Royal Society Open Science最新文献_第2页

Ontogeny of settlement behaviours in response to Grammatophora marina diatom biofilms in the marine polychaete, Platynereis dumerilii. 海洋多毛类对滨海藻藻生物膜的沉降行为的个体发生。

IF 3 3区综合性期刊

Royal Society Open Science Pub Date : 2026-10-07 DOI: 10.1098/rsos.261521

Callum Teeling, Susanne Vogeler, Robert P Ellis, Elizabeth A Williams

{"title":"Ontogeny of settlement behaviours in response to Grammatophora marina diatom biofilms in the marine polychaete, Platynereis dumerilii.","authors":"Callum Teeling, Susanne Vogeler, Robert P Ellis, Elizabeth A Williams","doi":"10.1098/rsos.261521","DOIUrl":"10.1098/rsos.261521","url":null,"abstract":"Settlement, the transition of a swimming planktonic larva to a benthic juvenile, is a key process during the development of many marine invertebrates. Microbial biofilms act as positive cues for larval settlement across species, yet the behavioural processes preceding settlement are poorly understood. Here, we investigated age-dependent changes in settlement behaviour in marine polychaete Platynereis dumerilii larvae in response to Grammatophora marina diatom biofilms. Settlement behaviours (crawling, crawling speed and track straightness) were quantified from recordings of larvae ranging from the mid-trochophore to late-nectochaete in the presence or absence of diatom biofilms, using spot-tracking software. As larvae developed, the proportion of individuals crawling over the biofilm increased. Older larvae colonized biofilms more rapidly and showed greater discrimination between G. marina biofilms and controls. Older larvae straighten their movements compared with individuals swimming in the presence of biofilms, or behaviour witnessed in the absence of biofilms. The prevalence of these behaviours may reflect changes in the prioritization of sensory inputs from physical and chemical cues as larvae develop. Our findings suggest that settlement behaviours are developmentally programmed in P. dumerilii. Understanding settlement behaviours in P. dumerilii expands on this species' behavioural repertoire and sheds light on the evolutionary relationship between marine larvae and microalgal biofilms.","PeriodicalId":21525,"journal":{"name":"Royal Society Open Science","volume":"13 10","pages":"261521"},"PeriodicalIF":3.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149114597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

On the potential for crop yield increases to spare land: the role of rebound effects. 论潜在粮食增产对闲置土地的作用：反弹效应。

IF 3 3区综合性期刊

Royal Society Open Science Pub Date : 2026-10-07 DOI: 10.1098/rsos.260431

Nelson B Villoria

{"title":"On the potential for crop yield increases to spare land: the role of rebound effects.","authors":"Nelson B Villoria","doi":"10.1098/rsos.260431","DOIUrl":"10.1098/rsos.260431","url":null,"abstract":"This essay discusses the economic mechanisms determining when yield growth spares land and when it drives expansion. The source of growth matters: technical change raises output with a fixed set of inputs, lowering production costs, whereas intensification requires more inputs and, unless those inputs are themselves more productive, raises costs. Because lower costs translate into lower prices, the outcome turns on how consumption responds. Where demand is inelastic, so that consumption changes less than proportionally to price, productivity gains lower farm profits and spare land, although rebound effects mean sparing is rarely complete. Where demand is elastic, gains raise profitability and cultivated area expands if land is available (backfire or Jevons effect). Farmers in agricultural frontiers supplying large domestic and international markets face elastic demand, making such regions prone to backfire. Globally, however, demand for agricultural output has been historically inelastic. This fact, combined with vigorous growth in global agricultural productivity, has resulted in net global land sparing. A slowdown in total factor productivity growth over the last decade and a half threatens these gains. Sustaining this outcome requires renewed investment in agricultural research and development, and policies that constrain frontier expansion.","PeriodicalId":21525,"journal":{"name":"Royal Society Open Science","volume":"13 10","pages":"260431"},"PeriodicalIF":3.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641888/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149114563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A dental dilemma: bear teeth reveal a spatial gradient in age of primiparity, but temporal trends muddled when bears grew fast. 牙齿的困境：熊的牙齿揭示了初产年龄的空间梯度，但当熊长得快时，时间趋势就混乱了。

