{"title":"La onda P durante la estimulación de vena pulmonar para localizar reconexiones transitoriamente desenmascaradas por adenosina","authors":"Daniel Cantero Lozano , Isabel Cornejo Mazzuchelli , Paloma Lapunzina Soler , M. Teresa Barrio-López , Eduardo Castellanos Martínez , Jesús Almendral","doi":"10.1016/j.recesp.2024.08.005","DOIUrl":"10.1016/j.recesp.2024.08.005","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 2","pages":"Pages 153-156"},"PeriodicalIF":5.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143211115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernando Alfonso , Jorge Salamanca , Iván Núñez-Gil , Náyade Del Prado , Nicolás Rosillo , Javier Elola
{"title":"Tendencias en la frecuentación y mortalidad hospitalaria por síndrome de tako-tsubo en España","authors":"Fernando Alfonso , Jorge Salamanca , Iván Núñez-Gil , Náyade Del Prado , Nicolás Rosillo , Javier Elola","doi":"10.1016/j.recesp.2024.08.007","DOIUrl":"10.1016/j.recesp.2024.08.007","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 2","pages":"Pages 158-160"},"PeriodicalIF":5.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143211341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aneurisma gigante de la arteria pulmonar derecha en el síndrome de Eisenmenger","authors":"Xiang-Ting Lu, Yi-Bing Lu, Hai-Long Dai","doi":"10.1016/j.recesp.2024.08.003","DOIUrl":"10.1016/j.recesp.2024.08.003","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 2","pages":"Pages 161-162"},"PeriodicalIF":5.9,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143211343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zhihao Zheng , Yanjun Song , Zechen Liu , Jining He , Shanshan Shi , Chenxi Song , Rui Fu , Lei Jia , Guofeng Gao , Qiuting Dong , Min Yang , Wenjun Ma , Kefei Dou
{"title":"Calidad del sueño e hipertensión incidental","authors":"Zhihao Zheng , Yanjun Song , Zechen Liu , Jining He , Shanshan Shi , Chenxi Song , Rui Fu , Lei Jia , Guofeng Gao , Qiuting Dong , Min Yang , Wenjun Ma , Kefei Dou","doi":"10.1016/j.recesp.2024.12.002","DOIUrl":"10.1016/j.recesp.2024.12.002","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Poor sleep quality poses significant public health challenges worldwide. This study aimed to investigate the association between sleep quality and the risk of hypertension.</div></div><div><h3>Methods</h3><div>The study analyzed 284 250 adults from the UK Biobank (UKB) and 6104 participants from the English Longitudinal Study of Ageing (ELSA) without hypertension at baseline. The exposure of interest was sleep quality, which was evaluated based on questionnaires. Participants were divided into 3 groups based on the assessment of sleep quality. Sleep duration was assessed by self-reported sleep hours by each participant. The primary endpoint was new onset hypertension.</div></div><div><h3>Results</h3><div>In the UKB cohort, participants with poor sleep quality showed a significantly higher risk of hypertension than those with healthy sleep quality (HR, 1.277; 95%<span>C</span>I, 1.21-1.346]. The results from the ELSA cohort effectively validated those from the UKB cohort; participants with poor sleep quality had a notably heightened risk of hypertension (HR, 1.264; 95%CI, 1.02-1.566). Prolonging sleep duration was associated with a decrease in the risk of hypertension in individuals with intermediate or healthy sleep quality. Although several factors were independently associated with a lower risk of hypertension (<em>P</em> <!--><<!--> <!-->.001), the association between sleep quality and an increased risk of hypertension remained significant regardless of genetic susceptibility to hypertension (<em>P</em> for interaction<!--> <!-->=<!--> <!-->.067).</div></div><div><h3>Conclusions</h3><div>Considering the genetic predisposition to hypertension, poor sleep quality is associated with an elevated risk of hypertension. In intermediate or healthy levels of sleep quality, prolonging sleep duration is linked to a reduced risk of hypertension.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 7","pages":"Pages 600-608"},"PeriodicalIF":5.9,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144481414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fernando Alfonso , Jorge Salamanca , Iván Núñez-Gil , Borja Ibáñez , Juan Sanchis , Manel Sabaté , Maite Velázquez , Sergio Raposeiras-Roubín , Tamara García-Camarero , Paula Antuña , Hernán Mejía , Xavier Carrillo , Irene Buera , Manuel Martínez-Sellés , Juan Manuel Escudier-Villa , Joaquín Sánchez-Prieto , Emilia Blanco Ponce , Gonzalo Cabezón , Covadonga Fernández-Golfín , Domingo Pascual-Figal , Filippo Crea
