerations, respectively. Species with least IVI and poor regeneration should be given conservation priority.</p>","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":"2023 ","pages":"9964663"},"PeriodicalIF":3.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10139819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9391499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporomandibular Disorders among Dental Students in Pakistan: Assessment of Prevalence, Severity, and Associated Factors Based on Questionnaire.","authors":"Muhammad Ashraf Nazir,&nbsp;Faisal Izhar,&nbsp;Shafia Hassan,&nbsp;Maha Tanvir,&nbsp;Faris Nemat,&nbsp;Muhammad Waleed Ashraf,&nbsp;Abdulaziz Alamri","doi":"10.1155/2023/8895544","DOIUrl":"https://doi.org/10.1155/2023/8895544","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the prevalence, severity, and associated factors of temporomandibular disorder (TMD) among dental students.</p><p><strong>Methods: </strong>This cross-sectional study was performed on undergraduate dental students from four dental colleges in Punjab, Pakistan. Fonseca's questionnaire was used to measure the prevalence and severity of the TMD among the study participants. Bivariate and multiple logistic regression analyses were performed.</p><p><strong>Results: </strong>Of 364 dental students, 323 returned the completed questionnaires and the response rate of the study was 88.7%. The study included 52.6% males and 47.4% females. The prevalence of TMD was 66.9% with mild TMD in 40.90%, moderate TMD in 14.6%, and severe TMD in 11.50% of the participants. Psychological stress (29.6%), malocclusion (20%), and hypersensitivity (19.5%) were common among participants. The mean TMD score of the sample was 31.54 ± 24.86 which was significantly higher among participants with no/school-educated mothers (<i>P</i>=0.021) and fathers (<i>P</i>=0.002). The participants with arthritis (72.81 ± 32.19) and malocclusion (59.46 ± 31.09) and those who received orthodontic treatment (53.21 ± 34.21) demonstrated higher TMD. After controlling for other study variables, the participants with arthritis were 4.71 times more likely to have moderate/severe TMD (<i>P</i>=0.042) than those without arthritis. Similarly, the participants with malocclusion had significantly higher odds (OR = 3.57, <i>P</i>=0.029) of having moderate/severe TMD than those without malocclusion.</p><p><strong>Conclusion: </strong>This sample of dental students demonstrated a high prevalence and severity of TMD. The participants with arthritis and malocclusion demonstrated higher TMD. The study findings underscore the importance of prevention, early diagnosis, and management of TMD among the dental students.</p>","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":"2023 ","pages":"8895544"},"PeriodicalIF":3.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10368500/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9885097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical Profiles and Anticancer Effects of <i>Calophyllum inophyllum</i> L. Extract Relating to Reactive Oxygen Species Modulation on Patient-Derived Cells from Breast and Lung Cancers.","authors":"Jetsada Ruangsuriya,&nbsp;Jirapast Sichaem,&nbsp;Apichat Tantraworasin,&nbsp;Somcharoen Saeteng,&nbsp;Phanchaporn Wongmaneerung,&nbsp;Angkhana Inta,&nbsp;Neal M Davies,&nbsp;Kewalin Inthanon","doi":"10.1155/2023/6613670","DOIUrl":"https://doi.org/10.1155/2023/6613670","url":null,"abstract":"<p><p>Reactive oxygen species (ROS) contribute to cancer growth and metastasis. Using antioxidants to modulate cellular ROS levels is a promisingstrategy for cancer prevention and treatment. <i>Calophyllum inophyllum</i> L., or tamanu, is a medicinal plant renowned for its anti-inflammatory, antioxidant, and anticancer properties in traditional medicine systems. However, the anticancer effects of <i>C. inophyllum</i> extract on cellular ROS remain unexplored. This study represents the first report on such effects and provides the potential mechanisms underlying the anticancer properties of <i>C. inophyllum</i> extract. The branches of <i>C. inophyllum</i> were extracted, and the extract was comprehensively analyzed for phytochemical constituents, antioxidant capacity, total phenolic content, and total flavonoid content. Subsequently, the extract's potential anticancer properties were evaluated using patient-derived cells from breast and lung cancer. The results revealed that the <i>C. inophyllum</i> extract possesses notable antioxidant activity and demonstrated no cytotoxicity within the initial 24 h of treatment. However, after 72 h, it exhibited significant antiproliferative effects. Moreover, the extract exhibited inhibitory properties against migration and invasion at concentrations below the IC₅₀, which corresponded to the expression of related genes. Notably, these effects correlated with the reduction of intracellular ROS levels. Overall, our findings highlight the anticancer potential of <i>C. inophyllum</i> extract, emphasize its ability to modulate cellular ROS levels and target key molecular pathways involved in cancer progression. This study sheds light on the promising therapeutic implications of <i>C. inophyllum</i> extract as a novel agent for cancer treatment, which is safe for normal cells.