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Effects of stevia consumption on appetite in adults: A systematic review and dose-response meta-analysis of randomized controlled trials.
IF 8 2区 医学
Obesity Reviews Pub Date : 2025-01-30 DOI: 10.1111/obr.13902
Marzieh Zare, Mobina Zeinalabedini, Soraiya Ebrahimpour-Koujan, Leila Azadbakht
{"title":"Effects of stevia consumption on appetite in adults: A systematic review and dose-response meta-analysis of randomized controlled trials.","authors":"Marzieh Zare, Mobina Zeinalabedini, Soraiya Ebrahimpour-Koujan, Leila Azadbakht","doi":"10.1111/obr.13902","DOIUrl":"https://doi.org/10.1111/obr.13902","url":null,"abstract":"<p><p>Stevia is an intense, calorie-free sweetener that is frequently used to reduce energy intake; however, studies examining its effects on appetite and energy intake have produced mixed results, indicating that a definitive consensus has not yet been reached. This systematic review and meta-analysis aimed to determine the impact of stevia on appetite and energy intake in adults. The PROSPERO registration number for this research is CRD42023414411. The databases PubMed (MEDLINE), Scopus, Web of Science, and Google Scholar were systematically searched. In addition, the reference lists of extracted articles and pertinent reviews were examined. Two evaluators performed screening, quality assessment, and data extraction independently. Furthermore, the GRADE (Grading of Recommendations, Assessment, Development, and Evaluation) approach was employed to systematically assess the certainty level of the evidence presented in our study. Eleven clinical trials with a total of 428 participants were included. We found no significant changes in any appetite scores following stevia consumption (very low to moderate certainty of the evidence). Moreover, subgroup analyses demonstrated the scores of desires to eat increased significantly in the oral intake of stevia and not enteral intake subgroup (WMD: 0.45; 95% CI: 0.009, 0.89; P = 0.046). In addition, the number of studies reporting energy intake was limited, preventing a meta-analysis of this variable. In conclusion, stevia consumption has no significant effect on appetite scores in adults but it seems that more long-term clinical trials are needed to obtain more accurate results. PRACTITIONER POINT: Stevia, as a non-nutritive sweetener, has no significant effect on appetite scores in adults.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":" ","pages":"e13902"},"PeriodicalIF":8.0,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143062695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plant-based and sustainable diet: A systematic review of its impact on obesity.
IF 8 2区 医学
Obesity Reviews Pub Date : 2025-01-29 DOI: 10.1111/obr.13901
Sara P Mambrini, Claudia Penzavecchia, Francesca Menichetti, Andrea Foppiani, Alessandro Leone, Marta Pellizzari, Federica Sileo, Alberto Battezzati, Simona Bertoli, Ramona De Amicis
{"title":"Plant-based and sustainable diet: A systematic review of its impact on obesity.","authors":"Sara P Mambrini, Claudia Penzavecchia, Francesca Menichetti, Andrea Foppiani, Alessandro Leone, Marta Pellizzari, Federica Sileo, Alberto Battezzati, Simona Bertoli, Ramona De Amicis","doi":"10.1111/obr.13901","DOIUrl":"https://doi.org/10.1111/obr.13901","url":null,"abstract":"<p><p>The food system significantly affects the environment through land use, emissions from livestock, deforestation, and food waste. Diet sustainability considers the environmental effects of food production, distribution, and consumption. Animal products emit more greenhouse gases than plant-based foods, prompting a shift towards plant-focused diets for reduced emissions. Sustainable diets, like the EAT-Lancet model, prioritize plant-based foods, adjusting for regional eating habits. These diets aim to be both environmentally friendly and conducive to human health, addressing concerns like obesity and chronic diseases. Obesity is a major global health challenge, and its complex relationship with food production and consumption patterns calls for sustainable solutions to reduce pressure on ecosystems and promote healthier lifestyles. Tackling obesity requires holistic strategies that address not only individual health but also the broader environmental impacts of food systems. A systematic review examined the link between plant-based diets and obesity focusing on studies assessing Body Mass Index (BMI) and body fat assessment. Despite limited research, evidence suggests that adherence to a plant-based diet, particularly a healthy one, is associated with lower obesity rates. More longitudinal and intervention studies are necessary for a stronger consensus on the matter.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":" ","pages":"e13901"},"PeriodicalIF":8.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143062788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A best practice guide for conducting healthy food retail research: A resource for researchers and health promotion practitioners
IF 8 2区 医学
Obesity Reviews Pub Date : 2025-01-29 DOI: 10.1111/obr.13870
