Scandinavian Journal of Urology and Nephrology最新文献_第7页

Five-year progression-free survival in 577 patients operated on with laparoscopic radical prostatectomy for localized prostate cancer. 577例腹腔镜根治性前列腺切除术治疗局限性前列腺癌患者的5年无进展生存率

Scandinavian Journal of Urology and Nephrology Pub Date : 2012-02-01 Epub Date: 2011-08-15 DOI: 10.3109/00365599.2011.604790

Viktor Berge, Rolf Eigil Berg, Jon Roar Hoff, Nicolai Wessel, Aud Svindland, Steinar Johan Karlsen, Lars Magne Eri

{"title":"Five-year progression-free survival in 577 patients operated on with laparoscopic radical prostatectomy for localized prostate cancer.","authors":"Viktor Berge, Rolf Eigil Berg, Jon Roar Hoff, Nicolai Wessel, Aud Svindland, Steinar Johan Karlsen, Lars Magne Eri","doi":"10.3109/00365599.2011.604790","DOIUrl":"https://doi.org/10.3109/00365599.2011.604790","url":null,"abstract":"Objective: Laparoscopic radical prostatectomy (LRP) was introduced in the Department of Urology, Oslo University Hospital, in 2002. The aim of this study was to report mid-term oncology results and survival data.Material and methods: From February 2002 to November 2007, 582 consecutive patients with localized prostate cancer underwent LRP. Data were collected prospectively into a database.Results: Mean and median follow-up after LRP was 30.3 months (± 15.5) and 36.0 months (range 3-72). Five patients (1%) were lost during follow-up. Two patients died of prostate cancer during the study period and 10 patients died of other causes. The overall positive surgical margin (PSM) rate was 29% and decreased to 13% for the last 100 patients. The overall PSA progression-free survival (PFS) was 85% at 3 years and 73% at 5 years. Gleason score in the tumour specimen, pT stage and surgical margins were statistical significant independent predictors of biochemical PFS.Conclusion: These oncology results and 5-year PFS data after LRP are in line with other reports.","PeriodicalId":21543,"journal":{"name":"Scandinavian Journal of Urology and Nephrology","volume":"46 1","pages":"8-13"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00365599.2011.604790","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30079555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Parental experiences and preferences regarding the treatment of vesicoureteral reflux. 父母对膀胱输尿管反流治疗的经验和偏好。

Scandinavian Journal of Urology and Nephrology Pub Date : 2012-02-01 Epub Date: 2011-10-19 DOI: 10.3109/00365599.2011.621144

Tryggve Nevéus, Per Brandström, Tina Linnér, Ulf Jodal, Sverker Hansson

{"title":"Parental experiences and preferences regarding the treatment of vesicoureteral reflux.","authors":"Tryggve Nevéus, Per Brandström, Tina Linnér, Ulf Jodal, Sverker Hansson","doi":"10.3109/00365599.2011.621144","DOIUrl":"https://doi.org/10.3109/00365599.2011.621144","url":null,"abstract":"Objective: Dilating vesicoureteral reflux (VUR) has been linked to febrile urinary tract infection (UTI) and renal scarring. It is unclear, however, whether children with reflux should be treated surgically or medically, or just kept under close surveillance with prompt treatment of UTIs. This lack of evidence makes parental preferences a crucial factor in the choice of therapy. The Swedish Reflux Trial was set up to compare the three treatment alternatives prospectively. This paper focuses on parental experience and satisfaction after completing the trial.Material and methods: A group of 203 children aged 12-24 months with reflux grade III or IV were randomly assigned to antibiotic prophylaxis (n = 69), surveillance (n = 68) or endoscopic injection treatment (n = 66) and followed closely for 2 years. Afterwards, the families were interviewed by an investigator not involved in the care of the children about their experience of the study.Results: Parental satisfaction with the treatment given was high, with 53% scoring 5 and 35% 4 on a five-grade scale, with no difference between the three groups (p = 0.5). Recurrence of febrile UTI or new kidney scarring did not influence parental satisfaction. Even though the satisfaction was high regardless of therapy, parents of children in the prophylaxis group more often than others would have chosen another treatment if given a choice.Conclusions: As far as parental satisfaction and preferences are concerned, antibiotic prophylaxis, surveillance and injection treatment are equivalent treatment strategies in children with VUR.","PeriodicalId":21543,"journal":{"name":"Scandinavian Journal of Urology and Nephrology","volume":"46 1","pages":"26-30"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00365599.2011.621144","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30215290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 9