</p>","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":"2023 ","pages":"6613670"},"PeriodicalIF":3.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10374377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9906251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Electronic Cigarettes in Dental Caries: A Scoping Review.","authors":"Sumit Gaur,&nbsp;Rupali Agnihotri","doi":"10.1155/2023/9980011","DOIUrl":"https://doi.org/10.1155/2023/9980011","url":null,"abstract":"<p><p>Dental caries, a predominant childhood and adolescence affliction, has numerous factors implicated in its pathogenesis. Electronic cigarettes (ECs) have recently gained popularity among the younger population. Various factors, such as the EC liquid composition and aerosols, are associated with the development of dental caries. This review explains numerous EC-related factors which may lead to dental caries. An electronic search was conducted in Medline (Pubmed), Scopus, and Embase databases to evaluate the original research investigating the role of ECs in developing dental caries. About 12 included studies in the review indicated that factors such as the composition of e-liquids and aerosols are significant in the progression of dental caries. Specifically, cariogenic sugars such as sucrose, fructose, glucose, aldehydes, and flavors such as menthol, cinnamon, and strawberry in the e-liquids contribute to dental caries. They are toxic to oral commensals such as <i>Streptococcus gordonii</i>, <i>Streptococcus mitis</i>, <i>Streptococcus intermedius</i>, and <i>Streptococcus oralis</i> and promote the proliferation of cariogenic pathogens such as <i>Streptococcus mutans</i> (<i>S. mutans</i>) which causes dental caries. However, further validation of the effects of ECs on the development of dental caries is warranted through clinical trials.</p>","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":"2023 ","pages":"9980011"},"PeriodicalIF":3.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10482527/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10192520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Species Composition, Structure, and Regeneration Status of Woody Plants and Anthropogenic Disturbances in Zijje Maryam Church Forest, Ethiopia.","authors":"Amare B Mekonnen, Wubetie A Wassie, Habtemaryam Ayalew, Berhane G Gebreegziabher","doi":"10.1155/2022/8607003","DOIUrl":"10.1155/2022/8607003","url":null,"abstract":"<p><p>Our current study was conducted in Zijje Maryam Church Forest, Ethiopia, to explore woody species composition, structure, regeneration status, and anthropogenic disturbances inside the sacred groves. The aforementioned information for adequate conservation and management of the church forest is not well documented. Fifteen main quadrats each having an area of 625 m² (25 m × 25 m) were used for vegetation and disturbance data collection. Determination of the sampled quadrats was based on the principle that minimum quadrats give the smallest possible area in which all species occurring in the church forest are present. All woody species with a diameter at breast height (DBH) ≥ 2.5 cm within the quadrat were identified, counted, and their height and DBH data were recorded. The criterion to start at DBH ≥ 2.5 cm was to exclude seedlings having DBH < 2.5 cm and height ≤0.6 m. Sapling and seedling data were collected using 45 saplings and 45 seedling quadrat that measured 4 m² and 1 m², respectively. Vegetation data analysis and ANOVA were used for statistical comparison. A total of 48 woody plant species belonging to 46 genera and 36 families were identified. <i>Fabaceae</i> was the dominant family containing 5 species followed by <i>Rosaceae</i> with 3 species. Total basal area of the church forest was 83.03 m² ha^-1. The density of seedlings, saplings, and matured woody species stem ha^-1 were 15555, 3833, and 865, respectively. Talking these densities, the regeneration status of the forest was good. The Shannon diversity and evenness of woody plant species in the forest was high, 3.29 and 0.85, respectively. <i>Juniperus procera</i> 27.67 (9.22%) and <i>Olea europaea</i> were species with the highest IVI. Nearly, 22% of areas of the forest get disturbed and higher anthropogenic disturbances occurred near the edge of the forest. Gathering, clearing, and grazing are the major human disturbances that stakeholders need to tackle for conservation. Zijje Maryam Church Forest has heterogeneous species composition with varied seedlings and saplings. Therefore, local conservation policies recommended not only protect large forests, but also the small and valuable forests service to the needs of local people.