Revista espanola de cardiologia最新文献

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Inhibición dual del SGLT1 y SGLT2: algo más que su suma SGLT1 和 SGLT2 的双重抑制作用:超过两者之和。
IF 5.9 2区 医学
Revista espanola de cardiologia Pub Date : 2024-07-01 DOI: 10.1016/j.recesp.2024.01.005
Enrique Sánchez-Muñoz , Juan Antonio Requena-Ibáñez , Juan José Badimón
{"title":"Inhibición dual del SGLT1 y SGLT2: algo más que su suma","authors":"Enrique Sánchez-Muñoz , Juan Antonio Requena-Ibáñez , Juan José Badimón","doi":"10.1016/j.recesp.2024.01.005","DOIUrl":"10.1016/j.recesp.2024.01.005","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"77 7","pages":"Pages 510-514"},"PeriodicalIF":5.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139631262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Grupos de morbilidad ajustada y valoración geriátrica integral en el paciente mayor con síndrome coronario agudo 急性冠状动脉综合征老年患者的调整发病率分组和老年综合评估
IF 5.9 2区 医学
Revista espanola de cardiologia Pub Date : 2024-07-01 DOI: 10.1016/j.recesp.2024.01.008
Albert Ariza-Solé , Francesc Formiga , David Monterde , Emili Vela , Elena Calvo , Josep Comín-Colet
{"title":"Grupos de morbilidad ajustada y valoración geriátrica integral en el paciente mayor con síndrome coronario agudo","authors":"Albert Ariza-Solé , Francesc Formiga , David Monterde , Emili Vela , Elena Calvo , Josep Comín-Colet","doi":"10.1016/j.recesp.2024.01.008","DOIUrl":"10.1016/j.recesp.2024.01.008","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"77 7","pages":"Pages 589-591"},"PeriodicalIF":5.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139879802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
En reconocimiento del origen español del CRISPR/Cas9. Implicaciones para el tratamiento de las cardiopatías familiares 纪念 CRISPR/Cas9 的西班牙起源。对治疗家族性心脏病的意义。
IF 5.9 2区 医学
Revista espanola de cardiologia Pub Date : 2024-07-01 DOI: 10.1016/j.recesp.2024.01.012
María Sabater Molina , Juan Ramón Gimeno Blanes
{"title":"En reconocimiento del origen español del CRISPR/Cas9. Implicaciones para el tratamiento de las cardiopatías familiares","authors":"María Sabater Molina , Juan Ramón Gimeno Blanes","doi":"10.1016/j.recesp.2024.01.012","DOIUrl":"10.1016/j.recesp.2024.01.012","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"77 7","pages":"Pages 597-598"},"PeriodicalIF":5.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140521901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Balón liberador de sirolimus en el tratamiento del síndrome coronario agudo y crónico: el estudio PEACE, un subanálisis del registro EASTBOURNE 治疗急慢性冠状动脉综合征的西罗莫司涂层球囊:EASTBOURNE 研究的子分析
IF 5.9 2区 医学
Revista espanola de cardiologia Pub Date : 2024-07-01 DOI: 10.1016/j.recesp.2023.11.013
Alessandra Laricchia , Irene Bossi , Roberto A. Latini , Chuey Y. Lee , Ignacio S. Pérez , Fabrizio Tomai , Amin A. Nuruddin , Dario Buccheri , Giuseppe Seresini , Raymundo Ocaranza , Gunasekaran Sengottvelu , Nicola Pesenti , Antonio Mangieri , Bernardo Cortese , en representación de los investigadores del estudio EASTBOURNE
{"title":"Balón liberador de sirolimus en el tratamiento del síndrome coronario agudo y crónico: el estudio PEACE, un subanálisis del registro EASTBOURNE","authors":"Alessandra Laricchia ,&nbsp;Irene Bossi ,&nbsp;Roberto A. Latini ,&nbsp;Chuey Y. Lee ,&nbsp;Ignacio S. Pérez ,&nbsp;Fabrizio Tomai ,&nbsp;Amin A. Nuruddin ,&nbsp;Dario Buccheri ,&nbsp;Giuseppe Seresini ,&nbsp;Raymundo Ocaranza ,&nbsp;Gunasekaran Sengottvelu ,&nbsp;Nicola Pesenti ,&nbsp;Antonio Mangieri ,&nbsp;Bernardo Cortese ,&nbsp;en representación de los investigadores del estudio EASTBOURNE","doi":"10.1016/j.recesp.2023.11.013","DOIUrl":"10.1016/j.recesp.2023.11.013","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>The PEACE study (Performance of a sirolimus-eluting balloon strategy in acute and chronic coronary syndromes) investigated for the first time whether a sirolimus-coated balloon (SCB) (Magic Touch, Concept Medical, India) is associated with different outcomes depending on whether it is used in acute coronary syndromes (ACS) or chronic coronary syndromes (CCS).