Prevalence and clinical severity of takayasu arteritis angiographic types: a systematic review with meta-analysis.

IF 2.9 3区 医学 Q2 RHEUMATOLOGY
Nikolaos Taprantzis, Dimosthenis Chrysikos, Amir Shihada, Theodore Troupis
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引用次数: 0

Abstract

Takayasu arteritis is a rare inflammatory disease that primarily affects medium- and large-sized arteries, particularly the aorta and its branches. The Hata classification defines six angiographic types based on the involved aortic segments. Clinical symptoms May vary depending on the distribution of arterial involvement. This systematic review and meta-analysis aimed to estimate the pooled prevalence of each angiographic type and evaluate their associations with clinical Manifestations.A systematic search of electronic databases was conducted to identify studies reporting angiographic classifications and clinical symptoms in patients with Takayasu arteritis. Pooled prevalence estimates were calculated using R software, including subgroup analyses by geographic area and imaging modality. Meta-regression was used to assess associations between angiographic types and specific clinical features.Type V was the most common angiographic subtype, with a pooled prevalence of 43.49%, while type III was the least common, 5.32%. Subgroup analyses showed statistically significant differences only for type IIb, based on modality types. Meta-regression revealed significant correlations between angiographic types and clinical symptoms, with Type V exhibiting the greatest severity, and types IIb and III the lowest.This meta-analysis highlights the varying distribution of angiographic types of Takayasu arteritis and their significant associations with clinical symptoms, which may guide prognostic and management strategies.

高松动脉炎血管造影类型的患病率和临床严重程度:一项系统综述和荟萃分析。
高须动脉炎是一种罕见的炎症性疾病,主要影响大中型动脉,特别是主动脉及其分支。Hata分类根据累及的主动脉段划分了六种血管造影类型。临床症状可能因动脉受累的分布而异。本系统综述和荟萃分析旨在估计每种血管造影类型的总患病率,并评估其与临床表现的关系。我们对电子数据库进行了系统的检索,以确定报道高须动脉炎患者的血管造影分类和临床症状的研究。使用R软件计算合并患病率估计值,包括按地理区域和成像方式进行亚组分析。meta回归用于评估血管造影类型与特定临床特征之间的关系。V型是最常见的血管造影亚型,总患病率为43.49%,而III型最少,为5.32%。亚组分析显示,基于模态类型,仅IIb型有统计学显著差异。meta回归显示血管造影类型与临床症状之间存在显著相关性,其中V型最严重,IIb和III型最低。本荟萃分析强调了高松动脉炎血管造影类型的不同分布及其与临床症状的显著相关性,这可能指导预后和管理策略。
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来源期刊
Rheumatology International
Rheumatology International 医学-风湿病学
CiteScore
7.30
自引率
5.00%
发文量
191
审稿时长
16. months
期刊介绍: RHEUMATOLOGY INTERNATIONAL is an independent journal reflecting world-wide progress in the research, diagnosis and treatment of the various rheumatic diseases. It is designed to serve researchers and clinicians in the field of rheumatology. RHEUMATOLOGY INTERNATIONAL will cover all modern trends in clinical research as well as in the management of rheumatic diseases. Special emphasis will be given to public health issues related to rheumatic diseases, applying rheumatology research to clinical practice, epidemiology of rheumatic diseases, diagnostic tests for rheumatic diseases, patient reported outcomes (PROs) in rheumatology and evidence on education of rheumatology. Contributions to these topics will appear in the form of original publications, short communications, editorials, and reviews. "Letters to the editor" will be welcome as an enhancement to discussion. Basic science research, including in vitro or animal studies, is discouraged to submit, as we will only review studies on humans with an epidemological or clinical perspective. Case reports without a proper review of the literatura (Case-based Reviews) will not be published. Every effort will be made to ensure speed of publication while maintaining a high standard of contents and production. Manuscripts submitted for publication must contain a statement to the effect that all human studies have been reviewed by the appropriate ethics committee and have therefore been performed in accordance with the ethical standards laid down in an appropriate version of the 1964 Declaration of Helsinki. It should also be stated clearly in the text that all persons gave their informed consent prior to their inclusion in the study. Details that might disclose the identity of the subjects under study should be omitted.
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