IF 3 3区综合性期刊

Royal Society Open Science Pub Date : 2026-10-07 DOI: 10.1098/rsos.252109

Andrew N Tri, David L Garshelis, Pamela L Coy, Carolin A Humpal, Karen V Noyce

{"title":"A dental dilemma: bear teeth reveal a spatial gradient in age of primiparity, but temporal trends muddled when bears grew fast.","authors":"Andrew N Tri, David L Garshelis, Pamela L Coy, Carolin A Humpal, Karen V Noyce","doi":"10.1098/rsos.252109","DOIUrl":"10.1098/rsos.252109","url":null,"abstract":"Age of primiparity (AOP) in American black bears (Ursus americanus) is driven by nutrition. We estimated AOP from patterns of cementum annuli in female bear teeth (more than 16 000), which were collected from hunters in Minnesota, USA, over five decades. AOP was delayed in northern Minnesota and hastened southward, matching the increasing food availability. In the core of the bear range, AOP remained stable at 5.3 years, whereas along the range edge, AOP increased from 4.5 years in the 1970s to 5.0 years in the 2010s. We posed five hypotheses to explain this enigmatic trend; (i) change in tooth readers, (ii) declining foods, (iii) increased density-dependent effects, (iv) hunters killing fast-growing juveniles, and (v) limits to the technique used. We rejected the first four hypotheses by comparing tooth readers and exploiting data on bear foods, age-specific bear masses, population trends and observed AOPs of radio-collared bears in each region. We concluded that food increased along the range edge, spurring faster-growing bears, which had harder to interpret cementum annuli. We previously developed and tested this technique on slower-growing bears. Teeth from harvested bears are a valuable source of reproductive information, but the technique may fail when employed beyond the tested limits of the bears' nutrition.","PeriodicalId":21525,"journal":{"name":"Royal Society Open Science","volume":"13 10","pages":"252109"},"PeriodicalIF":3.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641896/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149114574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Computational identification of potential inhibitors for chikungunya virus nsP2pro. 基孔肯雅病毒nsP2pro潜在抑制剂的计算鉴定。

IF 3 3区综合性期刊

Royal Society Open Science Pub Date : 2026-10-07 DOI: 10.1098/rsos.252347

Hoang Anh Nguyen, Son Tung Ngo

{"title":"Computational identification of potential inhibitors for chikungunya virus nsP2pro.","authors":"Hoang Anh Nguyen, Son Tung Ngo","doi":"10.1098/rsos.252347","DOIUrl":"10.1098/rsos.252347","url":null,"abstract":"Chikungunya virus remains a crucial global health issue with no approved therapy available. In particular, the viral replication is associated with the non-structural protein 2 protease (nsP2pro). In this study, possible inhibitors for nsP2pro from the National Cancer Institute (NCI) database were screened via computational approaches. Molecular docking simulations were initially predicted top potential ligands. MD simulations were then performed to refine the ligand binding pose. During the equilibrium intervals, the ligands formed rigid contacts with the residues Asn476, Ala511, Tyr512, Tyr544 and Trp549 of nsP2pro. Moreover, five compounds probably prevent the biological activity of nsP2pro by increasing the distance of Cys478-Sγ-Nε-His548 and Ser482-Oγ-Nε-His548 pairs. Furthermore, perturbation simulations finally confirmed that NSC 319990, NSC 80731, NSC 80735, NSC 67436 and NSC 37553 compounds exhibited significantly stronger binding affinity, ranging from -9.70 ± 0.61 to -11.71 ± 1.25 kcal mol-1, than that of the available inhibitor RA-0002034, ΔG FEP = - 6.45 ± 0.32 kcal mol-1. Besides, the strong correlation between ΔG FEP and Cys478-Sγ-Nε-His548 pair suggests that a stronger binding ligand better inhibits the biological activity of nsP2pro. Overall, these findings suggest that five NCI compounds are highly promising candidates for further experimental validation as novel nsP2pro inhibitors.","PeriodicalId":21525,"journal":{"name":"Royal Society Open Science","volume":"13 10","pages":"252347"},"PeriodicalIF":3.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641887/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149114602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Serological and transcriptomic response of African fruit bats to immune challenge with recombinant vaccines expressing Ebola or Nipah virus antigens. 非洲果蝠对表达埃博拉或尼帕病毒抗原的重组疫苗免疫攻击的血清学和转录组学反应