Is plasma symmetric dimethylarginine a suitable marker of renal function in children and adolescents? 血浆对称二甲基精氨酸是儿童和青少年肾功能的合适指标吗?

Scandinavian Journal of Urology and Nephrology Pub Date : 2012-02-01 Epub Date: 2011-10-24 DOI: 10.3109/00365599.2011.630013

Anna Wasilewska, Katarzyna Taranta-Janusz, Walentyna Zoch-Zwierz, Joanna Michaluk-Skutnik

{"title":"Is plasma symmetric dimethylarginine a suitable marker of renal function in children and adolescents?","authors":"Anna Wasilewska, Katarzyna Taranta-Janusz, Walentyna Zoch-Zwierz, Joanna Michaluk-Skutnik","doi":"10.3109/00365599.2011.630013","DOIUrl":"https://doi.org/10.3109/00365599.2011.630013","url":null,"abstract":"Objective: The purpose of this cross-sectional study was to identify whether plasma symmetric dimethylarginine (pSDMA) is a useful marker of renal function in children.Material and methods: The study group consisted of 35 patients with chronic kidney disease (CKD) stages 1-5 (median age 11.5 years), classified on the basis of estimated glomerular filtration rate (eGFR) and divided into three groups: group A, patients with CKD stages 1 and 2; group B, CKD stage 3; and group C, CKD stages 4 and 5. A control group included 42 age-matched healthy children. Commercial enzyme-linked immunosorbent assay kits were used to measure pSDMA and serum cystatin C (sCysC) concentrations.Results: The pSDMA and sCysC levels were significantly elevated in all CKD patients in comparison with healthy controls (p < 0.05). The pSDMA level in children was increased in the mild CKD (group A) (p < 0.01). There were also a significant difference in pSDMA concentration between groups A and B (p < 0.01). No differences in pSDMA levels were found between groups B and C. Receiver operating characteristics analyses showed that pSDMA was a better diagnostic tool than sCysC for identifying CKD stage among all the examined children and for detecting patients from group A (eGFR >60 ml/min/1.73 m(2)).Conclusions: Increased pSDMA and sCysC levels were found in CKD children. Further studies are required to confirm potential applications of pSDMA and CysC as useful biomarkers for the diagnosis and progression of CKD.","PeriodicalId":21543,"journal":{"name":"Scandinavian Journal of Urology and Nephrology","volume":"46 1","pages":"58-64"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00365599.2011.630013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30225048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Predictive factors for urinary retention following kidney transplantation in male patients. 男性肾移植术后尿潴留的预测因素。

Scandinavian Journal of Urology and Nephrology Pub Date : 2012-02-01 Epub Date: 2011-11-14 DOI: 10.3109/00365599.2011.633225

