Research Status on the Effects of Obesity on Acute Pancreatitis.

IF 7.4 2区医学 Q1 ENDOCRINOLOGY & METABOLISM

Obesity Reviews Pub Date : 2025-08-02 DOI:10.1111/obr.70007

Dilinigeer Tayier, Kunlei Wang, Yufeng Yuan, Zhiyong Yang

引用次数: 0

Abstract

Acute pancreatitis (AP) is an inflammatory disease characterized by the premature activation of trypsinogen. Mild acute pancreatitis is self-limiting; however, approximately 15-20% of patients progress to severe acute pancreatitis (SAP), which is associated with pancreatic tissue necrosis, systemic inflammatory response syndrome, organ failure, and a mortality rate of up to 30%. Obesity, a growing global public health concern with increasing yearly incidence worldwide, is an established independent risk factor for the development and exacerbation of AP. This review provides a comprehensive summary of the impact of obesity on the increased risk, occurrence, and progression of AP.

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肥胖对急性胰腺炎影响的研究现状

急性胰腺炎是一种以胰蛋白酶原过早激活为特征的炎症性疾病。轻度急性胰腺炎是自限性的；然而，大约15-20%的患者进展为严重急性胰腺炎（SAP），这与胰腺组织坏死、全身炎症反应综合征、器官衰竭和高达30%的死亡率有关。肥胖是一个日益增长的全球公共卫生问题，每年在全球范围内的发病率不断增加，是AP发展和恶化的一个确定的独立危险因素。本综述全面总结了肥胖对AP风险增加、发生和进展的影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Obesity Reviews 医学-内分泌学与代谢

CiteScore

19.30

自引率

1.10%

发文量

130

审稿时长

1 months

期刊介绍： Obesity Reviews is a monthly journal publishing reviews on all disciplines related to obesity and its comorbidities. This includes basic and behavioral sciences, clinical treatment and outcomes, epidemiology, prevention and public health. The journal should, therefore, appeal to all professionals with an interest in obesity and its comorbidities. Review types may include systematic narrative reviews, quantitative meta-analyses and narrative reviews but all must offer new insights, critical or novel perspectives that will enhance the state of knowledge in the field. The editorial policy is to publish high quality peer-reviewed manuscripts that provide needed new insight into all aspects of obesity and its related comorbidities while minimizing the period between submission and publication.