Rheumatology International最新文献

{"title":"Long-term changes in Sjögren's disease: a 9-year prospective follow-up study from the SJOGRENSER Registry.","authors":"Mónica Fernández-Castro, Zulema Plaza-Almuedo, Jose Rosas, Victor Martínez-Taboada, Alejandro Olivé, Raúl Menor-Almagro, Belen Serrano-Benavente, Judit Font-Urgelles, Angel García-Aparicio, Sara Manrique-Arija, Jesus Alberto García-Vadillo, Ruth López-González, Javier Narváez, Beatriz Rodriguez-Lozano, Carlos Galisteo, Jorge González-Martín, Paloma Vela-Casasempere, Cristina Bohórquez, Celia Erausquin, Beatriz Paredes-Romero, Leyre Riancho-Zarrabeitia, Sheila Melchor-Diaz, Jose Maria Pego-Reigosa, Sergi Heredia, Clara Moriano, Maria Angeles Blazquez-Cañamero, Paula Estrada, Enrique Júdez, Joaquín María Belzunegui, Consuelo Ramos, Fernando Sánchez-Alonso, Jose Luis Andreu","doi":"10.1007/s00296-025-05909-0","DOIUrl":"https://doi.org/10.1007/s00296-025-05909-0","url":null,"abstract":"<p><p>The objective of SjögrenSER Prospective (SjD-PROS) was to evaluate the improvement, stability or progression of SjD in clinical practice. SjD-PROS is an observational, longitudinal, multicenter study of SjD in Spain. Participants from the prior transversal phase were invited to a follow-up visit after 9.5 years. Data were collected via interviews and medical records. Variables were analyzed using means, medians and frequencies. Statistical associations were assessed using T student test, Kruskal-Wallis and the Chi-square test. We included 314 patients, 95% women (mean age of 66 years; mean disease duration of 17 years). At follow-up visit, the most frequent systemic manifestations were arthralgias (54%) and hematological involvement (49%), with arthralgias being significantly less frequent than at baseline visit (p < 0.001); the most affected organs were the lung (15.6%) and the kidney (11.5%). Half of the patients in SjD-PROS, had positive rheumatoid factor, 16% less than at baseline visit; β2-microglobulin was significantly elevated compared to baseline visit (62.5%, p < 0.001). Articular, pulmonary, hematological and biological domains of ESSDAI index showed the greatest changes, both in improvement and worsening, and the greatest activity. Systemic treatments use was significantly higher in patients showing activity in ESSDAI. This study offers valuable insights into the most variable clinical and serological manifestations throughout the course of SjD. ESSDAI domains showing the greatest changes reflected the greatest treatments needs. These findings allow for patient stratification based on phenotype, a crucial step in designing follow-up protocols.</p>","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"45 7","pages":"156"},"PeriodicalIF":3.2,"publicationDate":"2025-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144317841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validity and psychometric characteristics of the psoriatic arthritis quality of life (PSAQoL) questionnaire in the Turkish population.","authors":"Mehmet Tuncay Duruöz, Kemal Nas, Sevtap Acer Kasman, Emre Uzun, Halise Hande Gezer","doi":"10.1007/s00296-025-05911-6","DOIUrl":"10.1007/s00296-025-05911-6","url":null,"abstract":"<p><p>The aim of this study was to translate and culturally validate the Psoriatic Arthritis Quality of Life Questionnaire (PsAQoL) into Turkish and to evaluate its reliability and validity in patients with psoriatic arthritis (PsA). A total of 162 PsA patients diagnosed according to CASPAR criteria were recruited from two rheumatology clinics. The PsAQoL was translated and culturally adapted into Turkish using a standardized forward-backward translation method. Internal consistency was assessed using Cronbach's alpha. Construct validity was evaluated by correlating PsAQoL scores with quality of life (SF-36), functional (HAQ), emotional (HADS), and clinical disease activity indices (DAPSA, BASDAI, DAS28). The Turkish version of the PsAQoL was found to be clear, concise, and well understood by patients. The average time to complete the questionnaire was 3.3 ± 0.9 min. Internal consistency was good (Cronbach's α = 0.930). Strong correlations were found with SF-36 physical (r = - 0.744) and mental components (r = - 0.731), indicating convergent validity. Moderate correlations were observed with HAQ (r = 0.533), VAS pain (r = 0.408), HADS-Anxiety (r = 0.535), and HADS-Depression (r = 0.517), while correlations with unrelated clinical parameters such as age and PASI were weak or insignificant, indicating divergent validity. No floor or ceiling effects were detected, and there were no missing responses. The Turkish version of the PsAQoL is a valid, reliable, and practical tool for assessing disease-specific quality of life in PsA. Its ease of use and psychometric strength support its application in both clinical practice and researchs.