C Gratzke, A Pahde, M Dickmann, O Reich, M Seitz, K Jauch, C G Stief, M Siebels

{"title":"Predictive factors for urinary retention following kidney transplantation in male patients.","authors":"C Gratzke, A Pahde, M Dickmann, O Reich, M Seitz, K Jauch, C G Stief, M Siebels","doi":"10.3109/00365599.2011.633225","DOIUrl":"https://doi.org/10.3109/00365599.2011.633225","url":null,"abstract":"Objective: Urinary retention frequently occurs in patients after kidney transplantation. This study aimed to identify predictive factors for urinary retention requiring transurethral resection of the prostate (TURP) following kidney transplantation.Material and methods: Seventy male patients (median age 56 years, range 37-73 years) who underwent kidney transplantation between 1995 and 2006, and experienced urinary retention and consecutively required TURP, were studied retrospectively. Residual diuresis before transplantation, duration of dialysis, patient age, prostate size, rejection reactions, transplant loss, combined kidney and pancreas transplantation, type 1 and 2 diabetes mellitus, and carcinoma of the prostate were evaluated as predictive factors.Results: Duration of dialysis longer than 120 months (p = 0.0174), patient age over 60 years (p = 0.0045) and the absence of diabetes (n = 46, p = 0.0029) were associated with a significantly higher risk of urinary retention requiring TURP following kidney transplantation. Residual diuresis, prostate size, frequency of rejection reactions, transplant loss and detection of carcinoma, however, could not be identified as predictive factors.Conclusions: In male patients after kidney transplantation with a long history of dialysis, early TURP due to urinary retention must be anticipated. Surprisingly, the presence of type 1 or 2 diabetes seems to prevent the occurrence of retention, independently of age.","PeriodicalId":21543,"journal":{"name":"Scandinavian Journal of Urology and Nephrology","volume":"46 1","pages":"44-7"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00365599.2011.633225","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30249105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 16

A decision support model for cost-effectiveness of radical prostatectomy in localized prostate cancer. 局部前列腺癌根治性前列腺切除术成本-效果的决策支持模型。

Scandinavian Journal of Urology and Nephrology Pub Date : 2012-02-01 Epub Date: 2011-09-12 DOI: 10.3109/00365599.2011.615759

Johan Lyth, Swen-Olof Andersson, Ove Andrén, Jan-Erik Johansson, Per Carlsson, Nosrat Shahsavar

{"title":"A decision support model for cost-effectiveness of radical prostatectomy in localized prostate cancer.","authors":"Johan Lyth, Swen-Olof Andersson, Ove Andrén, Jan-Erik Johansson, Per Carlsson, Nosrat Shahsavar","doi":"10.3109/00365599.2011.615759","DOIUrl":"https://doi.org/10.3109/00365599.2011.615759","url":null,"abstract":"Objective: This study aimed to develop a probabilistic decision support model to calculate the lifetime incremental cost-effectiveness ratio (ICER) between radical prostatectomy and watchful waiting for different patient groups.Material and methods: A randomized trial (SPCG-4) provided most data for this study. Data on survival, costs and quality of life were inputs in a decision analysis, and a decision support model was developed. The model can generate cost-effectiveness information on subgroups of patients with different characteristics.Results: Age was the most important independent factor explaining cost-effectiveness. The cost-effectiveness value varied from 21,026 Swedish kronor (SEK) to 858,703 SEK for those aged 65 to 75 years, depending on Gleason scores and prostate-specific antigen (PSA) values. Information from the decision support model can support decision makers in judging whether or not radical prostatectomy (RP) should be used to treat a specific patient group.Conclusions: The cost-effectiveness ratio for RP varies with age, Gleason scores, and PSA values. Assuming a threshold value of 200,000 SEK per quality-adjusted life-year (QALY) gained, for patients aged ≤70 years the treatment was always cost-effective, except at age 70, Gleason 0-4 and PSA ≤10. Using the same threshold value at age 75, Gleason 7-9 (regardless of PSA) and Gleason 5-6 (with PSA >20) were cost-effective. Hence, RP was not perceived to be cost-effective in men aged 75 years with low Gleason and low PSA. Higher threshold values for patients with clinically localized prostate cancer could be discussed.","PeriodicalId":21543,"journal":{"name":"Scandinavian Journal of Urology and Nephrology","volume":"46 1","pages":"19-25"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00365599.2011.615759","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30132327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 8

Urinary tract cancer in patients with hereditary non-polyposis colorectal cancer. 遗传性非息肉病性结直肠癌患者的尿路癌。

