Revista espanola de cardiologia最新文献

{"title":"Espacios verdes urbanos y salud cardiovascular: del paisaje al impacto clínico","authors":"Julia Playán-Escribano , Inés Ramos González-Cristóbal , Adolfo Villa","doi":"10.1016/j.recesp.2025.12.007","DOIUrl":"10.1016/j.recesp.2025.12.007","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 6","pages":"Pages 520-521"},"PeriodicalIF":5.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148178494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intervención coronaria percutánea guiada por imagen endovascular para el infarto agudo de miocardio según la clasificación de lesiones ACC/AHA","authors":"Sang Yoon Lee ,&nbsp;Hyun Sung Joh ,&nbsp;Hyun Kuk Kim ,&nbsp;Ju Han Kim ,&nbsp;Young Joon Hong ,&nbsp;Youngkeun Ahn ,&nbsp;Myung Ho Jeong ,&nbsp;Seung Ho Hur ,&nbsp;Doo-Il Kim ,&nbsp;Kiyuk Chang ,&nbsp;Hun Sik Park ,&nbsp;Jang-Whan Bae ,&nbsp;Jin-Ok Jeong ,&nbsp;Yong Hwan Park ,&nbsp;Kyeong-Ho Yun ,&nbsp;Chang-Hwan Yoon ,&nbsp;Yisik Kim ,&nbsp;Jin-Yong Hwang ,&nbsp;Hyo-Soo Kim ,&nbsp;Woochan Kwon ,&nbsp;Joo Myung Lee","doi":"10.1016/j.recesp.2025.11.016","DOIUrl":"10.1016/j.recesp.2025.11.016","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Despite the favorable prognosis associated with intravascular imaging (IVI)-guided percutaneous coronary intervention (PCI) for complex coronary lesions, it is still unclear whether IVI-guided PCI for such lesions provides clinical benefit in patients with acute myocardial infarction (AMI) according to the ACC/AHA lesion classification.</div></div><div><h3>Methods</h3><div>This study was a patient-level pooled analysis of 2 nationwide Korean AMI registries. We identified 23 051 patients from KAMIR-V and KAMIR-NIH who underwent successful PCI for an infarct-related artery and stratified them by the ACC/AHA lesion classification. Clinical outcomes were compared between IVI-guided and angiography-guided PCI. The primary endpoint was major adverse cardiac events (MACE), a composite of cardiac death, AMI, repeat revascularization, and stent thrombosis, at 3 years.</div></div><div><h3>Results</h3><div>IVI-guided PCI demonstrated a lower incidence of MACE compared with angiography-guided PCI in patients with type B2/C lesions (adjusted HR, 0.78; 95%CI, 0.70-0.88; <em>P</em> &lt;<!--> <!-->.001), but not in patients with type A/B1 lesions (adjusted HR, 0.81, 95%CI, 0.60-1.11; <em>P</em> <!-->=<!--> <!-->.190). In both non–ST-segment elevation myocardial infarction and ST-segment elevation myocardial infarction, a significantly lower risk of MACE following IVI-guided PCI than angiography-guided PCI was observed in patients with type B2/C lesions (non–ST-segment elevation myocardial infarction: adjusted HR, 0.73; 95%CI, 0.63-0.84; <em>P</em> &lt;<!--> <!-->.001; ST-segment elevation myocardial infarction: adjusted HR, 0.86, 95%CI, 0.75-0.98; <em>P</em> <!-->=<!--> <!-->.027), but not in those with type A/B1 lesions.</div></div><div><h3>Conclusions</h3><div>Among patients with AMI, IVI-guided PCI was associated with a significantly lower risk of MACE in those with type B2/C lesions, but not in those with type A/B1 lesions. The prognostic benefit of IVI-guided PCI increased with greater lesion complexity in the infarct-related artery.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 6","pages":"Pages 534-544"},"PeriodicalIF":5.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148190371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impacto del pretratamiento con inhibidores del receptor P2Y12 sobre el infarto de miocardio periprocedimental (tipo 4a) y la hemorragia en el IAMSEST","authors":"Matteo Armillotta ,&nbsp;Francesca Bodega ,&nbsp;Luca Bergamaschi ,&nbsp;Pasquale Paolisso ,&nbsp;Marta Belmonte ,&nbsp;Francesco Angeli ,&nbsp;Damiano Fedele ,&nbsp;Sara Amicone ,&nbsp;Lisa Canton ,&nbsp;Angelo Sansonetti ,&nbsp;Daniele Cavallo ,&nbsp;Francesco Pio Tattilo ,&nbsp;Ornella Di Iuorio ,&nbsp;Khrystyna Ryabenko ,&nbsp;Nicolò Vasumini ,&nbsp;Angelo Maida ,&nbsp;Michele Di Leo ,&nbsp;Tommaso Manaresi ,&nbsp;Marco Basile ,&nbsp;Andrea Rinaldi ,&nbsp;Carmine Pizzi","doi":"10.1016/j.recesp.2025.11.019","DOIUrl":"10.1016/j.recesp.2025.11.019","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Although widely used in clinical practice, pretreatment with a P2Y₁₂ inhibitor in patients with non–ST-segment elevation myocardial infarction (NSTEMI) remains controversial and is not recommended by current guidelines. This study aimed to evaluate the impact of P2Y₁₂ inhibitor pretreatment on the incidence of periprocedural (type 4a) myocardial infarction (MI) and in-hospital bleeding in NSTEMI patients undergoing percutaneous coronary intervention (PCI).