</p>","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"45 7","pages":"155"},"PeriodicalIF":3.2,"publicationDate":"2025-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12170716/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144302795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimating pain visual analogue scale from health assessment questionnaire for rheumatoid arthritis with beta mixture models.","authors":"Sean P Gavan, Sainan Chang, Felice Rivellese, Zoë Ide, Michael Stadler, Katherine Payne, Darren Plant, Anne Barton, Costantino Pitzalis","doi":"10.1007/s00296-025-05897-1","DOIUrl":"10.1007/s00296-025-05897-1","url":null,"abstract":"<p><p>To map from the health assessment questionnaire disability index (HAQ) to the pain visual analogue scale (VAS) for people with rheumatoid arthritis. The estimation sample comprised adults with rheumatoid arthritis and inadequate response to tumour necrosis factor-α inhibitors in a multicentre phase 4 randomised controlled trial. Beta mixture models were estimated with combinations of HAQ and its square, age and sex as independent variables. Bayesian Information Criteria informed the number of components. Model performance (root mean squared error; mean absolute error; pseudo-R²) was estimated by k-fold cross validation. Graphs illustrated mean observed and predicted pain VAS, and cumulative distribution of observed and simulated pain VAS values. For face validity, a probabilistic analysis simulated 5000 pain VAS values at four HAQ scores. For external validation, the performance of the preferred specification was assessed using the Rheumatoid Arthritis Medication Study cohort. There were 1055 observations from 158 participants in the estimation sample (mean age: 55.8; 81% female; mean HAQ: 1.72). The preferred specification was a two-component beta mixture model (probability variables: HAQ, age, sex; main regression variable: HAQ). Visual plots illustrated good fit across the HAQ distribution, and a similar cumulative distribution of observed and predicted pain VAS values. Probabilistic analysis demonstrated that the preferred specification handled uncertainty appropriately. External validation demonstrated that the preferred specification performed well in an independent dataset. Beta mixture models provide accurate non-linear estimates of pain VAS from HAQ scores to support evidence synthesis and resource allocation decision-making for people with rheumatoid arthritis.</p>","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"45 7","pages":"154"},"PeriodicalIF":3.2,"publicationDate":"2025-06-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12167326/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144294864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Self-compassion, emotion regulation, and resilience as predictors of psychological well-being in fibromyalgia patients: a cross-sectional study.","authors":"İbrahim Hakkı Karakuş, Erdoğdu Akça, Mehmet Tuncay Duruöz, Kemal Sayar","doi":"10.1007/s00296-025-05905-4","DOIUrl":"10.1007/s00296-025-05905-4","url":null,"abstract":"<p><p>While the roles of self-compassion and cognitive emotion regulation in mental health are increasingly acknowledged, their specific impact on fibromyalgia (FM) remains understudied. Given the substantial psychological burden associated with FM, this study aimed to examine these constructs in relation to emotional distress and resilience. Specifically, we sought to: (1) compare self-compassion and emotion regulation strategies between FM patients and healthy controls; (2) explore their associations with depression, anxiety, pain intensity, and resilience; and (3) identify predictors of psychological distress, focusing on self-compassion and emotion regulation. The study included 160 participants (80 FM patients and 80 age- and gender-matched healthy controls) who completed validated instruments, including the Self-Compassion Scale (SCS), Cognitive Emotion Regulation Questionnaire (CERQ), Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Toronto Alexithymia Scale (TAS-20), Brief Resilience Scale (BRS), and Visual Analog Scale (VAS). Group comparisons were conducted using Student's t tests. Pearson correlations assessed associations among psychological variables. Mediation analyses, performed using PROCESS macro with 5000 bootstrap resamples, tested whether resilience mediated the relationships between self-compassion and clinical outcomes. FM patients reported significantly lower self-compassion and greater