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Revista Espanola De Enfermedades Digestivas最新文献

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Gastric heterotopia in the rectum: a rare entity with potential pitfalls. 胃异位在直肠:一个罕见的实体与潜在的陷阱。
IF 2.7 4区 医学
Revista Espanola De Enfermedades Digestivas Pub Date : 2025-02-01 DOI: 10.17235/reed.2023.9693/2023
André Gonçalves, Diogo Simas, Sandra Barbeiro, Helena Vasconcelos
{"title":"Gastric heterotopia in the rectum: a rare entity with potential pitfalls.","authors":"André Gonçalves, Diogo Simas, Sandra Barbeiro, Helena Vasconcelos","doi":"10.17235/reed.2023.9693/2023","DOIUrl":"10.17235/reed.2023.9693/2023","url":null,"abstract":"<p><p>Gastric heterotopia (GHT) is a medical condition where the gastric mucosa is found at a non-phyysiological part of the body. GHT can present itself anywhere in the gastrointestinal tract from the mouth to the anorectal area, as well as in the hepatobiliary system. However, it is relatively rare to find GHT in the rectum, with only around 50 documented cases reported in medical literature. We present the case of a 51-year-old man who underwent average-risk screening colonoscopy. He had no clinically significant comorbidities and was otherwise asymptomatic, with no family history. Notable findings included a pseudopolypoid lesion in the distal rectum, adjacent to the dentate line, measuring approximately 15 mm with regular-appearing mucosa under narrow-band-imaging. Biopsy specimens showed histological characteristics of oxyntic-type gastric mucosa without inflammation or dysplasia. GHT has the potential to progress to malignancy, although the rate of malignancy is currently unknown. Awareness of this entity is important given its frequency and potential for misdiagnosis.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"102-103"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9501415","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Variability in the management of GLP-1 agonists and endoscopic procedures: an opportunity for standardization. GLP-1激动剂管理和内窥镜操作的可变性：标准化的机会。
IF 2.7 4区 医学
Revista Espanola De Enfermedades Digestivas Pub Date : 2025-02-01 DOI: 10.17235/reed.2025.11011/2024
Javier Crespo, María Jesús López-Arias, Paula Iruzubieta
{"title":"Variability in the management of GLP-1 agonists and endoscopic procedures: an opportunity for standardization.","authors":"Javier Crespo, María Jesús López-Arias, Paula Iruzubieta","doi":"10.17235/reed.2025.11011/2024","DOIUrl":"10.17235/reed.2025.11011/2024","url":null,"abstract":"<p><p>Glucagon-like peptide-1 receptor agonists (GLP-1RAs), also known as incretin mimetics, have significantly revolutionized the treatment of type 2 diabetes mellitus (T2DM) and obesity worldwide, far exceeding initial expectations regarding their global prescription. This class of medications has demonstrated weight losses of up to 20 % of baseline body weight. Beyond their proven benefits in T2DM and obesity, GLP-1RAs, as well as dual and triple agonists (GLP-1/GIP/glucagon), are being investigated for their effects on conditions such as metabolic-associated steatotic liver disease, various cardiovascular disorders, neurocognitive impairments, and certain addictions. These emerging effects appear to be linked not only to their metabolic action but also to their ability to modulate the chronic inflammatory state underlying these pathologies.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":"117 ","pages":"65-67"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142984767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endoscopic treatment of Barrett´s esophagus. 巴雷特食管的内窥镜治疗。
IF 2.7 4区 医学
Revista Espanola De Enfermedades Digestivas Pub Date : 2025-02-01 DOI: 10.17235/reed.2024.10201/2023
Modesto Varas Lorenzo, Ramón Abad Belando