Scandinavian Journal of Urology and Nephrology Pub Date : 2012-02-01 Epub Date: 2011-07-19 DOI: 10.3109/00365599.2011.599334

Peter Zachhau, Steen Walter

引用次数: 8

Long-term follow-up after radical cystectomy with emphasis on complications and reoperations: a Swedish population-based survey. 根治性膀胱切除术后的长期随访，重点是并发症和再手术:一项基于瑞典人群的调查。

Scandinavian Journal of Urology and Nephrology Pub Date : 2012-02-01 Epub Date: 2011-08-19 DOI: 10.3109/00365599.2011.609835

Fredrik Liedberg, Erik Holmberg, Sten Holmäng, Börje Ljungberg, Per-Uno Malmström, Wiking Månsson, Leyla Nunez, Catrin Wessman, Hans Wijkström, Staffan Jahnson

{"title":"Long-term follow-up after radical cystectomy with emphasis on complications and reoperations: a Swedish population-based survey.","authors":"Fredrik Liedberg, Erik Holmberg, Sten Holmäng, Börje Ljungberg, Per-Uno Malmström, Wiking Månsson, Leyla Nunez, Catrin Wessman, Hans Wijkström, Staffan Jahnson","doi":"10.3109/00365599.2011.609835","DOIUrl":"https://doi.org/10.3109/00365599.2011.609835","url":null,"abstract":"Abstract Objective. To evaluate outcome after radical cystectomy for primary bladder cancer in a large population-based material. Material and methods. Between 1997 and 2002 all patients treated with radical cystectomy within 3 months after diagnosis of primary bladder cancer without distant metastasis were retrieved through the Swedish Bladder Cancer Registry. A follow-up questionnaire was distributed to all units where the primary registration of patients was performed. Follow-up data on recurrence date were retrieved from the patient charts and causes of death were obtained from the Swedish Cause of Death Registry until 2003. Results. During the study period radical cystectomy was performed in 39 units in Sweden, of which only five units were considered high-volume hospitals performing 10 or more procedures annually. Mean blood loss was 2300 ml (median 2000 ml) and the 90-day mortality rate was 5.7%. Blood loss was higher in high-volume units than in hospitals with lower hospital volumes, but the 90-day mortality rates were similar. During a median follow-up of 3.5 years, 24% of the patients were submitted to a reoperation. Reoperation rates were significantly higher in patients who received a continent urinary diversion (29%) compared with an ileal conduit (22%, p < 0.015). Conclusions. Radical cystectomy was associated with a reoperation rate of 24% in Sweden during the study period. The reoperation rates were higher in patients receiving a continent cutaneous diversion or bladder substitution. Blood loss was higher in high-volume units; otherwise, surgical volume did not affect mortality rates, cancer-specific survival or reoperation rates.","PeriodicalId":21543,"journal":{"name":"Scandinavian Journal of Urology and Nephrology","volume":"46 1","pages":"14-8"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00365599.2011.609835","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30087951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 21

Fatal case of ectopic enterobiasis: Enterobius vermicularis in the kidneys. 异位肠虫病的致命病例:肾脏中的蛭状肠虫。

Scandinavian Journal of Urology and Nephrology Pub Date : 2012-02-01 Epub Date: 2011-08-31 DOI: 10.3109/00365599.2011.609834

Mindaugas Serpytis, Dmitrij Seinin

引用次数: 28

Paraurethral cyst in two female newborns: which therapy option? 2例女性新生儿尿道旁囊肿:哪种治疗方案?