use of maladaptive emotion regulation strategies-particularly rumination and catastrophizing-compared to healthy controls (p < 0.001). Self-compassion was negatively correlated with depression and anxiety, while resilience was positively associated with self-compassion and inversely related to psychological distress. Regression analyses showed that self-compassion, rumination, catastrophizing, resilience, and pain intensity significantly predicted depression and anxiety. Resilience mediated the relationship between self-compassion and  both depressive and anxiety symptoms, though no significant mediation was observed for pain intensity. FM patients experience heightened psychological distress, characterized by reduced self-compassion and increased use of maladaptive emotion regulation strategies. Self-compassion and emotion regulation emerged as key predictors of depression and anxiety, with resilience playing a mediating role in depressive symptoms. These findings underscore the potential of interventions that cultivate self-compassion and strengthen adaptive emotion regulation to improve psychological well-being in individuals with FM and support a more integrative approach to treatment.</p>","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"45 7","pages":"153"},"PeriodicalIF":3.2,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12158836/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144275766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Late-onset rheumatoid arthritis: clinical features, diagnostic challenges, and treatment approaches.","authors":"Olena Zimba, Chokan Baimukhamedov, Burhan Fatih Kocyigit","doi":"10.1007/s00296-025-05908-1","DOIUrl":"10.1007/s00296-025-05908-1","url":null,"abstract":"<p><p>Late-Onset Rheumatoid Arthritis (LORA) is receiving increased clinical attention due to global aging trends. LORA presents distinct diagnostic, clinical, and therapeutic challenges. It often presents with a balanced gender distribution, acute onset, preferential involvement of larger joints, and decreased seropositivity. The diagnostic process is complex due to atypical presentations, comorbidities, and limitations of classification criteria, which insufficiently address the heterogeneity of LORA phenotypes. Patients with LORA often experience age-related geriatric syndromes, including frailty, cognitive decline, and malnutrition, in addition to comorbid cardiovascular disorders, pulmonary involvement, oncologic conditions, and osteoporosis. All these factors confound disease progression and treatment strategies, necessitating careful consideration of polypharmacy and modified drug metabolism. While the treatment principles largely align with those of Younge-Onset Rheumatoid Arthiritis (YORA), LORA management requires individualized approaches. Available evidence suggests that with proper monitoring, disease-modifying anti-rheumatic drugs (DMARDs) are safe and effective for older adults. Glucocorticoids should be minimized due to potential detrimental effects. Despite elevated baseline disease activity and functional deterioration, effectively managed LORA patients may achieve disease control similar to that of younger individuals. This review advocates for age-adjusted diagnostic strategies and patient-centered care models tailored to the needs of older RA patients. Addressing these unmet needs may enhance outcomes and quality of life for the growing population of LORA patients.</p>","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"45 6","pages":"152"},"PeriodicalIF":3.2,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149268/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144249377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and risk factors of renal involvement in seronegative spondyloarthropathies: a systematic review.","authors":"Kinga M Tyczyńska, Jerzy Świerkot","doi":"10.1007/s00296-025-05907-2","DOIUrl":"10.1007/s00296-025-05907-2","url":null,"abstract":"<p><p>Seronegative spondyloarthritis (SpA) comprises a heterogeneous group of rheumatic diseases characterized by axial and peripheral joint involvement, as well as extra-articular manifestations, including uveitis, psoriasis, and inflammatory bowel disease. Although renal involvement in SpA is less understood, evidence suggests it may result from disease activity, chronic inflammation, or therapeutic agents. The underlying pathophysiology remains unclear. This systematic review evaluates the prevalence and risk factors associated with renal abnormalities in SpA. A systematic literature search was conducted following the latest Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Data from 26 studies published