Néstor Báez-Ferrer , Marc Abril-Pla , Anas Waleed Al-Hayani-Al-Hantoosh , Pablo Avanzas , Alberto Domínguez-Rodríguez
{"title":"Valor pronóstico de la hipertensión arterial pulmonar combinada en la cirugía de insuficiencia mitral","authors":"Néstor Báez-Ferrer , Marc Abril-Pla , Anas Waleed Al-Hayani-Al-Hantoosh , Pablo Avanzas , Alberto Domínguez-Rodríguez","doi":"10.1016/j.recesp.2025.10.001","DOIUrl":"10.1016/j.recesp.2025.10.001","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 6","pages":"Pages 568-570"},"PeriodicalIF":5.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148178492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Omar Obeidat , Ahmad Alayyat , Abdallah Naser , Fares Ghanem , Ahmad Jabri , Milos Brankovic , Tianze Jiao , Mohammed Ruzieh , Alaq Haddad , Tamas Alexy , Pedro Villablanca , Laith Alhuneafat
{"title":"Impacto de los inhibidores de SGLT2 en los resultados a largo plazo en pacientes con insuficiencia cardiaca sometidos a TAVI: un análisis de emparejamiento por propensión","authors":"Omar Obeidat , Ahmad Alayyat , Abdallah Naser , Fares Ghanem , Ahmad Jabri , Milos Brankovic , Tianze Jiao , Mohammed Ruzieh , Alaq Haddad , Tamas Alexy , Pedro Villablanca , Laith Alhuneafat","doi":"10.1016/j.recesp.2025.10.014","DOIUrl":"10.1016/j.recesp.2025.10.014","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Sodium-glucose cotransporter-2 inhibitors (SGLT2i) improve outcomes in heart failure (HF), but their role in patients undergoing transcatheter aortic valve implantation (TAVI) remains unclear. A recent randomized trial (DapaTAVI) showed reduced HF hospitalizations with SGLT2i post-TAVI, but effects on mortality and broader outcomes are unknown.</div></div><div><h3>Methods</h3><div>Using the TriNetX Research Network, we conducted a multicenter retrospective cohort study of adults with HF who underwent TAVI between 2015 and 2025. Patients prescribed SGLT2i within 30 days of TAVI were 1:1 propensity score-matched to nonusers. The primary outcome was all-cause mortality; secondary outcomes included hospitalizations, myocardial infarction, stroke, arrhythmias, and renal events.</div></div><div><h3>Results</h3><div>Among 58 193 TAVI recipients, 3022 SGLT2i users were matched to 3022 nonusers. SGLT2i use was associated with significantly lower mortality at 3 months (3.5% vs 4.9%; HR, 0.71), 6 months (5.0% vs 8.1%; HR, 0.61), 12 months (7.3% vs 10.5%; HR, 0.71), and 5 years (10.7% vs 20.6%; HR, 0.59; all <em>P</em> <<!--> <!-->.01). SGLT2i users also had fewer hospital or emergency room visits and a lower 5-year incidence of myocardial infarction (12.0% vs 14.4%; OR, 0.81; <em>P</em> <!-->=<!--> <!-->.007). Stroke incidence was lower at 6 months (4.8% vs 6.1%; <em>P</em> <!-->=<!--> <!-->.041) but was not sustained long term. Renal and arrhythmic outcomes were similar between groups.</div></div><div><h3>Conclusions</h3><div>SGLT2i use in patients with HF undergoing TAVI was associated with reduced mortality and fewer adverse cardiovascular events. These findings support the integration of SGLT2i into post-TAVI management strategies.</div><div><em>Full English text available from</em>:<span><span>www.revespcardiol.org/en</span><svg><path></path></svg></span></div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 6","pages":"Pages 498-507"},"PeriodicalIF":5.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148190372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mensajes clave de los estudios ARTESiA y NOAH sobre la fibrilación auricular subclínica","authors":"Juan Benezet-Mazuecos , Jeff S. Healey","doi":"10.1016/j.recesp.2025.07.005","DOIUrl":"10.1016/j.recesp.2025.07.005","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 3","pages":"Pages 280-282"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147413144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pilar Molina , Benito Morentin , Paloma Hevia , Ana Monzó , Joaquín S. Lucena