{"title":"Endoscopic treatment of Barrett´s esophagus.","authors":"Modesto Varas Lorenzo, Ramón Abad Belando","doi":"10.17235/reed.2024.10201/2023","DOIUrl":"10.17235/reed.2024.10201/2023","url":null,"abstract":"<p><p>A pilot, multicenter and randomised study on the treatment of Barrett´s esophagus with electro conventional scalpel versus argon plasma coagulation in 36 patients consecutives. The disappearance of gastric mucosa was achieved in 83% of cases. Not serious adverse effects.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"122-123"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139521751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intestinal intussusception in adult as an uncommon cause of mechanical obstruction. 成人肠套叠是机械性梗阻的罕见病因。
IF 2.7 4区 医学
Revista Espanola De Enfermedades Digestivas Pub Date : 2025-02-01 DOI: 10.17235/reed.2023.9698/2023
Rodolfo Manuel Batista Castillo, Raquel Martínez Alarcón, Angelina Montserrat Martí, Juan José Pamies Tomas
{"title":"Intestinal intussusception in adult as an uncommon cause of mechanical obstruction.","authors":"Rodolfo Manuel Batista Castillo, Raquel Martínez Alarcón, Angelina Montserrat Martí, Juan José Pamies Tomas","doi":"10.17235/reed.2023.9698/2023","DOIUrl":"10.17235/reed.2023.9698/2023","url":null,"abstract":"<p><p>A 61-year-old woman admitted for epigastric abdominal pain, three months of evolution, worsens after ingestion, associating abdominal distension and constipation. Physical examination: abdominal pain and distension in the mesogastric zone. Blood tests: slight increase in C-reactive protein; abdominal X-ray: the small bowel dilatation; computed tomography scan: small bowel obstruction due to intussusception. An exploratory laparotomy was performed, confirming a mechanical intestinal occlusion secondary to 5 centimeters jejunal intussusception (image 3); It was execute an intestinal resection with adequate margins and an anisoperistaltic mechanical side-to-side anastomosis. Correct postoperative evolution; hospital discharge on the sixth day. Pathology report: polypoid intussusception, 4.3x3.3 centimeters, superficial ulceration, edema, chronic inflammation; resection margins without alterations.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"104-105"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9487057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mesalamine induced hepatotoxicity. Is mesalamine safe? 美沙拉明引起的肝毒性。美沙拉明安全吗？
IF 2.7 4区 医学
Revista Espanola De Enfermedades Digestivas Pub Date : 2025-02-01 DOI: 10.17235/reed.2024.10131/2023
Javier Pérez-Valenzuela, Lorena Castro Solari, Rodrigo Quera, Luis Contreras
{"title":"Mesalamine induced hepatotoxicity. Is mesalamine safe?","authors":"Javier Pérez-Valenzuela, Lorena Castro Solari, Rodrigo Quera, Luis Contreras","doi":"10.17235/reed.2024.10131/2023","DOIUrl":"10.17235/reed.2024.10131/2023","url":null,"abstract":"<p><p>Mesalamine is a medication used widely in the treatment of patients with inflammatory bowel disease. Although mesalamine is considered safe, hepatotoxicity has been reported with an incidence of 0-4%. We present the clinical picture of a patient with hepatotoxicity due to mesalamine. A 79-year-old woman in the context of chronic diarrhea, a left-sided ulcerative colitis diagnosis was made, and treatment was initiated with oral mesalamine 4 g per day, and mesalamine suppositories. Before starting treatment, she had normal liver test results. After three months, she presented with headache, fatigue, and intermittent low fever. Her laboratory tests showed a liver profile with a cholestatic pattern, and elevation of inflammatory parameters. Mesalamine was suspended, and an extensive study was performed. Cholangioresonance reported intra and extrahepatic bile duct dilation without obstruction, and thickening of the intrahepatic bile duct. She progressed with worsening of the liver profile without signs of liver failure. A liver biopsy was performed, which showed chronic non-suppurative cholangitis with granulomas and focal concentric fibrosis related to medium-caliber bile ducts, and IgG4 stain was negative.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"108-110"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139417976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radiotherapy-induced fibrosarcoma of the esophagus. 放疗引起的食道纤维肉瘤。
IF 2.7 4区 医学
Revista Espanola De Enfermedades Digestivas Pub Date : 2025-02-01 DOI: 10.17235/reed.2023.9708/2023