Tailane Scapin, Tara Boelsen-Robinson, Shaan Naughton, Jaithri Ananthapavan, Miranda Blake, Megan Ferguson, Clara Gomez-Donoso, Adyya Gupta, Victoria Hobbs, Emma Joy McMahon, Helena Romaniuk, Gary Sacks, Julia Thompson, Laura Alston, Kathryn Backholer, Rebecca Bennett, Julie Brimblecombe, Jasmine Chan, Katrine S. Duus, Oliver Huse, Damian Maganja, Josephine Marshall, Liliana Orellana, Emalie Rosewarne, Sally Schultz, Katherine Sievert, Simone Sherriff, Huong Ngoc Quynh Tran, Carmen Vargas, Jason H. Y. Wu, Anna Peeters, Adrian J. Cameron
{"title":"A best practice guide for conducting healthy food retail research: A resource for researchers and health promotion practitioners","authors":"Tailane Scapin,&nbsp;Tara Boelsen-Robinson,&nbsp;Shaan Naughton,&nbsp;Jaithri Ananthapavan,&nbsp;Miranda Blake,&nbsp;Megan Ferguson,&nbsp;Clara Gomez-Donoso,&nbsp;Adyya Gupta,&nbsp;Victoria Hobbs,&nbsp;Emma Joy McMahon,&nbsp;Helena Romaniuk,&nbsp;Gary Sacks,&nbsp;Julia Thompson,&nbsp;Laura Alston,&nbsp;Kathryn Backholer,&nbsp;Rebecca Bennett,&nbsp;Julie Brimblecombe,&nbsp;Jasmine Chan,&nbsp;Katrine S. Duus,&nbsp;Oliver Huse,&nbsp;Damian Maganja,&nbsp;Josephine Marshall,&nbsp;Liliana Orellana,&nbsp;Emalie Rosewarne,&nbsp;Sally Schultz,&nbsp;Katherine Sievert,&nbsp;Simone Sherriff,&nbsp;Huong Ngoc Quynh Tran,&nbsp;Carmen Vargas,&nbsp;Jason H. Y. Wu,&nbsp;Anna Peeters,&nbsp;Adrian J. Cameron","doi":"10.1111/obr.13870","DOIUrl":"10.1111/obr.13870","url":null,"abstract":"<p>Retail food environments play a pivotal role in influencing dietary behaviors, and therefore have huge potential as settings for promoting good nutrition and preventing obesity. Conducting research in retail settings can be challenging due to the varied motivations of the parties involved and the complex nature of retail environments. To improve the quality and consistency of research in this field, we have identified 16 thematic topics aimed at guiding researchers and public health practitioners on how to conduct healthy food retail research. A summary for each topic, encompassing existing methodologies, best practice examples, and knowledge gaps, was developed based on available literature and the collective experience and expertise of 32 multidisciplinary researchers from a high-income perspective engaged in healthy food retail research in a diverse range of retail settings. A summary checklist describing key considerations at each stage of conducting healthy food retail research was also developed.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 4","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/obr.13870","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143062755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the progress and trends of immunotherapy for type 1 diabetes: A comprehensive bibliometric analysis spanning nearly two decades
IF 8 2区 医学
Obesity Reviews Pub Date : 2025-01-28 DOI: 10.1111/obr.13888
Yixin Jiang, Zhou Xu, Yuting Wu, Xinglei Li, Jitao Ling, Yixuan Chen, Zicheng Zhu, Pingping Yang, Xiao Liu, Deju Zhang, Jianping Liu, Xiaoping Yin, Jing Zhang, Peng Yu
{"title":"Exploring the progress and trends of immunotherapy for type 1 diabetes: A comprehensive bibliometric analysis spanning nearly two decades","authors":"Yixin Jiang,&nbsp;Zhou Xu,&nbsp;Yuting Wu,&nbsp;Xinglei Li,&nbsp;Jitao Ling,&nbsp;Yixuan Chen,&nbsp;Zicheng Zhu,&nbsp;Pingping Yang,&nbsp;Xiao Liu,&nbsp;Deju Zhang,&nbsp;Jianping Liu,&nbsp;Xiaoping Yin,&nbsp;Jing Zhang,&nbsp;Peng Yu","doi":"10.1111/obr.13888","DOIUrl":"10.1111/obr.13888","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Immunotherapy is a crucial treatment for type 1 diabetes (T1D), yet analyses focusing on research priorities and trends in this field are limited. Therefore, this study employs bibliometric methods to systematically explore the current research status of immunotherapy for T1D.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Based on the Web of Science Core Collection Database, 1573 articles and review articles related to immunotherapy for T1D published from 2004 to 2023 were screened for bibliometric analysis. VOSviewer, CiteSpace, and R software were applied to comprehensively analyze the number of publications, journals, countries, authors, institutions, keywords, and references.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In the past two decades, the global annual publication rate has seen a significant increase of 238.24%. Almost 40% of all publications have appeared in the last 5 years, accounting for over 50% of total citations. Journals such as <i>Diabetes, Journal of Autoimmunity</i> and <i>Frontiers in Immunology</i> have exerted substantial influence. Collaboration across nations has been notably strong, with the United States leading the way. The University of Florida is the most productive institution. Terms like “nivolumab,” “ipilimumab,” “pembrolizumab,” and “immune checkpoint inhibitor(s)” gain considerable traction. The majority of research has clustered around themes such as immunomodulation, autoimmune diseases, immune checkpoint inhibitors, mesenchymal stem cells, and cell therapy. Precision medicine, immune checkpoint inhibitors, and nanotechnology are trending focal points in contemporary research.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The outcomes of the study are instrumental in enabling scholars to comprehend the evolving trajectory of immunotherapeutic approaches for T1D and facilitate the swift recognition of emerging research pathways.</p>\u0000 </section>\u0000 </div>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 5","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143051196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nutritional and functional outcomes in trials of nutrient-stimulated hormone-based therapy—A systematic mapping review