{"title":"Justificación y diseño del estudio sobre bloqueadores beta en el síndrome de tako-tsubo: un estudio clínico aleatorizado (β-Tako)","authors":"Fernando Alfonso , Jorge Salamanca , Iván Núñez-Gil , Borja Ibáñez , Juan Sanchis , Manel Sabaté , Maite Velázquez , Sergio Raposeiras-Roubín , Tamara García-Camarero , Paula Antuña , Hernán Mejía , Xavier Carrillo , Irene Buera , Manuel Martínez-Sellés , Juan Manuel Escudier-Villa , Joaquín Sánchez-Prieto , Emilia Blanco Ponce , Gonzalo Cabezón , Covadonga Fernández-Golfín , Domingo Pascual-Figal , Filippo Crea","doi":"10.1016/j.recesp.2024.12.008","DOIUrl":"10.1016/j.recesp.2024.12.008","url":null,"abstract":"<div><h3>Introducción y objetivos</h3><div>El síndrome de <em>tako-tsubo</em> (STT) es una entidad cardiaca que simula un síndrome coronario agudo, caracterizada por una disfunción ventricular izquierda transitoria en ausencia de lesiones coronarias culpables. Su etiología es desconocida, pero se postula una disfunción microvascular reversible secundaria a una tormenta catecolaminérgica. El tratamiento es empírico, pero en la práctica clínica la mayoría de los pacientes reciben bloqueadores beta (BB). El estudio sobre bloqueadores beta en el STT (β-Tako) es un estudio académico, pragmático, prospectivo, multicéntrico, aleatorizado y abierto con evaluación ciega de acontecimientos, que pretende conocer la eficacia y seguridad de los BB en pacientes con STT.</div></div><div><h3>Métodos</h3><div>El diagnóstico de STT se confirmará por coronariografía invasiva y estudios ecocardiográficos seriados. Se aleatorizarán 200 pacientes con STT (1:1) a BB (n<!--> <!-->=<!--> <!-->100) o no BB (n<!--> <!-->=<!--> <!-->100). Se utilizarán BB con actividad alfa o liberadora de óxido nítrico.</div></div><div><h3>Resultados</h3><div>El objetivo primario de eficacia del estudio es la comparación del índice de puntuación del movimiento parietal por ecocardiografía a los 7 días, analizado en un laboratorio central independiente. También se estudiarán los cambios en la fracción de eyección y en la deformación longitudinal global. Un comité clínico independiente analizará el objetivo clínico combinado (muerte, accidente cerebrovascular, o reingreso por STT recurrente, síndrome coronario agudo, insuficiencia cardiaca o fibrilación auricular) a un año. Se realizarán diversos subestudios predefinidos (clínicos, imagen, biomarcadores, farmacogenéticos, inflamación, ácido ribonucleico mensajero y de calidad de vida).</div></div><div><h3>Conclusiones</h3><div>El estudio β-Tako generará una valiosa evidencia científica sobre aspectos no conocidos del STT, y permitirá guiar las decisiones de abordaje clínico y tratamiento en esta compleja entidad clínica.</div><div>Estudio registrado en EU-CT número: 2023-510213-25-01, <em>ClinicalTrials.gov Identifier</em>, <span><span>NCT06509074</span><svg><path></path></svg></span>.</div></div><div><h3>Introduction y objectives</h3><div>Tako-tsubo syndrome (TTS) is a cardiac condition that mimics acute coronary syndrome, characterized by transient left ventricular dysfunction in the absence of culprit coronary artery stenosis. Although its etiology remains unknown, reversible microvascular dysfunction secondary to an adrenergic surge is thought to play a role. Treatment is empirical, although most patients receive beta-blockers (BB) in clinical practice. The Beta-blockers in Tako-tsubo Syndrome study (<em>β</em>-Tako), is an academic, multicenter, pragmatic, prospective randomized open-label trial with blinded endpoint evaluation that aims to assess the efficacy and safety of BB in patients with TTS.</div></div><div><h3>Methods</h3><div>T","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 7","pages":"Pages 592-599"},"PeriodicalIF":5.9,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144481413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"La Estrategia en Salud Cardiovascular del Sistema Nacional de Salud (ESCAV). Una gran oportunidad y responsabilidad para todos","authors":"Luis Rodríguez Padial , Julián Pérez Villacastín","doi":"10.1016/j.recesp.2025.01.021","DOIUrl":"10.1016/j.recesp.2025.01.021","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 7","pages":"Pages 637-638"},"PeriodicalIF":5.9,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144481501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jose Antonio Esteban-Chapel , Juan Antonio Franco-Peláez , Alvaro Aceña