</p></div><div><h3>Methods</h3><p>This was a post-hoc analysis from the all-comers EASTBOURNE Registry (<span>NCT03085823</span><svg><path></path></svg>). Out of 2083 patients enrolled, an SCB was used to treat 968 (46.5%) ACS and 1115 (53.5%) CCS patients. The primary endpoint was target lesion revascularization at 12 months, while secondary endpoints were angiographic success and major adverse cardiovascular events.</p></div><div><h3>Results</h3><p>Baseline demographics, mean reference vessel diameter and mean lesion length were comparable between ACS and CCS. Predilatation was more commonly performed in ACS (<em>P</em> <!-->=<!--> <!-->.007). SCB was inflated at a standard pressure in both groups with a slight trend toward longer inflation time in ACS. Angiographic success was high in both groups (ACS 97.4% vs CCS 97.7%, <em>P</em> <!-->=<!--> <!-->.820) with limited bailout stenting. Similarly, at 12 months the cumulative incidence of target lesion revascularization (ACS 6.6% vs CCS 5.2%, <em>P</em> <!-->=<!--> <!-->.258) was comparable between ACS and CCS. Conversely, a higher rate of major adverse cardiovascular events in acute presenters was mainly driven by myocardial infarction recurrencies (ACS 10.4% vs CCS 8.3%, <em>P</em> <!-->=<!--> <!-->.009). In-stent restenosis showed a higher proportion of target lesion revascularization and major adverse cardiovascular events than de novo lesions, independently of the type of presentation at the index procedure.</p></div><div><h3>Conclusions</h3><p>This SCB shows good performance in terms of acute and 1-year outcomes independently of the clinical presentation.</p></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"77 7","pages":"Pages 527-536"},"PeriodicalIF":5.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140280377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impacto del uso previo de antiagregantes plaquetarios en la susceptibilidad, la progresión y la gravedad de la COVID-19: un estudio poblacional 先前使用抗血小板药物对 COVID-19 易感性、进展和严重程度的影响:一项基于人群的研究。
IF 5.9 2区 医学
Revista espanola de cardiologia Pub Date : 2024-07-01 DOI: 10.1016/j.recesp.2023.12.012
Ángela Prieto-Campo , Maruxa Zapata-Cachafeiro , Manuel Portela-Romero , María Piñeiro-Lamas , Adolfo Figueiras , Ángel Salgado-Barreira
{"title":"Impacto del uso previo de antiagregantes plaquetarios en la susceptibilidad, la progresión y la gravedad de la COVID-19: un estudio poblacional","authors":"Ángela Prieto-Campo ,&nbsp;Maruxa Zapata-Cachafeiro ,&nbsp;Manuel Portela-Romero ,&nbsp;María Piñeiro-Lamas ,&nbsp;Adolfo Figueiras ,&nbsp;Ángel Salgado-Barreira","doi":"10.1016/j.recesp.2023.12.012","DOIUrl":"10.1016/j.recesp.2023.12.012","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Hypercoagulability and thromboembolism are processes that arise from severe acute respiratory syndrome coronavirus 2 infection and are responsible for a high degree of coronavirus disease 2019 (COVID-19)-related morbidity and mortality. This study sought to assess the effect of antiplatelet drugs on COVID-19 severity (risk of hospitalization and mortality), susceptibility to severe acute respiratory syndrome coronavirus 2 infection, and progression to severe COVID-19.</p></div><div><h3>Methods</h3><p>We conducted a population-based case-control study in a northwestern region of Spain in 2020. The study involved 3060 participants with a positive polymerase chain reaction test who were hospitalized, 26 757 participants with a positive polymerase chain reaction test who were not hospitalized, and 56 785 healthy controls.</p></div><div><h3>Results</h3><p>Triflusal seemed to be associated with a significant increase in risk of hospitalization (aOR, 1.97; 95%<span>C</span>I, 1.27-3.04) and susceptibility to infection (OR, 1.45; 95%CI, 1.07-1.96). It also appeared to lead to a nonsignificant increase in the risk of mortality (OR, 2.23; 95%CI, 0.89-5.55) and/or progression to more severe disease stages (OR, 1.42; 95%CI, 0.8-2.51). Aspirin seemed to be associated with a statistically significant decrease in susceptibility to severe acute respiratory syndrome coronavirus 2 infection (OR, 0.92; 95%CI, 0.86-0.98).</p></div><div><h3>Conclusions</h3><p>Triflusal use appears to increase the risk of susceptibility to COVID-19 infection and an even higher risk of hospitalization, whereas the other antiplatelets could be associated with a reduction in the risk of the various outcomes or have no effect on risk. These findings could support reconsideration of triflusal prescription in COVID-19 pandemic situations.