IF 8 2区 医学
Obesity Reviews Pub Date : 2025-01-27 DOI: 10.1111/obr.13890
Sébastien Czernichow, Nathalie Rassy, Claire Carette, Nicholas Shoung, Frank B. Hu, Claire Rives-Lange
{"title":"Nutritional and functional outcomes in trials of nutrient-stimulated hormone-based therapy—A systematic mapping review","authors":"Sébastien Czernichow,&nbsp;Nathalie Rassy,&nbsp;Claire Carette,&nbsp;Nicholas Shoung,&nbsp;Frank B. Hu,&nbsp;Claire Rives-Lange","doi":"10.1111/obr.13890","DOIUrl":"10.1111/obr.13890","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Currently, trials are investigating the efficacy of nutrient-stimulated hormone-based therapies (NuSHs) in promoting weight loss in people living with overweight and obesity. However, the extent to which nutritional and functional outcomes are evaluated remains uncertain. Thus, we conducted a systematic mapping to assess the presence of nutritional and functional outcomes in randomized controlled trials (RCTs) investigating NuSHs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted a systematic mapping search on the Cochrane Central Register of Controlled Trials (CENTRAL), which includes ClinicalTrials.gov and the International Clinical Trials Registry Platform for interventional trials of NuSHs registered from inception to December 31, 2023. We excluded non- and quasi-randomized trials, phase I trials, trials that did not include body weight as a primary or secondary outcome, trials with an intervention duration of less than 6 months, and trials that did not specify a body mass index threshold in their eligibility criteria. Outcomes included: dietary intake, eating behavior, body composition, physical performance, muscle strength, bone health, and levels of vitamins, trace elements, albumin, prealbumin, and hemoglobin.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The search identified 2284 trials, of which 417 were included in the analysis. The proportion of RCTs that included nutritional assessment other than body weight increased over time. Approximately, 20.4% reported measurements of body composition, 17.3% reported measurements of albumin/prealbumin/hemoglobin, and 17% reported assessment of dietary intake and eating behavior. Evaluations of bone health, physical performance, muscle strength, and measurements of vitamins/trace elements were reported in less than 5% of the total trials each.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The present review has shown the sparse reporting of nutritional and functional outcomes in RCTs evaluating the impact of NuSHs.</p>\u0000 </section>\u0000 </div>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 5","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-01-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/obr.13890","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143045139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Therapeutic potential of stem cell-derived somatic cells to treat metabolic dysfunction-associated steatotic liver disease and diabetes.
IF 8 2区 医学
Obesity Reviews Pub Date : 2025-01-24 DOI: 10.1111/obr.13899
Eduardo H Gilglioni, Mayank Bansal, Wadsen St-Pierre-Wijckmans, Stephanie Talamantes, Alvile Kasarinaite, David C Hay, Esteban N Gurzov
{"title":"Therapeutic potential of stem cell-derived somatic cells to treat metabolic dysfunction-associated steatotic liver disease and diabetes.","authors":"Eduardo H Gilglioni, Mayank Bansal, Wadsen St-Pierre-Wijckmans, Stephanie Talamantes, Alvile Kasarinaite, David C Hay, Esteban N Gurzov","doi":"10.1111/obr.13899","DOIUrl":"https://doi.org/10.1111/obr.13899","url":null,"abstract":"<p><p>Developments in basic stem cell biology have paved the way for technology translation in human medicine. An exciting prospective use of stem cells is the ex vivo generation of hepatic and pancreatic endocrine cells for biomedical applications. This includes creating novel models 'in a dish' and developing therapeutic strategies for complex diseases, such as metabolic dysfunction-associated steatotic liver disease (MASLD) and diabetes. In this review, we explore recent advances in the generation of stem cell-derived hepatocyte-like cells and insulin-producing β-like cells. We cover the different differentiation strategies, new discoveries, and the caveats that still exist regarding their routine use. Finally, we discuss the challenges and limitations of stem cell-derived therapies as a clinical strategy to manage metabolic diseases in humans.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":" ","pages":"e13899"},"PeriodicalIF":8.0,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143035481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Validity of non-traditional measures of obesity compared to total body fat across the life course: A systematic review and meta-analysis.