{"title":"Muerte súbita por embolia pulmonar en adultos jóvenes españoles. Estudio retrospectivo multicéntrico de 128 autopsias forenses","authors":"Pilar Molina , Benito Morentin , Paloma Hevia , Ana Monzó , Joaquín S. Lucena","doi":"10.1016/j.recesp.2025.08.010","DOIUrl":"10.1016/j.recesp.2025.08.010","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Pulmonary embolism (PE) may debut as sudden death (SD) in young and middle-aged adults. This study aims to determine the epidemiological and clinicopathological characteristics involved in SD due to PE in this age group and the underlying risk factors.</div></div><div><h3>Methods</h3><div>Multicenter retrospective noncontrolled study based on forensic autopsies performed in individuals aged 12 to 49 years at 3 forensic pathology services in Spain (Valencia, Biscay, and Seville) over an 8-year period (2010-2017).</div></div><div><h3>Results</h3><div>A total of 1344 cardiac SD cases were recorded, of which 128 (9.5%) were due to PE (57% male, median age 42 years). The annual incidence was 0.56/100 000 inhabitants/y. The main risk factor was obesity (62%; 18.5% morbid obesity). The mean body mass index was 34.9<!--> <!-->±<!--> <!-->13.1. Psychiatric disorders were highly prevalent (44%). Immobilization (26%) and prior trauma (11%) were other relevant antecedents. Among women, 22% were receiving oral contraceptive therapy. Premortem symptoms were reported in 52% of cases, mainly dyspnea (56%). Although 22 individuals sought medical attention, only one was correctly diagnosed. Toxicological analysis was performed in 67% of cases, with positive results for psychotropic drugs (20%) and substances of abuse/alcohol (9%).</div></div><div><h3>Conclusions</h3><div>PE is a common cause of SD in individuals younger than 50 years and is frequently clinically underdiagnosed. This study provides evidence supporting a strong association with obesity and psychiatric disorders, which facilitate immobilization, venous stasis, and a prothrombotic state. Forensic studies of SD due to PE offer complementary data to clinical research, revealing risk factors that are underrepresented in clinical cohorts.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 3","pages":"Pages 237-246"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147413523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Artur Dziewierz , Giuseppe Biondi-Zoccai , Zbigniew Siudak
{"title":"Contaminación del aire e infarto de miocardio en España: consideraciones metodológicas y contexto clínico ampliado","authors":"Artur Dziewierz , Giuseppe Biondi-Zoccai , Zbigniew Siudak","doi":"10.1016/j.recesp.2025.09.006","DOIUrl":"10.1016/j.recesp.2025.09.006","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 3","pages":"Pages 285-286"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147413137","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jesús Blázquez Camacho , Viviana Arreo del Val , Luz Polo López
{"title":"Neonato cianótico: reto diagnóstico resuelto por imagen","authors":"Jesús Blázquez Camacho , Viviana Arreo del Val , Luz Polo López","doi":"10.1016/j.recesp.2025.08.009","DOIUrl":"10.1016/j.recesp.2025.08.009","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 3","pages":"Pages 283-284"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147413143","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contaminación del aire e infarto de miocardio en España: consideraciones metodológicas y contexto clínico ampliado. Respuesta","authors":"Jordi Bañeras , Julio Núñez , Cristina Fernández","doi":"10.1016/j.recesp.2025.10.008","DOIUrl":"10.1016/j.recesp.2025.10.008","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 3","pages":"Pages 286-287"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147413145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jorge Sanz Sánchez , José Antonio Sorolla Romero , Jean Paul Vílchez Tschischke , Carles Fonfria , Ignacio J. Amat Santos , José Luis Díez Gil