</p></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"77 7","pages":"Pages 539-546"},"PeriodicalIF":5.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S0300893223005420/pdfft?md5=11dd102338e22969e5ae455791b06f7e&pid=1-s2.0-S0300893223005420-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139828792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tiempo de realización de la resonancia magnética cardiaca y valor diagnóstico en pacientes con infarto de miocardio sin obstrucción de arterias coronarias 心脏核磁共振成像的时机和对无冠状动脉阻塞的心肌梗死患者的诊断价值
IF 5.9 2区 医学
Revista espanola de cardiologia Pub Date : 2024-07-01 DOI: 10.1016/j.recesp.2023.11.009
Gladys Juncà , Albert Teis , Gizem Kasa , Elena Ferrer-Sistach , Nuria Vallejo , Jorge López-Ayerbe , Germán Cediel , Antoni Bayés-Genís , Victoria Delgado
{"title":"Tiempo de realización de la resonancia magnética cardiaca y valor diagnóstico en pacientes con infarto de miocardio sin obstrucción de arterias coronarias","authors":"Gladys Juncà ,&nbsp;Albert Teis ,&nbsp;Gizem Kasa ,&nbsp;Elena Ferrer-Sistach ,&nbsp;Nuria Vallejo ,&nbsp;Jorge López-Ayerbe ,&nbsp;Germán Cediel ,&nbsp;Antoni Bayés-Genís ,&nbsp;Victoria Delgado","doi":"10.1016/j.recesp.2023.11.009","DOIUrl":"10.1016/j.recesp.2023.11.009","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>The present study sought to establish the diagnostic yield of cardiovascular magnetic resonance (CMR) in a large cohort of patients admitted with myocardial infarction (MI) with nonobstructive coronary artery disease (MINOCA) based on the timing of referral to CMR.</p></div><div><h3>Methods</h3><p>Consecutive patients referred to CMR from January 2009 to February 2022 with a working diagnosis of MINOCA were retrospectively evaluated. Cine, T<sub>2</sub>-weighted, early, and late gadolinium-enhanced images were acquired and analyzed. The frequency of the underlying diagnosis and the association between timing of CMR and relative frequency of each diagnosis were assessed.</p></div><div><h3>Results</h3><p>We included 207 patients (median age 50 years, 60% men). Final diagnosis after CMR was achieved in 91% of the patients (myocarditis in 45%, MI in 20%, tako-tsubo cardiomyopathy in 19%, and other cardiomyopathies in 7%). The performance of CMR within 7 days of admission with MINOCA (median, 5 days; 117 patients) allowed a higher diagnostic yield compared with CMR performed later (median, 10 days; 88 patients) (96% vs 86%, <em>P</em> <!-->=<!--> <!-->.02). Although myocarditis was the most frequent diagnosis in both groups according to time to CMR, its frequency was higher among patients with a CMR performed within the first 7 days (53% vs 35%, <em>P</em> <!-->=<!--> <!-->.02). The frequency of other underlying diagnoses was not influenced by CMR timing.</p></div><div><h3>Conclusions</h3><p>CMR led to an underlying diagnosis of MINOCA in 91% of patients and its diagnostic yield increased to 96% when CMR was performed within 7 days of admission. The most frequent diagnosis was myocarditis.</p></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"77 7","pages":"Pages 515-523"},"PeriodicalIF":5.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140274515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Métodos de aprendizaje automático para el desarrollo de un modelo predictivo de delirio durante el ingreso en unidades de cuidados intensivos cardiacos 用机器学习方法开发心脏重症监护病房入院期间谵妄的预测模型。
IF 5.9 2区 医学
Revista espanola de cardiologia Pub Date : 2024-07-01 DOI: 10.1016/j.recesp.2023.12.015
Ryoung-Eun Ko , Jihye Lee , Sungeun Kim , Joong Hyun Ahn , Soo Jin Na , Jeong Hoon Yang
