{"title":"Comparative evaluation of large language model-based AI platforms for radiographic assessment in rheumatoid arthritis.","authors":"Yerlan Yemeshev, Bekaidar Nurmashev, Maidan Mukhamediyarov","doi":"10.1007/s00296-026-06103-6","DOIUrl":"10.1007/s00296-026-06103-6","url":null,"abstract":"","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"46 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147623721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical presentation and rehabilitation approaches in patients with ankylosing spondylitis and comorbidities: a multicenter retrospective study.","authors":"Ainur Issakulova, Maidan Mukhamediyarov","doi":"10.1007/s00296-026-06098-0","DOIUrl":"10.1007/s00296-026-06098-0","url":null,"abstract":"<p><p>Ankylosing spondylitis (AS) is a chronic immune-mediated disease characterized by damage to the axial skeleton and a high prevalence of comorbidities that influence disease severity and rehabilitation strategy. Rehabilitation strategies in AS patients with comorbidities are scarcely examined. The aim of this study was to examine the influence of comorbidities on clinical presentation, disease activity, and rehabilitation strategies in AS. A retrospective multicenter study was conducted in three rheumatology centers from January 1st to December 31st, 2023. The study included patients aged above 18 with existing X-ray lesions of the axial skeleton and comorbidities. Demographic, clinical, and radiological data were recorded. The statistical analysis included descriptive data. The normality of distribution for continuous variables was assessed using the Shapiro-Wilk test. Comparisons between groups were assessed using the Mann-Whitney U test. The Chi-square test was used for categorical data. A significance threshold was set at P < 0.05. Of 148 examined patients with AS, 59 (39.8%) had comorbidities. Arterial hypertension (n = 33, 55.9%), osteoporosis/osteopenia (n = 12, 20.3%), and diabetes mellitus (n = 10, 16.9%), were among the most frequent comorbidities. Disease activity indices were moderate (Mean BASDAI = 4.7; Mean ASDAS = 2.5); there were no significant differences between patients with and without comorbidities. Patients with comorbidities presented with extensive axial damage involving all parts of the spine (p = 0.021). Swimming (n = 26, 44.1%), low-intensity physical activity therapy (n = 18, 30.5%), massage (n = 14, 23.7%), and lumbar orthosis (n = 8, 13.6%) were recommended for patients with comorbidities. Rehabilitation approaches, including swimming are frequently recommended to stabilize symptoms in patient with AS.</p>","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"46 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147623744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The effect of structured hand massage on hand function and grip strength in rheumatoid arthritis patients: a randomized controlled pilot study.","authors":"Umida Khojakulova, Gülşah Yaşa Öztürk, Burak Okyar, Olena Zimba, Burhan Fatih Kocyigit","doi":"10.1007/s00296-026-06095-3","DOIUrl":"10.1007/s00296-026-06095-3","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to assess the impact of a 10-session hand massage protocol on hand function, grip strength, pinch strength, pain threshold, and tactile sensory threshold in patients with early-stage, seropositive rheumatoid arthritis (RA) without radiographic damage or hand deformity.</p><p><strong>Methods: </strong>This study was a randomized controlled clinical trial. Thirty female RA patients with a diagnosis time of less than two years, seropositive, with low disease activity/remission, and without active arthritis in their hands were included in the study. Participants were randomized 1:1 to intervention and control groups. The intervention group underwent 10 hand massage sessions over a two-week period, in addition to regular medical care. The control group received only regular medical care. All assessments were performed at baseline (T1) and at week 2 (T2). Outcome measures included hand grip strength, pinch strength, pain threshold (dolorimetry), tactile sensory threshold (Semmes-Weinstein monofilament test), Duruöz Hand Index (DHI), and patient global assessment (PGA).</p><p><strong>Results: </strong>A total of 30 RA patients were included in the study (intervention group, n = 15; control group, n = 15). At baseline, no significant differences were observed between the groups in demographic, laboratory, or clinical characteristics (p > 0.05). In the intervention group, significant improvements in hand grip strength and pinch force were observed at T2 compared with baseline (p = 0.008 and p = 0.023, respectively). Median hand grip strength increased from 55 (40-75) to 65 (45-80) kg, and median pinch strength increased from 15 (6-18) to 16 (11-21) kg. No significant alterations were noted in these parameters within the control group (p > 0.05). In the control group, median hand grip strength was 45 (25-80) kg at baseline and 45 (20-80) kg at week 2, while median pinch strength was 14 (6-18) kg at baseline and 14 (5-19) kg at week 2. In the intervention group, significant reductions in DHI and PGA scores were recorded at the end of therapy (p = 0.005 and p = 0.001, respectively). No significant differences were noted in DHI and PGA levels in the control group (p > 0.05). Moreover, median PGA scores were significantly lower in the intervention group than in the control group at T2 (4 [2-5] vs. 5 [3-6]; p < 0.001). No significant changes were found in dolorimeter and touch sensory thresholds in either group (p > 0.05).