Rheumatology International最新文献_第3页

Tapering strategies for immunosuppressive, corticosteroid, and biologic therapy in lupus nephritis: a national survey of rheumatology and nephrology practices in Saudi Arabia. 免疫抑制、皮质类固醇和狼疮肾炎生物治疗的逐渐减少策略：沙特阿拉伯风湿病学和肾脏病学实践的全国调查。

IF 2.9 3区医学

Rheumatology International Pub Date : 2026-03-24 DOI: 10.1007/s00296-026-06106-3

Roaa Aljohani, Fahidah Alenzi, Alaa Alem, Jawaher Aljabri, Samar Alharbi

{"title":"Tapering strategies for immunosuppressive, corticosteroid, and biologic therapy in lupus nephritis: a national survey of rheumatology and nephrology practices in Saudi Arabia.","authors":"Roaa Aljohani, Fahidah Alenzi, Alaa Alem, Jawaher Aljabri, Samar Alharbi","doi":"10.1007/s00296-026-06106-3","DOIUrl":"10.1007/s00296-026-06106-3","url":null,"abstract":"The optimal duration of immunosuppressive (IS) therapy in lupus nephritis (LN) remains unclear, and tapering strategies for IS, corticosteroids (CS), and biologic therapies vary in practice. This study aimed to compare these practices between nephrologists and rheumatologists in Saudi Arabia and to examine factors influencing tapering decisions. We conducted a national cross-sectional 28-item online survey among nephrologists and rheumatologists involved in LN management across Saudi Arabia. A total of 142 physicians participated, evenly divided between the two specialties. Both groups reported that sustained clinical remission, stable renal function, and absence of recent flares were key criteria for tapering. Rheumatologists used the SLEDAI-2 K more frequently than nephrologists for readiness assessment (35.2% vs. 5.6%, p < 0.001) and post-taper monitoring (47.9% vs. 11.3%), whereas nephrologists more often considered repeat kidney biopsy before tapering (25.4% vs. 8.5%, p = 0.006). Rheumatologists predominantly tapered CS first (97.2% vs. 64.8%, p < 0.001). Most physicians initiated IS dose reduction within one year after sustained remission. In adjusted analyses accounting for practice context, nephrologists were less likely to taper CS first (adjusted OR 0.10) or rely on the SLEDAI-2 K (adjusted OR 0.09), but were more likely to delay IS withdrawal, favoring prolonged maintenance before discontinuation (adjusted OR 6.47), and to opt for immediate biologic discontinuation (adjusted OR 7.54). Disease flare was the most commonly reported challenge, with nearly half of physicians re-initiating the same induction therapy. Tapering practices for IS, CS, and biologic therapies in LN differ substantially between specialties, highlighting the need for harmonized, multidisciplinary tapering strategies.","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"46 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147514479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correction to: Rheumatoid vasculitis presenting in the absence of rheumatoid arthritis: a case-based review. 修正：在没有类风湿关节炎的情况下出现类风湿血管炎：一项基于病例的回顾。

IF 2.9 3区医学

Rheumatology International Pub Date : 2026-03-23 DOI: 10.1007/s00296-026-06092-6

David A J Cromie, Sarah K Stewart, Gary D Wright, Estelle G Healy

引用次数: 0

Systemic lupus erythematosus-related infections in pregnancy: a cross-sectional bibliometric analysis. 妊娠期系统性红斑狼疮相关感染：横断面文献计量学分析。

IF 2.9 3区医学

Rheumatology International Pub Date : 2026-03-23 DOI: 10.1007/s00296-026-06086-4

Dinara Yerlanova, Maidan Mukhamediyarov, Olena Zimba, Mariusz Korkosz, Burhan Fatih Kocyigit

引用次数: 0

Beyond anti-SSA and anti-SSB. The clinical significance of new antibodies in the diagnosis of Sjögren disease. 除了反ssa和反ssb。新抗体在Sjögren疾病诊断中的临床意义。

IF 2.9 3区医学

Rheumatology International Pub Date : 2026-03-21 DOI: 10.1007/s00296-026-06091-7

Aleksandra Okoń, Joanna Makowska, Olga Brzezińska

引用次数: 0

Remission and treatment persistence during sequential therapy in rheumatoid arthritis: results from the Estonian Biologic Treatment Registry. 缓解和治疗持续在序贯治疗类风湿关节炎：结果从爱沙尼亚生物治疗登记处。

IF 2.9 3区医学

Rheumatology International Pub Date : 2026-03-21 DOI: 10.1007/s00296-026-06097-1

Katrin Ulst, Sigrid Vorobjov, Karin Laas, Raili Müller

引用次数: 0

Infrared thermography in the detection of arthritis: a systematic review of diagnostic performance compared with joint ultrasound. 红外热成像在关节炎检测中的应用：与关节超声诊断性能比较的系统综述。