IF 8 2区 医学
Obesity Reviews Pub Date : 2025-01-24 DOI: 10.1111/obr.13894
Alexandra M Palumbo, Chandni Maria Jacob, Sahar Khademioore, Mohammad Nazmus Sakib, Yulika Yoshida-Montezuma, Nicolette Christodoulakis, Peter Yassa, Manasvi Sai Vanama, Syrine Gamra, Pei-Ju Ho, Ritu Sadana, Vanessa De Rubeis, Lauren E Griffith, Laura N Anderson
{"title":"Validity of non-traditional measures of obesity compared to total body fat across the life course: A systematic review and meta-analysis.","authors":"Alexandra M Palumbo, Chandni Maria Jacob, Sahar Khademioore, Mohammad Nazmus Sakib, Yulika Yoshida-Montezuma, Nicolette Christodoulakis, Peter Yassa, Manasvi Sai Vanama, Syrine Gamra, Pei-Ju Ho, Ritu Sadana, Vanessa De Rubeis, Lauren E Griffith, Laura N Anderson","doi":"10.1111/obr.13894","DOIUrl":"10.1111/obr.13894","url":null,"abstract":"<p><p>IntroductionTraditional obesity measures including body mass index, waist circumference, waist-to-hip ratio, and waist-to-height ratio have limitations. The primary objective of this study was to identify and review the validity of non-traditional obesity measures, using measures of total body fat as the reference standard, that have been used across multiple life stages. MethodsWe conducted a systematic review and searched MEDLINE, Embase, and PsycINFO. We included observational studies published from 2013 to October 2023 among \"the general population\" for any life stage that reported the validity of non-traditional obesity measures compared to total body fat reference standards. Separate meta-analyses were performed to pool correlation coefficients and mean differences for non-traditional obesity measures that were evaluated at multiple life stages. ResultsA total of 123 studies were included, and 55 validated non-traditional obesity measures were identified. Of these, 13 were evaluated at multiple life stages. Two-dimensional (2D) digital imaging technologies, three-dimensional (3D) body scanners, relative fat mass (RFM), and mid-upper arm circumference had high or moderate validity (pooled correlation coefficient >0.70). Pooled mean differences were small (<6%) between total body fat percentage from reference standards and from RFM, 2D digital imaging technologies, 3D body scanners, and the body adiposity index. Heterogeneity (I<sup>2</sup>) was >75% in most meta-analyses. ConclusionNumerous validated non-traditional obesity measures were identified; relatively few were evaluated at multiple life stages and did not consider health risks associated with adiposity. More research is needed to define valid obesity measures across all life stages that assess health and adiposity.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":" ","pages":"e13894"},"PeriodicalIF":8.0,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143035482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association of iron deficiency and anemia with obesity among children: A systematic review and meta-analysis.