</p>","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":"2022 ","pages":"8607003"},"PeriodicalIF":2.3,"publicationDate":"2022-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9733990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10323505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of the Status of Rooftop Garden, Its Diversity, and Determinants of Urban Green Roofs in Nepal","authors":"S. Rawal, S. Thapa","doi":"10.1155/2022/6744042","DOIUrl":"https://doi.org/10.1155/2022/6744042","url":null,"abstract":"In recent days, the practice of adopting rooftop garden can be seen in urban areas of developing countries, but a successful adoption of well-equipped green roofs is still lacking and is limited to open farms. To fulfill the gaps in urban agriculture in determining diversity status and socioeconomic factors affecting the adoption of RTG, this study was conducted. The survey was conducted from February 3 to April 6, 2021, where a total of 116 respondents were selected randomly from Morang and Sunsari districts. The rooftop adopters had 30.5% and 33.2% of the roofs under farming in Morang and Sunsari, respectively, having the size of the roof of rooftop adopters significantly larger than nonadopters. A binary logit model was used to determine the factor affecting the adoption of RTG where age, gender, schooling year, training, and farming experience have a significant effect on the adoption of RTG. Locally available material was given preference under farming and nutritionally important 50 species were reported with tests of the daily food requirement of the respondents. The diversity indices suggest that ornamental plant diversity is more followed by vegetables. Though, adopters are continuing the garden but have reported that lack of proper policy and ineffective management makes it difficult to protect the life of roof. Concludingly, respondents and other willing people must be provided with training, financial support, and proper extension services as lack of training and extension services are the major problems reported in the study area. Proper policy of rooftop garden is lacking in study area though it is under study in Kathmandu; thus, policy makers and research institution should focus on promoting the rooftop in study area and provide more reliable package for roof protection and garden continuation.","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2022-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42529508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microencapsulation of Ruellia tuberosa L. Aqueous Root Extracts Using Chitosan-Sodium Tripolyphosphate and Their In Vitro Biological Activities","authors":"A. Safitri, A. Roosdiana, N. Kurnianingsih, F. Fatchiyah, Eldina Mayasari, Rina Rachmawati","doi":"10.1155/2022/9522463","DOIUrl":"https://doi.org/10.1155/2022/9522463","url":null,"abstract":"The current study aims to perform microencapsulation of R. tuberosa L. extracts using chitosan crosslinked to sodium tripolyphosphate (NaTPP) as wall materials by spray drying and to analyze their in vitro biological activities. The influence of manufacturing conditions, like pH, chitosan concentration, and stirrer time, was assessed. Results showed that microcapsules prepared in pH 4 with a concentration of 0.1% (w/v) chitosan, and 90 min stirring time had 51.80% encapsulation efficiency and high in vitro biological activity. These were shown by high in vitro alpha amylase inhibition and antioxidant activity with IC50 values of 50.65 μg/mL and 123.97 μg/mL, respectively. Releases of the bioactive compounds in microcapsules of R. tuberosa L. were carried out on phosphate buffer medium pH 2.2 and pH 7.4 with times release of 30, 60, 90, and 120 min. The bioactive compounds were released in pH 2.2 in 120 min at 2.48%. At pH 7.4, the active ingredients were more easily released, by 79.90% in 120 min. The microcapsules' morphology showed a rough surface with spherical forms and the average sizes were 53.41 μm. This study supports the essential role of microencapsulation in improving plant extracts with reserved biological activities.","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2022-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41809893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Green Biosynthesis of Silver Nanoparticles Using Malva parviflora Extract for Improving a New Nutrition Formula of a Hydroponic System","authors":"A. G. Oraibi, H. N. Yahia, K. H. Alobaidi","doi":"10.1155/2022/4894642","DOIUrl":"https://doi.org/10.1155/2022/4894642","url":null,"abstract":"There are increasing needs for developing nontoxic, low-cost, high-yield, and eco-friendly procedures for manufacturing nanoparticles. Nanobiotechnology can be used in food security for improving crop production; nanoparticles could enhance the growth and yield of different crop plants; therefore, this work aimed to improve a new nutrition formula of a hydroponic system using green biosynthesis of silver nanoparticles and Malva parviflora aqueous extract. Results shown that AFM image of AgNP surface morphology provides good indicator for biosynthesizing AgNPs. UV-vis spectroscopy showed the presence of silver elements that proved the reduction of silver ion