遗传性非息肉病性结直肠癌患者的尿路癌。

Peter Zachhau, Steen Walter
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引用次数: 8

摘要

目的:遗传性非息肉性结直肠癌(HNPCC),或Lynch综合征,是一种遗传性结直肠癌,在身体其他部位发生癌症的风险增加。材料和方法:自2001年11月以来,在欧登塞大学医院泌尿外科对20例HNPCC患者进行了泌尿道肿瘤筛查。在筛查期间回顾了所有患者的临床记录和病理结果。结果:在筛查过程中发现2例无泌尿系统症状的患者有输尿管癌。结论:HNPCC患者发生尿路癌的危险性增高,应进行尿路筛查。探讨对HNPCC患者进行尿路癌筛查的合理策略,并开展进一步的筛查研究也很重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Urinary tract cancer in patients with hereditary non-polyposis colorectal cancer.

Objective: Hereditary non-polyposis colorectal cancer (HNPCC), or Lynch syndrome, is characterized as a hereditary colorectal cancer with an increased risk of cancer elsewhere in the body.

Material and methods: In the Department of Urology at Odense University Hospital, screening for cancer in the urinary tract has been carried out on 20 patients with HNPCC since November 2001. Clinical records and pathology results were reviewed for all patients during the screening period.

Results: During screening two patients without urological symptoms were found to have cancer in the ureter.

Conclusions: HNPCC patients with increased risk of urinary tract cancer should be referred for screening of the urinary tract. It is also important to discuss a rational strategy towards the screening of HNPCC patients for urinary tract cancer, and to initiate further investigation into this screening.

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来源期刊
Scandinavian Journal of Urology and Nephrology
Scandinavian Journal of Urology and Nephrology 医学-泌尿学与肾脏学
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