between 1980 and 2025 were synthesized. Extracted variables included study author, year and location of publication, sample size, renal assessment parameters, prevalence of renal involvement, presence of control groups, and statistical significance of findings. Renal involvement in SpA, assessed through hematuria, proteinuria, estimated glomerular filtration rate, and International Classification of Diseases codes, showed considerable variability, with prevalence ranging from 0.2 to 77.5%. Nephrolithiasis was also more common among SpA patients, with reported rates between 1.6% and 29.1%. Potential risk factors, including age, disease activity, comorbidities, and HLA-B27 status, were explored, though findings remained inconsistent. This review highlights significant methodological discrepancies among studies assessing renal involvement in SpA. Further research is needed to clarify the renal complications associated with SpA and establish reliable risk factors. PROSPERO Registration: CRD42024579791.</p>","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"45 6","pages":"151"},"PeriodicalIF":3.2,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145282/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144249378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Global practice guidelines in rheumatology: a cross-sectional altmetric and citation analysis.","authors":"Olena Zimba, Mariusz Korkosz, Fatima Alnaimat, George E Fragoulis, Marlen Yessirkepov, Chokan Baimukhamedov, Burhan Fatih Kocyigit","doi":"10.1007/s00296-025-05899-z","DOIUrl":"10.1007/s00296-025-05899-z","url":null,"abstract":"<p><p>Clinical practice guidelines are instrumental for managing rheumatic diseases, which are often chronic, multifaceted, and require evidence-based diagnostic and therapeutic approaches. This study assessed the societal and academic implications of global rheumatology practice guidelines. A cross-sectional altmetric and citation analysis was conducted to assess the implications of rheumatology practice guidelines. Practice guidelines published in Annals of the Rheumatic Diseases and Arthritis & Rheumatology (2000-2024) were retrieved through PubMed searches. A total of 127 guidelines were included in this study. On April 9, 2025, the Altmetric Attention Score (AAS), Mendeley bookmarking data, and citation metrics from the Scopus and Dimensions databases were recorded for each document. A significant rise in the volume of published guidelines over time was detected (p < 0.001 for the trend). Guidelines in Annals of the Rheumatic Diseases attracted more Scopus citations (median: 320) compared to Arthritis & Rheumatology (median: 145.5; p = 0.046); AAS values did not show a significant difference between the sources (p = 0.168). The analysis demonstrated statistically significant positive correlations between Scopus citation counts and several altmetric indices, including AAS, news outlets, and Facebook mentions, and Mendeley bookmarking counts (all p < 0.001). No correlations recorded for X (Twitter) mentions. This study reveals the implications of global rheumatology practice guidelines in view of their traditional and alternative metrics. To maximize the societal implications, renewed social media strategies are warranted to expand online visibility and academic outreach of global rheumatology practice guidelines.</p>","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"45 6","pages":"150"},"PeriodicalIF":3.2,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12141108/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144226412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social media in myositis care - an exploratory mixed-methods study among myositis patients (SociMyo).","authors":"Katharina Boy, Niklas Ohm, Susann May, Greta Nordmann, Lynn Wilson, Johannes Knitza, Martin Heinze, Latika Gupta, Felix Muehlensiepen","doi":"10.1007/s00296-025-05903-6","DOIUrl":"10.1007/s00296-025-05903-6","url":null,"abstract":"<p><p>Myositis is a rare autoimmune disease primarily affecting muscles, with potential involvement of the skin, heart, and lungs. Patients often experience delays in diagnosis, lack of adequate information, and limited support for disease management. Social media has emerged as a valuable tool to address these gaps by facilitating information exchange, peer support, and community building. However, its role in myositis care is not yet well understood. This study aims to explore how myositis patients use social media, focusing on shared content, perceived benefits and challenges, and the overall impact on disease management and emotional well-being. A mixed-methods approach was applied, including