IF 3 3区综合性期刊

Royal Society Open Science Pub Date : 2026-10-07 DOI: 10.1098/rsos.252189

Elinor Jax, Romain Garnier, Georgia Tsagkogeorga, Hubert Buczkowski, Louise Gibson, Pius Benia, Richard Suu-Ire, Vera M Warmuth, Sylvester Languon, Osbourne Quaye, Lianying Yan, Christopher C Broder, Stephen J Rossiter, Edward Wright, Sarah C Gilbert, Teresa Lambe, James L N Wood, Andrew A Cunningham, Olivier Restif

{"title":"Serological and transcriptomic response of African fruit bats to immune challenge with recombinant vaccines expressing Ebola or Nipah virus antigens.","authors":"Elinor Jax, Romain Garnier, Georgia Tsagkogeorga, Hubert Buczkowski, Louise Gibson, Pius Benia, Richard Suu-Ire, Vera M Warmuth, Sylvester Languon, Osbourne Quaye, Lianying Yan, Christopher C Broder, Stephen J Rossiter, Edward Wright, Sarah C Gilbert, Teresa Lambe, James L N Wood, Andrew A Cunningham, Olivier Restif","doi":"10.1098/rsos.252189","DOIUrl":"10.1098/rsos.252189","url":null,"abstract":"Bats are hosts to diverse zoonotic viruses which can cause high case fatality rates in humans. Since detecting viruses in bats is difficult, antibodies are often used for surveillance, though their significance remains unclear in the absence of in vivo immunological studies. To address this knowledge gap, we measured antibody production and gene expression in bats following injection with vaccines encoding either a Nipah virus G glycoprotein or an Ebola virus GP glycoprotein. We selected two African bat species with overlapping ranges, Eidolon helvum (confirmed reservoir of henipaviruses) and Epomophorus gambianus (putative reservoir of filoviruses). Using a Luminex-based multiplex microsphere immunoassay and a pseudotype virus neutralization assay, we observed an increase in antibodies against the Nipah glycoprotein in most bats that received the Nipah vaccine. In contrast, we could only detect anti-Ebola glycoprotein antibodies in one bat species, Ep. gambianus, in response to the Ebola vaccine. Transcriptomic analysis in Ei. helvum revealed that genes involved in ISGylation and T-cell differentiation pathways were differentially expressed in response to the Ebola, but not the Nipah, vaccine. These results demonstrate species-specific differences in responses to antigen exposure, offering insights into bat adaptive immune systems and providing calibration for serological data from wild bats.","PeriodicalId":21525,"journal":{"name":"Royal Society Open Science","volume":"13 10","pages":"252189"},"PeriodicalIF":3.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149128464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A constructional theory of sets, parts and relations. 集合、部分和关系的构造理论。

IF 3 3区综合性期刊

Royal Society Open Science Pub Date : 2026-10-07 DOI: 10.1098/rsos.251390

Salvatore Florio, Øystein Linnebo

引用次数: 0

Trophic position structures physiological trade-offs between metabolic and detoxification pathways in sympatric passerines. 营养位置结构的生理权衡之间的代谢和解毒途径在同域雀形目。

IF 3 3区综合性期刊

Royal Society Open Science Pub Date : 2026-10-07 DOI: 10.1098/rsos.261499

Pablo Sabat, Antonia Beltran-Hayet, Francisco Del Basto, Benjamin Corvalán, Natalia Ramirez-Otarola, Felipe Alvarez-Vergara, Diego Landaeta, Roberto Nespolo, Juan C Sanchez-Hernandez, Karin Maldonado, Seth D Newsome