{"title":"Tratamiento antiagregante en la prevención primaria de lesiones coronarias no significativas","authors":"Jose Antonio Esteban-Chapel , Juan Antonio Franco-Peláez , Alvaro Aceña","doi":"10.1016/j.recesp.2025.01.012","DOIUrl":"10.1016/j.recesp.2025.01.012","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 7","pages":"Pages 590-591"},"PeriodicalIF":5.9,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144481412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Ablación de la vía accesoria en la vena cava superior izquierda persistente","authors":"Finn Åkerström , Astrid Paul-Nordin","doi":"10.1016/j.recesp.2024.12.006","DOIUrl":"10.1016/j.recesp.2024.12.006","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 7","pages":"Page 665"},"PeriodicalIF":5.9,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144481507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joo Myung Lee , Seung Hun Lee , Woochan Kwon , Han Byul Kim , David Hong , Hyun Kuk Kim , Sang-Geon Cho , Doosup Shin , Ki Seong Park , Jahae Kim , Jang Bae Moon , Ho-Chun Song , Seungrok Lee , Dong-Heon Ha , Jinah Jang , Youngkeun Ahn , Myung Ho Jeong , Ki Hong Choi , Taek Kyu Park , Jeong Hoon Yang , Young Joon Hong
{"title":"Validación experimental de la gravedad de la estenosis coronaria y el desarrollo de miocardio isquémico","authors":"Joo Myung Lee , Seung Hun Lee , Woochan Kwon , Han Byul Kim , David Hong , Hyun Kuk Kim , Sang-Geon Cho , Doosup Shin , Ki Seong Park , Jahae Kim , Jang Bae Moon , Ho-Chun Song , Seungrok Lee , Dong-Heon Ha , Jinah Jang , Youngkeun Ahn , Myung Ho Jeong , Ki Hong Choi , Taek Kyu Park , Jeong Hoon Yang , Young Joon Hong","doi":"10.1016/j.recesp.2024.10.006","DOIUrl":"10.1016/j.recesp.2024.10.006","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>The current study aimed to evaluate the causal association between hemodynamically significant stenosis and the occurrence of ischemic myocardium using an experimental animal model of coronary artery stenosis.</div></div><div><h3>Methods</h3><div>In Yorkshire swine (n<!--> <!-->=<!--> <!-->10), coronary stenosis in the left anterior descending artery was induced using a customized vascular occluder to create varying degrees of occlusion severity (40%-99%). Serial changes in coronary pressure and flow velocity were measured in the left anterior descending artery before and after the implantation of the vascular occluder. At 1 month, <sup>13</sup>N-ammonia positron emission tomography (PET) was performed, followed by the collection of isolated hearts for 2,3,5-Triphenyltetrazolium chloride (TTC) staining to quantify the percent area of necrotic myocardium. Three animals in the control group were evaluated using the same protocols, but without the implantation of a vascular occluder.</div></div><div><h3>Results</h3><div>The median diameter stenosis after vascular occluder implantation was 61.3% (Q1-Q3: 55.9%-72.3%). Significant differences were observed in hyperemic stenosis resistance, fractional flow reserve (FFR), stress perfusion defect and reversibility in PET, as well as in necrotic myocardium in TTC staining based on stenosis severity (control group: <<!--> <!-->50%, 50%-70%, 70%-90%, and ><!--> <!-->90%) (all <em>P</em> <!--><<!--> <!-->.010). Animals with FFR <<!--> <!-->0.75 at 1 month exhibited a significantly higher area of stress perfusion defect (30.7<!--> <!-->±<!--> <!-->3.1% vs 6.0<!--> <!-->±<!--> <!-->4.2%, <em>P</em> <!--><<!--> <!-->.001), reversibility in PET (11.0<!--> <!-->±<!--> <!-->4.0% vs 0.0<!--> <!-->±<!--> <!-->0.0%, <em>P</em> <!-->=<!--> <!-->.006), and necrotic myocardium in TTC staining (15.8<!--> <!-->±<!--> <!-->6.4% vs 0.0<!--> <!-->±<!--> <!-->0.0%, <em>P</em> <!--><<!--> <!-->.001) than those with FFR ≥ 0.75.</div></div><div><h3>Conclusions</h3><div>In a porcine model, the induction of hemodynamically significant stenosis with FFR <<!--> <!-->0.75 was associated with the development of stress perfusion defects and reversibility in PET, as well as necrotic myocardium identified by pathology.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"78 6","pages":"Pages 521-532"},"PeriodicalIF":5.9,"publicationDate":"2025-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144134694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}