{"title":"Alineación comisural con la bioprótesis aórtica percutánea Allegra","authors":"Jorge Sanz Sánchez , José Antonio Sorolla Romero , Jean Paul Vílchez Tschischke , Carles Fonfria , Ignacio J. Amat Santos , José Luis Díez Gil","doi":"10.1016/j.recesp.2025.05.008","DOIUrl":"10.1016/j.recesp.2025.05.008","url":null,"abstract":"","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 3","pages":"Pages 278-280"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147413141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martín Romo , Claudia Yuste , Jorge Vélez , Miguel Hernández , Beatriz Palacios , Raquel Pita , Margarita Capel , Sandra Fernández Fernández , Nicolás Rosillo , Guillermo Moreno , Manuel del Oro , Carmen Ortega , José L. Bernal , Héctor Bueno
{"title":"Resultados clínicos, uso de recursos sanitarios y costes según la función renal en pacientes con insuficiencia cardiaca","authors":"Martín Romo , Claudia Yuste , Jorge Vélez , Miguel Hernández , Beatriz Palacios , Raquel Pita , Margarita Capel , Sandra Fernández Fernández , Nicolás Rosillo , Guillermo Moreno , Manuel del Oro , Carmen Ortega , José L. Bernal , Héctor Bueno","doi":"10.1016/j.recesp.2025.08.014","DOIUrl":"10.1016/j.recesp.2025.08.014","url":null,"abstract":"<div><h3>Introduction and objectives</h3><div>Chronic kidney disease is highly prevalent in patients with heart failure (HF), increases clinical complexity, and worsens prognosis. This study quantitatively assessed the impact of renal dysfunction severity, including dialysis, on clinical outcomes, resource utilization, and costs in patients with HF.</div></div><div><h3>Methods</h3><div>Retrospective cohort study in adult patients with 1 emergency department visit or hospitalization with an HF diagnosis in a university hospital in 2018. One-year clinical outcomes, resources, and costs were compared with the COHERENT (Clinical outcomes, healthcare resource utilization, and related costs) model according to estimated glomerular filtration rate (eGFR) ≥ 60, 30 to 59, 15 to 29, and <<!--> <!-->15 (including patients on dialysis) mL/min/1.73 m<sup>2</sup>.</div></div><div><h3>Results</h3><div>Of 3274 patients with HF (median age, 84 years; 56% women), 1453 (44.4%) had eGFR ≥ 60. Lower eGFR levels were associated with higher 1-year mortality (20.4% in eGFR ≥ 60 vs 45.4% in eGFR 15 to 29; <em>P</em> <<!--> <!-->.001 for trend), rehospitalization, and new emergency department visits. Patients with eGFR <<!--> <!-->15 had the highest readmission rate (50.8%; <em>P</em> <<!--> <!-->.001 for trend). Days out of hospital without dialysis decreased from 292 (80.0%) in eGFR ≥ 60 to 184 (50.3%) in eGFR <<!--> <!-->15. Median cost per patient journey increased from €3960 (Q1-Q3, €1750 to €8410) with eGFR ≥ 60 to €9590 (Q1-Q3, €4140 to €28 520; <em>P</em> <<!--> <!-->.001) with eGFR <<!--> <!-->15, driven mainly by hospitalizations (84%-90% of total, except for eGFR <<!--> <!-->15, 59.0%).</div></div><div><h3>Conclusions</h3><div>Renal dysfunction severity was associated with progressively worse clinical outcomes, increased health resource utilization, and higher costs in patients with HF. Strategies are needed to improve outcomes and reduce costs in patients with HF and severe chronic kidney disease.</div></div>","PeriodicalId":21299,"journal":{"name":"Revista espanola de cardiologia","volume":"79 3","pages":"Pages 247-256"},"PeriodicalIF":5.9,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147413520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}