Junkuo Li, Anxiang Liu, Haijun Yang, Fuyou Zhou
{"title":"Radiotherapy-induced fibrosarcoma of the esophagus.","authors":"Junkuo Li, Anxiang Liu, Haijun Yang, Fuyou Zhou","doi":"10.17235/reed.2023.9708/2023","DOIUrl":"10.17235/reed.2023.9708/2023","url":null,"abstract":"<p><p>A patient presented with a 5-year history of slowly progressive dysphagia. He had moderately differentiated squamous cell carcinoma in the middle thoracic esophagus and underwent partial esophagogastrostomy 16 years prior. The patient with postoperative anastomotic stenoses was treated with radiotherapy at a total dose of 60 Gy after esophagectomy. Endoscopic submucosal dissection (ESD) was used to treat the recurrent tumor.Clinical specimens were obtained from the ESD and the tumor was pathologically confirmed to be fibrosarcoma.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"106-107"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9480664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intestinal metastases of colorectal cancer. 大肠癌肠道转移。
IF 2.7 4区 医学
Revista Espanola De Enfermedades Digestivas Pub Date : 2025-02-01 DOI: 10.17235/reed.2024.10089/2023
Natalia Zuberoa Rosado Dawid, Raquel Díaz Martínez, Asunción Ramos Meca
{"title":"Intestinal metastases of colorectal cancer.","authors":"Natalia Zuberoa Rosado Dawid, Raquel Díaz Martínez, Asunción Ramos Meca","doi":"10.17235/reed.2024.10089/2023","DOIUrl":"10.17235/reed.2024.10089/2023","url":null,"abstract":"<p><p>We present the case of an 82-year-old woman with a history of well-differentiated adenocarcinoma of the cecum, stage pT3N1M0, treated ten years before with right hemicolectomy and adjuvant chemotherapy (Capecitabine and Bevacizumab). She developed painless obstructive jaundice of sudden onset. Computed tomography (CT) showed an ampullary nodule with secondary dilatation of the biliary and the pancreatic ducts. Subsequent duodenoscopy and endoscopic ultrasound identified the presence of multiple 3-10 mm tumor-like nodules from the first to the second duodenal knee, the largest one infiltrating the papillary area and preventing its cannulation. Biopsy revealed a moderately differentiated adenocarcinoma with cribriform, nidiform and acinar architectural patterns and positive immunohistochemistry for CK20 and CDX2, compatible with colon origin. The patient was treated with five cycles of chemotherapy (FOLFOX) with the disappearance of the duodenal nodules, although during follow-up she developed disease progression with a left adnexal metastasis with identical histological and immunohistochemical pattern.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"121-122"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139521827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comprehensive meta-analysis comparing the effectiveness and safety of cold snare polypectomy and hot snare polypectomy in removing colorectal polyps ≤ 10 mm. 一项综合荟萃分析比较了冷套扎息肉切除术和热套扎息肉切除术在切除 10 毫米以下大肠息肉方面的有效性和安全性。
IF 2.7 4区 医学
Revista Espanola De Enfermedades Digestivas Pub Date : 2025-02-01 DOI: 10.17235/reed.2024.10303/2024
Can Wu, Yujie Wang, Tao Shu, Zhongxin Sun, Li Liu, Xiaobin Sun
{"title":"A comprehensive meta-analysis comparing the effectiveness and safety of cold snare polypectomy and hot snare polypectomy in removing colorectal polyps ≤ 10 mm.","authors":"Can Wu, Yujie Wang, Tao Shu, Zhongxin Sun, Li Liu, Xiaobin Sun","doi":"10.17235/reed.2024.10303/2024","DOIUrl":"10.17235/reed.2024.10303/2024","url":null,"abstract":"<p><strong>Objective: </strong>The optimal methods for removing polyps remain controversial, especially for polyps ≤ 10 mm. We aim to combine the latest evidence to evaluate and compare the effectiveness and safety of cold snare polypectomy (CSP) and hot snare polypectomy (HSP) in the removal of colorectal polyps ≤ 10 mm in size.