to an element in the presence of plant extract functional groups which act as a reduction reaction capping agent. AgNPs formation from 1 mM of AgNo3 and Malva parviflora filtrate can easily be characterized through visual observations by the change in the color of the reaction mixture from green to yellowish-brown. SEM showed that most of the Ag nanoparticles were spherical in shape, well dispersed, and were either arranged in clusters of particles with each other, or as small particles, and have been identified in a size range of 12–63 nm. The EDX characterization exhibited that the highest proportion of the element composition was for silver weighting (34.11%) in nanoparticle. Other elements such as aluminum (12.28%), carbon (8.62%), hafnium (18.12%), nitrogen (9.34%), sodium (10.01%), and oxygen (7.52%) may arise from Malva parviflora extract. Also, peroxidase and catalase enzyme activity, cabbage crop seedlings, fresh and dry weights, and proline and carbohydrate concentrations were significantly increased with the increase of biosynthesized AgNP concentrations but up to limit.","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2022-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43856231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Secondary Metabolism Gene Diversity and Cocultivation toward Isolation and Identification of Potent Bioactive Compounds Producing Bacterial Strains from Thailand's Natural Resources","authors":"Suranat Phonghanpot, F. Jarintanan","doi":"10.1155/2022/2827831","DOIUrl":"https://doi.org/10.1155/2022/2827831","url":null,"abstract":"Thailand was proposed to be rich unexplored source of microorganisms, especially bacterial strains. There should be bacteria with high secondary metabolite production potential in the natural resources that are still unidentified. Moreover, they might not produce secondary metabolites in standard laboratory culture condition after isolation, in which coculture condition would help us pursuing the bacteria to produce bioactive metabolites. Here, we aimed to identify new bacterial strains with high secondary metabolite production potential from Thailand's natural resources. To achieve the goal, we performed bacteria isolation, phylogenetic analysis, degenerate PCR of secondary metabolism genes, cocultivation, antibacterial analysis, and HPLC chemical profiling. We isolated distinct 40 bacterial strains, which have over 98% 16S rRNA sequence similarity with known species. There were 22, 31, and 29 strains giving positive PCR amplification of NRPS, PKS, and TPS genes, respectively. Among them, Bacillus licheniformis RSUCC0101 had the highest number of PCR products, 26. In standard single culture condition, crude extracts prepared from Bacillus safensis RSUCC0021 and Bacillus amyloliquefaciens RSUCC0282 could inhibit the growth of Staphylococcus aureus ATCC25923. Furthermore, the cocultivation and HPLC analyses showed that the extracts prepared from 3 pairs of culture between Staphylococcus sp. RSUCC0020, Micrococcus luteus RSUCC0053, Staphylococcus sp. RSUCC0087, and Staphylococcus pasteuri RSUCC0090 could inhibit the growth of Staphylococcus aureus ATCC25923 and produced distinct chemical profiles from their single culture condition. Our study led to the isolation and identification of several promising bacterial strains for production of secondary metabolites that might be useful in biomedical applications.","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2022-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49166721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don","authors":"Minhajur Rahman, Abu Taleb Surag, Roxy Begum, Md. Shakhuat Hossain Tusher, M. K. Huda","doi":"10.1155/2022/5660527","DOIUrl":"https://doi.org/10.1155/2022/5660527","url":null,"abstract":"For the first time, Cleisomeria lanatum (family: Orchidaceae) has been investigated for its phytochemical, antioxidant, anti-inflammatory, and thrombolytic properties. All phytochemicals studied were identified in varying degrees during qualitative screening. In quantitative screening, a maximum of 106.02 ± 0.08 mg/g alkaloids (root), 179.67 ± 8.83 mg/g phenols (stem), 17.34 ± 0.88 mg/g flavonoids (stem), 73.67 ± 1.76 mg/g tannins (stem), and 180.04 ± 0.02 μg/mL proteins (root) were detected. Antioxidant, anti-inflammatory, and thrombolytic properties were investigated using a free-radical scavenging assay, heat-induced albumin denaturation assay, and blood clotting inhibition assay. The root extracts had the most effective antioxidant (IC50 = 67.98 μg/mL) and anti-inflammatory (IC50 = 60.86 μg/mL) properties, whereas the stem extracts had the most effective thrombolytic property (IC50 = 163.8 μg/mL). The bioactivities studied also had a significant positive relationship (r = 0.9; p  <  0.05) with the amount of phenolics and tannins.","PeriodicalId":21726,"journal":{"name":"Scientifica","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2022-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47429074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}