Scandinavian Journal of Urology and Nephrology Pub Date : 2012-02-01 Epub Date: 2011-07-20 DOI: 10.3109/00365599.2011.599337

Yavuz Yilmaz, Istemi Han Celik, Evrim Alyamac Dizdar, Gamze Demirel, Sadik Yurttutan, Omer Erdeve, Serife Suna Oguz, Ugur Dilmen

{"title":"Paraurethral cyst in two female newborns: which therapy option?","authors":"Yavuz Yilmaz, Istemi Han Celik, Evrim Alyamac Dizdar, Gamze Demirel, Sadik Yurttutan, Omer Erdeve, Serife Suna Oguz, Ugur Dilmen","doi":"10.3109/00365599.2011.599337","DOIUrl":"https://doi.org/10.3109/00365599.2011.599337","url":null,"abstract":"Paraurethral cysts are rare in females, especially in the neonatal period. The aetiology of congenital paraurethral cysts is obstruction of Skene's ducts from para/periurethral glands. Paraurethral cysts may be totally asymptomatic, non-tender, soft, cystic, ovoid masses about 6-10 mm in size and yellowish in colour. These lesions may be discovered on either side of the urethral meatus during routine examination and most of these resolve spontaneously. This study reports two female newborns with paraurethral cysts treated with needle aspiration because of difficulty in excretion of urine on the first day of life. The second case needed another course of needle aspiration 1 month later. There is no consensus on the treatment because of the benign nature of the paraurethral cysts and the probability of spontaneous regression. Surgical alternatives include excision, marsupialization and needle aspiration. If a surgical approach is needed, e.g. because of difficulty in urination, needle aspiration should be used as the initial surgical intervention.","PeriodicalId":21543,"journal":{"name":"Scandinavian Journal of Urology and Nephrology","volume":"46 1","pages":"78-80"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00365599.2011.599337","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30016499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 10

Incidence of nephrogenic systemic fibrosis at a large university hospital in Sweden. 瑞典一家大型大学医院肾源性全身性纤维化的发生率。

Scandinavian Journal of Urology and Nephrology Pub Date : 2012-02-01 Epub Date: 2011-10-19 DOI: 10.3109/00365599.2011.621142

Alaa Alhadad, Gunnar Sterner, Åke Svensson, Hussein Alhadad, Peter Leander

{"title":"Incidence of nephrogenic systemic fibrosis at a large university hospital in Sweden.","authors":"Alaa Alhadad, Gunnar Sterner, Åke Svensson, Hussein Alhadad, Peter Leander","doi":"10.3109/00365599.2011.621142","DOIUrl":"https://doi.org/10.3109/00365599.2011.621142","url":null,"abstract":"Objective: Nephrogenic systemic fibrosis (NSF) is a rare condition that may follow administration of gadolinium-based contrast media (Gd-CM) in patients with renal insufficiency. This study was initiated to determine the incidence of NSF at Skåne University Hospital, Malmö, in Sweden.Material and methods: During the period January 2001 to December 2008 10 650 patients underwent magnetic resonance imaging (MRI) examinations. The re-expressed four-variable Modification of Diet in Renal Disease (MDRD) equation was used to calculate the estimated glomerular filtration rate (eGFR). The 272 patients with an eGFR <30 ml/min/1.73 m2 who were given Gd-CM were selected for final analysis. A diagnosis of NSF or other dermatological diagnoses in the 272 patients was searched for in the database of the Departments of Dermatology and Pathology.Results: The 272 patients, of whom 26 patients were on dialysis, had undergone 406 MRI examinations with Gd-CM. Mean follow-up time was 3.9 (±2.7 SD) years. Assuming a mean body weight of 70 kg, the overall median dose of the 406 examinations with Gd-CM was 0.14 mmol/kg body weight (0.06, 0.34; 2.5-97.5 percentiles). In this retrospective study of patients with eGFR <30 ml/min/1.73 m(2), none developed NSF (the upper 95% confidence limit for zero cases of NSF in the 272 patients was 2.3%).Conclusion: Although it is premature to claim that Gd-CM using the regimen employed in this institution is safe to use in all patients with eGFR <30 ml/min/1.73 m(2), the results.indicate that development of NSF is extremely uncommon.","PeriodicalId":21543,"journal":{"name":"Scandinavian Journal of Urology and Nephrology","volume":"46 1","pages":"48-53"},"PeriodicalIF":0.0,"publicationDate":"2012-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/00365599.2011.621142","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"30217152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 12