{"title":"Trophic position structures physiological trade-offs between metabolic and detoxification pathways in sympatric passerines.","authors":"Pablo Sabat, Antonia Beltran-Hayet, Francisco Del Basto, Benjamin Corvalán, Natalia Ramirez-Otarola, Felipe Alvarez-Vergara, Diego Landaeta, Roberto Nespolo, Juan C Sanchez-Hernandez, Karin Maldonado, Seth D Newsome","doi":"10.1098/rsos.261499","DOIUrl":"10.1098/rsos.261499","url":null,"abstract":"Resource use links ecological context to organismal performance, yet whether dietary breadth or trophic position is more closely associated with physiological state in wild birds remains unclear. We used a natural trophic gradient in a sympatric passerine assemblage to test whether trophic position and isotopic niche breadth are associated with integrated physiological phenotypes. We studied three co-occurring passerine species in central Chile spanning a trophic spectrum (granivorous, omnivorous, insectivorous). Using blood <math><mi>δ</mi></math> 13C and <math><mi>δ</mi></math> 15N, we quantified isotopic niche width and estimated trophic position, then compared these metrics with physiological variables measured in free-living birds (n = 60), including differential leukocyte counts, antioxidant capacity, and enzymatic markers of oxidative metabolism, glutathione-related physiology, and plasma esterase activity. Isotopic niche width differed among species but was weakly associated with physiological variation. By contrast, estimated trophic position showed stronger species-level correspondence with multivariate physiological organization. Metabolic and enzyme-based variables contributed most to interspecific physiological differentiation, whereas baseline non-enzymatic antioxidant buffering was conserved. Overall, estimated trophic position showed a stronger correspondence with coordinated physiological variation than isotopic niche breadth. These findings highlight species-level physiological differences associated with trophic position and provide a basis for broader comparative analyses of ecological and evolutionary influences on avian physiology.","PeriodicalId":21525,"journal":{"name":"Royal Society Open Science","volume":"13 10","pages":"261499"},"PeriodicalIF":3.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149114522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wind conditions shape co-migration fidelity in trans-Saharan birds at a Mediterranean stopover site. 在地中海中转站，风条件影响了跨撒哈拉鸟类的共同迁徙保真度。

IF 3 3区综合性期刊

Royal Society Open Science Pub Date : 2026-10-07 DOI: 10.1098/rsos.260539

Erica Calabretta, Bruno Bellisario, Claudio Carere, Ivan Maggini, Massimiliano Cardinale, Elizabeth Yohannes, Leonida Fusani

{"title":"Wind conditions shape co-migration fidelity in trans-Saharan birds at a Mediterranean stopover site.","authors":"Erica Calabretta, Bruno Bellisario, Claudio Carere, Ivan Maggini, Massimiliano Cardinale, Elizabeth Yohannes, Leonida Fusani","doi":"10.1098/rsos.260539","DOIUrl":"10.1098/rsos.260539","url":null,"abstract":"Weather is a key driver of bird migration, particularly near ecological barriers, where migratory species often converge before crossing. While its effects on individual timing are well documented, how weather reshapes the temporal assemblage of migratory bird communities remains unexplored. Using 18 years of standardised ringing data from 24 trans-Saharan species during pre-breeding migration, this study investigated whether weather conditions along the Mediterranean Sea influence annual network modularity, that is, the yearly interspecific clusters of co-occurrence at a stopover site, and measured the 'co-migration fidelity', defined as the tendency of species to co-occur in the same cluster over the years. Specifically, we examined the 'modularity' associations with tailwinds, temperature, and the North Atlantic Oscillation (NAO) index. Modularity increased significantly over time, revealing non-random species clusters whose arrival timing aligns under unfavourable winds. This suggests that less supportive winds may lead distinct species to migrate within the same narrow temporal window of favourable conditions, heightening co-migration fidelity. Conversely, modularity decreased sharply in years with stronger tailwinds, while temperature and NAO showed negligible effects. These findings provide novel evidence that shared environmental constraints during the sea crossing can shape the formation of migratory communities by prompting species' temporal convergence at a stopover.","PeriodicalId":21525,"journal":{"name":"Royal Society Open Science","volume":"13 10","pages":"260539"},"PeriodicalIF":3.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149114528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Built for bulk: posture, microanatomy and soft tissue shaped gigantism in Sauropoda. 为体积而建：蜥脚类动物的姿势、显微解剖学和软组织形状的巨人症。

IF 3 3区综合性期刊

Royal Society Open Science Pub Date : 2026-10-07 DOI: 10.1098/rsos.261186

Julian C G Silva Junior, Gabriel Souza Ferreira, Agustin G Martinelli, Thiago da S Marinho, Felipe C Montefeltro