</div></div><div><h3>Methods</h3><div>Consecutive NSTEMI patients undergoing PCI were enrolled from the AMIPE multicenter registry (<span><span>NCT03883711</span><svg><path></path></svg></span>) and stratified based on pretreatment strategy according to European Society of Cardiology (ESC) guideline timelines. Patients whose P2Y₁₂ inhibitor administration did not comply with contemporaneous ESC recommendations were excluded. The analysis compared patients treated before and after the 2020 ESC recommendation against routine pretreatment. The primary efficacy endpoint was type 4a MI, and the primary safety endpoint was in-hospital bleeding defined as Bleeding Academic Research Consortium (BARC) types 2, 3, and 5.</div></div><div><h3>Results</h3><div>A total of 1254 patients were included, of whom 740 (59.0%) received pretreatment, mainly with clopidogrel (91.2%). Type 4a MI occurred in 15.2% of patients, with no significant difference between the pretreatment and no pretreatment groups (15.9% vs 14.2%; aOR, 1.08; <em>P</em> <!-->=<!--> <!-->.638). In contrast, in-hospital bleeding was significantly higher in the pretreatment group (7.7% vs 3.9%; aOR, 2.17; <em>P</em> <!-->=<!--> <!-->.005), mainly due to BARC type 2 events.</div></div><div><h3>Conclusions</h3><div>In NSTEMI patients undergoing PCI, pretreatment with P2Y₁₂ inhibitors, mainly clopidogrel, did not reduce the incidence of type 4a MI but was associated with an increased risk of in-hospital bleeding.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 6","pages":"Pages 557-567"},"PeriodicalIF":5.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148190268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Miotomía percutánea para reducir la obstrucción del tracto de salida del ventrículo izquierdo: experiencia inicial","authors":"Sara Sóñora-López ,&nbsp;Yassin Belahnech ,&nbsp;Gerard Martí-Aguasca ,&nbsp;Laura Galián-Gay ,&nbsp;Rubén Fernández-Galera ,&nbsp;Bruno García del Blanco","doi":"10.1016/j.recesp.2025.10.007","DOIUrl":"10.1016/j.recesp.2025.10.007","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 6","pages":"Pages 573-576"},"PeriodicalIF":5.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148190267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Afianzando el valor de los iSGLT2 en pacientes que reciben un implante percutáneo de válvula aórtica","authors":"Pablo Domínguez-Erquicia ,&nbsp;Sergio Raposeiras-Roubín","doi":"10.1016/j.recesp.2025.11.023","DOIUrl":"10.1016/j.recesp.2025.11.023","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 6","pages":"Pages 508-509"},"PeriodicalIF":5.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148190373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"El sistema de litotricia LithiX para el tratamiento de la calcificación coronaria grave: experiencia inicial en la práctica clínica real","authors":"Marcelo Rodríguez-Murillo ,&nbsp;Elena Izaga-Torralba ,&nbsp;Alfonso Jurado-Román ,&nbsp;Ignacio Gallo-Fernández ,&nbsp;Andrés Sánchez-Pérez ,&nbsp;Ignacio J. Amat-Santos","doi":"10.1016/j.recesp.2025.10.003","DOIUrl":"10.1016/j.recesp.2025.10.003","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 6","pages":"Pages 570-573"},"PeriodicalIF":5.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148178493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Manifestaciones cardiovasculares en 54 fumadores crónicos de metanfetamina en Europa","authors":"Núria Ribas Barquet ,&nbsp;Núria Merino Montoliu ,&nbsp;August Supervia Caparrós ,&nbsp;Ana Rodríguez Campello ,&nbsp;Diego Álvaro Pérez Zerpa ,&nbsp;José Carreras Mora","doi":"10.1016/j.recesp.2025.10.013","DOIUrl":"10.1016/j.recesp.2025.10.013","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 6","pages":"Pages 576-578"},"PeriodicalIF":5.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148190254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disección coronaria espontánea confirmada con técnicas de imagen no invasivas","authors":"Teresa Bastante,&nbsp;Beatriz López-Melgar,&nbsp;Fernando Alfonso","doi":"10.1016/j.recesp.2025.09.004","DOIUrl":"10.1016/j.recesp.2025.09.004","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 6","pages":"Pages 579-580"},"PeriodicalIF":5.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148190255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Espacios verdes urbanos, riesgo cardiovascular y mortalidad entre los residentes de una misma zona: estudio de cohortes retrospectivo y actualizado en Corea del Sur","authors":"Sun Jae Park ,&nbsp;Jun Hwan Kim ,&nbsp;Sumin Seo ,&nbsp;Jiwon Yu ,&nbsp;Jihun Song ,&nbsp;Hye Jun Kim ,&nbsp;Sangwoo Park ,&nbsp;Seogsong Jeong ,&nbsp;Sang Min Park","doi":"10.1016/j.recesp.2025.11.002","DOIUrl":"10.1016/j.recesp.2025.11.002","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Previous studies have reported an inverse association between the extent of green space and the risk of cardiovascular disease (CVD). However, longitudinal research focusing on individuals residing within the same geographic area remains scarce. Moreover, comprehensive investigations evaluating the impact of urban green space (UGS) on both CVD incidence and cardiovascular mortality are limited.