</p><p><strong>Conclusion: </strong>Hand massage interventions for patients with RA enhance grip strength, hand function, and overall patient evaluations. No effect on pain or tactile thresholds was observed. Further studies with larger sample sizes and longer follow-up periods are required to corroborate these findings.</p>","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"46 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13050759/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147623665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Saltanat K Yerkebayeva, Meirgul I Assylbek, Olena Zimba, Yuliya Fedorchenko, Ahmet Usen
{"title":"Stroke in autoimmune rheumatic diseases.","authors":"Saltanat K Yerkebayeva, Meirgul I Assylbek, Olena Zimba, Yuliya Fedorchenko, Ahmet Usen","doi":"10.1007/s00296-026-06110-7","DOIUrl":"10.1007/s00296-026-06110-7","url":null,"abstract":"","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"46 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13050762/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147623737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Suade Özlem Badak, Neslihan Gökçen, Emrah Koç, Sevgül Kara Köse, Eren Erken
{"title":"Heel fat pad atrophy correlates with cutaneous fibrosis severity but not functional disability in systemic sclerosis: a single-center, cross-sectional, hypothesis-generating study.","authors":"Suade Özlem Badak, Neslihan Gökçen, Emrah Koç, Sevgül Kara Köse, Eren Erken","doi":"10.1007/s00296-026-06109-0","DOIUrl":"10.1007/s00296-026-06109-0","url":null,"abstract":"","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"46 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147594489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Eleni C Pardali, Katerina Maria Kontouli, Arriana Gkouvi, Myrto Samara, Odysseas Androutsos, Christina G Katsiari, Dimitrios G Goulis, Dimitrios P Bogdanos, Maria G Grammatikopoulou
{"title":"Systemic lupus erythematosus is associated with an increased risk for orthorexia nervosa: a cross-sectional study.","authors":"Eleni C Pardali, Katerina Maria Kontouli, Arriana Gkouvi, Myrto Samara, Odysseas Androutsos, Christina G Katsiari, Dimitrios G Goulis, Dimitrios P Bogdanos, Maria G Grammatikopoulou","doi":"10.1007/s00296-026-06107-2","DOIUrl":"10.1007/s00296-026-06107-2","url":null,"abstract":"","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"46 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13038785/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147594412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Panagiota Anyfanti, Christina Antza, Konstantinos Tragiannidis, Andrej Belančić, Yusuf Ziya Şener, Andrea Katrin Faour, Alexandra Ainatzoglou, Elena Angeloudi, Evangelia Chaida, Theodoros Dimitroulas, Vasilios Kotsis
{"title":"Sodium and potassium intake in rheumatoid arthritis: a systematic review of clinical studies with implications for disease-related outcomes.","authors":"Panagiota Anyfanti, Christina Antza, Konstantinos Tragiannidis, Andrej Belančić, Yusuf Ziya Şener, Andrea Katrin Faour, Alexandra Ainatzoglou, Elena Angeloudi, Evangelia Chaida, Theodoros Dimitroulas, Vasilios Kotsis","doi":"10.1007/s00296-026-06104-5","DOIUrl":"10.1007/s00296-026-06104-5","url":null,"abstract":"","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"46 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13038458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147594456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Analysis of YouTube videos on rheumatic diseases and pregnancy: a cross-sectional study.","authors":"Dinara Yerlanova, Olena Zimba, Umida Khojakulova, Marlen Yessirkepov, Burhan Fatih Kocyigit","doi":"10.1007/s00296-026-06102-7","DOIUrl":"10.1007/s00296-026-06102-7","url":null,"abstract":"","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"46 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13032928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147575253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Maria Soura, Amalia Bakiri, George E Fragoulis, Konstantinos D Vassilakis
{"title":"Glucocorticoid-induced diabetes mellitus: mechanisms, risk factors, and clinical pathways with insights from autoimmune rheumatic diseases.","authors":"Maria Soura, Amalia Bakiri, George E Fragoulis, Konstantinos D Vassilakis","doi":"10.1007/s00296-026-06099-z","DOIUrl":"10.1007/s00296-026-06099-z","url":null,"abstract":"","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"46 4","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13017998/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147514493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}