{"title":"Built for bulk: posture, microanatomy and soft tissue shaped gigantism in Sauropoda.","authors":"Julian C G Silva Junior, Gabriel Souza Ferreira, Agustin G Martinelli, Thiago da S Marinho, Felipe C Montefeltro","doi":"10.1098/rsos.261186","DOIUrl":"10.1098/rsos.261186","url":null,"abstract":"Sauropodomorph dinosaurs show how appendicular skeletal architecture accommodated extreme increases in body mass. Although sauropod gigantism has been linked to columnar limbs, wide-gauge posture, thick articular cartilage and tubular long-bone organization, the biomechanical interaction among these components is poorly understood. Here, we examine how femo ral shape, internal bone architecture and articular soft tissues influenced mechanical scaling across Sauropodomorpha. We generated three-dimensional femoral models spanning early sauropodomorphs, narrow-gauge diplodocoids, intermediate-gauge titanosauriforms, wide-gauge titanosaurs and an African elephant control. Finite element analyses compared theoretical solid models with taxon-specific native configurations, incorporating medullary cavities and articular cartilage caps. Mechanical performance was assessed using 95th-percentile von Mises stress, strain energy density and structural stiffness. Femoral performance did not scale uniformly with body mass. The two sampled narrow-gauge taxa, Diplodocus and Amargasaurus, defined steeper scaling trajectories for stress and strain energy density, whereas wide-gauge titanosaurs generally displayed flatter trajectories, comparatively lower stress and strain energy density, and elevated stiffness in several large-bodied forms. Targeted sensitivity analyses further showed that the mechanical effects of medullary architecture and cartilage depended on their interaction with taxon-specific femoral geometry. These findings suggest that sauropod gigantism was sustained by lineage-specific combinations of femoral geometry, internal architecture and articular soft tissues.","PeriodicalId":21525,"journal":{"name":"Royal Society Open Science","volume":"13 10","pages":"261186"},"PeriodicalIF":3.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641891/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149114535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ant brain metabolomics reveals contrasting purine and amine dynamics in a reversible trematode-induced host manipulation. 蚂蚁脑代谢组学揭示了在可逆吸虫诱导的宿主操作中嘌呤和胺的动态对比。

IF 3 3区综合性期刊

Royal Society Open Science Pub Date : 2026-10-07 DOI: 10.1098/rsos.261298

Chen-Hua Li, Cameron Goater, James Wasmuth

{"title":"Ant brain metabolomics reveals contrasting purine and amine dynamics in a reversible trematode-induced host manipulation.","authors":"Chen-Hua Li, Cameron Goater, James Wasmuth","doi":"10.1098/rsos.261298","DOIUrl":"10.1098/rsos.261298","url":null,"abstract":"The neurochemical mechanisms underlying parasite-induced host manipulations remain poorly understood. Formicid ants infected with lancet fluke, Dicrocoelium dendriticum, attach to vegetation with their mandibles during cool conditions, facilitating ingestion by grazing mammals-the obligate definitive host. Following several hours of attachment, ants detach, return to their nests, then repeat the attach/detach sequence on subsequent days. To investigate the molecular basis of this reversible manipulation, we used targeted and untargeted metabolomics to compare the brain chemistry of infected and uninfected field-collected ants during four sequential phases of manipulation. Targeted analysis of biogenic amines showed that tyramine and serotonin concentrations were 16% and 22% lower, respectively, in infected versus uninfected ants, but only during the detachment phase. Untargeted metabolomics revealed that the purine adenosine was 190% higher in infected ants during attachment. This result implicates the adenosine pathway, a key regulator of insect sleep/wake cycles, feeding inhibition and immune responsiveness, in the induction of the immobile, biting phase. Taurine levels were also reduced in the infected ants, potentially suppressing eusocial behaviours such as nest leaving. These results suggest that D. dendriticum uses distinct neurochemical mechanisms to orchestrate contrasting phases of manipulation: adenosine-mediated induction of attachment and biogenic amine-mediated regulation of detachment.","PeriodicalId":21525,"journal":{"name":"Royal Society Open Science","volume":"13 10","pages":"261298"},"PeriodicalIF":3.0,"publicationDate":"2026-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13641915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149114564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0