{"title":"Métodos de aprendizaje automático para el desarrollo de un modelo predictivo de delirio durante el ingreso en unidades de cuidados intensivos cardiacos","authors":"Ryoung-Eun Ko ,&nbsp;Jihye Lee ,&nbsp;Sungeun Kim ,&nbsp;Joong Hyun Ahn ,&nbsp;Soo Jin Na ,&nbsp;Jeong Hoon Yang","doi":"10.1016/j.recesp.2023.12.015","DOIUrl":"10.1016/j.recesp.2023.12.015","url":null,"abstract":"<div><h3>Introduction and objectives</h3><p>Delirium, recognized as a crucial prognostic factor in the cardiac intensive care unit (CICU), has evolved in response to the changing demographics among critically ill cardiac patients. This study aimed to create a predictive model for delirium for patients in the CICU.</p></div><div><h3>Methods</h3><p>This study included consecutive patients admitted to the CICU of the Samsung Medical Center. To assess the candidate variables for the model: we applied the following machine learning methods: random forest, extreme gradient boosting, partial least squares, and Plmnet-elastic.net. After selecting relevant variables, we performed a logistic regression analysis to derive the model formula. Internal validation was conducted using 100-repeated hold-out validation.</p></div><div><h3>Results</h3><p>We analyzed 2774 patients, 677 (24.4%) of whom developed delirium in the CICU. Machine learning-based models showed good predictive performance. Clinically significant and frequently important predictors were selected to construct a delirium prediction scoring model for CICU patients. The model included albumin level, international normalized ratio, blood urea nitrogen, white blood cell count, C-reactive protein level, age, heart rate, and mechanical ventilation. The model had an area under the receiver operating characteristics curve (AUROC) of 0.861 (95%CI, 0.843-0.879). Similar results were obtained in internal validation with 100-repeated cross-validation (AUROC, 0.854; 95%CI, 0.826-0.883).</p></div><div><h3>Conclusions</h3><p>Using variables frequently ranked as highly important in four machine learning methods, we created a novel delirium prediction model. This model could serve as a useful and simple tool for risk stratification for the occurrence of delirium at the patient's bedside in the CICU.</p></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"77 7","pages":"Pages 547-555"},"PeriodicalIF":5.9,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140088056","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cierre de orejuela guiado por ecocardiografía intracardiaca cuatridimensional 四维心内超声心动图引导下的心房阑尾闭合术
IF 5.9 2区 医学
Revista espanola de cardiologia Pub Date : 2024-06-27 DOI: 10.1016/j.recesp.2024.06.006
Karim Jamhour-Chelh , Xavier Millán Álvarez , Dabit Arzamendi Aizpurua
{"title":"Cierre de orejuela guiado por ecocardiografía intracardiaca cuatridimensional","authors":"Karim Jamhour-Chelh ,&nbsp;Xavier Millán Álvarez ,&nbsp;Dabit Arzamendi Aizpurua","doi":"10.1016/j.recesp.2024.06.006","DOIUrl":"10.1016/j.recesp.2024.06.006","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"77 12","pages":"Pages 1065-1066"},"PeriodicalIF":5.9,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142720692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ecocardiografía y angiotomografía en el drenaje venoso pulmonar anómalo 异常肺静脉引流的超声心动图和血管造影术
IF 5.9 2区 医学
Revista espanola de cardiologia Pub Date : 2024-06-27 DOI: 10.1016/j.recesp.2024.06.008
Marc Figueras-Coll , Anna Sabaté-Rotés , Queralt Ferrer Menduiña
{"title":"Ecocardiografía y angiotomografía en el drenaje venoso pulmonar anómalo","authors":"Marc Figueras-Coll ,&nbsp;Anna Sabaté-Rotés ,&nbsp;Queralt Ferrer Menduiña","doi":"10.1016/j.recesp.2024.06.008","DOIUrl":"10.1016/j.recesp.2024.06.008","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"77 12","pages":"Pages 1067-1068"},"PeriodicalIF":5.9,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142720693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluación multimodal de un aneurisma de arteria coronaria con fístula arteriovenosa 对伴有动静脉瘘的冠状动脉瘤进行多模式评估
IF 5.9 2区 医学
Revista espanola de cardiologia Pub Date : 2024-06-24 DOI: 10.1016/j.recesp.2024.05.007
Marcos Ferrández-Escarabajal, Solomon W. Bienstock, Gina LaRocca
{"title":"Evaluación multimodal de un aneurisma de arteria coronaria con fístula arteriovenosa","authors":"Marcos Ferrández-Escarabajal,&nbsp;Solomon W. Bienstock,&nbsp;Gina LaRocca","doi":"10.1016/j.recesp.2024.05.007","DOIUrl":"10.1016/j.recesp.2024.05.007","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"77 11","pages":"Page 973"},"PeriodicalIF":5.9,"publicationDate":"2024-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142531772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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