semi-structured interviews with 11 patients and a netnographic analysis of social media group dedicated to myositis care. Data were analyzed using Kuckartz's structured qualitative content analysis, with coding performed inductively, to identify key themes. Four key themes emerged: (I) Social media as a global platform for sharing experiential knowledge, particularly on symptom management, medication side effects, and coping strategies. (II) Peer support fostering a sense of belonging, emotional exchange, and mutual encouragement through structured discussions and community-driven moderation. (III) Perceived benefits, such as real-time access to patient-driven insights, shared decision-making support, and enhanced communication with healthcare providers. (IV) Perceived drawbacks, including misinformation, privacy concerns, and the absence of professional medical input. Participants emphasized the need for expert involvement to improve content reliability, while also valuing the autonomy and emotional support within these communities. Social media platforms, particularly closed groups, provide a complementary avenue to traditional care by offering support and knowledge exchange. To maximize their potential, privacy concerns and the integration of professional guidance must be addressed.</p>","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"45 6","pages":"149"},"PeriodicalIF":3.2,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12137372/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potentials and barriers of digital patient education in rheumatic disease management: an exploratory qualitative interview study.","authors":"Franziska Lumma, Johannes Knitza, Felix Mühlensiepen","doi":"10.1007/s00296-025-05893-5","DOIUrl":"10.1007/s00296-025-05893-5","url":null,"abstract":"<p><p>Patient education (PE) is essential, however hindered by the limited time of rheumatology healthcare professionals. Digital patient education (DPE) promises to bridge this care gap. This study explores the potential and challenges of DPE in rheumatology. Semi-structured expert interviews were conducted with 14 stakeholders across healthcare levels, including rheumatologists, specialized nurses, patient representatives, policymakers, and industry experts. Data were analyzed using qualitative content analysis following Kuckartz's methodology, with intracoder reliability assessed via the Brennan-Prediger Kappa coefficient. Three main themes emerged in the qualitative content analysis: (1) the status quo of PE in general, (2) the potentials and challenges of DPE and (3) DiRhIS as an emerging tool in the field of DPE in rheumatology. Participants highlighted significant gaps in traditional PE, including limited consultation time, inadequate access to information, and misinformation risks. While DPE was recognized as a promising tool to enhance patient knowledge, adherence, and shared decision-making, systemic barriers hinder adoption. Experts identified key obstacles such as resistance among healthcare providers, limited digital literacy among patients, and challenges in integrating DPE into clinical workflows. A hybrid model combining digital and in-person education was favored to address patient needs across different literacy levels. Successful implementation requires structured integration, stakeholder involvement, and strategies to address infrastructural and attitudinal barriers. Digital patient education (DPE) has the potential to enhance accessibility and the quality of patient education in rheumatology. Findings emphasize the need for personalized patient education, where the balance between face-to-face and digital learning is adapted to individual preferences, health literacy levels, and accessibility needs.</p>","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"45 6","pages":"148"},"PeriodicalIF":3.2,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12137533/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144216777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and efficacy of IL-17 inhibitors in patients with comorbid multiple sclerosis/multiple Sclerosis-like syndrome: a systematic review.","authors":"Nikolaos Chaitidis, Grigorios T Sakellariou, Maria Daviti, Stavritsa Taxiarchoula Varvara, Michail Panagiotidis, Michael Arabatzis, Dimitra Kiritsi, Efstratios Vakirlis, Elena Sotiriou","doi":"10.1007/s00296-025-05902-7","DOIUrl":"10.1007/s00296-025-05902-7","url":null,"abstract":"","PeriodicalId":21322,"journal":{"name":"Rheumatology International","volume":"45 6","pages":"147"},"PeriodicalIF":3.2,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144209402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}