</div></div><div><h3>Methods</h3><div>This retrospective cohort study used data from the National Health Insurance Service National Sample Cohort. We included 74 925 individuals aged ≥ 20 years residing in 7 metropolitan cities in South Korea, who maintained consistent residential addresses throughout the study period. UGS exposure was quantified as the area of UGS per 1000 residents in 2010. Participants were followed up from January 1, 2011 to December 31, 2019. Cox proportional hazard regression analysis was conducted to evaluate the risk of CVD and mortality, adjusting for potential confounders, including lifestyle behaviors.</div></div><div><h3>Results</h3><div>The highest UGS coverage was associated with a reduced risk of CVD (aHR,<!--> <!-->0.84; 95%<span>C</span>I, 0.77-0.91), with a significant trend (<em>P</em> for trend<!--> <!-->&lt;<!--> <!-->.001). These overall trends remained consistent among various CVD subtypes. A reduced cardiovascular mortality risk was observed in the highest UGS coverage group (aHR,<!--> <!-->0.74; 95%CI, 0.56-0.97).</div></div><div><h3>Conclusions</h3><div>This study identified an association between higher levels of UGS coverage and a reduced risk of both CVD and CVD-related mortality. The study holds significant value in focusing on individuals residing within the same area. Therefore, UGS should be considered as a key factor in future urban planning efforts to reduce the burden of CVD and associated mortality.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 6","pages":"Pages 510-519"},"PeriodicalIF":5.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148190252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antagonista del receptor de la angiotensina II frente a inhibidor de la neprilisina y el receptor de la angiotensina en la IC mejorada con valores estabilizados de NT-proBNP","authors":"Minjung Bak ,&nbsp;Yoonjee Park ,&nbsp;Darae Kim ,&nbsp;Heayoung Shin ,&nbsp;David Hong ,&nbsp;Jeong Hoon Yang ,&nbsp;Jin-Oh Choi","doi":"10.1016/j.recesp.2025.11.017","DOIUrl":"10.1016/j.recesp.2025.11.017","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>The management of heart failure (HF) with improved ejection fraction remains unresolved, particularly after stabilization. This study aimed to determine whether maintenance with an angiotensin receptor-neprilysin inhibitor (ARNI) was superior to de-escalation to an angiotensin receptor blocker (ARB).</div></div><div><h3>Methods</h3><div>In this open-label, prospective pilot study conducted at the Samsung Medical Center in Seoul, South Korea, 98 patients with HF with improved ejection fraction who were stabilized on ARNI were randomized using a block allocation table to either switch to an ARB or continue with an ARNI. The primary outcome was a change in N-terminal pro b-type natriuretic peptide (NT-proBNP) during the follow-up period. The secondary outcomes were defined as: <em>a)</em> NT-proBNP increase, and <em>b)</em> HF admission. Additionally, a post-hoc composite outcome was evaluated, defined as the occurrence of any of the following: NT-proBNP increase, HF admission, left ventricular ejection fraction reduction, or left ventricular end-diastolic volume increase.</div></div><div><h3>Results</h3><div>Baseline characteristics did not differ significantly between the de-escalation group (n<!--> <!-->=<!--> <!-->49) and the maintenance group (n<!--> <!-->=<!--> <!-->49) including NT-proBNP levels (<em>P</em> <!-->=<!--> <!-->.765). During follow-up, NT-proBNP levels remained comparable at 6 and 12 months (<em>P</em> <!-->=<!--> <!-->.642 and <em>P</em> <!-->=<!--> <!-->.964). Secondary outcomes, including the post-hoc composite outcome, did not differ significantly between the groups.</div></div><div><h3>Conclusions</h3><div>This study demonstrates no significant difference in worsening HF indices or clinical outcomes between ARB de-escalation and ARNI maintenance in patients with HF with improved ejection fraction and stabilized NT-proBNP levels. These findings suggest the potential for flexible medication management, although further validation is needed.</div><div>(ClinicalTrials.gov number: <span><span>NCT04803175</span><svg><path></path></svg></span>).</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 6","pages":"Pages 545-556"},"PeriodicalIF":5.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148190269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}