</p><p><strong>Methods: </strong>We performed an extensive search across multiple databases, including PubMed, Embase, Cochrane, and Web of Science, with the search period ending in April 2023, for randomized, controlled trials comparing the effectiveness and/or safety of CSP and HSP for the removal of ≤ 10 mm colorectal polyps. The final outcomes included complete resection rate, operation time, and postoperative adverse event (including immediate bleeding, delayed bleeding, and perforation) rates.</p><p><strong>Results: </strong>A total of 14 eligible randomized, controlled trials were included involving 7,460 patients and 15,829 polyps. The incidence of immediate bleeding was observed to be more prevalent in CSP in contrast to HSP, and the disparity was statistically notable (OR = 2.18, 95 % CI: 1.43-3.30, I2 = 36 %, p = 0.0003). The incidence of delayed bleeding was observed to be lower in CSP in contrast to HSP, and this difference was statistically significant (OR = 0.30, 95 % CI: 0.15-0.58, I2 = 0 %, p = 0.0003). Procedure time: both total colonoscopy time and specific polypectomy time were shorter in CSP versus HSP (MD = -5.92, 95 % CI: -9.70 to -2.14, I2 = 96 %, p = 0.002; MD = -0.56, 95 % CI: -0.91 to -0.20, I2 = 77 %, p = 0.002). There were no statistically significant differences in complete resection and polyp retrieval rate between CSP and HSP.</p><p><strong>Conclusion: </strong>CSP is as effective and safe as HSP for ≤ 10 mm colorectal polyps, while effectively reducing the risk of delayed bleeding and shortening procedure time.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"92-101"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141076725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inflammatory bowel disease secondary to treatment with ixekizumab in a patient with difficult-to-manage psoriasis. 一名难以控制的银屑病患者在接受ixekizumab治疗后继发炎症性肠病。
IF 2.7 4区 医学
Revista Espanola De Enfermedades Digestivas Pub Date : 2025-02-01 DOI: 10.17235/reed.2024.10290/2024
Eugenia Navarro Moreno, Marta Lázaro Sáez, José Luis Vega Sáenz
{"title":"Inflammatory bowel disease secondary to treatment with ixekizumab in a patient with difficult-to-manage psoriasis.","authors":"Eugenia Navarro Moreno, Marta Lázaro Sáez, José Luis Vega Sáenz","doi":"10.17235/reed.2024.10290/2024","DOIUrl":"10.17235/reed.2024.10290/2024","url":null,"abstract":"<p><p>Both psoriasis and inflammatory bowel disease (IBD) are immunomediated diseases. Some of their therapeutic tools are monoclonal antibodies. Ixekizumab is an interleukin-17 (IL-17) inhibitor approved for the treatment of psoriasis. Cases of IBD onset have been reported in patients treated with this drug. We present the case of a 35-year-old patient with the onset of ulcerative colitis (UC) type of IBD after starting ixekizumab treatment.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"113-114"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139723819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Colonic muco-submucosal elongated polyp misdiagnosed as an inverted colonic diverticulum. 一例被误诊为倒置结肠憩室（ICD）的结肠粘膜下拉长息肉（CMSEP）。
IF 2.7 4区 医学
Revista Espanola De Enfermedades Digestivas Pub Date : 2025-02-01 DOI: 10.17235/reed.2024.10153/2023
Yimin Ma, Kangwei Zhang, Youhong Cao
{"title":"Colonic muco-submucosal elongated polyp misdiagnosed as an inverted colonic diverticulum.","authors":"Yimin Ma, Kangwei Zhang, Youhong Cao","doi":"10.17235/reed.2024.10153/2023","DOIUrl":"10.17235/reed.2024.10153/2023","url":null,"abstract":"<p><p>Colonic muco-submucosal elongated polyp is a large intestine polyp with a long and broad stalk and a \"worm-like\" appearance which is covered by normal mucosa. The submucosal layer consists of edematous and fibrotic interstitium, adipose tissue, dilated blood vessels, and lymphatic follicles. Endoscopic magnification of the mucosal surface showed a uniform honeycomb pattern of regular colonic muco-submucosal elongated polyp vessels, with soft and deformable \"folds\" and \"gyrus\" at the top. The exact pathogenesis of CMSEP is still unclear.</p>","PeriodicalId":21342,"journal":{"name":"Revista Espanola De Enfermedades Digestivas","volume":" ","pages":"108"},"PeriodicalIF":2.7,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139417911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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