IF 2.9 3区医学

Rheumatology International Pub Date : 2026-03-12 DOI: 10.1007/s00296-026-06093-5

Julian Bastelberger, Marina Clasen, Christian Geber, Martin Offenbächer, Rebecca Hasseli, Gabriel Dias Rodrigues, Andreas Schwarting, Konstantinos Triantafyllias

引用次数: 0

Correction: MRI-guided muscle biopsy improves diagnostic yield in small- to medium-vessel vasculitis: a retrospective single-center study. 更正：mri引导下的肌肉活检提高了中小血管炎的诊断率：一项回顾性单中心研究。

IF 2.9 3区医学

Rheumatology International Pub Date : 2026-03-12 DOI: 10.1007/s00296-026-06080-w

Soma Fukami, Shin-Ichiro Ohmura, Takayuki Masui, Yoshiro Otsuki, Toshitaka Yukishima, Haruka Yonezawa, Yusuke Ohkubo, Toshiaki Miyamoto, Kumiko Shimoyama

引用次数: 0

Calprotectin and serum amyloid A for disease activity assessment in giant cell arteritis and polymyalgia rheumatica: results from a prospective single-centre cohort study. 钙保护蛋白和血清淀粉样蛋白A用于巨细胞动脉炎和风湿性多肌痛的疾病活动性评估：一项前瞻性单中心队列研究的结果

IF 2.9 3区医学

Rheumatology International Pub Date : 2026-03-04 DOI: 10.1007/s00296-026-06081-9

Marc Schmalzing, Matthias Froehlich, Patrick P Strunz, Konstanze V Guggenberger, Ottar Gadeholt, Rudolf A Werner, Hannah Labinsky, Jan Portegys, Marcus Dittrich, Thorsten A Bley, Tobias Mueller, Michael Gernert

引用次数: 0

Blood biomarkers of inflammation and brain-derived neurotrophic factor can not be used to assess the effectiveness of collagen mesotherapy in chronic cervical myofascial pain syndrome. A pilot single-blind randomized study. 炎症和脑源性神经营养因子的血液生物标志物不能用于评估胶原疗法对慢性颈肌筋膜疼痛综合征的疗效。一项试点单盲随机研究。

IF 2.9 3区医学

Rheumatology International Pub Date : 2026-03-02 DOI: 10.1007/s00296-026-06094-4

Kamil Koszela, Agnieszka Paradowska-Gorycka, Brygida Kwiatkowska, Marta Woldańska-Okońska, Barbara Stypińska, Adam Ejma-Multański, Robert Gasik

{"title":"Blood biomarkers of inflammation and brain-derived neurotrophic factor can not be used to assess the effectiveness of collagen mesotherapy in chronic cervical myofascial pain syndrome. A pilot single-blind randomized study.","authors":"Kamil Koszela, Agnieszka Paradowska-Gorycka, Brygida Kwiatkowska, Marta Woldańska-Okońska, Barbara Stypińska, Adam Ejma-Multański, Robert Gasik","doi":"10.1007/s00296-026-06094-4","DOIUrl":"10.1007/s00296-026-06094-4","url":null,"abstract":"Recent years have seen a marked increase in the number of patients diagnosed with spinal disorders, including chronic cervical myofascial pain syndrome (CMPS). This article aims to explore the potential of inflammatory process biomarkers in the blood and brain-derived neurotrophic factor (BDNF) as a means to assess the efficacy of collagen mesotherapy in the management of chronic CMPS. The second objective of this article is to evaluate the safety of collagen mesotherapy in chronic CMPS. The study comprised 23 subjects, who were randomly assigned either to the collagen mesotherapy group (n = 11) or the lignocaine mesotherapy group (n = 12). Blood was collected from each patient, and also the subjects were evaluated with the numerical rating scale (NRS) and the neck disability index (NDI). Results Both collagen and lignocaine mesotherapy have been observed to cause a significant reduction in pain intensity (NRS) and disability (NDI) over time, with no significant differences seen between the two interventions. However, the fluctuations in the levels of inflammatory biomarkers (TNFα, IL-1β, IL-6) and BDNF did not correspond with the clinical improvement noted. No adverse events related to the intervention were also observed. The potential of inflammatory biomarkers and BDNF, when assessed in blood serum, to serve as a basis for evaluating the efficacy of collagen mesotherapy in chronic CMPS; remains to be elucidated. Nevertheless, collagen mesotherapy appears to be an effective and safe treatment for chronic CMPS. However, further research in this area is required. Trial registration: NCT06807177. https//clinicaltrials.gov/study/NCT06807177.","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"46 3","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147326982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Behçet's disease occurred after brodalumab initiation in a patient with chronic non-bacterial osteitis: a case-based literature review. 慢性非细菌性骨炎患者在布罗达鲁单抗起始治疗后发生behet病：一项基于病例的文献综述。

IF 2.9 3区医学

Rheumatology International Pub Date : 2026-03-02 DOI: 10.1007/s00296-026-06096-2

Koji Suzuki, Mitsuhiro Akiyama, Koichi Saito, Yuko Kaneko

引用次数: 0