IF 8 2区 医学
Obesity Reviews Pub Date : 2025-01-22 DOI: 10.1111/obr.13892
Meenakshi Sachdeva, Meenakshi Malik, Abhishek Purohit, Lovely Jain, Kulbir Kaur, Pranita Pradhan, Joseph L Mathew
{"title":"Association of iron deficiency and anemia with obesity among children: A systematic review and meta-analysis.","authors":"Meenakshi Sachdeva, Meenakshi Malik, Abhishek Purohit, Lovely Jain, Kulbir Kaur, Pranita Pradhan, Joseph L Mathew","doi":"10.1111/obr.13892","DOIUrl":"https://doi.org/10.1111/obr.13892","url":null,"abstract":"<p><strong>Introduction: </strong>Obesity is a potential risk factor for anemia in children. This systematic review (SR) was undertaken to estimate the association of obesity with iron deficiency (ID) and ID anemia (IDA), in children.</p><p><strong>Methods: </strong>A systematic literature search for observational studies was done in PubMed, EMBASE, Scopus, and the Cochrane library, with additional hand-searching. Two reviewers independently screened the search output, included eligible studies, extracted data, and assessed study quality using the National Institutes of Health tool. The main outcomes were association of obesity with anemia (IDA), and ID. Secondary outcomes were hemoglobin level, serum iron, ferritin, transferrin receptor saturation, and hepcidin. Meta-analysis was done using a random-effects model. Comparisons were expressed through pooled OR with 95% CI.</p><p><strong>Results: </strong>Forty-two studies comprising one cohort, 29 cross-sectional, and 12 case-control studies comparing 16,633 children living with obesity and 32,573 children without obesity were included. The pooled OR (95% CI) for ID was 1.64 (1.22, 2.21), 16 studies, 20,949 children; and 0.78 (0.43, 1.43), 17 studies, 40,022 children, for IDA. The pooled prevalence of ID was 20.07% (14.98, 25.16) among children living with obesity (16 studies, 3147 children), compared to 16.1% (11.82, 20.38) in children without obesity. Children living with obesity had significantly lower levels of hemoglobin, iron, % transferrin saturation, and higher levels of ferritin and hepcidin than children without obesity.</p><p><strong>Conclusion: </strong>There is a significant association between iron deficiency and obesity in children.</p>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":" ","pages":"e13892"},"PeriodicalIF":8.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Behavior change techniques in low-calorie and very low-calorie diet interventions for weight loss: A systematic review with meta-analysis
IF 8 2区 医学
Obesity Reviews Pub Date : 2025-01-22 DOI: 10.1111/obr.13896
Tamla S. Evans, Pooja Dhir, Jamie Matu, Duncan Radley, Andrew J. Hill, Andrew Jones, Lisa Newson, Charlotte Freeman, Katerina Z. Kolokotroni, Therese Fozard, Louisa J. Ells
{"title":"Behavior change techniques in low-calorie and very low-calorie diet interventions for weight loss: A systematic review with meta-analysis","authors":"Tamla S. Evans,&nbsp;Pooja Dhir,&nbsp;Jamie Matu,&nbsp;Duncan Radley,&nbsp;Andrew J. Hill,&nbsp;Andrew Jones,&nbsp;Lisa Newson,&nbsp;Charlotte Freeman,&nbsp;Katerina Z. Kolokotroni,&nbsp;Therese Fozard,&nbsp;Louisa J. Ells","doi":"10.1111/obr.13896","DOIUrl":"10.1111/obr.13896","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>There is limited evidence and clinical guidelines on the behavior change support required for low-calorie diet programs. This systematic review aimed to establish the behavior change technique(s) (BCT) implemented in weight loss interventions (≤1200 kcal/d) and how these contribute to effectiveness.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Databases were searched from inception to April 2022. Screening, data extraction, BCT coding, and quality appraisal were conducted in duplicate using the Template for Intervention Description and Replication framework, Behavior Change Technique Taxonomy, and Cochrane Risk of Bias 2 tool. Data were analyzed via narrative synthesis and random effects multi-level meta-analyses.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Thirty-two papers reporting on 27 studies were included. Twenty-four BCTs were identified across studies. Eight BCTs were significantly associated with a larger reduction in weight at the end-of-diet time-point; one BCT was statistically significant at the end of weight maintenance. Physical activity, Type 2 Diabetes, and BMI category moderated intervention effects.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions and implications</h3>\u0000 \u0000 <p>This is the first meta-analysis to examine how specific BCTs contribute to the effectiveness of low-calorie diets. It is recommended that a) these findings are used to develop clinical guidelines specific to behavioral support in low-calorie diet programs, and b) program commissioners stipulate the use of these BCTs in their service specifications.</p>\u0000 </section>\u0000 </div>","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":"26 5","pages":""},"PeriodicalIF":8.0,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/obr.13896","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143021398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on "adipokines and stroke: A systematic review and meta-analysis of disease risk and patient outcomes". 对“脂肪因子和中风:疾病风险和患者预后的系统回顾和荟萃分析”的评论。
IF 8 2区 医学
Obesity Reviews Pub Date : 2025-01-21 DOI: 10.1111/obr.13900
Lang Li, Xueyang Tang
{"title":"Comment on \"adipokines and stroke: A systematic review and meta-analysis of disease risk and patient outcomes\".","authors":"Lang Li, Xueyang Tang","doi":"10.1111/obr.13900","DOIUrl":"https://doi.org/10.1111/obr.13900","url":null,"abstract":"","PeriodicalId":216,"journal":{"name":"Obesity Reviews","volume":" ","pages":"e13900"},"PeriodicalIF":8.0,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142997112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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